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Voyager Prospects - Submit for future opportunities
Company: Voyager Therapeutics
Location: Cambridge
Posted Aug 05, 2023
Are you interested in joining Voyager Therapeutics but don't see a role that fits your background? Please submit your resume here and if we have a future opportunity, we will contact you.
IT Network Engineer
Company: Shape Therapeutics
Location: Seattle, WA
Posted Aug 04, 2023
We welcome individuals from all backgrounds who possess experience in information systems, information technology, and engineering. What You’ll DoDesign, implement, maintain, and monitor the corporate network and other data communication systems to ensure network connectivity throughout the organization, across multiple sites.Manage and expand network interconnections, network co-location sites and points of presence (POPs).Monitor and improve network performance and reliability based upon system performance metrics, including capacity planning, failure detection and remediation. Proactively identify and resolve issues to ensure optimal network operation and performance.Configure and install various network devices, including routers, switches, firewalls, load balancers, and wireless access points.Collaborate with internal teams to gather network requirements and design security-first, right-sized, scalable solutions that address business needs.Implement and maintain network security measures, including firewalls, intrusion detection systems, and virtual private networks (VPNs), to protect the organization's data, people, and systems.Collaborate with cloud team to manage and improve cloud (AWS) connectivity, security posture, and user management.Perform network capacity planning and recommend upgrades or enhancements to ensure availability, scalability, and performance.Troubleshoot end-to-end connectivity problems, including troubleshooting of the client and server machines when needed, to provide timely resolution of network-related incidents.Conduct regular network performance testing and analysis to identify areas for improvement and optimize network performance.Document network configurations, procedures, and troubleshooting steps to maintain an up-to-date network infrastructure knowledge base.Stay up to date with emerging technologies and industry trends in networking and make recommendations for incorporating new technologies into the organization's network infrastructure.Partner with 3rd party and IT vendors to further grow and mature IT operations.What you BringBachelor's degree (or equivalent experience) in Information Systems, Computer Science, Computer Engineering, Information Security, or similar technical or engineering experience in a relevant field or discipline.Minimum of 3+ years of professional experience with deploying enterprise network solutions, or cloud or web-scale networks.Proficiency and experience with two or more of; Palo Alto Networks firewalls (including Panorama), Cisco route/switch/wireless, Cisco Meraki switch/wireless, and Bigleaf Networks, is highly preferred.Experience configuring and operating network routing protocols including BGP and OSPF.Experience with two or more of; macOS, Windows 10/11, Windows Server, and/or Linux, is preferred.Experience navigating AWS networking preferred.Experience with AWS identity (IAM/SSO) and security services is a bonus.Compensation & BenefitsShapeTX offers a robust benefits package, including but not limited to: Medical, Dental and Vision coverage for employees and their eligible dependents. In addition, this position will build processes and systems, identify business opportunities, collaborate with cross-functional teams, scale up IT Infrastructure, and maintain our cybersecurity posture. We are dedicated to applying generative AI to revolutionize how gene editing, delivery, expression, and manufacturing are done for gene therapy. We are proud to offer a competitive paid parental leave benefit, an annual employee stipend for employees to use however they choose, a Flex Paid Time Off program (allowing flexible PTO for vacation, sick leave, and other purposes) and Company paid Long Term Disability. Employees are eligible to enroll in our Company’s voluntary 401k plan, voluntary Life/AD&D and Voluntary FSA’s.The salary range for this role is $96,000-$144,000. not only through our science, but also through our commitment to foster an inclusive environment that supports diverse perspectives and experiences. Additional compensation may include annual target bonus and/or sign-on bonus, equity grant and relocation bonus.We aspire to Shape Life! We believe in the power of diverse perspectives to drive innovation in gene therapy and are committed to creating an environment where integrity, patient impact, and personal growth are valued. Through diversity of thought, scientific knowledge, professional rigor and focus we are merging cutting-edge science with extensive drug development expertise to unlock cures to many debilitating diseases.Shape Therapeutics is headquartered in Seattle, Washington with a satellite site in Boston, Massachusetts. The hired applicant's placement within the range is based on qualifications and professional experience.
