Tech Jobs in St. Louis, MO

61,353 open positions · Updated daily

St. Louis is becoming a tech hub thanks to a blend of healthcare innovation, a strong manufacturing base, and a growing fintech scene. With 14,708 tech openings, the city offers a mix of high‑growth startups and established firms, all powered by a talent pool fed by universities such as Saint Louis University and Washington University.

Key sectors driving the market include healthtech—home to life‑science giants like BJC HealthCare and Eli Lilly—financial technology, logistics software, and data analytics. Companies like Enterprise Holdings, Vontel, and the City of St. Louis use cutting‑edge platforms to streamline operations, while startups in the Central West End and Midtown districts are hiring full‑stack developers, AI/ML engineers, and cybersecurity specialists.

While the cost of living in St. Louis remains 15% below the national average, median rent for a one‑bedroom apartment in Midtown is around $1,200 and the median home price sits near $225,000. Transparent salary listings let candidates evaluate whether a role’s pay aligns with local living expenses—ensuring you can afford the lifestyle you want without hidden surprises.

Pharmacy Technician

Company: CVS Health

Location: Fenton, MO

Posted Jan 23, 2025

Take your career to heights: join SSM Health as a Family Medicine Physician in South County

Company: SSM Health

Location: Saint Louis, Missouri

Posted Jan 23, 2025

SSM Health, a reputable healthcare provider based in St. Louis, MO, is seeking a Family Medicine Physician. The role involves providing comprehensive healthcare to patients of all ages, managing chronic diseases, and collaborating with a multidisciplinary team. Key responsibilities include diagnosing and treating ailments, conducting physical exams, and maintaining patient records. The ideal candidate should have a medical degree, board certification in Family Medicine, and a valid Missouri medical license. SSM Health offers a competitive benefits package, including health insurance, retirement plan, CME allowance, and PTO. SSM Health, with a legacy of over 150 years, is one of the largest Catholic not-for-profit integrated health systems in the Midwest, serving Missouri, Oklahoma, Illinois, and Wisconsin.

QC Scientist I

Company: Thermo Fisher Scientific

Location: St. Louis, MO

Posted Jan 23, 2025

Pharmacy Technician

Company: CVS Health

Location: Fenton, MO

Posted Jan 23, 2025

Solution Engineer - State & Local Government (Midwest)

Company: Esri

Location: St. Louis, MO

Posted Jan 23, 2025

Esri is seeking a GIS subject matter expert with 3+ years of experience in Esri technology. The role involves creating innovative GIS solutions, presenting and demonstrating Esri software, and building relationships with customers. The ideal candidate should be a subject matter expert in state and local government and ArcGIS, with understanding of IT contexts like hardware, storage, security, networking, web services, virtualization, and cloud computing. Strong presentation, interpersonal, and listening skills are required, along with the ability to travel domestically or internationally up to 25-50%. Esri offers competitive total rewards, including health and welfare benefits, 401(k) programs, and opportunities for personal and professional growth.

(USA) Optometrist Pre-Grad Intern - Walmart

Company: Walmart

Location: Ozark, MO

Posted Jan 23, 2025

The role involves supporting optical care and services to customers, including obtaining measurements, verifying prescriptions, and counseling. Clinical care is provided by diagnosing customers and managing treatment of visual problems. The position also involves maintaining the optical area, ensuring it aligns with company policies and standards, and maintaining a safe work environment. Merchandise presentation is crucial, involving stocking, rotating, and organizing products. The role requires selling optical products and services, assisting customers with purchasing decisions, and completing eyewear/contact lens orders. Leadership expectations include respect for the individual, acting with integrity, serving the customer, and striving for excellence. Walmart offers competitive pay, health benefits, financial benefits, and other perks like PTO, disability benefits, and Live Better U education program.

Assistant Plant Manager

Company: 48forty Solutions

Location: Springfield, MO

Posted Jan 23, 2025

Digital Portfolio Owner

Company: Edward Jones

Location: St. Louis, MO

Posted Jan 23, 2025

Edward Jones is seeking a senior leader to head its Digital Operational Enablement Portfolio. This role involves driving a five-year strategy to enhance user experience through automation, vendor partnerships, generative AI, and in-house development. The leader will establish goals, measure accountability, and align with senior leaders across the firm. They will also attract, develop, and lead a team of product managers, product owners, and business systems analysts. The position requires a bachelor's degree, preferably an advanced degree or certification in a relevant field, and at least 10 years of experience in a financial, economic, or analytical role. Financial services industry experience is preferred. The role offers a competitive compensation package and benefits, including health insurance, retirement plans, and flexible spending accounts.

Branch Office Administrator

Company: Edward Jones

Location: Leadwood Town, MO

Posted Jan 23, 2025

Frequently Asked Questions

What types of tech jobs are available in St. Louis, MO?
St. Louis offers roles from software engineering and data science to cybersecurity, DevOps, UI/UX design, AI/ML research, and product management. The city’s healthtech and fintech sectors demand specialists in electronic health records, blockchain, and regulatory tech, while logistics firms need supply‑chain analytics and IoT developers.
How do remote and on‑site trends look in St. Louis?
Many companies now support hybrid models, with on‑site work preferred for roles that require collaboration, such as product design or systems engineering. Pure remote positions are common in software development and data analysis. Companies like Enterprise and Vontel offer flexible schedules, but a 3‑day on‑site requirement is typical for senior engineering roles.
Who are the major employers in St. Louis?
Key employers include BJC HealthCare, Enterprise Holdings, Eli Lilly & Co., Vontel, City of St. Louis, and the St. Louis Science Center’s research labs. Additionally, the city’s startup ecosystem includes companies such as Glean, Tasty, and the Midtown tech incubator, all actively hiring tech talent.
What are salary expectations for tech roles in St. Louis?
Median base salary for software engineers in St. Louis is around $95,000, with senior roles reaching $120,000+. Data scientists average $98,000, while cybersecurity analysts earn $88,000. These figures exceed the national average for comparable roles, reflecting the city’s focus on high‑growth industries. Transparent listings on Job Transparency help you benchmark offers against local market rates.
What advice is there for relocating to St. Louis for tech work?
Plan your move by researching neighborhoods: Midtown and the Central West End offer vibrant tech scenes and affordable housing; the St. Louis Riverfront and Oakville provide quieter options with easy access to downtown. Use Job Transparency’s salary tool to confirm that offers cover living costs. When interviewing, ask about relocation packages, housing stipends, and the company’s remote policy. Finally, tap local networking groups such as the St. Louis Tech Council and meetups to accelerate integration.

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