Full Time Jobs in Cambridge
4,131 open positions · Updated daily
Looking for Full Time jobs in Cambridge? Browse our curated listings with transparent salary information to find the perfect Full Time position in the Cambridge area.
Principal Research Associate/Scientist, Analytical Development
Company: eGenesis
Location: Cambridge
Posted Feb 23, 2024
PRIMARY RESPONSIBILITIES Develop, optimize, and execute robust and reproducible assays Utilize various techniques to characterize the primary cells and/or factors they produce, including flow cytometry, ELISA, conventional and real-time PCR, etc. This role is a full-time lab-based position in which being proactive, determined, responsible, coachable, and collaborative will help you thrive. Isolate, culture, and assess the function of porcine cells Communicate and present scientific findings at group and company meetings Implement superb documentation of procedures and experiments to support tech transfer Contribute to multiple research projects as they arise in our fast-paced, start-up environment Troubleshoot and optimize assays and maintain careful records Build our laboratory efforts by maintaining and creating a productive and fun environment BASIC QUALIFICATIONS Ph.D. with 2 years of industry experience, or MS degree with 4+ years of industry experience in cell biology, immunology, biochemistry or related discipline Prior experience in development and execution of assays to characterize and measure proteins and DNA using a variety of methodologies, particularly flow cytometry Proficiency in growing and maintaining mammalian cells in culture and aseptic cell culture techniques Expertise in general cellular and molecular biology techniques, including ELISA, FACS, flow cytometry, RNA/DNA isolation etc. Demonstrated experience leading a team and developing talent Strong communication and organizational skills, and ability to prioritize and multitask efficiently in a results-oriented, dynamic environment Strong interpersonal skills and ability to work in teams This role will involve significant cell culture work, including the isolation, growth and maintenance of primary cells, such as endothelial cells from various organs, and characterizing these cells using techniques such as flow cytometry and ELISA. To be successful in this role, you will leverage previous experience with immunological and genomic assays. In this role, you will lead a small team responsible for developing and qualifying methods to assess transgene expression and function in genetically modified porcine cells. This position is an excellent opportunity to help develop new gene editing and xenotransplantation products in an exciting and dynamic environment focused on cutting-edge molecular and cellular engineering technology. COMPANY MISSION At eGenesis, we aspire to deliver safe and effective human transplantable cells, tissue and organs utilizing the latest advancements in genome editing. POSITION SUMMARY We are seeking a highly motivated individual to join the Analytical Development team as a Principal Research Associate/Scientist.
Scientist, Amplicon-seq Lead
Company: Intellia Therapeutics
Location: Cambridge
Posted Feb 26, 2024
We do not discriminate in recruitment, hiring, training, promotion or any other employment practices for reasons of race, color, religion, gender, national origin, age, sexual orientation, marital or veteran status, disability, or any other legally protected status. Intellia will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law. CRISPR) is preferred Experience in managing junior scientists is preferred Strong communications and documentation skills coupled with exceptional time management skills and attention to detail LI-KO2 Covid-19 Vaccination Policy: All Intellia employees, regardless of work location, are expected to follow all applicable federal, state, and local public health regulations and guidelines, and are strongly encouraged to follow all public health recommendations, including being vaccinated for COVID-19. In this role, you will: Lead a team of junior scientists responsible for running a high throughput Illumina amplicon sequencing workflow, as well as smaller scale Pacbio amplicon sequencing workflow Ensure timely data delivery from amplicon sequencing workflow and work with the NGS team and automation team to promptly address run failures Independently and in collaboration with colleagues, apply expertise to troubleshoot and support new project needs Partner with the NGS assay team lead, automation, software engineering, and computational sciences teams, to optimize existing and develop new NGS workflows Communicate amplicon-seq process and schedule updates with submitters from diverse groups across the company Respond to submitter questions about sample submissions, run failures, and data quality Monitor, QC, and analyze data metrics, ensuring the consistent generation of high-data quality Serve as the NGS production assay process subject matter expert Work with program and platform partners to manage project queue ensuring timelines are met Manage and mentor junior-level scientists Present your or the team's work at project and larger team meetings About You: The successful candidate will have demonstrated expertise in Illumina NGS technology, molecular biology, and liquid handling automation PhD in Genomics with 0-3 years with directly relevant experience or MS with 6-9 years equivalent experience (industry experience preferred) Solid hands-on experience with Illumina library construction, quantification, sequencing, and data analysis. EEOC Statement: Intellia believes in a diverse environment, and is committed to equal employment opportunity for all its employees and qualified applicants. Experience with long read PacBio sequencing would be a bonus. The Amp-seq team is central to all research activities, and thereby critical to the development of genome editing programs and platforms. Experience with running and optimizing liquid handling automation (preferably Hamilton) Experience with high throughput workflows and LIMS systems is preferred Experience with genome editing technologies (e.g. Genomics Innovation provides state-of-the-art genomics solutions, ranging from screening different editing modalities to developing and implementing a diverse toolbox of assays to characterize the impact of genome editing. We aren't constrained by typical end rails, and we aren't out to just "treat" people.
