Tech Jobs in St. Louis, MO

61,352 open positions · Updated daily

St. Louis is becoming a tech hub thanks to a blend of healthcare innovation, a strong manufacturing base, and a growing fintech scene. With 14,708 tech openings, the city offers a mix of high‑growth startups and established firms, all powered by a talent pool fed by universities such as Saint Louis University and Washington University.

Key sectors driving the market include healthtech—home to life‑science giants like BJC HealthCare and Eli Lilly—financial technology, logistics software, and data analytics. Companies like Enterprise Holdings, Vontel, and the City of St. Louis use cutting‑edge platforms to streamline operations, while startups in the Central West End and Midtown districts are hiring full‑stack developers, AI/ML engineers, and cybersecurity specialists.

While the cost of living in St. Louis remains 15% below the national average, median rent for a one‑bedroom apartment in Midtown is around $1,200 and the median home price sits near $225,000. Transparent salary listings let candidates evaluate whether a role’s pay aligns with local living expenses—ensuring you can afford the lifestyle you want without hidden surprises.

Store Manager In Training

Company: CVS Health

Location: Branson, MO

Posted Jan 24, 2025

Assistant Manager of Quality

Company: CSL

Location: Columbia, MO

Posted Jan 24, 2025

The Assistant Manager Quality (AMQ) role involves ensuring the center adheres to Standard Operating Procedures, managing the Quality Control program, and overseeing HR policies. The role requires 1 year of supervisory experience, Quality experience, and knowledge of complex regulations. Benefits include health care options, life insurance, disability coverage, 401(k) participation, Paid Time Off, and observed holidays. CSL Plasma, a global organization, values diversity and inclusion.

Member Assist Cart Attendant

Company: Walmart

Location: St. Louis, MO

Posted Jan 24, 2025

Sam's Club is seeking dedicated individuals to join their team as Member Assist - Cart Attendants. The role involves ensuring a positive shopping experience for members, from helping with purchases and loading vehicles to maintaining a clean and organized parking lot. Key responsibilities include thriving in fast-paced environments, prioritizing member satisfaction, and providing exceptional customer service. The position offers competitive pay, performance-based bonuses, and a range of benefits including health, financial, and paid time off. Sam's Club also provides opportunities for career growth and development through their Live Better U education benefit program.

Case Manager RN - Field (Kansas City, KS; University of Kansas Hospital)

Company: CVS Health

Location: Kansas City, MO

Posted Jan 24, 2025

CVS Health is seeking a Community Care Case Manager with a minimum of 3 years of clinical experience, preferably in diabetes, CHF, CKD, post-acute care, hospice, palliative care, or cardiac areas, and 2 years of CM, discharge planning, or home health care coordination experience. The role involves acting as a liaison between members, clients, families, employers, providers, insurance companies, and healthcare personnel. The Case Manager will assess, plan, facilitate, coordinate, evaluate, and advocate for options and services to meet individual health needs. They will also communicate with members, prepare documentation, and interact with internal multidisciplinary teams. The position requires active and unrestricted KS RN license, ability to travel 75% within Kansas City, KS, and proficiency in standard corporate software applications. The pay range is $54,095.60 - $116,760.80.

Member Frontline Cashier

Company: Walmart

Location: Jefferson City, MO

Posted Jan 24, 2025

Meat Cutter and Wrapper

Company: Walmart

Location: Maryland Heights, MO

Posted Jan 24, 2025

Pharmacy Technician

Company: CVS Health

Location: St. Peters, MO

Posted Jan 24, 2025

CVS Health emphasizes its commitment to human-centric health care, guided by the purpose of 'Bringing our heart to every moment of your health'. The company aims to deliver enhanced, personalized, convenient, and affordable health care solutions. Pharmacy Technicians play a crucial role in this mission, supporting pharmacy teams to ensure smooth operations, accurate prescription fulfillment, and exceptional patient service. Technicians are expected to demonstrate empathy, genuine care, and a growth mindset, contributing to a safe, inclusive, and engaging team dynamic. They must comply with all relevant laws and regulations, and complete necessary training and certification requirements.

Freezer, Cooler and Deli Stocker Associate

Company: Walmart

Location: Maryland Heights, MO

Posted Jan 24, 2025

Sam's Club is seeking a freezer, cooler, and deli stocker. The role involves stocking shelves, maintaining cleanliness, ensuring product quality, and providing excellent customer service. The successful candidate will prioritize member satisfaction, be a problem solver, and adapt well to changes. Benefits include competitive pay, health benefits, 401(k), and various other perks. The hourly wage range is $17.00 to $24.00.

Cafe Associate

Company: Walmart

Location: St. Louis, MO

Posted Jan 24, 2025

Pharmacy Technician

Company: CVS Health

Location: Kansas City, MO

Posted Jan 24, 2025

Freezer, Cooler and Deli Stocker Associate

Company: Walmart

Location: Saint Joseph, MO

Posted Jan 24, 2025

Sam's Club is seeking a freezer, cooler, and deli stocker. The role involves stocking shelves, maintaining cleanliness, ensuring product quality, and providing excellent customer service. The successful candidate will prioritize member satisfaction, be a problem solver, and adapt well to changes. Benefits include competitive pay, health benefits, 401(k), and various other perks. The hourly wage range is $16.00 to $23.00.

Frequently Asked Questions

What types of tech jobs are available in St. Louis, MO?
St. Louis offers roles from software engineering and data science to cybersecurity, DevOps, UI/UX design, AI/ML research, and product management. The city’s healthtech and fintech sectors demand specialists in electronic health records, blockchain, and regulatory tech, while logistics firms need supply‑chain analytics and IoT developers.
How do remote and on‑site trends look in St. Louis?
Many companies now support hybrid models, with on‑site work preferred for roles that require collaboration, such as product design or systems engineering. Pure remote positions are common in software development and data analysis. Companies like Enterprise and Vontel offer flexible schedules, but a 3‑day on‑site requirement is typical for senior engineering roles.
Who are the major employers in St. Louis?
Key employers include BJC HealthCare, Enterprise Holdings, Eli Lilly & Co., Vontel, City of St. Louis, and the St. Louis Science Center’s research labs. Additionally, the city’s startup ecosystem includes companies such as Glean, Tasty, and the Midtown tech incubator, all actively hiring tech talent.
What are salary expectations for tech roles in St. Louis?
Median base salary for software engineers in St. Louis is around $95,000, with senior roles reaching $120,000+. Data scientists average $98,000, while cybersecurity analysts earn $88,000. These figures exceed the national average for comparable roles, reflecting the city’s focus on high‑growth industries. Transparent listings on Job Transparency help you benchmark offers against local market rates.
What advice is there for relocating to St. Louis for tech work?
Plan your move by researching neighborhoods: Midtown and the Central West End offer vibrant tech scenes and affordable housing; the St. Louis Riverfront and Oakville provide quieter options with easy access to downtown. Use Job Transparency’s salary tool to confirm that offers cover living costs. When interviewing, ask about relocation packages, housing stipends, and the company’s remote policy. Finally, tap local networking groups such as the St. Louis Tech Council and meetups to accelerate integration.

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