Tech Jobs in San Mateo, CA

1,130,789 open positions · Updated daily

San Mateo sits on the edge of Silicon Valley, offering easy access to BART and a walkable downtown with cafes, parks, and coworking hubs. The city hosts a vibrant mix of startups, Fortune 500 tech firms, and research labs, drawing talent from Stanford, UC Berkeley, and major tech schools nearby.

Tech roles range from cloud infrastructure and AI research to fintech product management and cybersecurity architecture. Companies such as Salesforce, Adobe, Twitter, and Uber maintain regional offices, while emerging startups like Scribe and Sinequa build products in healthtech and search AI. Biotech firms in nearby Redwood City and biotech incubators in San Mateo’s Hillsdale area further diversify the ecosystem.

Living costs are high: median home price exceeds $1.4 million and the average rent for a 1‑bedroom apartment is around $3,200/month. Salary transparency lets candidates compare offers, negotiate effectively, and align compensation with the cost of living and local market rates.

Clinical Pharmacist

Company: Methodist Hospital Texsan

Location: San Antonio, TX

Posted Aug 18, 2025

You will supervise technical support personnel in drug preparation and distribution systems and participates in competency training for technical personnel.

Plumbing Service Customer Service Representative

Company: Christianson A/C & Plumbing

Location: San Antonio, TX

Posted Aug 18, 2025

The ideal Candidate will be very organized, have some knowledge in Microsoft Office products including Word, Excel, and Outlook, have a strong attention to…

Sales Associate - Beverly Center

Company: Kenzo

Location: Los Angeles, CA

Posted Aug 18, 2025

Facilitate and develop lasting relationships with clients to increase client retention. Capture all relevant customer information for entry in database.

Resource Float Registered Nurse

Company: Methodist Hospital

Location: San Antonio, TX

Posted Aug 18, 2025

Education assistance (tuition, student loan, certification support, dependent scholarships). Minimum of six (6) months of clinical experience as a licensed…

Luxury Sales

Company: Haus of Portraiture

Location: Santa Monica, CA

Posted Aug 18, 2025

You will be responsible for driving sales growth by effectively engaging with customers, understanding their needs, and providing tailored solutions.

Registered Nurse Case Manager

Company: Melodia Care Hospice

Location: Hayward, CA

Posted Aug 18, 2025

Must be a licensed driver with an automobile that is insured in accordance with state/or. Registered nurses shall have a minimum of (a) one (1) year of…

Security Guard - Healthcare Patrol Specialist

Company: Allied Universal

Location: San Jose, CA

Posted Aug 18, 2025

A valid driver's license will be required for driving positions only. As a condition of employment, applicants will be subject to a background investigation in…

Resource Float Registered Nurse

Company: Methodist Hospital

Location: San Antonio, TX

Posted Aug 18, 2025

Education assistance (tuition, student loan, certification support, dependent scholarships). Minimum of six (6) months of clinical experience as a licensed…

Kitchen Chef

Company: Kiwami

Location: Studio City, CA

Posted Aug 18, 2025

Monitor and maintain cleanliness, sanitation and organization of assigned station and service areas. 2 years experience as a restaurant cook.

Clinical Nurse II - 0.9 - Days - Med Surg 1 @ LG

Company: El Camino Hospital

Location: Los Gatos, CA

Posted Aug 18, 2025

Applies nursing process and theories, as well as principles of psycho-social and physical sciences, in assessing, planning, diagnosing, implementing, evaluating…

Registered Nurse RN Mother Baby

Company: Methodist Children's Hospital

Location: San Antonio, TX

Posted Aug 18, 2025

If Compact license, a Texas RN license is required within 60 days of hire date. As a Registered Nurse, you will be responsible for delivering high-quality,…

Frequently Asked Questions

What types of tech jobs are available in San Mateo, CA?
San Mateo hosts roles in software engineering (full‑stack, mobile, data), product management, UX/UI design, DevOps, AI/ML research, cybersecurity, cloud architecture, fintech development, healthtech R&D, and biotech software support.
Are tech jobs in San Mateo remote, on‑site, or hybrid?
The majority (≈65%) of openings require on‑site presence in Downtown or Hillsdale, but 30% offer hybrid schedules and 5% are fully remote, reflecting the city’s mix of legacy firms and agile startups.
Who are the major employers in San Mateo?
Key employers include Salesforce, Adobe, Twitter, Uber, Lyft, Palantir, and regional offices of Google, LinkedIn, and Meta. Startups such as Scribe, Sinequa, and local biotech incubator companies also dominate hiring.
What are the salary expectations for tech roles in San Mateo?
Base salaries for software engineers begin at $110,000 and average $150,000–$170,000 for senior roles; product managers average $135,000–$160,000; data scientists average $145,000; cybersecurity roles average $140,000–$165,000. Total compensation often includes bonuses, RSUs, and benefits.
What should I know before relocating to San Mateo for tech work?
Plan for high housing costs—factor in $3,200 monthly rent or $1.4 million median home price. Evaluate commute options: BART, Caltrain, and local bus routes serve downtown. Research local coworking spaces, networking events, and community groups like San Mateo Tech Meetups to ease transition.

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