Product Manager
Company: Click Therapeutics
Location: New York City, NY
Posted Aug 04, 2023
Experience working with technologies including, but not limited to, ReactNative, Node.js, AWS. Technical leadership, project management, analytical problem solving, business analysis, and troubleshooting skills. Click Therapeutics will conduct interviews face-to-face over Zoom. Employment applicants requiring immigration sponsorship must disclose, when initial application for employment is made, whether or not they are legally authorized to work for Click Therapeutics in the U.S. and, if so, whether that authorization permits them to work in the job they seek. Background or previous experience in neuroscience, psychiatry, psychology, behavior change, digital health or a related field. Experience conducting clinical research. All job postings will be listed on the Click Therapeutics official career page. Competitive Salary with Annual Review | Annual Performance-Based Cash Bonus | Stock options | 5% 401(k) matching | Comprehensive Medical Benefits | Dental | Vision | Voluntary Benefits | Unlimited PTO | Uber One | Nectar Rewards | One Medical | Fertility Support | Gym Pass | Citi Bike | Professional Development Stipend | Weekly Grubhub Lunches | Generous Paid Parental Leave | Industrious Workspaces | Commuter Subsidies | Choice of Mac or Windows | Sponsored Company Events | Office Snacks and Beverages | Much More...Equal Employment Opportunity:Click Therapeutics is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. The final base salary will be dependent upon skills, experience and location. If someone contacts you about a job or position that is not listed on the official career page, please contact the Click Therapeutics recruitment team at the contact information below.
Senior Statistical Programmer
Company: Arcturus Therapeutics
Location: San Diego, CA
Posted Aug 04, 2023
For a deeper dive into our company and corporate culture visit www.ArcturusRx.com Arcturus is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. EDUCATION Bachelor's degree in Statistics, Computer Science, Mathematics, or related technical discipline. SDTM, ADaM specifications)Generate SDTM domains, ADaM datasets, and Define.xml or Define.pdf files.Strong knowledge of SAS functionalities (including ODS, SQL, MACRO, STAT, GRAPH, and ACCESS) and experience with MS Office are required. WHAT WE OFFER At Arcturus Therapeutics, our Total Rewards offerings also include inclusive market-leading benefits to meet our employees wherever they are in their career, financial, family, and wellbeing journey while providing flexibility and resources to support their growth and aspirations. Some roles may also be eligible for overtime pay, in accordance with federal and state requirements. The final salary offered to a successful candidate will be dependent on several factors that may include but are not limited to the type and length of experience within the job, type and length of experience within the industry, education, etc. Familiarity or experience with R Software is a plus.Perform quality control for SAS programs and other study documents (e.g., presentations and reports).Assist in programming, testing, and documenting SAS global utility programs and tools in accordance with standards and validation procedures.Generate analysis datasets, tables, figures, and listings to support the statistical analysis of clinical trials .data in support of regulatory submissions and publications under supervision of biostatisticians.Provide statistical programming support to supplemental or exploratory analyses for regulatory agencies or any other internal and external ad-hoc requests.Maintain complete and auditable documentation of all programming activities.Review CRFs, edit check specifications, and table mock-ups.Participates in monitoring CRO activities and reviewing CRO deliverables, as necessary.Other duties as assigned.Clear understanding of the drug development process, submission-related activities and regulatory requirements (eg, CDISC, CDASH, eCTD) and guidelines (eg, ICH, CHMP, FDA, GCP).Submission support with compliance experience.Understanding of the software development life cycle. WHAT YOU WILL CONTRIBUTE Provides comprehensive programming leadership and support to clinical project teams and vendors, including deployment of programming strategies, standards, specifications and programmed analysis to comply with regulatory requirements, SOPs and work practices.Develops unambiguous and robust programming specifications (e.g. WHAT WE SEEK Strong professional experience in a similar role within the pharmaceutical industry, preferably vaccines.Ability to effectively communicate and perform in a high demand and dynamic working environment.Well organized with the ability to multitask, prioritize, and manage shifting responsibilities in a dynamic, cross-functional teamwork environment.Works effectively with cross functional groups, study team, and vendors.Excellent collaboration skills with strong attention to detail and the ability to multi-task and manage complexity.Strong interpersonal and organizational skills and excellent verbal and written communication skills are required.NDA submission experience is a plus.Bachelor's degree in Statistics, Computer Science, Mathematics, or related technical discipline. Our corporate culture is dynamic, diverse, and creative.
