Tech Jobs in San Mateo, CA

1,130,899 open positions · Updated daily

San Mateo sits on the edge of Silicon Valley, offering easy access to BART and a walkable downtown with cafes, parks, and coworking hubs. The city hosts a vibrant mix of startups, Fortune 500 tech firms, and research labs, drawing talent from Stanford, UC Berkeley, and major tech schools nearby.

Tech roles range from cloud infrastructure and AI research to fintech product management and cybersecurity architecture. Companies such as Salesforce, Adobe, Twitter, and Uber maintain regional offices, while emerging startups like Scribe and Sinequa build products in healthtech and search AI. Biotech firms in nearby Redwood City and biotech incubators in San Mateo’s Hillsdale area further diversify the ecosystem.

Living costs are high: median home price exceeds $1.4 million and the average rent for a 1‑bedroom apartment is around $3,200/month. Salary transparency lets candidates compare offers, negotiate effectively, and align compensation with the cost of living and local market rates.

Home Infusion Nurse (RN)

Company: Grace H

Location: Redwood City, CA

Posted Aug 18, 2025

Valid driver’s license and auto insurance. Current BLS certification and NSO Insurance / Proof of TB. Advanced certification such as ACLS, PALS, CEN, TNCC is a…

Analyst - AI Trainer

Company: DataAnnotation

Location: San Antonio, TX

Posted Aug 18, 2025

You can work on your own schedule. You will measure the progress of these AI chatbots, evaluate their logic, and solve problems to improve the quality of each…

Custodian – Laboratory Facilities

Company: PharmLabs LLC

Location: San Diego, CA

Posted Aug 18, 2025

PharmLabs is a state-of-the-art DEA-registered and ISO/IEC 17025-accredited analytical testing laboratory specializing in cannabinoids, peptides, kratom, and…

Unarmed Security Officer – Open Interviews 8/20

Company: Platinum Security

Location: San Diego, CA

Posted Aug 18, 2025

Knowledge of first aid and CPR certification is advantageous. The ideal candidate will play a crucial role in maintaining a safe and secure environment for our…

Unarmed Security Officer - Day Shift

Company: Platinum Security

Location: Poway, CA

Posted Aug 18, 2025

Respond promptly and professionally to incidents as needed. At least 1 year of security experience required. _*\*MUST HAVE VALID GUARD AND CPR*_.

Math Teacher - AI Trainer

Company: DataAnnotation

Location: Chula Vista, CA

Posted Aug 18, 2025

You can work on your own schedule. You will measure the progress of these AI chatbots, evaluate their logic, and solve problems to improve the quality of each…

Journeyman Plumber

Company: John Ciampoli Plumbing

Location: Spring Valley, CA

Posted Aug 18, 2025

In-depth knowledge of plumbing tools and procedures. Preparing and maintaining the right tools for a job. Performing routine inspections and testing of plumbing…

Senior Manager, Patient Access Marketing

Company: Travere Therapeutics

Location: San Diego, CA

Posted Aug 18, 2025

Partner closely with the sales and field reimbursement teams to evolve materials, messaging, and resources to support a seamless field and customer experience.

Security Officer

Company: Westin San Diego Bayview

Location: San Diego, CA

Posted Aug 18, 2025

Assist guests to their rooms or help guests enter their rooms. Approach all encounters with guests and employees in a friendly service oriented manner.

Construction Worker, Rebuild

Company: Samaritan's Purse

Location: Pasadena, CA

Posted Aug 18, 2025

Inspect all jobs, ensuring work is performed per federal, state, and local laws and codes. Trade certifications (electrical, plumbing, roofing, framing, and…

Analyst - AI Trainer

Company: DataAnnotation

Location: Los Angeles, CA

Posted Aug 18, 2025

You can work on your own schedule. You will measure the progress of these AI chatbots, evaluate their logic, and solve problems to improve the quality of each…

Frequently Asked Questions

What types of tech jobs are available in San Mateo, CA?
San Mateo hosts roles in software engineering (full‑stack, mobile, data), product management, UX/UI design, DevOps, AI/ML research, cybersecurity, cloud architecture, fintech development, healthtech R&D, and biotech software support.
Are tech jobs in San Mateo remote, on‑site, or hybrid?
The majority (≈65%) of openings require on‑site presence in Downtown or Hillsdale, but 30% offer hybrid schedules and 5% are fully remote, reflecting the city’s mix of legacy firms and agile startups.
Who are the major employers in San Mateo?
Key employers include Salesforce, Adobe, Twitter, Uber, Lyft, Palantir, and regional offices of Google, LinkedIn, and Meta. Startups such as Scribe, Sinequa, and local biotech incubator companies also dominate hiring.
What are the salary expectations for tech roles in San Mateo?
Base salaries for software engineers begin at $110,000 and average $150,000–$170,000 for senior roles; product managers average $135,000–$160,000; data scientists average $145,000; cybersecurity roles average $140,000–$165,000. Total compensation often includes bonuses, RSUs, and benefits.
What should I know before relocating to San Mateo for tech work?
Plan for high housing costs—factor in $3,200 monthly rent or $1.4 million median home price. Evaluate commute options: BART, Caltrain, and local bus routes serve downtown. Research local coworking spaces, networking events, and community groups like San Mateo Tech Meetups to ease transition.

Related Pages