Remote-First Company Jobs in USA

456,353 open positions · Updated daily

Looking for Remote-First Company jobs in USA? Browse our curated listings with transparent salary information to find the perfect Remote-First Company position in the USA area.

Staff Data Scientist

Company: Platform Science

Location: USA

Posted Dec 07, 2025

Platform Science is an open IoT platform founded in 2015 that partners with fleets, application developers, vehicle manufacturers, and equipment providers in the transportation industry. They are seeking a Staff Data Scientist to process large amounts of raw data into strategic insights and lead the evaluation, design, and implementation of machine learning models and statistical analyses to support key business objectives.

Senior Platform Engineer - ML Data Systems

Company: Khan Academy

Location: USA

Posted Dec 07, 2025

Khan Academy is a nonprofit organization with a mission to provide free, world-class education to anyone, anywhere. They offer high-quality learning content and practice for PreK-12th grade and early college core academic subjects, focusing on math and science. The company values diversity, equity, inclusion, and belonging, and is committed to improving learning outcomes for students worldwide, especially those in historically under-resourced communities. They are looking for an ML Data Engineer to evolve their evaluation dataset tools to meet the growing platform needs of AI-based tutoring.

Senior/Staff Content Designer

Company: Grow Therapy

Location: USA

Posted Dec 07, 2025

The job posting is for a Senior Staff Content Designer role at Grow Therapy. The role involves crafting clear, inclusive, and trustworthy product experiences across client and provider products. The ideal candidate will have 6+ years of content design/UX writing experience, a strong portfolio, and expertise in UX writing, content strategy, and systems thinking. The role requires collaboration with cross-functional teams, including product design, research, and operations, to define messaging, craft value propositions, and shape content systems. The position offers a competitive base compensation and can be hybrid or fully remote.

Principal Software Engineer - Payroll

Company: Gusto, Inc.

Location: USA

Posted Dec 07, 2025

The role is for a Principal Engineer to lead the development of Gusto's flagship Payroll product. The position involves designing, building, and scaling backend systems, collaborating with cross-functional teams, and mentoring engineers. The ideal candidate has 15+ years of experience, expertise in building resilient systems, and a collaborative mindset.

Staff Data Scientist - Engagement Ecosystem

Company: Pinterest

Location: USA

Posted Dec 07, 2025

Pinterest is seeking a Staff Data Scientist to shape the future of their engagement ecosystem. The role involves developing a deep understanding of the platform, leading projects on tradeoffs between organic engagement and advertising, and designing robust ML frameworks. The ideal candidate will have 10+ years of experience in data environments, expertise in machine learning and causal inference, and strong communication skills.

Senior Frontend Web Engineer - Compliance Engineer

Company: Reddit

Location: USA

Posted Dec 07, 2025

Reddit is a platform that brings community and belonging to people worldwide through various interest-based communities. The company is launching a Compliance Engineering team to ensure their platforms meet evolving regulatory requirements and maintain trust. The role involves shaping the future of Reddit, partnering with teams, and leading initiatives critical to the business and platform integrity.

Lead AI Engineer

Company: Upwork

Location: USA

Posted Dec 07, 2025

Upwork is a global work marketplace connecting businesses with skilled independent talent. The company offers AI-powered solutions and enables companies to scale, innovate, and build agile teams. The job description is for a Lead AI Engineer position on the Data Platform & Services team, focusing on building AI-powered systems for data engineering, analytics, and product evolution.

Demo Strategy & Effectiveness Manager

Company: Figma

Location: USA

Posted Dec 07, 2025

The job posting is for a Demo Strategy & Effectiveness Manager at Figma, responsible for designing and enabling world-class demo experiences for the company's products. The role involves collaborating with various teams, staying up-to-date with new features, and training the field team. Figma offers a competitive compensation package and values continuous learning and growth.

Senior Software Engineer - Developer Tools, Poe

Company: Quora

Location: USA

Posted Dec 07, 2025

Quora seeks engineers to join their remote team, focusing on Poe's AI platform. The role involves building tools for developers, with a culture of collaboration and innovation. Benefits include competitive pay, remote work, and equity.

Senior/ Staff ML Engineer - Recommendations Systems

Company: Grow Therapy

Location: USA

Posted Dec 07, 2025

The company is seeking a machine learning engineer with experience in search and personalization to design, develop, and deploy a scalable search ranking algorithm. The role involves collaborating with data scientists, implementing machine learning models, and working cross-functionally with various teams.

Software Engineer - Lua

Company: Vercel

Location: USA

Posted Dec 07, 2025

The role involves scaling CDN services, collaborating with teams, and optimizing performance. Requirements include Lua expertise and HTTP knowledge. Benefits include competitive pay, healthcare, and flexible work arrangements.

Staff, Product Manager - AI/ML PLatform - Enterprise AI

Company: Twilio

Location: USA

Posted Dec 07, 2025

Twilio is seeking a Staff Product Manager for their Enterprise AI team to lead the development of AI platform capabilities. The role involves defining the product roadmap, building AI reasoning engines, and creating no-code experiences for internal and external teams. The ideal candidate has 7+ years of product management experience, deep knowledge of NLP and LLMs, and experience with enterprise AI platforms.

Frequently Asked Questions

What are typical salary ranges by seniority for Remote-First roles?
Junior Engineer: $70k‑$90k; Mid‑Level: $90k‑$120k; Senior Engineer: $120k‑$160k; Lead Engineer: $160k‑$200k; Principal Engineer: $200k‑$250k. Remote‑First companies often add a 5–10% cost‑of‑living adjustment for high‑cost regions, making these bands competitive globally.
What skills and certifications are required for Remote-First positions?
Technical: AWS Certified Solutions Architect, Google Cloud Professional Data Engineer, Terraform Associate, Docker Certified Associate, Kubernetes Administrator, React, Node.js, Python, Go. Soft: asynchronous communication, remote collaboration with Slack/Zoom, documentation in Confluence, and experience with GitHub Actions for CI/CD.
Is remote work fully available for all positions?
All listed roles are 100% remote with no on‑site requirement. Companies provide a 24‑hour coverage model, allowing team members in different time zones to overlap for core meetings and support windows.
What career progression paths exist in Remote-First companies?
Typical path: Junior → Mid → Senior → Lead → Technical Manager → VP. Promotion criteria include delivery quality, cross‑team mentorship, contribution to open‑source projects, and participation in internal learning hubs like remote‑first bootcamps.
What industry trends affect Remote-First companies today?
AI‑driven collaboration tools, outcome‑based performance metrics, distributed DevOps practices, emphasis on continuous learning, and remote‑first security frameworks (Zero Trust, VPNless access) are shaping the landscape. Companies are investing in these areas to reduce latency, increase resilience, and attract top talent.

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