Tech Jobs in St. Louis, MO

61,352 open positions · Updated daily

St. Louis is becoming a tech hub thanks to a blend of healthcare innovation, a strong manufacturing base, and a growing fintech scene. With 14,708 tech openings, the city offers a mix of high‑growth startups and established firms, all powered by a talent pool fed by universities such as Saint Louis University and Washington University.

Key sectors driving the market include healthtech—home to life‑science giants like BJC HealthCare and Eli Lilly—financial technology, logistics software, and data analytics. Companies like Enterprise Holdings, Vontel, and the City of St. Louis use cutting‑edge platforms to streamline operations, while startups in the Central West End and Midtown districts are hiring full‑stack developers, AI/ML engineers, and cybersecurity specialists.

While the cost of living in St. Louis remains 15% below the national average, median rent for a one‑bedroom apartment in Midtown is around $1,200 and the median home price sits near $225,000. Transparent salary listings let candidates evaluate whether a role’s pay aligns with local living expenses—ensuring you can afford the lifestyle you want without hidden surprises.

Pharmacy Technician / Pharm Tech Apprenticeship

Company: Walgreens

Location: Kansas City, MO

Posted Jan 24, 2025

Walgreens is transforming its pharmacy technician roles to a more patient-centric environment. As a Pharmacy Technician or Apprentice, you'll interact with customers, develop strong patient relationships, and have access to the latest technology to grow your career. Walgreens offers an 'earn while you learn' Pharmacy Technician Training Program, recognized by ASHP and the Department of Labor, which guides you towards becoming a PTCB Certified Pharmacy Technician. The role involves assisting pharmacists, using pharmacy systems, maintaining customer service, and adhering to state and federal regulations. Walgreens provides training and opportunities for personal development, including PTCB certification and continuing education credits.

Independent Optometrist - Walmart

Company: Walmart

Location: St. Louis, MO

Posted Jan 24, 2025

Pharmacy Cashier

Company: Walgreens

Location: Saint Joseph, MO

Posted Jan 24, 2025

Sales Management Trainee

Company: Enterprise Mobility

Location: St. Louis, MO

Posted Jan 24, 2025

Shift Lead

Company: Walgreens

Location: O'Fallon, MO

Posted Jan 24, 2025

The job involves managing store operations, including opening and closing the store, handling cash, managing inventory, and ensuring a positive customer experience. Responsibilities also include coaching team members, maintaining store cleanliness, and complying with company policies. The role requires leadership experience, fluency in English, and knowledge of store systems. Preferred qualifications include experience with store inventory control.

H&M Sales Associate

Company: H&M

Location: St. Petersburg, FL

Posted Jan 24, 2025

At H&M, a Retail Sales Associate, or Sales Advisor, is responsible for delivering exceptional customer service, maintaining a tidy sales floor, and maximizing selling opportunities. Key duties include greeting customers, assisting with transactions, stocking garments, and promoting the H&M Loyalty program. The role involves teamwork, flexibility, and the ability to lift heavy items. H&M offers a dynamic work environment, growth opportunities, a staff discount, and an inclusive, diverse culture.

Customer Service Associate

Company: Walgreens

Location: Joplin, MO

Posted Jan 24, 2025

Pharmacy Operations Manager

Company: Walgreens

Location: St. Augustine, FL

Posted Jan 24, 2025

The role involves performing day-to-day non-clinical pharmacy operations, administrative tasks, and ensuring efficient workflow for a positive patient experience. The individual will serve as a full-time certified pharmacy technician, operating pharmacy systems, and processing prescriptions under a pharmacist's supervision. They will also supervise pharmacy technicians and cashiers, and be responsible for personnel selection, scheduling, and development. The role includes customer engagement, resolving complaints, and enhancing customer experience. Operations involve assisting in patient care, prescription data entry, and medication preparation. The individual will manage core pharmacy workflow, drive excellence in operations, and ensure compliance with business policies and laws. They will also lead performance management of technicians, including hiring, onboarding, training, and scheduling. The role requires maintaining PTCB certification and enhancing current pharmacy and healthcare knowledge.

Shift Lead

Company: Walgreens

Location: Maryland Heights, MO

Posted Jan 24, 2025

Emerging Store Manager

Company: Walgreens

Location: O'Fallon, MO

Posted Jan 24, 2025

Frequently Asked Questions

What types of tech jobs are available in St. Louis, MO?
St. Louis offers roles from software engineering and data science to cybersecurity, DevOps, UI/UX design, AI/ML research, and product management. The city’s healthtech and fintech sectors demand specialists in electronic health records, blockchain, and regulatory tech, while logistics firms need supply‑chain analytics and IoT developers.
How do remote and on‑site trends look in St. Louis?
Many companies now support hybrid models, with on‑site work preferred for roles that require collaboration, such as product design or systems engineering. Pure remote positions are common in software development and data analysis. Companies like Enterprise and Vontel offer flexible schedules, but a 3‑day on‑site requirement is typical for senior engineering roles.
Who are the major employers in St. Louis?
Key employers include BJC HealthCare, Enterprise Holdings, Eli Lilly & Co., Vontel, City of St. Louis, and the St. Louis Science Center’s research labs. Additionally, the city’s startup ecosystem includes companies such as Glean, Tasty, and the Midtown tech incubator, all actively hiring tech talent.
What are salary expectations for tech roles in St. Louis?
Median base salary for software engineers in St. Louis is around $95,000, with senior roles reaching $120,000+. Data scientists average $98,000, while cybersecurity analysts earn $88,000. These figures exceed the national average for comparable roles, reflecting the city’s focus on high‑growth industries. Transparent listings on Job Transparency help you benchmark offers against local market rates.
What advice is there for relocating to St. Louis for tech work?
Plan your move by researching neighborhoods: Midtown and the Central West End offer vibrant tech scenes and affordable housing; the St. Louis Riverfront and Oakville provide quieter options with easy access to downtown. Use Job Transparency’s salary tool to confirm that offers cover living costs. When interviewing, ask about relocation packages, housing stipends, and the company’s remote policy. Finally, tap local networking groups such as the St. Louis Tech Council and meetups to accelerate integration.

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