Tech Jobs in San Mateo, CA

1,130,899 open positions · Updated daily

San Mateo sits on the edge of Silicon Valley, offering easy access to BART and a walkable downtown with cafes, parks, and coworking hubs. The city hosts a vibrant mix of startups, Fortune 500 tech firms, and research labs, drawing talent from Stanford, UC Berkeley, and major tech schools nearby.

Tech roles range from cloud infrastructure and AI research to fintech product management and cybersecurity architecture. Companies such as Salesforce, Adobe, Twitter, and Uber maintain regional offices, while emerging startups like Scribe and Sinequa build products in healthtech and search AI. Biotech firms in nearby Redwood City and biotech incubators in San Mateo’s Hillsdale area further diversify the ecosystem.

Living costs are high: median home price exceeds $1.4 million and the average rent for a 1‑bedroom apartment is around $3,200/month. Salary transparency lets candidates compare offers, negotiate effectively, and align compensation with the cost of living and local market rates.

Frontend Engineer - HealthTech

Company: Beacon Talent

Location: Los Angeles, CA

Posted Aug 15, 2025

Familiarity with backend integration (GraphQL/REST APIs) and state management (Redux, Zustand, etc.). Strong design instincts with an ability to create visually…

M&A Hybrid Cloud Infrastructure Senior Manager

Company: Deloitte

Location: San Diego, CA

Posted Aug 15, 2025

We modernize core infrastructure, networks, and AI platforms from the data center to the edge and develop new infrastructure and device services that help…

Staff Software Engineer - AMR Planning & Controls

Company: General Motors

Location: Mountain View, CA

Posted Aug 15, 2025

Contribute to testing and validation workflows, including simulation (SIL), hardware-in-the-loop (HIL), and field testing.

Frontend Engineer - HealthTech

Company: Beacon Talent

Location: Burbank, CA

Posted Aug 15, 2025

Familiarity with backend integration (GraphQL/REST APIs) and state management (Redux, Zustand, etc.). Strong design instincts with an ability to create visually…

RN, Registered Nurse PreOp/PACU-Ambulatory Surgery Center

Company: Christus Health

Location: San Antonio, TX

Posted Aug 15, 2025

Continues to develop the ability to cope with and manage contingencies of clinical nursing. RN License in state of employment or compact.

Frontend Engineer - HealthTech

Company: Beacon Talent

Location: San Diego, CA

Posted Aug 15, 2025

Familiarity with backend integration (GraphQL/REST APIs) and state management (Redux, Zustand, etc.). Strong design instincts with an ability to create visually…

RN, Registered Nurse Float PIII - Nursing Float Pool

Company: Christus Health

Location: San Antonio, TX

Posted Aug 15, 2025

Continues to develop the ability to cope with and manage contingencies of clinical nursing. Knowledge of federal, state and local healthcare-related laws and…

RN, Registered Nurse-Ambulatory Surgery Center

Company: Christus Health

Location: San Antonio, TX

Posted Aug 15, 2025

Continues to develop the ability to cope with and manage contingencies of clinical nursing. RN License in state of employment or compact.

RN, Registered Nurse - Acute MedSurgical B

Company: Christus Health

Location: San Antonio, TX

Posted Aug 15, 2025

Continues to develop the ability to cope with and manage contingencies of clinical nursing. RN License in state of employment or compact.

M&A Hybrid Cloud Infrastructure Senior Manager

Company: Deloitte

Location: San Antonio, TX

Posted Aug 15, 2025

We modernize core infrastructure, networks, and AI platforms from the data center to the edge and develop new infrastructure and device services that help…

Shop Carpenter

Company: San Francisco Playhouse

Location: Hayward, CA

Posted Aug 15, 2025

Valid driver’s license and ability to transport tools and scenic elements between locations (preferred). This job entails collaborating closely with designers…

Principal Software Engineer – Vehicle Experiences Engine Software

Company: General Motors

Location: Mountain View, CA

Posted Aug 15, 2025

Lead and generate technical solutions including specifying requirements, functional decomposition, analysis, design, development, and testing for Infotainment…

Frequently Asked Questions

What types of tech jobs are available in San Mateo, CA?
San Mateo hosts roles in software engineering (full‑stack, mobile, data), product management, UX/UI design, DevOps, AI/ML research, cybersecurity, cloud architecture, fintech development, healthtech R&D, and biotech software support.
Are tech jobs in San Mateo remote, on‑site, or hybrid?
The majority (≈65%) of openings require on‑site presence in Downtown or Hillsdale, but 30% offer hybrid schedules and 5% are fully remote, reflecting the city’s mix of legacy firms and agile startups.
Who are the major employers in San Mateo?
Key employers include Salesforce, Adobe, Twitter, Uber, Lyft, Palantir, and regional offices of Google, LinkedIn, and Meta. Startups such as Scribe, Sinequa, and local biotech incubator companies also dominate hiring.
What are the salary expectations for tech roles in San Mateo?
Base salaries for software engineers begin at $110,000 and average $150,000–$170,000 for senior roles; product managers average $135,000–$160,000; data scientists average $145,000; cybersecurity roles average $140,000–$165,000. Total compensation often includes bonuses, RSUs, and benefits.
What should I know before relocating to San Mateo for tech work?
Plan for high housing costs—factor in $3,200 monthly rent or $1.4 million median home price. Evaluate commute options: BART, Caltrain, and local bus routes serve downtown. Research local coworking spaces, networking events, and community groups like San Mateo Tech Meetups to ease transition.

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