Tech Jobs in Cambridge
5,798 open positions · Updated daily
Cambridge's tech scene thrives at the intersection of world‑class research institutions like MIT and Harvard, a dense network of venture capital, and a culture that nurtures startups. The city attracts talent in AI, data science, and cybersecurity, driving demand for software engineers, machine learning specialists, and product managers.
Cambridge hosts a diverse roster of tech firms—from global pharma leaders such as Gilead Sciences and Boston Scientific to cloud‑native companies like HubSpot and Wayfair. Start‑ups like Ginkgo Bioworks, Butterfly Network, and Clari focus on biotech innovation, while IBM Research and MIT Lincoln Laboratory push the frontier of quantum computing and secure communications. This mix creates opportunities across hardware, software, fintech, and biotech sectors.
While the median rent for a one‑bedroom apartment in Cambridge tops $3,000/month and the city’s overall cost index is high, salaries often exceed national averages. Transparent salary data on Job Transparency allows candidates to benchmark offers, negotiate effectively, and align compensation with the true value of living in a high‑cost market.
Commercial Leader
Company: Kytopen
Location: Cambridge
Posted Dec 09, 2023
Strong negotiation, problem-solving, and decision-making abilities. Excellent leadership, communication, and interpersonal skills. We offer competitive compensation including a 401k match and equity, comprehensive package of health benefits, and a supportive work environment that includes hybrid work schedules, flexible vacation, paid family leave, and continuing education support. Willingness to travel as needed to meet with customers, attend conferences, and collaborate with remote teams. Benefits: We are a values-driven, creative team, and we know that we’re only successful because of the talented people on our team. Prepare regular reports and presentations for the executive team and stakeholders, highlighting achievements, challenges, and recommended actions. Ability and experience presenting strategy, performance metrics, and risks to executive leadership and board of directors Ability to manage and motivate a diverse team in a fast-paced, dynamic startup environment. Analytical mindset with the ability to translate data into actionable insights, including defining and tracking critical performance metrics (KPIs). Work with finance and operations teams to develop accurate sales forecasts, budgets, and resource allocation plans. Commercial Team Management: Build, manage, and mentor a high-performing team to meet and exceed revenue targets, develop and nurture relationships with key customers and stakeholders in the industry, gather customer feedback and insights to refine product offerings, enhance customer experience, inform product development efforts, address customer concerns, resolve issues, and maintain a high level of customer satisfaction.
Senior Scientist, Human Computer Integration (HCI/HMI)
Company: Charles River Analytics
Location: Cambridge
Posted Dec 09, 2023
At Charles River, we truly value work-life balance. We offer competitive compensation plus bonuses, profit-sharing, and an attractive benefits package. PhD or Masters degree in Human Factors, Cognitive Systems Engineering, Interaction Design, or Cognitive Science (or a related field) Proven record of capturing and leading research and development contracts or grants as a Principal Investigator, Technical Lead, or Chief Engineer, or Program Manager Strong written and verbal skills and prior experience in proposal writing, customer interaction, and presentation at technical conferences U.S. You will define and direct technical work, building and maintaining strong relationships with customers, sponsors, and partners. 10+ years of hands-on experience analyzing work environments and conceiving, demonstrating, and evaluating user interfaces Domain experience in areas related to autonomous systems, intelligence analysis, or tactical aviation Experience working with DARPA, AFRL, ONR, ARL and/or IARPA or any other related government organizations Military Service or DoD work experience Technical or peer-reviewed publications in any of the above fields Strong design aesthetic and functional reasoning skills with superior attention to detail Knowledge and experience with state-of-the art machine learning algorithms and autonomy systems Why Charles River? Our benefits include 100% employer-paid medical and dental insurance as well as vision, life, and disability insurance; paid maternity/paternity leave; tuition reimbursement; monthly gym allowance; free parking; generous paid time off; and a casual environment. In this role, you will lead and grow teams of researchers, designers, and engineers to research and understand work domains and user-support requirements, develop new interface concepts, and demonstrate and evaluate interactive prototypes. How you will make a difference: Help develop and execute a research agenda in areas of Human-Systems Integration and Human-Autonomy Teaming Study, model, and understand diverse customer needs in complex systems Develop work-support solutions that build on principles of human perception, cognition, and decision making Coordinate and oversee the work of other researchers, designers, and software engineers to implement and evaluate solution concepts as part of a user-centered design process Lead technical discussions with customers and collaborators Lead and contribute to proposals, technical reports, and research publications Present work at briefings and conferences Areas to be Explored: Augmented Reality, Virtual Reality, and Multimodal Interfaces Human-Autonomy Teaming Human-Robot Interaction Adaptive and Intelligent Training Decision-Support Systems What do you need? We are also accessible by public transportation. We offer a hybrid onsite/remote (60/40) schedule with tremendous flexibility.