Director, Digital & Omnichannel Marketing
Company: Corcept Therapeutics
Location: Peninsula
Posted Aug 04, 2023
Advanced degree (M.B.A., PhD.) )Experience optimizing owned properties (CortisolMatters.com, Korlym.com/hcp, Korlym.com) to enhance user experience, streamline content and capture data (i.e. )Experience creating digital infrastructure (CRM, marketing auto., data ecosystems & optimization software)Experience with personal/non-personal, branded/unbranded and digital omni-channel promotionDemonstrated ability to drive cross-functional consensus with complex concepts and initiativesDemonstrated ability to translate strategic direction into effective digital promotion tacticsExperience partnering with marketers and directing agencies of record, for digital promotion and mediaAdditional Qualifications Bachelor’s degree required. ), as relates to digital marketing effortsCollaborate with IT, Corporate Comms. is advantageous.10+ years of biopharmaceutical experience with 5-10 years in patient/provider marketing, marketing operations and/or digital/omni-channel marketing. clear calls to action)Expert digital media optimization (SEO, web, programmatic), experience designing multi-touch attribution and/or “next best action(s)” and has led digital media strategy (paid, owned & earned)Digital content creation experience (developed strong pull tactics to engage patients/providers)Has built owned, on-demand learning properties/portals for providers (or patients) that includes content from disease state education, speaker decks and virtual webinar sessionsExperience building /patient databases of qualified leads and CRM programs leveraging optimized owned properties and experience building data base of leads and CRM programs leveraging owned properties.Subject matter expert on emerging trends in digital marketing practices and emerging regulatory trendsExpert ability to create and monitor digital metrics via strategic dashboards (customer conversion rates) , tactical optimization (unique visitors, bounce rates, customer conversion rates, etc. New product launch experience is preferred.Marketing or Marketing Ops experience in a combination of small and large biopharmaceutical companiesAdvanced understanding of relevant legal, regulatory and business compliance considerations is required.Experience working in startup or emerging biopharmaceutical firms is desiredExcellent interpersonal skills with ability to lead, interact with, focus, resolve conflict and drive consensus among individuals from a variety of cultures, and disciplines. The position will be based in Menlo Park/Bay AreaThe pay range that the Company reasonably expects to pay for this position is $218,000 - $257,000; the pay ultimately offered may vary based on legitimate considerations, including job-related knowledge, skills, experience, and education. An annual cash bonus and equity grants may be provided as part of the overall compensation package, in addition to a full range of medical, financial, and/or other wellness benefits, dependent on the position offered. Applicants must be currently authorized to work in the United States on a full-time basis.If you are based in California, we encourage you to read this important information for California residents linked here.Corcept appreciates the commitment and hard work of all our team members as we strive to discover and develop novel treatments for patients with serious unmet medical needs. Please visit our website at: https://www.corcept.com/Corcept is an Equal Opportunity Employer and others to gain alignment on cross-functional initiativesDesired Experiences Established and led cross-functional forums to build digital marketing infrastructure & plans; established governance and use-case roadmaps (phased and clear near/mid/long-term plans)Broad digital channel management & integration experience (social, web, email, etc. mobile number and email, NPI)Developed content that drives to owned properties (e.g.
Senior Manager / Associate Director Biostatistics
Company: Corcept Therapeutics
Location: Peninsula
Posted Aug 03, 2023
Corcept is a successful company specializing in the development of drugs to treat severe disorders by modulating cortisol activity. They have marketed Korlym for Cushing's syndrome since 2012, generating $402 million in revenue and $101 million in net income in 2022. Their portfolio includes over 1,000 proprietary selective cortisol modulators, with lead compounds in various stages of trials for multiple disorders. They plan to initiate a Phase 2b trial for NASH by the end of the year. The Senior Manager/Associate Director Biostatistics will lead statistical components of Corcept's development programs, managing external statisticians and statistical programmers. The role involves partnering with various departments, overseeing statistical components of clinical studies, and ensuring regulatory compliance.
