Mathematical Analyst

Summary Join NIST as a Mathematical Analyst performing research in Topological Data Analysis (TDA) applied to biological and chemical data. You will analyze molecular dynamics and Markov Chain Monte Carlo (MCMC) simulations, collaborate across scientific disciplines on mission-critical projects, and disseminate findings through published manuscripts and technical presentations. Learn more about this agency Duties As a Mathematical Analyst, you will conduct cutting-edge research in mathematical modeling and Topological Data Analysis (TDA), focusing on high-dimensional biological and chemical datasets. You will apply topological frameworks to both experimental measurements and computational simulations to solve complex measurement science challenges. Major duties are: Conduct Advanced TDA Research: Perform mathematical modeling and research applying Topological Data Analysis (TDA) to interpret complex, high-dimensional biological and chemical datasets. Analyze Simulation and Measurement Data: Model and process diverse data types, including empirical measurements, molecular dynamics trajectories, and Markov Chain Monte Carlo (MCMC) simulations. Resolve Chemometric and Biosensor Challenges: Apply TDA techniques to diverse modalities, including BioFET time-series instrument outputs, chemical forensics via mass spectrometry, and PFAS/monoclonal antibody classifications. Collaborate on Cross-Disciplinary Projects: Engage with multidisciplinary NIST scientists to contribute mathematical expertise to mission-critical, agency-wide research initiatives. Disseminate Scientific Findings: Author and publish research results in peer-reviewed manuscripts, and deliver technical talks and presentations at scientific conferences. Requirements Conditions of employment U.S. citizenship Males born after 12-31-59 must be registered for Selective Service Suitable for Federal employment Bargaining Unit Position: No Qualifications Basic Requirements: A. Degree: mathematics, or the equivalent of a major that included at least 24 semester hours in mathematics. OR B. Combination of education and experience -- courses equivalent to a major in mathematics (including at least 24 semester hours in mathematics), as shown in A above, plus appropriate experience or additional education. The total coursework in either A or B above must have included differential and integral calculus and, in addition, four advanced mathematics courses requiring calculus or equivalent mathematics courses as a prerequisite. In addition to the above basic requirements, all applicants must have one year (52 weeks) of specialized experience equivalent to at least the GS-9 level (ZP-II at NIST). The specialized experience is defined as: Experience applying Topological Data Analysis (TDA) Experience utilizing computational methods and workflows to process, analyze, and interpret biophysical, biological, or chemical data generated from molecular dynamics trajectories or Markov Chain Monte Carlo (MCMC) simulations. Experience with contributing to complex scientific research projects by collaborating across technical disciplines (e.g., mathematics, biology, chemistry). OR Master's or equivalent degree OR A combination of education and experience Experience refers to paid and unpaid experience, including volunteer work done through National Service programs (e.g., Peace Corps, AmeriCorps) and other organizations (e.g., professional, philanthropic, religious, spiritual, community, student, social). Volunteer work helps build critical competencies, knowledge, and skills, and can provide valuable training and experience that translates directly to paid employment. You will receive credit for all qualifying experience, including volunteer experience. The qualification requirements in this vacancy announcement are based on the U.S. Office of Personnel Management (OPM) Qualification Standards Handbook. If requesting reconsideration of your qualification determination, please refer to the following site: Applicant Reconsideration Education This position has an education requirement. Transcripts must be submitted to validate that the education requirement has been met. Unofficial transcripts will be accepted in the application package. However, an official copy will be required before a final offer of employment. Use of foreign education for qualifications. An accredited organization must evaluate education completed outside of the U.S. to ensure that it is comparable to education received in accredited institutions in the U.S. Click here to view a listing of accredited organizations from the Department of Education's website. A copy of the foreign education evaluation (containing the results with a course-by-course listing) is required with your application. Additional information This notice is issued under direct-hire authority to recruit new talent to occupations for which NIST has a severe shortage of candidates. This position is covered under NIST's Alternative Personnel Management System (APMS), a pay-for-performance system with excellent HR flexibilities to help NIST recruit and retain top talent. Learn more about the APMS here! We may share your application package with other selecting officials. Additional selections may be made through this vacancy. Click all links in this vacancy announcement to view additional information or instructions. You MUST select at least ONE ELIGIBILITY to be considered for this position. All documents submitted for this announcement must be legible to make qualification or eligibility determinations. A probationary period may be required. NIST strives to build a flexible and encouraging work environment to bring out the best in our employees. To help our employees balance responsibilities at home and at work, NIST offers a variety of work-life flexibilities. For more information, please visit our Careers website. Expand Hide  additional information Candidates should be committed to improving the efficiency of the Federal government, passionate about the ideals of our American republic, and committed to upholding the rule of law and the United States Constitution. Benefits A career with the U.S. government provides employees with a comprehensive benefits package. As a federal employee, you and your family will have access to a range of benefits that are designed to make your federal career very rewarding. Opens in a new windowLearn more about federal benefits. Review our benefits Eligibility for benefits depends on the type of position you hold and whether your position is full-time, part-time or intermittent. Contact the hiring agency for more information on the specific benefits offered.