Tech Jobs in St. Louis, MO

61,353 open positions · Updated daily

St. Louis is becoming a tech hub thanks to a blend of healthcare innovation, a strong manufacturing base, and a growing fintech scene. With 14,708 tech openings, the city offers a mix of high‑growth startups and established firms, all powered by a talent pool fed by universities such as Saint Louis University and Washington University.

Key sectors driving the market include healthtech—home to life‑science giants like BJC HealthCare and Eli Lilly—financial technology, logistics software, and data analytics. Companies like Enterprise Holdings, Vontel, and the City of St. Louis use cutting‑edge platforms to streamline operations, while startups in the Central West End and Midtown districts are hiring full‑stack developers, AI/ML engineers, and cybersecurity specialists.

While the cost of living in St. Louis remains 15% below the national average, median rent for a one‑bedroom apartment in Midtown is around $1,200 and the median home price sits near $225,000. Transparent salary listings let candidates evaluate whether a role’s pay aligns with local living expenses—ensuring you can afford the lifestyle you want without hidden surprises.

Key Carrier Coor

Company: The TJX Companies, Inc.

Location: Columbia, MO

Posted Jan 24, 2025

HomeGoods Store 1197 in Columbia, MO is seeking a flexible, team-oriented Key Carrier. This role involves alternating between Coordinator and Key Carrier duties, requiring open availability including nights and weekends. The Key Carrier will model exceptional customer service, contribute to the growth of their career, and maintain all aspects of the store. Responsibilities include ensuring a positive internal and external customer experience, promoting a culture of honesty and integrity, and adhering to company policies and procedures. The ideal candidate should have 1 year of retail experience and 6 months of leadership experience, with superior communication and organizational skills. HomeGoods values diversity and embraces the unknown, encouraging employees to 'Discover Different'.

Senior Product Manager - Technical

Company: Mastercard

Location: O'Fallon, MO

Posted Jan 24, 2025

Mastercard is seeking a Lead Product Manager-Technical for their Promotions team. The role involves identifying gaps, championing new platform capabilities, determining release goals, and prioritizing features. The ideal candidate should understand business context, customer use cases, and have expertise in platform feature areas. They must also be proficient in grooming user stories, prioritizing backlogs, and communicating effectively with various teams. The position requires adherence to Mastercard's security policies and practices.

Service & Engagement Team Leader

Company: Target

Location: St. Cloud, MN

Posted Jan 24, 2025

Target is offering a competitive pay range of $21.25 - $36.15 per hour, with variations based on factors like labor markets, education, experience, and certifications. The company provides comprehensive benefits including health insurance, 401(k), employee discount, and various leave options. As a Service and Engagement Team Leader, one can expect a dynamic role involving guest service, team leadership, and business operations. Key responsibilities include demonstrating a service culture, leading a team of Guest Advocates, supporting digital and physical offerings, and ensuring a positive guest experience. Target values diversity, equity, and inclusion, and expects team members to uphold ethical conduct, safety, and compliance.

Patient Care Technician

Company: DaVita

Location: Florissant, MO

Posted Jan 24, 2025

Patient Care Technician

Company: DaVita

Location: Raymore, MO

Posted Jan 24, 2025

Patient Care Technician

Company: DaVita

Location: St. Louis, MO

Posted Jan 24, 2025

DaVita is seeking a Patient Care Technician (PCT) for an outpatient dialysis center in Granite City, Illinois. This role offers an opportunity to start a career in healthcare with paid, extensive training. The PCT will provide direct patient care, monitor patients before, during, and after dialysis, and build relationships with patients. The position involves working flexible hours, including mornings, evenings, weekends, and holidays. DaVita offers comprehensive benefits, including medical, dental, vision, 401(k) match, paid time off, and more. No dialysis experience is required, and healthcare experience is a plus. The company is committed to diversity and belonging, and applications are accepted on an ongoing basis.

Account Manager III

Company: Thermo Fisher Scientific

Location: Kansas City, MO

Posted Jan 24, 2025

Thermo Fisher Scientific is seeking a Laboratory Consumables Representative for the Laboratory Products Division. The role involves selling state-of-the-art laboratory consumables solutions, meeting sales targets, and building strong relationships with clients. The ideal candidate should have a Bachelor's degree in Life Science, 5+ years of sales experience, and knowledge of diverse laboratory product applications. The company offers competitive compensation, benefits including healthcare, PTO, and retirement plans, and a dynamic company culture.

Senior Bioprocess Automation Engineer

Company: Thermo Fisher Scientific

Location: St. Louis, MO

Posted Jan 24, 2025

Thermo Fisher Scientific is seeking an experienced engineer for a role in St. Louis, MO or remotely with significant travel. The ideal candidate will design, develop, and support AI/ML workflows for data analysis and equipment automation, lead automation projects, and collaborate with global teams. Key requirements include a Bachelor's degree in a relevant technical field, 5+ years of engineering/automation experience, and expertise in AI/ML integration. Strong programming skills in JAVA, Python, and C++ are preferred, along with experience with automation platforms like Delta V, Allen Bradley, and Siemens. The role involves working in an R&D laboratory setting and implementing Industry 4.0 digital and software technologies in a bioprocessing environment.

Counsel, Security Solutions

Company: Mastercard

Location: O'Fallon, MO

Posted Jan 24, 2025

Outside Sales Professional

Company: Rentokil Terminix

Location: Kansas City, MO

Posted Jan 24, 2025

Frequently Asked Questions

What types of tech jobs are available in St. Louis, MO?
St. Louis offers roles from software engineering and data science to cybersecurity, DevOps, UI/UX design, AI/ML research, and product management. The city’s healthtech and fintech sectors demand specialists in electronic health records, blockchain, and regulatory tech, while logistics firms need supply‑chain analytics and IoT developers.
How do remote and on‑site trends look in St. Louis?
Many companies now support hybrid models, with on‑site work preferred for roles that require collaboration, such as product design or systems engineering. Pure remote positions are common in software development and data analysis. Companies like Enterprise and Vontel offer flexible schedules, but a 3‑day on‑site requirement is typical for senior engineering roles.
Who are the major employers in St. Louis?
Key employers include BJC HealthCare, Enterprise Holdings, Eli Lilly & Co., Vontel, City of St. Louis, and the St. Louis Science Center’s research labs. Additionally, the city’s startup ecosystem includes companies such as Glean, Tasty, and the Midtown tech incubator, all actively hiring tech talent.
What are salary expectations for tech roles in St. Louis?
Median base salary for software engineers in St. Louis is around $95,000, with senior roles reaching $120,000+. Data scientists average $98,000, while cybersecurity analysts earn $88,000. These figures exceed the national average for comparable roles, reflecting the city’s focus on high‑growth industries. Transparent listings on Job Transparency help you benchmark offers against local market rates.
What advice is there for relocating to St. Louis for tech work?
Plan your move by researching neighborhoods: Midtown and the Central West End offer vibrant tech scenes and affordable housing; the St. Louis Riverfront and Oakville provide quieter options with easy access to downtown. Use Job Transparency’s salary tool to confirm that offers cover living costs. When interviewing, ask about relocation packages, housing stipends, and the company’s remote policy. Finally, tap local networking groups such as the St. Louis Tech Council and meetups to accelerate integration.

Related Pages