Product Manager, Marketing
Company: Corcept Therapeutics
Location: Peninsula
Posted Aug 04, 2023
Endocrinology and/or orphan drug experience a plusThe pay range that the Company reasonably expects to pay for this position is $165,000 - $194,000; the pay ultimately offered may vary based on legitimate considerations, including job-related knowledge, skills, experience, and education. An annual cash bonus and equity grants may be provided as part of the overall compensation package, in addition to a full range of medical, financial, and/or other wellness benefits, dependent on the position offered. Applicants must be currently authorized to work in the United States on a full-time basis.If you are based in California, we encourage you to read this important information for California residents linked here.Corcept appreciates the commitment and hard work of all our team members as we strive to discover and develop novel treatments for patients with serious unmet medical needs. Please visit our website at: https://www.corcept.com/Corcept is an Equal Opportunity Employer Veeva)Responsible for overseeing and updating the Corcept marketing material warehouseCollaborate and partner closely with key cross functional stakeholders (internal/external)Assist in the planning, development, and pull through of market research initiatives to help better inform brand strategy and directionPartner closely with PRC to ensure all marketing activities comply with medical, regulatory, and legal requirementsFoster relationships with thought leaders, key customers, and various medical associationsManage agency relationships in the development, implementation, execution, and production of HCP materials across multiple marketing channelsDemonstrate excellent project management skills and the ability to manage multiple projects running in parallelHelp manage and track the HCP Promotions marketing budget and participate in the budget planning processManage timely and effective communication channels between sales force and marketingTravel requiredPreferred Skills, Qualifications and Technical Proficiencies: Strong understanding of traditional and non-traditional marketing channels, with emphasis on print and digitalAbility to influence internal cross-functional teams, and successfully manage multiple projects and agencies simultaneouslyVendor/agency background experience a plusPreferred Education and Experience: Bachelor's degree or equivalent, master's degree preferredExperience evaluating data using Salesforce, Veeva or equivalent5+ years of pharmaceutical or biotechnology experience2-4 years’ experience in brand management. Responsibilities also include pull-through and execution of the commercial plan, overall life cycle management, and budget. Responsibilities:Manage the execution of marketing strategies that meet and align to brand objectivesDrive marketing efforts that meet/exceed brand goals and corporate objectives, while closely following internal and external processesWork with marketing team to ensure all HCP creative/content is aligned between print and digital promotional assetsManage all HCP promotional marketing materials across different marketing platforms (ex. In 2022, we generated revenue of $402 million and net income of $101 million.We have discovered a portfolio of more than 1,000 proprietary selective cortisol modulators. Our lead compounds are in Phase 2 and Phase 3 trials for the treatment of patients with Cushing’s syndrome, advanced ovarian cancer, castration-resistant prostate cancer and amyotrophic lateral sclerosis (“ALS”). We plan to initiate a Phase 2b trial in patients with non-alcoholic steatohepatitis (“NASH”) by the end of this year. Every year, we advance new molecules to the clinic.Over the next few years, we expect to submit several new drug applications.The Product Manager will contribute to the strategic and tactical marketing responsibilities centered around Korlym’s indication and disease state education. This role will report to the Associate Director, Marketing. Responsibilities include, but are not limited to, healthcare professional (HCP) strategy and content development, creation and execution of HCP tactics and initiatives including positioning, messaging, and creative development. Since 2012, we have marketed Korlym® for the treatment of patients suffering from Cushing’s syndrome, a life-threatening orphan disorder caused by excess cortisol activity. This role will partner closely with Thought Leader Programming and various commercial cross functional departments to ensure alignment between HCP educational materials and marketing content. Corcept is a commercial-stage company engaged in the discovery and development of drugs to treat severe endocrine, metabolic, oncologic and neurological disorders by modulating the effects of the hormone cortisol.
