Job Description
We're looking for a Senior Research Scientist on our Statistical Programming team who is well-versed in R and real-world evidence to help us accomplish our mission to improve and extend lives by learning from the experience of every person with cancer. Are you ready to be the next changemaker in cancer care?
What You'll Do
In this role you will work as a member of the Statistical Programming team within the Research Sciences (RS) department primarily supporting the Custom Solutions and Services (CSS) team. This team provides customized real-world data and real-world evidence solutions to address the most important research questions across clinical development market access and commercial use cases for our life sciences partners. As part of CSS you will:
- Provide scientific oversight for the programming of statistical analyses on multiple simultaneous research projects
- Provide consultation on complex epidemiologic/statistical methods study design data limitations and data models to other statistical programming staff
- Independently translate analytic specifications from a statistical analysis plan into R code to create analytic datasets generating descriptive and inferential statistics data visualizations often involving novel variables or complex statistical methods in consultation with the study principal investigator
- Serve as subject matter expert on appropriate use cases for and nuances of the variety of different Flatiron data modalities including EHR-derived real-world data clinico-genomics data ML-extracted data and claims data
- Apply expertise in cancer biology therapy and/or epidemiology across multiple major tumor types to analytic code and scientific oversight
- Provide mentorship and support to other statistical programming staff
- Collaborate with cross-functional stakeholders across our medical and scientific organization to execute and deliver on client-sponsored research studies in an accurate effective and timely manner
- Lead initiatives for the continuous improvement of Flatiron's proprietary analytical tooling
Who You Are
You're a kind passionate and collaborative problem-solver. In addition you're an analytical thinker and excellent communicator with experience analyzing real-world data (e.g. healthcare claims or electronic health records). You're excited by the prospect of rolling up your sleeves to tackle meaningful problems each and every day.
- You hold a Doctorate degree (e.g. PhD ScD DrPH) in Biostatistics/Statistics Data Science Bioinformatics Biological Sciences Public Health Math or a closely related field with 4-5+ years of relevant experience or a Master's degree with 7-8+ years of relevant experience
- You have a deep understanding of real-world data and related epidemiology and biostatistics methodologies used to generate real-world evidence
- You are an excellent programmer in R (including tidyverse) and are proficient working in Git-based environments (e.g. Github Gitlab)
- You have extensive experience conducting analyses with large healthcare-related datasets (e.g. administrative claims electronic medical records genomics)
- You possess the data curiosity to proactively identify and solve for unexpected patterns
- You have strong leadership communication prioritization and decision-making skills necessary to oversee evaluate plan and implement multiple high-visibility projects in a timely fashion
- You have the ability to lead projects and people effectively in a constantly changing diverse and matrix environment
- You have a growth mindset are willing to learn from others and are dedicated to promoting a psychologically safe environment
- You are passionate about our mission to improve healthcare through technology
Extra credit
- You have experience working with oncology datasets
- You can write SQL queries
- You have experience in predictive modeling
- You have experience leading teams either as a manager or project/team lead
Where you'll work
In this hybrid role you'll have a defined work location that includes work from home and 3 office days set by you and your team. For more information on our approach to hybrid work please visit the how we work website.
Preferred Primary Location: Durham office
The annual pay range reflected above for this position is based on the preferred primary location of the role which is listed in the job description. Salary ranges for other locations vary from the range reflected above. Base pay offered may vary depending on job-related knowledge skills and experience. An annual bonus and equity may be provided as part of the compensation package in addition to a full range of medical financial and/or other benefits dependent on the position offered.
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What the Team is Saying



What We Do
Flatiron Health is a healthtech company dedicated to helping cancer centers thrive and deliver better care for patients today and tomorrow. Through clinical and data science we translate patient experiences into real-world evidence to improve treatment inform policy and advance research. Cancer is smart. Together we can be smarter. Flatiron Health is an independent affiliate of the Roche Group.
Why Work With Us
Reimagine the infrastructure of cancer care within a technology and science community that values integrity inspires growth and is uniquely positioned to create a more modern connected oncology ecosystem.
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Hybrid Workspace
Employees engage in a combination of remote and on-site work.
At Flatiron attracting and inspiring a diverse team is essential to our success. Our hybrid work approach built on flexibility and clarity allows you to choose your office days while optimizing productivity and well-being.
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Date Posted
04/13/2026
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