Director/Senior Director CMC
Company: MOMA Therapeutics
Location: Cambridge
Posted Dec 09, 2023
or equivalent) in chemistry, pharmaceutical sciences or a relevant discipline You work hard, you are kind to others, and you enjoy being a part of a collaborative team that gets stuff done in an environment where scientific data rules the day MOMA Therapeutics is an equal opportunity employer and will not discriminate against any employee or applicant on the basis of age, color, disability, gender, national origin, race, religion, sexual orientation, veteran status, or any classification protected by federal, state, or local law. Your ability to build relationships, both internally and externally, and operate in a lean environment will enable success for you and our programs. You will lead multi-disciplinary CMC teams through preclinical development, IND filings and into clinical development. MOMA’s development programs require independence and leadership in a highly dynamic environment. In this role you will… Lead small molecule CMC teams comprised of technical leads and key stakeholders Establish CMC program strategy, including key activities, timelines, and budgets, in collaboration with technical experts on your team Oversee the execution of CMC-related development and manufacturing activities at external manufacturing partners, including technology transfer and on-site management Guide the authoring of regulatory filings in terms of substance and scope Identify CMC program risks and work with the CMC team to develop contingency plans Represent the CMC function at the program level and collaborate to develop program strategies Forge close working relationships across disciplines and with external partners and consultants to advance programs through clinical development About you… You have at least 10 years of experience in small molecule CMC, including experience in an early-stage biotechnology company You have experience effectively collaborating with and managing CDMOs You have experience authoring regulatory filings including INDs You are familiar with solid oral dosage form development You have a working knowledge of regulations and guidelines for small molecule development You’ve led teams and/or projects in a dynamic fast paced environment You have explicit achievements that indicate your effectiveness You’re organized and have excellent written and verbal communication skills You understand relationships are the key component of achieving significant results You know how to make decisions independently Subject matter expertise in Drug Product or Analytical method development is a plus You have an advanced degree (MS/Ph.D. In this role, you will lead drug substance, drug product and analytical development activities, and ensure the delivery of clinical trial supplies across two small molecule programs as they enter clinical development. You will manage CMC program timelines toward key goals and maintain budget oversight for all CMC activities. Your deep technical background, combined with leadership and an ability solve scientific problems under pressure will be fundamental to operating in this role. You will collaborate with internal functions to plan and align on key objectives as development unfolds. You will partner with external organizations and consultants to execute strategically efficient development and manufacturing with an eye toward regulatory milestones.
Senior Scientist, Medicinal Chemistry
Company: MOMA Therapeutics
Location: Cambridge
Posted Dec 08, 2023
MOMA Therapeutics is an equal opportunity employer and will not discriminate against any employee or applicant on the basis of age, color, disability, gender, national origin, race, religion, sexual orientation, veteran status, or any classification protected by federal, state, or local law. You work hard, you are kind to others, and you enjoy being a part of a collaborative team that gets stuff done. You enjoy being in an environment where data drives the direction of the science. You have deep experience interpreting and integrating biochemical, cellular and ADME data and implementing medicinal chemistry strategies to advance program chemical matter through all phases of drug discovery. You have a demonstrated skill set when it comes to scientific creativity and risk taking in solving complex medicinal chemistry problems. You have experience in and love complex problem solving through in-depth analysis of data or situations. You are a self-starter with demonstrated impact in medicinal chemistry and drug discovery as evidenced by performance and accomplishment. Job Summary: We are looking for In this role you will… Devise and implement medicinal chemistry strategies to achieve project / research goals Influence the selection of critical path activities to drive project progression Build strong partnerships with outsourced synthetic chemistry at partner CROs Effectively communicate medicinal chemistry strategies, innovative ideas and results, both informally and in meetings with colleagues and research management Work collaboratively across diverse functions to achieve corporate goals About you… You have a PhD degree in organic/medicinal chemistry, and at least 5 years of drug discovery experience in a pharmaceutical/biotechnology company, or a Masters degree in organic/medicinal chemistry and at least 10 years of experience. Will be part of an experienced and resilient team that is collectively unstoppable, trusts one another, and selflessly collaborates Will work with incredible humans who are committed to the discovery of transformative medicines for patients Are needed… because patients are counting on you About MOMA Therapeutics At MOMA Therapeutics, we are motivated by a single common goal, to discover and develop innovative new medicines for patients through our singular focus: the therapeutic targeting of molecular machines. Imagine joining a company where you….