Executive Assistant, Research & Development
Company: Jnana Therapeutics
Location: Boston, MA
Posted Aug 04, 2023
This will be a highly visible and rewarding role with the potential to have a significant impact on business success and the culture we're building at Jnana.ResponsibilitiesLead Executive Assistant to the Research & Development leadership teamManage multiple calendars and execute complex schedules and travel itineraries with internal and external stakeholdersSeamlessly coordinate meetings and team events, including room bookings, venue selection, materials creation and managementManage and execute critical administrative workflows and provide organizational solutions to increase team effectivenessPartner closely with key internal stakeholders, including other administrative team members, to ensure synchronization of effortsProactively identify potential roadblocks for team and effectively troubleshoot and/or appropriately escalateServe as an ambassador of Jnana's culturePreferred Qualifications & Past ExperiencePrevious experience as an Administrative or Executive Assistant in the biotech/pharma industryExperience supporting VP, SVP and C-level executivesSkilled in complex calendar and meeting managementOutstanding communication skills, including written and verbal, with internal and external partiesHighly organized, solutions-oriented, and pro-active For more information, please visit www.jnanatx.com and follow us on Twitter and on LinkedIn.About the OpportunityJnana Therapeutics is seeking an experienced Executive Assistant to support our Research & Development team, including our CMO and Head of Research & Development. The most successful candidates will have previous biotech or pharmaceutical industry experience, strong communication skills, and demonstrated ability to partner effectively with both internal and external stakeholders. Located in Boston, Jnana brings together scientific leaders in small molecule drug discovery and development, a highly experienced management team and the backing of leading life science investors Bain Capital Life Sciences, RA Capital Management, Polaris Partners, Versant Ventures, Avalon Ventures, Pfizer Ventures and AbbVie Ventures. Ideal candidates will bring a passion for leveraging strong management and organizational skills to help leaders achieve critical goals. Jnana's wholly owned lead program is a potential first-in-class oral approach, targeting an allosteric site on the phenylalanine transporter SLC6A19, for the treatment of phenylketonuria (PKU), a rare genetic metabolic disease. This is a fantastic opportunity to join a fast-paced and dynamic team of brilliant clinical and research leaders and play an important role in our future. Jnana is focused on developing first- and best-in-class therapies to treat a wide range of diseases, including rare diseases, immune-mediated diseases and cancer. About UsJnana Therapeutics is a clinical-stage biotechnology company leveraging its next-generation chemoproteomics RAPID platform to discover medicines for highly validated, challenging-to-drug targets to treat diseases with high unmet need.
IT Network Engineer
Company: Shape Therapeutics
Location: Seattle, WA
Posted Aug 04, 2023
We welcome individuals from all backgrounds who possess experience in information systems, information technology, and engineering. What You’ll DoDesign, implement, maintain, and monitor, the corporate network and other data communication systems to ensure network connectivity throughout the organization, across multiple sites.Manage and expand network interconnections, network co-location sites and points of presence (POPs).Monitor and improve network performance and reliability based upon system performance metrics, including capacity planning, failure detection and remediation. In addition, this position will build processes and systems, identify business opportunities, collaborate with cross-functional teams, scale up IT Infrastructure, and maintain our cybersecurity posture. We are dedicated to applying generative AI to revolutionize how gene editing, delivery, expression, and manufacturing are done for gene therapy. Proactively identify and resolve issues to ensure optimal network operation and performance.Configure and install various network devices, including routers, switches, firewalls, load balancers, and wireless access points.Collaborate with internal teams to gather network requirements and design security-first, right-sized, scalable solutions that address business needs.Implement and maintain network security measures, including firewalls, intrusion detection systems, and virtual private networks (VPNs), to protect the organization's data, people, and systems.Collaborate with cloud team to manage and improve cloud (AWS) connectivity, security posture, and user management.Perform network capacity planning and recommend upgrades or enhancements to ensure availability, scalability, and performance.Troubleshoot end-to-end connectivity problems, including troubleshooting of the client and server machines when needed, to provide timely resolution of network-related incidents.Conduct regular network performance testing and