Owner's Project Manager
Company: SMMA
Location: Cambridge
Posted Feb 17, 2024
SMMA is seeking an experienced Owner's Project Manager for K-12 school projects. The ideal candidate should have a solid understanding of the management tasks and responsibilities of an Owner's Project Manager during the study, design, and construction phases. The role involves managing project teams, evaluating and reporting on scope, schedule, and budget status, and participating in business development opportunities. SMMA is a Cambridge-based firm founded by MIT and Rensselaer alumni, known for its integrated approach to architecture, engineering, interiors, and site design. The firm offers a hybrid work-from-home policy, competitive benefits, and a mentor/protégé program.
Data Scientist, Translational Data Science (Principal Scientist)
Company: HiFiBio Therapeutics
Location: Cambridge
Posted Feb 25, 2024
Examples include: Best practices for single cell methods including data imputation and normalization, bulk deconvolution, cell type/state analysis, cell-cell interaction/trajectory inference, reconstruction of cell type specific interactomes – cellphoneDB and spatial transcriptomic analysis and visualization Pipelines for data processing and QC including visualization and integrative analysis (e.g., Nextflow, Python, shell scripts) including but not limited to quality control, alignment, variant calling, annotation, deconvolution, etc. All full-time employees are eligible for our comprehensive benefits package: Medical, Dental, and Vision insurance (Company covers 80% of the premium cost) Life, AD&D, Short-term, and Long-term Disability Insurance (100% company covers) Health Savings Account & Flexible Spending Account Telehealth Service (100% company covers) Dependent Care Pre-tax Account Parking and Commuter Pre-tax Account Unlimited PTO (Paid Time Off) 10 Paid Holidays and Sick Time (40 hours per year) 401(K) Plan Demonstrated ability to lead projects of moderate scope, mapping-out critical path, milestones and timelines, as well as manage expectations with minimal supervision. Identification and qualification of biomarkers (e.g., selection, PD, efficacy biomarkers) and analysis of data from both our clinical and research effects Assessment of treatment effects from both RNA (e.g., bulk, single cell, TCR/BCR, and spatial) and protein modalities (e.g., CITE/REAP-Seq, mIF, and high dimensional flow cytometry Develop and apply computational, AI/ML methods to analyze our multi-modal data. For example, multivariate analysis; dimensionality reduction methods; parametric and non-parametric statistical methods; Bayesian statistics; pattern recognition or classification methods Expert level fluency in statistical programming using Python, R/bioconductor or equivalents. Generative AI models to integrate and to analyze multi-modal molecular as well as patient clinical data Interactive dashboards for data visualization and interpretation What you will bring: Ph.D. in a computational, statistical, biophysics, or bioinformatics related fields A minimum of 5-years research (academia or industry) experience First-hand experience in single cell sequencing analysis and data generation methods as well as the computing infrastructure and data management methods First-hand multi-parametric data mining experience for disease endotyping, target identification and biomarker analysis. This is an on-site position in Cambridge, MA. Demonstrated experience in deep learning and generative AI model assessment is a differentiator. What you will do: Synthesize our data into actionable insights by supplying to the Translational teams any needed computational, statistical, machine learning or modeling capabilities needed to advance our clinical programs. Curiosity to dive below the surface and proactively identify critical issues including their tactical and strategic resolutions.