Process Engineer- Slurry and Powder Mixing
Company: 24M Technologies
Location: Cambridge
Posted Dec 12, 2023
Ability to commit to aggressive timelines and to deliver on those commitments Excellent communication skills for interaction with team members, other groups and outside suppliers Works well in a team environment with willingness to share skills and information and mentor others Highly motivated and action-oriented as demonstrated by accomplishments Coachable - is able to act on management inputs and constructive criticism Desired Skills and Experience: Experience with hopper design, pneumatic conveying, powder feeding and extrusion Deep knowledge about impact of dry handling and mixing processes on wet mixing processes Deep knowledge about slurry rheology and slurry quality control parameters Experience with very high viscosity material processing Lithium ion battery industry experience Experience with both large batch mixing and high speed continuous mixing in a low cost setting Experience with lithium ion battery electrode materials synthesis and characterization Education: Bachelor’s degree in Mechanical Engineering, Process Engineering, Chemical Engineering, or related field Additional Information Physical and Environmental Standards: Capable of working in low moisture dry room environment: Capable of working in machine shop environment and operating machinery w/proper training Capable of meeting OSHA standards for manual lifting guidelines: All your information will be kept confidential according to EEO guidelines. Leverage this insight in process development Design and run simple feasibility studies to direction find on novel processes Establish process windows, and integrate process control parameters into manufacturing Required Skills and Experience: At least 3-5 years of experience in dry and wet handling and mixing process development with small size powders Strong experience and desire to work hands-on with lab and pilot equipment. The Process Engineer reports to the Pilot line manufacturing manager. For more information, please visit www.24-m.com. Mechanically savvy Proficient with Engineering Design Software (parts, assemblies and drawings) – SolidWorks Demonstrated ability and passion to understand processes and the interaction between the material, equipment and the associated impact to product performance Demonstrated ability to design, optimize and qualify processes with data driven decisions Ability to create methods to generate data where none exist and to turn art into science by getting the numbers Thrives in a fast-paced environment. Strong interpersonal skills are required, as are a strong work ethic and an ability to flourish in a dynamic startup environment. The team member will define process needs for critical production steps and collaborate with cross functional groups to identify, screen, and develop process concepts that meet these specs. Qualifications Responsibilities: Develop novel dry and wet powder handling and mixing processes that contribute to the improvement of 24M’s pilot line production system Characterize critical material performance through experimentation and analysis. Job Description The Process Engineer will be a key member of the high performing team focused on improving the next generation high volume manufacturing powder and slurry mixing process that will connect 24M’s revolutionary product to the high growth energy storage market. Founded in 2010 and led by some of the battery industry’s foremost inventors, scientists and entrepreneurs, 24M is headquartered in Cambridge, Mass.
Sr. Scientist/Principal Scientist, Computational Chemistry
Company: MOMA Therapeutics
Location: Cambridge
Posted Dec 11, 2023
MOMA Therapeutics is an equal opportunity employer and will not discriminate against any employee or applicant on the basis of age, color, disability, gender, national origin, race, religion, sexual orientation, veteran status, or any classification protected by federal, state, or local law. You work hard, you are kind to others, and you enjoy being a part of a collaborative team that gets stuff done. Proficient in scientific programming and tool development with Python You have demonstrated understanding of all aspects of modern drug discovery including medicinal chemistry, DMPK principles, multi-parameter optimization. In-depth knowledge of quantum mechanics, QM/MM and modeling protein-protein interactions is highly preferred. You have deep experience implementing computational chemistry strategies across all stages of drug discovery including target identification, hit identification and optimization to achieve program goals. About you... You have a PhD degree in computer science, computational chemistry, or related fields with 2+ years relevant drug discovery experience in a pharmaceutical or biotechnology setting. Level will reflect experience. Provide computational chemistry solution to drug discovery programs including building and deploying tools and analyses that impact medicinal chemistry decisions on drug discovery projects, spanning target assessment, hit finding, and lead optimization. You enjoy being in an environment where scientific data rules the day. Collaborate closely with drug discovery team and other computational scientists to strategize what data to collect to populate the KnowledgeBase, address computational/informatic needs.
