Tech Jobs in St. Louis, MO

61,353 open positions · Updated daily

St. Louis is becoming a tech hub thanks to a blend of healthcare innovation, a strong manufacturing base, and a growing fintech scene. With 14,708 tech openings, the city offers a mix of high‑growth startups and established firms, all powered by a talent pool fed by universities such as Saint Louis University and Washington University.

Key sectors driving the market include healthtech—home to life‑science giants like BJC HealthCare and Eli Lilly—financial technology, logistics software, and data analytics. Companies like Enterprise Holdings, Vontel, and the City of St. Louis use cutting‑edge platforms to streamline operations, while startups in the Central West End and Midtown districts are hiring full‑stack developers, AI/ML engineers, and cybersecurity specialists.

While the cost of living in St. Louis remains 15% below the national average, median rent for a one‑bedroom apartment in Midtown is around $1,200 and the median home price sits near $225,000. Transparent salary listings let candidates evaluate whether a role’s pay aligns with local living expenses—ensuring you can afford the lifestyle you want without hidden surprises.

General Manager

Company: Aramark

Location: St. Louis, MO

Posted Jan 23, 2025

Lead Software Engineer

Company: Mastercard

Location: O'Fallon, MO

Posted Jan 23, 2025

Senior Banker

Company: Merrill

Location: Columbia, MO

Posted Jan 23, 2025

Automotive Claims Adjuster

Company: Protective

Location: Chesterfield, MO

Posted Jan 23, 2025

Insurance Agent (Base salary + Uncapped commissions)

Company: Comparion Insurance Agency

Location: Kansas City, MO

Posted Jan 23, 2025

Comparion Insurance Agency is seeking a Sales Agent for their Lee's Summit office. The role involves building and leveraging local networks and in-person relationships. Successful candidates will have a strong work ethic, be self-motivated, adaptable, coachable, results-oriented, and charismatic. The position offers uncapped pay, recognition, paid training, sales support, comprehensive benefits, and opportunities for career growth. Preferred qualifications include previous sales experience and a state insurance license in Property & Casualty and Life.

Director, BizOps

Company: Mastercard

Location: O'Fallon, MO

Posted Jan 23, 2025

Pharmacy Intern

Company: CVS Health

Location: Springfield, MO

Posted Jan 23, 2025

CVS Health is offering a 3rd year pharmacy intern position with opportunities for professional growth and making a significant impact in healthcare. The role involves ensuring patient safety, managing pharmacy operations, and delivering exceptional customer service. Interns will work under a licensed pharmacist, participating in patient care programs, and demonstrating empathy and compassion. The position requires strong communication skills, relevant work experience, and valid intern/technician licensure. Proficiency in Microsoft Office Suite is preferred.

Retail Print Sales Specialist

Company: Staples

Location: Columbia, MO

Posted Jan 23, 2025

Staples is hiring immediately for a Print Specialist position. The role involves providing exceptional customer service, producing professionally finished products, and collaborating in a team-oriented retail culture. The job offers flexible part-time hours, generous paid time off, career growth opportunities, and various benefits including associate discounts, 401(k) plan, dental and vision insurance. Essential skills include flexibility, attention to detail, basic computer skills, and the ability to work in a high-paced environment. Staples is an Equal Opportunity Employer.

Dist Suppt Pharmacist FT

Company: CVS Health

Location: Lee's Summit, MO

Posted Jan 23, 2025

Food Service Worker

Company: Sodexo

Location: O'Fallon, MO

Posted Jan 23, 2025

Visual Keyholder

Company: H&M

Location: St. Peters, MO

Posted Jan 23, 2025

The Visual Keyholder role at H&M involves creating an inspiring shopping environment, driving sales, and implementing the brand's visual identity. Key responsibilities include setting garment presentations, staying updated on fashion trends, ensuring excellent customer service, and maintaining store KPIs. The role requires strong fashion knowledge, customer service skills, and the ability to work in a fast-paced environment. H&M offers a dynamic work environment, growth opportunities, and a staff discount on all group brands.

Senior Software Engineer

Company: Mastercard

Location: O'Fallon, MO

Posted Jan 23, 2025

Mastercard, a global technology company in the payments sector, is seeking a Senior Software Engineer. The role involves manual testing, test data preparation, case execution, defect tracking, and participation in team prioritization discussions. The candidate should have experience in the complete testing life cycle, understanding of payment-based technologies, and exposure to multiple types of coding. Mastercard values inclusivity and offers competitive compensation, benefits, and opportunities for professional growth.

Frequently Asked Questions

What types of tech jobs are available in St. Louis, MO?
St. Louis offers roles from software engineering and data science to cybersecurity, DevOps, UI/UX design, AI/ML research, and product management. The city’s healthtech and fintech sectors demand specialists in electronic health records, blockchain, and regulatory tech, while logistics firms need supply‑chain analytics and IoT developers.
How do remote and on‑site trends look in St. Louis?
Many companies now support hybrid models, with on‑site work preferred for roles that require collaboration, such as product design or systems engineering. Pure remote positions are common in software development and data analysis. Companies like Enterprise and Vontel offer flexible schedules, but a 3‑day on‑site requirement is typical for senior engineering roles.
Who are the major employers in St. Louis?
Key employers include BJC HealthCare, Enterprise Holdings, Eli Lilly & Co., Vontel, City of St. Louis, and the St. Louis Science Center’s research labs. Additionally, the city’s startup ecosystem includes companies such as Glean, Tasty, and the Midtown tech incubator, all actively hiring tech talent.
What are salary expectations for tech roles in St. Louis?
Median base salary for software engineers in St. Louis is around $95,000, with senior roles reaching $120,000+. Data scientists average $98,000, while cybersecurity analysts earn $88,000. These figures exceed the national average for comparable roles, reflecting the city’s focus on high‑growth industries. Transparent listings on Job Transparency help you benchmark offers against local market rates.
What advice is there for relocating to St. Louis for tech work?
Plan your move by researching neighborhoods: Midtown and the Central West End offer vibrant tech scenes and affordable housing; the St. Louis Riverfront and Oakville provide quieter options with easy access to downtown. Use Job Transparency’s salary tool to confirm that offers cover living costs. When interviewing, ask about relocation packages, housing stipends, and the company’s remote policy. Finally, tap local networking groups such as the St. Louis Tech Council and meetups to accelerate integration.

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