Senior Analyst, Quality Control
Company: Vor Bio
Location: Cambridge
Posted Feb 24, 2024
<div> <p><strong>We engineer stem cell transplants that shield healthy cells from targeted therapies<strong><p> <p>Targeted therapies work by attacking cells that express particular proteins on their surface Unfortunately both diseased and healthy cells often express the same proteins resulting in collateral damage to healthy cells<p> <p>At Vor Bio we engineer hematopoietic stem cells HSCs to lack a biologically redundant target protein then transplant these cells into the patient<p> <p>These eHSCs give rise to generations of new healthy blood cells that are effectively shielded from targeted therapies so that only the remaining cancer cells are killed We are also developing our own CART cell therapy using T cells from the same healthy donor who could potentially provide HSCs for our shielded stem cell transplant and thereby avoid issues of donormismatch We believe our CART cell therapy may enable more potent and durable responses posttransplant<p> <p>Vor Bio is aiming to cure blood cancers through our novel platform combining HSC biology genome engineering and targeted therapies to unlock treatment options previously unavailable to patients Come be a part of a passionate team striving to collaboratively develop a groundbreaking approach to cancer treatment one of medicines greatest challenges<p> <p><strong>What we value in our fellow Voracians<strong><p> <p><strong>Passion<strong> Enthusiastically driving our science toward innovative medicines<p> <p><strong>Fellowship<strong> Fostering genuine bonds of collaboration and mentorship<p> <p><strong>Humility<strong> Acting selflessly by putting the collective mission first<p> <div> <p><strong>Who we are looking for <strong><p> <p>Vor Bio is seeking an experienced Quality Control Senior Analyst who will be responsible for executing activities related to establishment release testing of raw materials to support GMP manufacturing activities as well as maintaining critical laboratory materials The individual will also support the stability program for Vor QC by maintaining schedule pull dates inventory and reporting The individual will support environmental monitoring sample collection and testing and be able to assist with EM data review and data trending This role will report directly to the Associate Director of Quality Control Critical Materials The position is onsite based in Cambridge<p> <p><strong>Key areas of responsibility<strong><p> <ul><li>Environmental Monitoring sampling testing data review and data trending<li> <li>Ensuring stability program is current and aligned with industry requirements and internal SOPs<li> <li>Raw Material program support through interface with external partners and internal cross functional partners<li> <li>Work with SMEs to prepare stability reports and laboratory management to schedule internal and external testing as appropriate<li> <li>Continuous improvement of processes that are within area of knowledge responsibility<li> <li>Work closely with Process team and receiving site QC to make sure that the analytical method transfer timeline align with process transfer timeline<li> <ul><p><strong>Qualifications<strong><p> <ul><li>Bachelors or masters degree in analytical sciences or related fields with minimum 5 years of experience in the development and approval of cell amp gene therapy products or biologics or other relevant fields<li> <li>Required experience working inwith clean rooms and proficiency in utilizing aseptic techniques in accordance with industrycompendial standards<li> <li>Good communication skills and be able to work crossfunctionally with QC QA analytical development and CTLs<li> <li>Demonstrated ability to extract scientific details and to multitask in a high paced environment<li> <li>Experience and knowledge with engineered HSCs and gene editing technologies are preferred<li> <li>Demonstrated collaboration skills working cross functionally maintain strong stakeholder relationships and influencing scientific rigor<li> <li>Demonstrated ability to draw insights from large data perform analysis and present scientific rationale<li> <ul><div> <p>By becoming a team member here at Vor youll have access to competitive health dental and vision coverage as well as life insurance and short term and longterm disability insurance We value work life balance youll benefit from discretionary time off parental leave and an excellent 401k package We also offer a generous transportation stipend to commute as you wish We are conveniently located in Cambridge with easy access to public transportation and ample parking<p> <p>As an equal opportunity employer we at Vor Bio know that diversity inspires innovation inclusiveness and creativity We invite you to come as you are All applicants will be considered for employment agnostic to race age color religion sex sexual orientation gender identity national origin veteran or disability status<p> <p>Please visit our website at httpswwwvorbiocom for more information<p> <div>
Scientist/Sr. Scientist, Genome Editing
Company: Inari
Location: Cambridge
Posted Feb 24, 2024
Inari is a SEEDesign™ company that embraces nature's diversity and complexity to drive innovation in the food system. They use predictive design and advanced multiplex gene editing to develop transformative products. Inari values a diverse team with expertise from various fields, including agriculture, human therapeutics, software, and consulting. They are seeking a Scientist/Sr. Scientist, Genome Editing to lead projects, develop gene editing tools, and contribute to their innovative culture.
