Senior Scientist

Company Information

Legend Biotech is a global biotechnology company dedicated to treating, and one day curing, life-threatening diseases. Headquartered in Somerset, New Jersey, we are developing advanced cell therapies across a diverse array of technology platforms, including autologous and allogenic chimeric antigen receptor T-cell and natural killer (NK) cell-based immunotherapy. 

Legend Biotech entered into a global collaboration agreement with Janssen, one of the pharmaceutical companies of Johnson & Johnson, to jointly develop and commercialize ciltacabtagene autolecuel (cilta-cel) in 2017. Our strategic partnership is designed to combine the strengths and expertise of both companies to advance the promise of an immunotherapy in the treatment of multiple myeloma.

Legend Biotech is seeking Senior Scientist as part of the 

Research and Early Development team based in Piscataway, NJ. 

Role Overview

Legend Biotech USA, Inc. is seeking an experienced senior in vivo pharmacologist to join our in vivo pharmacology team responsible for conducting in vivo studies with mice and NHP to support pipeline development. This position will report directly to the Director of In vivo Pharmacology. The successful candidate should possess extensive knowledge and hands-on experience in conducting in vivo Pharmacology studies, especially in conducting cell-therapy based studies. The candidate should have knowledge and research experience in immunology, cancer biology and molecular biology, have comprehensive understanding of T/NK cell therapy and have expertise in immune cell profiling and function assay. The candidate needs to demonstrate the ability of delivering scientific results with integrity and meeting timeline, to show the value of collaboration and teamwork, and to provide strategy, expertise, and guidance in a fast-paced environment.

Key Responsibilities  

•  Conduct in vivo studies with mice and NHP; Interact with CROs for in vivo study related activities
• Interact with research teams for collaboration
• Process and analysis of tumor samples and tissues from mice and NHP
• Analyze, summary, review and present data
• Participate in assay development and qualification
• Maintain good documentation in ELN, paper notebook and log books.
  
• Perform additional exploratory and investigational studies with various techniques

•  Ph.D. or Master degree in biological sciences (Immunology, cell biology and cancer biology) or related area is required
  
• Extensive hands-on in vivo study experience is required (5 years. Expertise in various injection, bleeding, tissue collection and processing).
• Extensive experience in execution of cell-based and multi-color flow cytometry methods required.
• Prior experience in CAR-T/NK cell therapy development preferred.
• Strong critical thinking and problem-solving skills
• Sense of ownership and integrity of their work.
• A demonstrated ability to work as part of a team
  
• Demonstrated organizational skills including but not limited to attention to detail and multitasking
• Biotech or pharmaceutical industry experience is preferred but not required.

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Legend Biotech is a proud equal opportunity/affirmative action employer committed to attracting, retaining, and maximizing the performance of a diverse and inclusive workforce. It is Legend’s policy to ensure equal employment opportunity without discrimination or harassment based on race, color, religion, sex (including pregnancy, childbirth, or related medical conditions), sexual orientation, gender identity or expression, age, disability, national origin, marital or domestic/civil partnership status, genetic information, citizenship status, uniformed service member or veteran status, or any other characteristic protected by law.

Legend Biotech maintains a drug-free workplace.