Tech Jobs in St. Louis, MO

61,348 open positions · Updated daily

St. Louis is becoming a tech hub thanks to a blend of healthcare innovation, a strong manufacturing base, and a growing fintech scene. With 14,708 tech openings, the city offers a mix of high‑growth startups and established firms, all powered by a talent pool fed by universities such as Saint Louis University and Washington University.

Key sectors driving the market include healthtech—home to life‑science giants like BJC HealthCare and Eli Lilly—financial technology, logistics software, and data analytics. Companies like Enterprise Holdings, Vontel, and the City of St. Louis use cutting‑edge platforms to streamline operations, while startups in the Central West End and Midtown districts are hiring full‑stack developers, AI/ML engineers, and cybersecurity specialists.

While the cost of living in St. Louis remains 15% below the national average, median rent for a one‑bedroom apartment in Midtown is around $1,200 and the median home price sits near $225,000. Transparent salary listings let candidates evaluate whether a role’s pay aligns with local living expenses—ensuring you can afford the lifestyle you want without hidden surprises.

Shift Lead

Company: Walgreens

Location: Hannibal, MO

Posted Jan 24, 2025

The job involves managing store operations, including opening and closing the store, handling cash, managing inventory, and ensuring a positive customer experience. Responsibilities also include coaching team members, maintaining store cleanliness, and ensuring compliance with regulations. The role requires leadership experience, fluency in English, and knowledge of store systems. Preferred qualifications include experience with store inventory control.

Beauty and Wellness Consultant

Company: Walgreens

Location: Saint Joseph, MO

Posted Jan 24, 2025

The job description outlines responsibilities for a Beauty Consultant at Walgreens, focusing on maximizing sales and brand awareness through exceptional customer service. Key tasks include providing personalized advice, conducting mini-makeovers and skincare consultations, and leading in-store events. The role involves achieving sales goals, maintaining department standards, and engaging with customers through various channels. The ideal candidate should have retail sales experience, product knowledge, and strong interpersonal skills. Fluency in English is required, and a cosmetology or esthetician license is preferred. Walgreens, as a leading pharmacy-led health and wellbeing enterprise, offers a supportive work environment and opportunities for career growth.

Pharmacy Customer Service Associate

Company: Walgreens

Location: Chesterfield, MO

Posted Jan 24, 2025

Customer Service Associate

Company: Walgreens

Location: St. Louis, MO

Posted Jan 24, 2025

Sales Management Trainee

Company: Enterprise Mobility

Location: Chesterfield, MO

Posted Jan 24, 2025

Independent Optometrist - Walmart

Company: Walmart

Location: St. Cloud, MN

Posted Jan 24, 2025

The text describes a job opportunity for an Independent Optometrist leasing space inside Walmart stores. The role involves leading patient care in eye and vision care, as well as general health and well-being. The optometrist has autonomy over their practice hours, patient schedule, and fee schedule, retaining 100% of exam/professional fees. They can opt into additional services like equipment/instrumentation and administrative support. Minimum qualifications include a Doctor of Optometry (OD) or Ophthalmologist (MD or DO) degree, valid state license, and insurance certificates. The job is not an employment position with Walmart Inc., but a lease agreement.

Occupational Therapist

Company: UnitedHealth Group

Location: Kansas City, MO

Posted Jan 24, 2025

Shift Lead

Company: Walgreens

Location: O'Fallon, MO

Posted Jan 24, 2025

Principal Field Solution Architect - Enterprise Networking Solutions

Company: CDW

Location: St. Louis, MO

Posted Jan 24, 2025

CDW is a Fortune 200 leader where driven professionals and technology experts solve IT challenges. The Principal Field Solution Architect (FSA) role focuses on Enterprise Networking presales solution design, working with internal and external sales teams to plan and organize sales strategies. The Principal FSA is a field-based technical presales role, expected to spend the majority of their time onsite at CDW customer locations. They are responsible for driving initiatives, coaching and mentoring others, and uncovering emerging business opportunities. The Principal FSA is a subject matter expert in multiple families of Enterprise Networking solutions, and is expected to be on the forefront of their solutions and implications for CDW offerings.

Frequently Asked Questions

What types of tech jobs are available in St. Louis, MO?
St. Louis offers roles from software engineering and data science to cybersecurity, DevOps, UI/UX design, AI/ML research, and product management. The city’s healthtech and fintech sectors demand specialists in electronic health records, blockchain, and regulatory tech, while logistics firms need supply‑chain analytics and IoT developers.
How do remote and on‑site trends look in St. Louis?
Many companies now support hybrid models, with on‑site work preferred for roles that require collaboration, such as product design or systems engineering. Pure remote positions are common in software development and data analysis. Companies like Enterprise and Vontel offer flexible schedules, but a 3‑day on‑site requirement is typical for senior engineering roles.
Who are the major employers in St. Louis?
Key employers include BJC HealthCare, Enterprise Holdings, Eli Lilly & Co., Vontel, City of St. Louis, and the St. Louis Science Center’s research labs. Additionally, the city’s startup ecosystem includes companies such as Glean, Tasty, and the Midtown tech incubator, all actively hiring tech talent.
What are salary expectations for tech roles in St. Louis?
Median base salary for software engineers in St. Louis is around $95,000, with senior roles reaching $120,000+. Data scientists average $98,000, while cybersecurity analysts earn $88,000. These figures exceed the national average for comparable roles, reflecting the city’s focus on high‑growth industries. Transparent listings on Job Transparency help you benchmark offers against local market rates.
What advice is there for relocating to St. Louis for tech work?
Plan your move by researching neighborhoods: Midtown and the Central West End offer vibrant tech scenes and affordable housing; the St. Louis Riverfront and Oakville provide quieter options with easy access to downtown. Use Job Transparency’s salary tool to confirm that offers cover living costs. When interviewing, ask about relocation packages, housing stipends, and the company’s remote policy. Finally, tap local networking groups such as the St. Louis Tech Council and meetups to accelerate integration.

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