Tech Jobs in St. Louis, MO

61,353 open positions · Updated daily

St. Louis is becoming a tech hub thanks to a blend of healthcare innovation, a strong manufacturing base, and a growing fintech scene. With 14,708 tech openings, the city offers a mix of high‑growth startups and established firms, all powered by a talent pool fed by universities such as Saint Louis University and Washington University.

Key sectors driving the market include healthtech—home to life‑science giants like BJC HealthCare and Eli Lilly—financial technology, logistics software, and data analytics. Companies like Enterprise Holdings, Vontel, and the City of St. Louis use cutting‑edge platforms to streamline operations, while startups in the Central West End and Midtown districts are hiring full‑stack developers, AI/ML engineers, and cybersecurity specialists.

While the cost of living in St. Louis remains 15% below the national average, median rent for a one‑bedroom apartment in Midtown is around $1,200 and the median home price sits near $225,000. Transparent salary listings let candidates evaluate whether a role’s pay aligns with local living expenses—ensuring you can afford the lifestyle you want without hidden surprises.

Bioenvironmental Engineer

Company:

Location: Florissant, MO

Posted Jan 23, 2025

The text discusses the Air Force's commitment to environmental safety, emphasizing the role of Bioenvironmental Engineers in identifying and mitigating potential hazards. These specialists, through engineering and scientific principles, ensure the health and safety of Airmen and their families worldwide. The text also outlines the requirements for joining the Air Force, including a Bachelor of Science in engineering from an ABET-accredited institution, completion of specific courses, and age restrictions.

Physician Assistant (PA-C)

Company:

Location: Raymore, MO

Posted Jan 23, 2025

Physician Assistant (PA-C)

Company:

Location: Lee's Summit, MO

Posted Jan 23, 2025

DispatchHealth is hiring Nurse Practitioners and Physician Assistants with acute care experience for their growing team in Kansas City. The role involves delivering comprehensive health assessments, diagnosis, treatment, and outcome management for patients of all ages in their homes. The company offers flexible schedules, competitive compensation, continued education, growth opportunities, on-site training, and a company vehicle. Providers appreciate the high-quality care they can provide, the value of the delivery model, and patient appreciation.

Brand Activation Manager

Company:

Location: Columbia, MO

Posted Jan 23, 2025

Anheuser-Busch is seeking a dynamic Brand Activation Manager for the NUTRL brand in Columbia, MO. The role involves developing and executing activation strategies, managing a team of Brand Ambassadors, and overseeing sampling events. The ideal candidate should have 2+ years of beverage industry experience, strong leadership skills, and proficiency in Excel and PPT. The company offers a competitive salary, professional development opportunities, and potential for career advancement.

Nurse Manager - $10k sign on

Company:

Location: Chesterfield, MO

Posted Jan 23, 2025

Bioenvironmental Engineer

Company:

Location: Hannibal, MO

Posted Jan 23, 2025

Security Officer

Company:

Location: O'Fallon, MO

Posted Jan 23, 2025

Physician Assistant (PA-C)

Company:

Location: Independence, MO

Posted Jan 23, 2025

Furniture Retail Sales Associate

Company:

Location: Springfield, MO

Posted Jan 23, 2025

Environmental Services Department Manager

Company:

Location: St. Albans City, VT

Posted Jan 23, 2025

Healthcare Services Group (HCSG) is a reputable company with over 45 years of experience in managing essential services in the healthcare sector. They are recognized as one of America's Most Trustworthy Companies, valuing integrity, collaboration, empowerment, passion, and perseverance. HCSG offers comprehensive benefits, including telemedicine, medical, dental, vision plans, and employee assistance programs. They prioritize employee safety and well-being, providing personal protective equipment and COVID-19 vaccination requirements. The Department Manager role involves supervising housekeeping, laundry, and floor care staff, ensuring quality control, and maintaining records. HCSG is committed to fostering a fulfilling work environment, offering growth opportunities, and promoting diversity and inclusion.

Refinery Engineer Manager

Company:

Location: St. Marys, GA

Posted Jan 23, 2025

Synergy, a Clean Harbors company, is seeking a Refinery Engineer Manager for their Kingsland GA team. The role involves overseeing the maintenance department, managing projects, and budget costs. The position is 30-40% plant-based and 60-70% office-based. Synergy prioritizes health and safety, offering competitive wages, comprehensive health benefits, and opportunities for career growth. The ideal candidate should have a Bachelor's degree in Industrial, Mechanical, or Chemical Engineering, 5-7 years of engineering experience, and 3 years of project management experience. Knowledge of CAD programs, process instrumentation, and refinery experience is preferred. Synergy is a world-class environmental service organization with a commitment to keeping North American businesses green.

Physician Assistant (PA-C)

Company:

Location: Independence, MO

Posted Jan 23, 2025

Frequently Asked Questions

What types of tech jobs are available in St. Louis, MO?
St. Louis offers roles from software engineering and data science to cybersecurity, DevOps, UI/UX design, AI/ML research, and product management. The city’s healthtech and fintech sectors demand specialists in electronic health records, blockchain, and regulatory tech, while logistics firms need supply‑chain analytics and IoT developers.
How do remote and on‑site trends look in St. Louis?
Many companies now support hybrid models, with on‑site work preferred for roles that require collaboration, such as product design or systems engineering. Pure remote positions are common in software development and data analysis. Companies like Enterprise and Vontel offer flexible schedules, but a 3‑day on‑site requirement is typical for senior engineering roles.
Who are the major employers in St. Louis?
Key employers include BJC HealthCare, Enterprise Holdings, Eli Lilly & Co., Vontel, City of St. Louis, and the St. Louis Science Center’s research labs. Additionally, the city’s startup ecosystem includes companies such as Glean, Tasty, and the Midtown tech incubator, all actively hiring tech talent.
What are salary expectations for tech roles in St. Louis?
Median base salary for software engineers in St. Louis is around $95,000, with senior roles reaching $120,000+. Data scientists average $98,000, while cybersecurity analysts earn $88,000. These figures exceed the national average for comparable roles, reflecting the city’s focus on high‑growth industries. Transparent listings on Job Transparency help you benchmark offers against local market rates.
What advice is there for relocating to St. Louis for tech work?
Plan your move by researching neighborhoods: Midtown and the Central West End offer vibrant tech scenes and affordable housing; the St. Louis Riverfront and Oakville provide quieter options with easy access to downtown. Use Job Transparency’s salary tool to confirm that offers cover living costs. When interviewing, ask about relocation packages, housing stipends, and the company’s remote policy. Finally, tap local networking groups such as the St. Louis Tech Council and meetups to accelerate integration.

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