Scientist/Senior Scientist, LNP Discovery
Company: Prime Medicine
Location: Cambridge
Posted Feb 19, 2024
Prime Medicine, a leading biotechnology company, is seeking a Scientist/Senior Scientist with LNP formulation experience. The candidate will design, formulate, and analyze LNPs for prime editor delivery, using microfluidics, DLS, Ribogreen, NGS, and flow cytometry. The role involves working on fast-paced projects, troubleshooting, and presenting results. Prime Medicine is an equal opportunity employer.
Research Scientist - NLP
Company: Kensho Technologies
Location: Cambridge
Posted Feb 24, 2024
<p>Kensho is a Machine Learning ML and Natural Language Processing NLP company centered around providing cuttingedge solutions to meet the challenges of some of the largest and most successful businesses and institutions We are owned by SampP Global and operate independently Our toolkit illuminates insights by helping the world better understand process and leverage messy data Specifically Kenshos solutions largely involve speech recognition ASR entity linking NED structured document extraction automated database linking text classification and more We are continuously expanding our portfolio and are looking for passionate researchers to help us create stateoftheart models across a variety of domains<p> <p><br ><p> <p>Are you looking to solve hard problems and enjoy working with teammates with diverse perspectives If so we would love to help you excel here at Kensho We are a collaborative group of experienced Research Scientists and Machine Learning Engineers whose academic backgrounds include doctorate degrees in NLP theoretical physics statistics etc We take pride in our teambased tightlyknit startuplike Kenshin community which fosters continuous learning and a communicative environment<p> <p><br ><p> <p>Since early2022 we have been building a worldclass RampD lab comprised of MLNLP Research Scientists Our small team has demonstrated compelling results and is fueling innovation throughout Kensho and SampP Global at large Specifically we are continuously building a domainspecific Large Language Model LLM and are actively working on <b>questionanswering QA summarization and document layout analysis<b><p> <p><br ><p> <p>We are looking to hire NLP Research Scientists with expertise in any of the following questionanswering summarization dialog system reinforcement learning and distributed systems In particular we are currently prioritizing <b>questionanswering<b> and are addressing<p> <p><br ><p> <p>Dialogbased QA that leverages APIs program synthesis and large knowledgegraphsdatabases to help ensure accurate answers<p> <p>Longform document QA where the answer is expected to be contained within a userspecified collection of documents<p> <p>Mathbased QA where the answer requires automatically parsing tables for relevant information and then performing basic mathematical operations to yield the correct answer eg FinQA TATQA ConvFinQA<p> <p><br ><p> <p>You will collaborate with our RampD team in conducting and publishing research in the top conferences<p> <p><br ><p> <p>At Kensho we hire talented people and give them the freedom support and resources needed to accomplish our shared goals We believe in flexibilityfirst and give our employees the opportunity to work from where they feel most productive and engaged must be in the United States We also value inperson collaboration so there may be times when travel to one of our Kensho hubs eg Cambridge MA or NYC will be required for team meetings or company events<p> <p><br ><p> <p>Kensho states that the anticipated base salary range for the position is 150k225k In addition this role is eligible for an annual incentive bonus and equity plans At Kensho it is not typical for an individual to be hired at or near the top of the range for their role and compensation decisions are dependent on the facts and circumstances of each case<p> <p><b>Technologies amp Tools We Use<b> <p><ul><li>ML PyTorch Weights amp Biases NetworkX<li> <li>Deployment Airflow Docker EC2 Kubernetes AWS<li> <li>Datastores Postgres Elasticsearch S3<li> <ul><p><b>What Youll Do<b> <p><ul><li>Regularly reading latebreaking research papers and helping to identify pertinent directions of work<li> <li>Developing novel stateoftheart NLP models that can scale to millions of