analysis to identify areas for improvement and optimize network performance.Document network configurations, procedures, and troubleshooting steps to maintain an up-to-date network infrastructure knowledge base.Stay up to date with emerging technologies and industry trends in networking and make recommendations for incorporating new technologies into the organization's network infrastructure.Partner with 3rd party and IT vendors to further grow and mature IT operations.What you BringBachelor's degree (or equivalent experience) in Information Systems, Computer Science, Computer Engineering, Information Security, or similar technical or engineering experience in a relevant field or discipline.Minimum of 3+ years of professional experience with deploying enterprise network solutions, or cloud or web-scale networks.Proficiency and experience with two or more of; Palo Alto Networks firewalls (including Panorama), Cisco route/switch/wireless, Cisco Meraki switch/wireless, and Bigleaf Networks, is highly preferred.Experience configuring and operating network routing protocols including BGP and OSPF.Experience with two or more of; macOS, Windows 10/11, Windows Server, and/or Linux, is preferred.Experience navigating AWS networking preferred.Experience with AWS identity (IAM/SSO) and security services is a bonus.Demonstrated experience to meet deadlines, multi-task, and to prioritize incoming demands, based on business goals.Ability to solve complex problems and identify root causes independently.Collaborative team player with excellent organizational and interpersonal skillsAbility to take initiative and implement new processes, systems, and technology with appropriate levels of documentation.Ability to work effectively in a fast-paced and high-pressure environment.Strong attention to detail and accuracy.Takes ownership and possesses a continuous learning attitude.Excellent written and verbal communication skills.Compensation & BenefitsShapeTX offers a robust benefits package, including but not limited to: Medical, Dental and Vision coverage for employees and their eligible dependents. We are proud to offer a competitive paid parental leave benefit, an annual employee stipend for employees to use however they choose, a Flex Paid Time Off program (allowing flexible PTO for vacation, sick leave, and other purposes) and Company paid Long Term Disability. Employees are eligible to enroll in our Company’s voluntary 401k plan, voluntary Life/AD&D and Voluntary FSA’s.The salary range for this role is $96,000-$144,000. not only through our science, but also through our commitment to foster an inclusive environment that supports diverse perspectives and experiences. Additional compensation may include annual target bonus and/or sign-on bonus, equity grant and relocation bonus.We aspire to Shape Life! We believe in the power of diverse perspectives to drive innovation in gene therapy and are committed to creating an environment where integrity, patient impact, and personal growth are valued. Through diversity of thought, scientific knowledge, professional rigor and focus we are merging cutting-edge science with extensive drug development expertise to unlock cures to many debilitating diseases.Shape Therapeutics is headquartered in Seattle, Washington with a satellite site in Boston, Massachusetts. The hired applicant's placement within the range is based on qualifications and professional experience.
Scientist I/II, Neuroscience
Company: Voyager Therapeutics
Location: Cambridge
Posted Aug 02, 2023
In this position, you will independently design and execute rodent in vivo experiments to support Development Candidate nomination following the in vitro target identification. Lastly, the Scientist I/II will bring their ex vivo expertise to process the tissues from the in vivo studies, likely with assays such as ddPCR, RT-qPCR, binding assays, activity assays, and/or immunohistochemistry.Key Responsibilities:Design, execute experiments, analyze data, and write reports (both written and verbal) for AAV platform discovery research.Perform cell culture for multiple cell lines to support in vitro target engagement.Conduct analysis including various DNA, mRNA and protein assays from both tissue and cell culture.Design and execute rodent in vivo experiments.Conducts ex vivo tissue, CSF and serum analysis (ELISA, western blot, RT-qPCR, etc. Strong background in cell culture, in vivo experimental methods, and readouts.Hands-on experience with molecular and cellular techniques including ELISA, RT-qPCR, ddPCR, and biochemical assay development.Outstanding problem-solving skillsAbility to read and interpret the literature to support advancement of programs and/or platform discovery research.Ability to be highly productive in a fluid and fast-paced work environment.Good communication skills and ability to multi-task.Ability to analyze and present data independently to the research teams.Strong commitment to accountability for completion of projects in accordance with team and company plans.Excellent organizational skill and attention to detail.Ability to thrive in a team-oriented, fast-paced, and cross-disciplinary start-up biotech environment.Preferred