Tech Jobs in St. Louis, MO

61,353 open positions · Updated daily

St. Louis is becoming a tech hub thanks to a blend of healthcare innovation, a strong manufacturing base, and a growing fintech scene. With 14,708 tech openings, the city offers a mix of high‑growth startups and established firms, all powered by a talent pool fed by universities such as Saint Louis University and Washington University.

Key sectors driving the market include healthtech—home to life‑science giants like BJC HealthCare and Eli Lilly—financial technology, logistics software, and data analytics. Companies like Enterprise Holdings, Vontel, and the City of St. Louis use cutting‑edge platforms to streamline operations, while startups in the Central West End and Midtown districts are hiring full‑stack developers, AI/ML engineers, and cybersecurity specialists.

While the cost of living in St. Louis remains 15% below the national average, median rent for a one‑bedroom apartment in Midtown is around $1,200 and the median home price sits near $225,000. Transparent salary listings let candidates evaluate whether a role’s pay aligns with local living expenses—ensuring you can afford the lifestyle you want without hidden surprises.

Shift Lead

Company: Walgreens

Location: Poplar Bluff, MO

Posted Jan 23, 2025

Pharmacy Manager

Company: Walgreens

Location: Maryland Heights, MO

Posted Jan 23, 2025

Customer Service Associate

Company: Walgreens

Location: St. Louis, MO

Posted Jan 23, 2025

Maintenance Tech

Company: Sysco

Location: St. Cloud, MN

Posted Jan 23, 2025

Sysco Western Minnesota, Inc. is seeking a full-time Warehouse Maintenance Technician. The role involves maintaining warehouse equipment in safe, efficient condition, performing fire and sprinkler inspections, and handling light maintenance on trailers. The job requires a high school diploma or equivalent, 10 years of technical experience in mechanics and electronics is preferred. Physical demands include lifting up to 75 lbs occasionally and excellent hand-eye coordination. The position offers a pay range of $27 per hour plus, DOE, and the opportunity to work for a global leader in foodservice distribution.

Customer Service Associate

Company: Walgreens

Location: St. Petersburg, FL

Posted Jan 23, 2025

The text describes a job role that involves delivering a distinctive and delightful customer experience. The responsibilities include engaging customers, resolving issues, and providing efficient checkout service. The role also involves maintaining store cleanliness, implementing asset protection procedures, and ensuring compliance with regulated product laws. The job requires fluency in English and a flexible schedule, including evenings and weekends. Preferred qualifications include prior retail experience and familiarity with Walgreens.

Pharmacy Technician / Pharm Tech Apprenticeship

Company: Walgreens

Location: Poplar Bluff, MO

Posted Jan 23, 2025

Walgreens is transforming its pharmacy technician roles to a more patient-centric environment. As a Walgreens Pharmacy Technician or Apprentice, you'll interact with customers, develop strong patient relationships, and have access to the latest technology to grow your career. Walgreens offers an 'earn while you learn' Pharmacy Technician Training Program, recognized by ASHP and the Department of Labor, which guides you towards becoming a PTCB Certified Pharmacy Technician. The role involves assisting pharmacists, using pharmacy systems, maintaining customer service, and participating in inventory management. Fluency in English, good math and computer skills, and preferably prior retail or Walgreens experience are required. PTCB certification is preferred but not mandatory. The role offers training, personal development opportunities, and potential for eight college credit hours through the Walgreens pharmacy technician apprenticeship program.

Certified Pharmacy Technician, Micro-Fulfillment Center

Company: Walgreens

Location: Independence, MO

Posted Jan 23, 2025

The job posting is for a Certified Pharmacy Technician (CPhT) position at Walgreens Boots Alliance. The role involves data entry, patient registration, and resolution of third-party rejects. Key responsibilities include processing new patient registrations, handling prescription requests, troubleshooting missing information, and operating automated machinery for medication sorting and packaging. The position requires basic PC and keyboarding skills, flexibility for various shifts, and willingness to lift up to 50 pounds. Preferred qualifications include pharmacy technician experience and advanced keyboarding skills. The salary range is $18.5 - $23.3 per hour.

Emerging Store Manager

Company: Walgreens

Location: Fenton, MO

Posted Jan 23, 2025

Frequently Asked Questions

What types of tech jobs are available in St. Louis, MO?
St. Louis offers roles from software engineering and data science to cybersecurity, DevOps, UI/UX design, AI/ML research, and product management. The city’s healthtech and fintech sectors demand specialists in electronic health records, blockchain, and regulatory tech, while logistics firms need supply‑chain analytics and IoT developers.
How do remote and on‑site trends look in St. Louis?
Many companies now support hybrid models, with on‑site work preferred for roles that require collaboration, such as product design or systems engineering. Pure remote positions are common in software development and data analysis. Companies like Enterprise and Vontel offer flexible schedules, but a 3‑day on‑site requirement is typical for senior engineering roles.
Who are the major employers in St. Louis?
Key employers include BJC HealthCare, Enterprise Holdings, Eli Lilly & Co., Vontel, City of St. Louis, and the St. Louis Science Center’s research labs. Additionally, the city’s startup ecosystem includes companies such as Glean, Tasty, and the Midtown tech incubator, all actively hiring tech talent.
What are salary expectations for tech roles in St. Louis?
Median base salary for software engineers in St. Louis is around $95,000, with senior roles reaching $120,000+. Data scientists average $98,000, while cybersecurity analysts earn $88,000. These figures exceed the national average for comparable roles, reflecting the city’s focus on high‑growth industries. Transparent listings on Job Transparency help you benchmark offers against local market rates.
What advice is there for relocating to St. Louis for tech work?
Plan your move by researching neighborhoods: Midtown and the Central West End offer vibrant tech scenes and affordable housing; the St. Louis Riverfront and Oakville provide quieter options with easy access to downtown. Use Job Transparency’s salary tool to confirm that offers cover living costs. When interviewing, ask about relocation packages, housing stipends, and the company’s remote policy. Finally, tap local networking groups such as the St. Louis Tech Council and meetups to accelerate integration.

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