documents<li> <li>Working closely with other Research Scientists and ML Engineers<li> <li>Writing clean readable research code in PyTorch not expected to write productionlevel code<li> <li>Contribute to a stellar engineering culture that values excellent design documentation testing and code<li> <li>Share your research results with your colleagues presentations and the world published papers patents and blog posts<li> <ul><p><b>What We Look For<b> <p><ul><li>Outstanding people come from all different backgrounds and were always interested in meeting talented people Therefore we do not require any particular credential or experience If our work seems exciting to you and you feel that you could excel in this position wed love to hear from you That said most of our successful candidates possess the following which reflects both our technical needs and team culture<li> <li>Hold a PhD in Computer Science or related field or a Masters with significant research experience<li> <li>Have published in a toptier MLNLP conference eg ACL NAACL EMNLP NeurIPS ICML<li> <li>Are proficient in writing code in PyTorch Tensorflow or JAX<li> <li>Have experience with the techniques required to work effectively with large messy realworld data<li> <li>Prefer to collaborate iteratively on hard problems with your teammates rather than spending stretches of time working alone and presenting your results intermittently<li> <li>Have a love for learning new skills and domains<li> <li>Are excited to share knowledge freely proactively and effectively with others who are interested<li> <li>Are a generous teammate who takes work seriously without taking yourself too seriously<li> <ul><p> <p><p><br ><p> <p><br ><p> <p>At Kensho we pride ourselves on providing topofmarket benefits including<p> <p> <p> <p> Medical Dental and Vision insurance <p> <p> 100 company paid premiums<p> <p> Unlimited Paid Time Off<p> <p> 26 weeks of 100 paid Parental Leave paternity and maternity<p> <p> 401k plan with 6 employer matching<p> <p> Generous company matching on donations to nonprofit charities<p> <p> Up to $20000 tuition assistance toward degree programs plus up to $4000year for ongoing professional education such as industry conferences<p> <p> Plentiful snacks drinks and regularly catered lunches<p> <p> Dogfriendly office CAM office<p> <p> Bike sharing program memberships<p> <p> Compassion leave and elder care leave<p> <p> Mentoring and additional learning opportunities<p> <p> Opportunity to expand professional network and participate in conferences and events<p> <p><br ><p> <p>About Kensho<p> <p><br ><p> <p>Kensho is an Artificial Intelligence company that builds solutions to uncover insights in messy and unstructured data that enable critical workflows and empower businesses to make decisions with conviction We were founded in 2013 and now serve as SampP Globals innovation hub We continue to maintain our distinct independent brand in order to best promote our breakthrough innovative culture Our team of Kenshins enjoy a dynamic and collaborative work environment that runs autonomously from SampP Global while leveraging the unparalleled breadth and depth of data and resources available as part of SampP Global As Kenshins we pride ourselves on maintaining an innovative culture that depends on diversity and inclusion<p> <p><br ><p> <p>We are an equal opportunity employer that welcomes future Kenshins with all experiences and perspectives Kensho is headquartered in Cambridge MA with an office in New York City All qualified applicants will receive consideration for employment without regard to race color religion sex sexual orientation gender identity or national origin<p> <p><p>
MuleSoft Enterprise Data Engineer
Company: Schrödinger, Inc.
Location: Cambridge
Posted Dec 24, 2023
Schrödinger is seeking a MuleSoft Enterprise Data Engineer for a temporary-to-permanent position. The role involves providing technical leadership, designing and building reusable components, and collaborating with various teams. The ideal candidate should have at least four years of relevant experience, knowledge of data warehouse technical architectures, and experience in cloud environments like GCP and BigQuery. Schrödinger offers a competitive salary, stock options, and a wide range of benefits. The company is committed to diversity and equal opportunity employment.