ExperiencesStrong preference for a candidate with experience in AAV gene therapyPrior related experience, ideally with a biotechnology or other life sciences company, is preferred but not required.Prior experience in drug discovery for neurodegenerative diseases would be preferred. The individual will have the ability to work independently in the laboratory and be responsible for experimental execution of research studies supporting cutting edge therapeutic programs and platform discovery research in neurodegenerative disease areas. The ideal candidate would have the ability to independently conduct both in vitro, in vivo and ex vivo studies/analysis.The Scientist I/II will support target validation using cell culture with RT-qPCR, ddPCR, binding assays such as Octet/Biacore, activity assays, western blot and/or immunocytochemistry as readouts. )Performs data analyses independently as well as delivers effective data presentations to the research teams.Ensures maintenance of industry-quality records to provide documentation.QualificationsA PhD degree with 0-2+ years, MS with 7+ years or BS with 8+ years’ experience in the field of Neuroscience, Pharmacology or related discipline is required. Voyager’s pipeline includes preclinical programs in Parkinson’s disease, Alzheimer’s disease, and amyotrophic lateral sclerosis (ALS), each with validated targets and biomarkers to enable a path to rapid potential proof-of-biology. This is an ideal position for an individual with hands-on experience supporting programs from in vitro target validation to in vivo development candidate nomination who thrives in a team-oriented, fast-paced, and cross-disciplinary start-up biotech environment. For more information, visit www.voyagertherapeutics.comJob Summary:We are seeking a highly motivated Scientist I/II to contribute to our Neuroscience team at our facility in Cambridge, Massachusetts. This platform is fueling alliances with Pfizer Inc., Novartis and Neurocrine Biosciences as well as multiple programs in Voyager’s own pipeline. Voyager’s TRACER AAV capsid discovery platform has generated novel capsids with high target delivery and blood-brain barrier penetration at low doses, potentially addressing the narrow therapeutic window associated with conventional gene therapy delivery vectors. The potential of both disciplines has been constrained by delivery challenges; Voyager is leveraging innovative expertise in capsid discovery and deep neuropharmacology capabilities to address these constraints.
Senior UX Researcher
Company: Click Therapeutics
Location: New York City, NY
Posted Aug 04, 2023
Click Therapeutics will conduct interviews face-to-face over Zoom. Employment applicants requiring immigration sponsorship must disclose, when initial application for employment is made, whether or not they are legally authorized to work for Click Therapeutics in the U.S. and, if so, whether that authorization permits them to work in the job they seek. All job postings will be listed on the Click Therapeutics official career page. If someone contacts you about a job or position that is not listed on the official career page, please contact the Click Therapeutics recruitment team at the contact information below. If you have any questions regarding the validity of a recruitment inquiry or an interview, please contact the Click's recruitment team at [email protected] to confirm before proceeding. Competitive Salary with Annual Review | Annual Performance-Based Cash Bonus | Stock options | 5% 401(k) matching | Comprehensive Medical Benefits | Dental | Vision | Voluntary Benefits | Unlimited PTO | Uber One | Nectar Rewards | One Medical | Fertility Support | Gym Pass | Citi Bike | Professional Development Stipend | Weekly Grubhub Lunches | Generous Paid Parental Leave | Industrious Workspaces | Commuter Subsidies | Choice of Mac or Windows | Sponsored Company Events | Office Snacks and Beverages | Much More...Equal Employment Opportunity:Click Therapeutics is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Proficiency in research tools such as Dscout, Dovetail and UserTesting.com Bachelor's or Master's degree in Human Computer Interaction, Cognitive Psychology, Information Science, Anthropology, Sociology, or related technical field Compensation: The base salary range for this position is between: $137,000 - $190,000. The final base salary will be dependent upon skills, experience and location. Click Therapeutics may at its business discretion decide to or refrain from obtaining, maintaining and/or extending the temporary visa status and/or sponsoring a colleague for permanent residency and /or employment eligibility, considering factors such as availability of qualified U.S. workers and the colleague's long-term prospects for securing lawful permanent residence, among other reasons. Other than your email address or telephone number, which you may provide via a job application portal, Click Therapeutics will never ask you to provide personally identifiable information about yourself (such as a Social Security Number or Driver's License Number) via a messaging application (like that used on the LinkedIn platform or Microsoft Teams).
