Staff Site Reliability Engineer (SRE) | Dev Ops Engineer

Reponsibilities

• Design build and operate highly available fault-tolerant cloud infrastructure across AWS GCP and/or Azure
• Architect and maintain scalable CI/CD pipelines and deployment frameworks for enterprise-grade software delivery
• Lead infrastructure-as-code adoption and maturity using tools such as Terraform CloudFormation and Ansible
• Own Kubernetes reliability across multi-cluster environments including upgrades scaling and workload lifecycle management
• Establish and evolve observability platforms (metrics logs traces) and define SLO/SLI frameworks across teams
• Lead incident response for critical outages drive root cause analysis and implement preventative improvements
• Optimize infrastructure for cost performance and scalability partnering closely with engineering and finance stakeholders
• Define and enforce DevOps reliability and security best practices across the organization
• Partner cross-functionally with engineering data QA security and IT teams to design resilient systems
• Mentor engineers and contribute to technical leadership through design reviews standards and knowledge sharing

These responsibilities summarize the role’s primary responsibilities and are not an exhaustive list. They may change at the company’s discretion.

What Success Looks Like in Your First Year
• Conduct a comprehensive assessment of the current infrastructure drive infrastructure-as-code adoption to 95%+ across critical systems and establish clear health and reliability baselines for the Kubernetes platform
• Standardize observability using modern tooling and implement an SLO/SLI framework adopted across multiple product teams including defined SLAs for critical data systems
• Strengthen security and compliance posture across cloud environments by implementing consistent baselines launching a compliance-as-code framework and reducing mean time to resolution (MTTR) for production incidents
• Define document and drive adoption of engineering standards best practices and operational guidelines across platform and product teams
• Develop and align stakeholders on a forward-looking platform reliability and infrastructure roadmap
• Demonstrate measurable mentorship and technical leadership impact across the engineering organization
• Evaluate and provide recommendations on emerging infrastructure needs including support for AI/ML and advanced data workloads

Required Qualifications

• BS in Computer Science Engineering or related field or equivalent experience
• 8+ years of experience in Site Reliability Engineering DevOps or platform engineering
• Strong hands-on experience with at least one major cloud platform (AWS GCP or Azure)
• Experience implementing infrastructure-as-code solutions (Terraform CloudFormation or similar)
• Experience designing and operating CI/CD pipelines (e.g. GitLab CI GitHub Actions Jenkins)
• Hands-on experience with Kubernetes and containerized systems in production environments
• Proficiency in scripting or programming for automation (e.g. Python Go Bash or PowerShell)
• Experience with observability and monitoring tools (e.g. Prometheus Grafana OpenTelemetry Datadog)
• Strong understanding of networking security and distributed systems fundamentals
• Experience working in regulated environments and familiarity with frameworks such as ISO 27001 NIST SOC 2 or HIPAA

Preferred Qualifications

• 10+ years of experience in SRE DevOps or infrastructure engineering
• Experience operating multi-cluster Kubernetes environments (e.g. EKS GKE) at scale
• Familiarity with GitOps practices (e.g. ArgoCD Flux)
• Experience with data platforms and pipelines (e.g. Kafka Airflow Spark Snowflake BigQuery)
• Experience implementing SLO/SLI frameworks and reliability practices across multiple teams
• Strong background in cloud security including IAM zero-trust architecture and secrets management
• Experience with compliance-as-code and security tooling (e.g. OPA Snyk Checkov)
• Exposure to AI/ML or large-scale data infrastructure workloads
• Experience in healthcare biotech or other regulated industries
• Relevant cloud or Kubernetes certifications (e.g. AWS DevOps CKA/CKS GCP DevOps)

Physical Demands and Working Environment

Standard office environment with hybrid flexibility
Participation in on-call rotation and after-hours support for critical systems may be required
Frequent collaboration with cross-functional and senior stakeholders
Fast-paced dynamic environment with emphasis on reliability scalability and innovation

Adaptability and Growth Expectation

As the organization evolves responsibilities may expand or shift to meet business needs. This may include:
• Taking on additional technical or leadership responsibilities
• Participating in cross-functional initiatives and strategic projects
• Adapting to new technologies tools and methodologies
• Supporting other teams during periods of high demand

What We Do

GRAIL is a healthcare company whose mission is to detect cancer early when it can be cured. GRAIL is using the power of high-intensity sequencing population-scale clinical studies and state-of-the-art computer science and data science to enhance the scientific understanding of cancer biology and to develop and commercialize pioneering products.

Why Work With Us

Everything we do is guided by our mission to detect cancer early when it can be cured. It’s the reason we’re here and it’s no small task. The right people make all the difference. That’s why we’re looking for those who strive to share their knowledge contribute their skills inspire each other and commit to something bigger than themselves.

Gallery