Tech Jobs in San Mateo, CA

1,130,167 open positions · Updated daily

San Mateo sits on the edge of Silicon Valley, offering easy access to BART and a walkable downtown with cafes, parks, and coworking hubs. The city hosts a vibrant mix of startups, Fortune 500 tech firms, and research labs, drawing talent from Stanford, UC Berkeley, and major tech schools nearby.

Tech roles range from cloud infrastructure and AI research to fintech product management and cybersecurity architecture. Companies such as Salesforce, Adobe, Twitter, and Uber maintain regional offices, while emerging startups like Scribe and Sinequa build products in healthtech and search AI. Biotech firms in nearby Redwood City and biotech incubators in San Mateo’s Hillsdale area further diversify the ecosystem.

Living costs are high: median home price exceeds $1.4 million and the average rent for a 1‑bedroom apartment is around $3,200/month. Salary transparency lets candidates compare offers, negotiate effectively, and align compensation with the cost of living and local market rates.

Outside Machinist

Company: Construction Services LLC

Location: San Diego, CA

Posted Oct 01, 2025

Must have the ability to read and interpret mechanical drawings, written instructions/technical manuals. Ability to safely use hand and power tools and portable…

Pharmacist - Transplant

Company: UCLA Health

Location: Los Angeles, CA

Posted Oct 01, 2025

Pharm D. degree and current CA Pharmacy license. Demonstrated ability to speak in front of large groups to present didactic course material or scientific data.

RN, Registered Nurse - ICU Pediatric

Company: Christus Health

Location: San Antonio, TX

Posted Oct 01, 2025

Continues to develop the ability to cope with and manage contingencies of clinical nursing. RN License in state of employment or compact.

RN, Registered Nurse Clinic - Pedi Cardiology

Company: Christus Health

Location: San Antonio, TX

Posted Oct 01, 2025

RN license in good standing in state of employment or a compact state , if applicable. Addresses psychological, emotional, cultural, and social needs of patient…

Preschool Teacher

Company: Challenger School Foundation

Location: San Jose, CA

Posted Oct 01, 2025

After successful completion of that program, you will be given a classroom of your own to teach and manage. Thoroughly learn Challenger’s curriculum, teaching…

Business Systems Analyst (Hybrid)

Company: Santa Clara Family Health Plan

Location: San Jose, CA

Posted Oct 01, 2025

Bachelor’s Degree in Healthcare, Information Systems, or related field, or equivalent experience, training, or coursework.

Configuration Analyst

Company: Santa Clara Family Health Plan

Location: San Jose, CA

Posted Oct 01, 2025

Combine in-depth analysis of application configuration and data, information gathered through independent research, knowledge of system capabilities and…

Sous Chef

Company: White Lodging

Location: San Antonio, TX

Posted Oct 01, 2025

A passion for coaching, developing talent, and delivering exceptional guest experiences. Organize, oversee, and manage food prep operations, including creating…

Plumber

Company: 5 Star Best Plumbing

Location: San Jose, CA

Posted Oct 01, 2025

Valid driver’s license and clean driving record. Unique marketing strategy for consistent service calls. Our Plumber will be responsible for drain cleaning,…

Elementary Teacher

Company: Challenger School Foundation

Location: San Jose, CA

Posted Oct 01, 2025

Specific teaching degrees and certificates are not required to teach at Challenger School; we will teach you how to teach! Ability to pass a background check.

Customer Enrolment Associate

Company: OSF Communications

Location: San Jose, CA

Posted Oct 01, 2025

This full-time, entry-level role is designed for motivated individuals who want to build a career in sales, customer service, and account management while…

Housekeeper | Janitor

Company: Crestwood Behavioral Health

Location: San Diego, CA

Posted Oct 01, 2025

Job Duties: The Housekeeper | Janitor is responsible for assisting with the overall functions of the housekeeping department and maintaining the facility in a…

Frequently Asked Questions

What types of tech jobs are available in San Mateo, CA?
San Mateo hosts roles in software engineering (full‑stack, mobile, data), product management, UX/UI design, DevOps, AI/ML research, cybersecurity, cloud architecture, fintech development, healthtech R&D, and biotech software support.
Are tech jobs in San Mateo remote, on‑site, or hybrid?
The majority (≈65%) of openings require on‑site presence in Downtown or Hillsdale, but 30% offer hybrid schedules and 5% are fully remote, reflecting the city’s mix of legacy firms and agile startups.
Who are the major employers in San Mateo?
Key employers include Salesforce, Adobe, Twitter, Uber, Lyft, Palantir, and regional offices of Google, LinkedIn, and Meta. Startups such as Scribe, Sinequa, and local biotech incubator companies also dominate hiring.
What are the salary expectations for tech roles in San Mateo?
Base salaries for software engineers begin at $110,000 and average $150,000–$170,000 for senior roles; product managers average $135,000–$160,000; data scientists average $145,000; cybersecurity roles average $140,000–$165,000. Total compensation often includes bonuses, RSUs, and benefits.
What should I know before relocating to San Mateo for tech work?
Plan for high housing costs—factor in $3,200 monthly rent or $1.4 million median home price. Evaluate commute options: BART, Caltrain, and local bus routes serve downtown. Research local coworking spaces, networking events, and community groups like San Mateo Tech Meetups to ease transition.

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