Scientist I/II, Neuroscience
Company: Voyager Therapeutics
Location: Cambridge
Posted Aug 02, 2023
In this position, you will independently design and execute rodent in vivo experiments to support Development Candidate nomination following the in vitro target identification. Lastly, the Scientist I/II will bring their ex vivo expertise to process the tissues from the in vivo studies, likely with assays such as ddPCR, RT-qPCR, binding assays, activity assays, and/or immunohistochemistry.Key Responsibilities:Design, execute experiments, analyze data, and write reports (both written and verbal) for AAV platform discovery research.Perform cell culture for multiple cell lines to support in vitro target engagement.Conduct analysis including various DNA, mRNA and protein assays from both tissue and cell culture.Design and execute rodent in vivo experiments.Conducts ex vivo tissue, CSF and serum analysis (ELISA, western blot, RT-qPCR, etc. For more information, visit www.voyagertherapeutics.com.Voyager Therapeutics® is a registered trademark, and TRACER™ is a trademark, of Voyager Therapeutics, Inc.Job Summary:We are seeking a highly motivated Scientist I/II to contribute to our Neuroscience team at our facility in Cambridge, Massachusetts. Strong background in cell culture, in vivo experimental methods, and readouts.Hands-on experience with molecular and cellular techniques including ELISA, RT-qPCR, ddPCR, and biochemical assay development.Outstanding problem-solving skillsAbility to read and interpret the literature to support advancement of programs and/or platform discovery research.Ability to be highly productive in a fluid and fast-paced work environment.Good communication skills and ability to multi-task.Ability to analyze and present data independently to the research teams.Strong commitment to accountability for completion of projects in accordance with team and company plans.Excellent organizational skill and attention to detail.Ability to thrive in a team-oriented, fast-paced, and cross-disciplinary start-up biotech environment.Preferred ExperiencesStrong preference for a candidate with experience in AAV gene therapyPrior related experience, ideally with a biotechnology or other life sciences company, is preferred but not required.Prior experience in drug discovery for neurodegenerative diseases would be preferred. The individual will have the ability to work independently in the laboratory and be responsible for experimental execution of research studies supporting cutting edge therapeutic programs and platform discovery research in neurodegenerative disease areas. The ideal candidate would have the ability to independently conduct both in vitro, in vivo and ex vivo studies/analysis.The Scientist I/II will support target validation using cell culture with RT-qPCR, ddPCR, binding assays such as Octet/Biacore, activity assays, western blot and/or immunocytochemistry as readouts. This platform is fueling alliances with Pfizer Inc., Novartis Pharma AG, Neurocrine Biosciences, Inc., and Sangamo Therapeutics, Inc., as well as multiple programs in Voyager’s own pipeline. )Performs data analyses independently as well as delivers effective data presentations to the research teams.Ensures maintenance of industry-quality records to provide documentation.QualificationsA PhD degree with 0-2+ years, MS with 7+ years or BS with 8+ years’ experience in the field of Neuroscience, Pharmacology or related discipline is required. Voyager’s pipeline includes wholly owned and collaborative preclinical programs in Alzheimer’s disease, amyotrophic lateral sclerosis (ALS), Parkinson’s disease, and other diseases of the central nervous system, with a focus on validated targets and biomarkers to enable a path to rapid potential proof-of-biology. This is an ideal position for an individual with hands-on experience supporting programs from in vitro target validation to in vivo development candidate nomination who thrives in a team-oriented, fast-paced, and cross-disciplinary start-up biotech environment. Voyager’s TRACER™ AAV capsid discovery platform has generated novel capsids with high target delivery and blood-brain barrier penetration at low doses, potentially addressing the narrow therapeutic window associated with conventional gene therapy delivery vectors. About&8239;Voyager Therapeutics Voyager Therapeutics (Nasdaq: VYGR) is a biotechnology company dedicated to breaking through barriers in gene therapy and neurology.