GMP Operations Associate
Company: Vor Bio
Location: Cambridge
Posted Feb 26, 2024
<div> <p><strong>We engineer stem cell transplants that shield healthy cells from targeted therapies<strong><p> <p>Targeted therapies work by attacking cells that express particular proteins on their surface Unfortunately both diseased and healthy cells often express the same proteins resulting in collateral damage to healthy cells<p> <p>At Vor Bio we engineer hematopoietic stem cells HSCs to lack a biologically redundant target protein then transplant these cells into the patient<p> <p>These eHSCs give rise to generations of new healthy blood cells that are effectively shielded from targeted therapies so that only the remaining cancer cells are killed We are also developing our own CART cell therapy using T cells from the same healthy donor who could potentially provide HSCs for our shielded stem cell transplant and thereby avoid issues of donormismatch We believe our CART cell therapy may enable more potent and durable responses posttransplant<p> <p>Vor Bio is aiming to cure blood cancers through our novel platform combining HSC biology genome engineering and targeted therapies to unlock treatment options previously unavailable to patients Come be a part of a passionate team striving to collaboratively develop a groundbreaking approach to cancer treatment one of medicines greatest challenges<p> <p><strong>What we value in our fellow Voracians<strong><p> <p><strong>Passion<strong> Enthusiastically driving our science toward innovative medicines<p> <p><strong>Fellowship<strong> Fostering genuine bonds of collaboration and mentorship<p> <p><strong>Humility<strong> Acting selflessly by putting the collective mission first<p> <div> <p><strong>Who we are looking for <strong><p> <p>Vor Bio is seeking a GMP Operations Associate who is an enthusiastic and driven individual to support cGMP manufacturing for clinical phase cell therapy manufacturing facility The candidate will be responsible for providing assistance in the support area for the manufacturing of Vors geneedited cell therapies and maintaining compliance of cGMPs in manufacturing areas <p> <p><strong>Key areas of responsibility<strong><p> <ul><li>Support and perform cleanroom operations such as cleaning specialized equipment restocking materials sample transfer and document management<li> <li>Work with internal and external partners to track equipment preventative maintenance and calibration events and support equipment management in a computerized maintenance management system CMMS<li> <li>Coordinate with appropriate groups Supply Chain Safety and Facilities for material management safety equipment checks and facility maintenance<li> <li>Responsible for material management in and out of the cleanrooms to support clinical production<li> <li>Responsible for waste management and working with internal partners for waste removal<li> <li>Strict adherence to current good manufacturing practices standard operating procedures and manufacturing documentation<li> <li>Must be able to lift up to 50lbs<li> <ul><p><strong>Qualifications<strong><p> <ul><li>HS diploma or BS in Biology or related field<li> <li>1 3 years of handson experience with supporting manufacturing facility<li> <li>Cell therapy production support and aseptic manufacturing technique preferred<li> <ul><p><br ><br ><p><div> <p>By becoming a team member here at Vor youll have access to competitive health dental and vision coverage as well as life insurance and short term and longterm disability insurance We value work life balance youll benefit from discretionary time off parental leave and an excellent 401k package We also offer a generous transportation stipend to commute as you wish We are conveniently located in Cambridge with easy access to public transportation and ample parking<p> <p>As an equal opportunity employer we at Vor Bio know that diversity inspires innovation inclusiveness and creativity We invite you to come as you are All applicants will be considered for employment agnostic to race age color religion sex sexual orientation gender identity national origin veteran or disability status<p> <p>Please visit our website at httpswwwvorbiocom for more information<p> <div>
Head of Commercial
Company: Vedanta Biosciences
Location: Cambridge
Posted Feb 21, 2024
Vedanta Biosciences, a late-stage biopharmaceutical company, is seeking a Head of Commercial to lead commercialization strategy and operations for their first-in-class live biotherapeutic products. The role involves partnering with the CEO and leadership team, developing a global commercialization strategy, building a commercial capability set, and leading market and company readiness activities. The ideal candidate should have 20+ years of experience in biotech or pharmaceutical industry, experience in building commercial capabilities, leading enterprise transformation, and a deep understanding of the healthcare market trends.
Lead Business Development Rep
Company: Proton.ai
Location: Cambridge
Posted Feb 25, 2024
Proton, a tech startup specializing in AI-powered CRM software for the wholesale distribution industry, is seeking a passionate and resilient Business Development Representative. The role involves cold outreach, lead qualification, and nurturing prospects to fuel the sales pipeline. The ideal candidate will have a proven track record in business development or outbound sales, excellent communication skills, and a curious, resilient, and creative mindset. Proton offers competitive salaries, company stock options, unlimited PTO, medical benefits, and more. The role is based in the greater Boston area (Kendall Square) and is a hybrid position.