Tech Jobs in St. Louis, MO

61,353 open positions · Updated daily

St. Louis is becoming a tech hub thanks to a blend of healthcare innovation, a strong manufacturing base, and a growing fintech scene. With 14,708 tech openings, the city offers a mix of high‑growth startups and established firms, all powered by a talent pool fed by universities such as Saint Louis University and Washington University.

Key sectors driving the market include healthtech—home to life‑science giants like BJC HealthCare and Eli Lilly—financial technology, logistics software, and data analytics. Companies like Enterprise Holdings, Vontel, and the City of St. Louis use cutting‑edge platforms to streamline operations, while startups in the Central West End and Midtown districts are hiring full‑stack developers, AI/ML engineers, and cybersecurity specialists.

While the cost of living in St. Louis remains 15% below the national average, median rent for a one‑bedroom apartment in Midtown is around $1,200 and the median home price sits near $225,000. Transparent salary listings let candidates evaluate whether a role’s pay aligns with local living expenses—ensuring you can afford the lifestyle you want without hidden surprises.

Maternity RN Case Manager - Remote - Greater St Louis Area, MO

Company: UnitedHealth Group

Location: O'Fallon, MO

Posted Jan 22, 2025

UnitedHealthcare is offering a rewarding role in the Greater St Louis Area, MO, for a qualified RN with OB or NICU experience. The position involves providing evidence-based education for healthy pregnancy outcomes, coordinating care for high-risk maternity members, and making outbound calls to assess members' health status. The successful candidate will also identify gaps in treatment plans, educate members on disease processes, and encourage healthy lifestyle changes. This role requires proficiency in Microsoft Office Suite, strong communication skills, and the ability to work independently and as part of a team. UnitedHealthcare is committed to creating a positive impact on healthcare, promoting healthier communities, and removing barriers to quality care.

Store Associate

Company: CVS Health

Location: St. Louis, MO

Posted Jan 23, 2025

CVS Health is seeking Retail Store Associates to join their team, emphasizing a human-centric approach to healthcare. The role involves providing excellent customer service, maintaining the sales floor, supporting store activities, and assisting in the pharmacy. The company offers competitive pay, comprehensive benefits, and opportunities for career growth. No prior retail experience is required, but a high school diploma is preferred.

Engineer III

Company: Edward Jones

Location: St. Louis, MO

Posted Jan 23, 2025

Edward Jones is currently hiring for an Engineer III position in their Technology Learning team. The role involves utilizing technical leadership in Java Development and Oracle Database Interaction to deliver high-quality software solutions. Key responsibilities include designing, developing, and maintaining software applications, collaborating on system architecture, ensuring code quality, mentoring junior engineers, troubleshooting complex technical issues, and optimizing application performance. The company offers a comprehensive benefits package, including medical, dental, vision, disability, life insurance, retirement plans, and flexible spending accounts. Candidates should have a Bachelor's degree, 5+ years of software development experience, proficiency in Java Spring framework, Oracle SQL/PLSQL, Maven, Git, microservices, Restful API development, Microsoft Azure, and DevOps practices. Preference is given to candidates living within commutable distance from Tempe, AZ and St. Louis, MO home office locations, who can work in the office three days a week.

Sr Site Specialist

Company: Thermo Fisher Scientific

Location: St. Louis, MO

Posted Jan 22, 2025

Phlebotomist

Company: Labcorp

Location: O'Fallon, MO

Posted Jan 23, 2025

Labcorp is seeking a Phlebotomist for a role in either a Patient Service Center or Client office. The position involves providing exceptional customer service, performing skilled specimen collections, and maintaining patient information logs. The company offers comprehensive benefits, opportunities for growth, and a positive work environment. The ideal candidate should have phlebotomy certification, strong communication skills, and the ability to work independently or in a team.

Marketing Manager (Enterprise Fleet Management)

Company: Enterprise Mobility

Location: St. Louis, MO

Posted Jan 23, 2025

Enterprise Mobility is seeking a Marketing Manager (EFM) to grow the business by leading marketing efforts, including planning and implementing insights-driven campaigns. The role involves balancing the needs of an established business and exploring new opportunities to drive key marketing objectives. Responsibilities include creating and optimizing marketing strategies, collaborating with internal teams, and managing marketing specialists. The position offers a competitive benefits package and is located at the Corporate Headquarters in Clayton, MO with a hybrid schedule.

Automotive Technician Apprentice (Night Shift) ($2,500 Sign-On Bonus)

Company: CarMax

Location: St. Peters, MO

Posted Jan 23, 2025

CarMax, a leading used car retailer, is hiring Automotive Technicians with a $2,500 sign-on bonus for external candidates. The role involves inspecting, reconditioning, and repairing vehicles to ensure customer safety and satisfaction. Technicians work in a fast-paced environment, solving technical problems, and meeting deadlines. CarMax offers a range of benefits including paid time off, medical/dental coverage, 401k with company match, vehicle discount, tuition reimbursement, and more. The company values continuous learning and development, providing training and support for acquiring new skillsets and accreditations.

Internal IT and Systems Adminstrator

Company: LightEdge Solutions

Location: Kansas City, MO

Posted Jan 23, 2025

LightEdge is hiring an Internal IT and Systems Administrator for their Kansas City office. The role involves providing technical support, managing security software, maintaining employee equipment, and participating in regulatory compliance audits. The ideal candidate should have an associate degree in IT or equivalent experience, with 1-3 years of experience in server storage network environments. Strong communication skills and a willingness to learn are essential. The role offers opportunities for professional growth in a rapidly expanding company.

Sr. Change Management Consultant

Company: Esri

Location: St. Louis, MO

Posted Jan 22, 2025

Frequently Asked Questions

What types of tech jobs are available in St. Louis, MO?
St. Louis offers roles from software engineering and data science to cybersecurity, DevOps, UI/UX design, AI/ML research, and product management. The city’s healthtech and fintech sectors demand specialists in electronic health records, blockchain, and regulatory tech, while logistics firms need supply‑chain analytics and IoT developers.
How do remote and on‑site trends look in St. Louis?
Many companies now support hybrid models, with on‑site work preferred for roles that require collaboration, such as product design or systems engineering. Pure remote positions are common in software development and data analysis. Companies like Enterprise and Vontel offer flexible schedules, but a 3‑day on‑site requirement is typical for senior engineering roles.
Who are the major employers in St. Louis?
Key employers include BJC HealthCare, Enterprise Holdings, Eli Lilly & Co., Vontel, City of St. Louis, and the St. Louis Science Center’s research labs. Additionally, the city’s startup ecosystem includes companies such as Glean, Tasty, and the Midtown tech incubator, all actively hiring tech talent.
What are salary expectations for tech roles in St. Louis?
Median base salary for software engineers in St. Louis is around $95,000, with senior roles reaching $120,000+. Data scientists average $98,000, while cybersecurity analysts earn $88,000. These figures exceed the national average for comparable roles, reflecting the city’s focus on high‑growth industries. Transparent listings on Job Transparency help you benchmark offers against local market rates.
What advice is there for relocating to St. Louis for tech work?
Plan your move by researching neighborhoods: Midtown and the Central West End offer vibrant tech scenes and affordable housing; the St. Louis Riverfront and Oakville provide quieter options with easy access to downtown. Use Job Transparency’s salary tool to confirm that offers cover living costs. When interviewing, ask about relocation packages, housing stipends, and the company’s remote policy. Finally, tap local networking groups such as the St. Louis Tech Council and meetups to accelerate integration.

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