Classified Systems Administrator
Company: Charles River Analytics
Location: Cambridge
Posted Dec 09, 2023
Ideally, we would love to see: Vendor-specific certifications from Cisco, VMware, Microsoft, RHEL, or Dell are desired. Experience supporting engineers in software, simulations, and hardware development. We offer competitive compensation plus bonuses, profit-sharing, and an attractive benefits package. Knowledge and understanding of one or more of the following regulations: JAFAN 6/9, NISPOM, JSIG, CNSSI 1253, NIST 800-53 and NIST 800-171, and ICD 705-1. At Charles River, we truly value work-life balance Knowledge and implementation experience with security technologies and architecture, including encryption, network security, firewall configuration, and intrusion detection. 3+ years of relevant experience in a system or network administration-related role, with some experience in the following technologies: LDAP, Active Directory, WSUS, VMware, Veeam (or equivalent), Nessus, or Splunk. Experience with DoD Security Technical Implementation Guides on at least one technology platform (i.e., Windows or Linux OS, switches, printers). Strong leadership skills. Collaborate with security personnel, senior staff, and IT management of all risks impacting IT-related services, including but not limited to power outages, environmental changes, natural disasters, insider threats or deliberate acts, maintenance, or third-party vendor actions.
Head, Program Management
Company: Amylyx
Location: Cambridge
Posted Dec 10, 2023
We do not discriminate based upon race, religion, color, national origin, gender (including pregnancy, childbirth, or related medical matters), sexual orientation, gender identity, gender expression, age, status as a protected veteran, status as an individual with a disability, or other applicable legally protected characteristics. Provide input into company resource planning, project management processes, and budgets. Communicate program objectives, work plans issues, and resource needs to teams, functional departments, and senior management via routine and ad hoc meetings, minutes, and action items. If you need an accommodation, please let your Amylyx Talent Acquisition contact know. Work with project team to proactively identify risks, contingencies, and alternatives. Manage long- and short-term program activities, including schedule development, project communication, status reporting, and resource interactions. As needed, provide status reports and proposals for decision to executive management, and participate in strategic discussions regarding the program(s). Excellent written and oral communication skills; scientifically curious and demonstrated interest in understanding and sharing complex ideas relating to Amylyx's programs, technology, and clinical studies LOCATION Cambridge, Massachusetts – candidates outside Massachusetts must be willing to travel to Cambridge on a regular basis To stay connected with us, follow Amylyx Pharmaceuticals on LinkedIn. Strong preference for experience building Program Management from the ground up. 20+ years' experience in a pharmaceutical or biotechnology environment, including hands on experience in leading program management activities in early and/or full clinical development is required.
Senior Process Engineer – Powder Development
Company: 24M Technologies
Location: Cambridge
Posted Dec 12, 2023
Education: Bachelor’s degree in Materials Science and Engineering, Mechanical Engineering, Chemical Engineering, Industrial Engineering, Electrical Engineering or related field. Broad experience which also includes other processes such as mixing, extrusion, formation, etc. Creative problem solver. Excellent written and verbal communication skills for interaction with team members, other groups, and external companies. Desired Skills and Experience: Lithium-ion battery industry experience. Experience in taking a process from lab scale to pilot scale, and to high volume manufacturing. Experience with continuous processing and measurement systems. Thrives in a fast-paced environment. Demonstrated ability to design, optimize and qualify processes with data driven decisions. Working understanding of machine design principle and engineering drawing reviews.
Technical Program Manager
Company: 24M Technologies
Location: Cambridge
Posted Dec 12, 2023
The candidate will expand our project reporting focused on all technical functions within 24m including product engineering, manufacturing engineering, operations, quality, and R&D. Reporting the progress, bottlenecks, and critical issues on all internal and external projects is key. This role will report to the Senior Director, Production Launch. Qualifications Key Responsibilities Strengthen 24m’s program and project management functions to closely track, identify, and solve issues within our internal and external projects Own external partner project deliverables for all technical functions within 24m including: Advanced Manufacturing, R&D, Product, Operations, Facility Design, Quality, and Supply Chain Improve project visualization throughout the company for partner projects and internal projects Organize bi-weekly executive reviews to address key achievements and issues across all internal and external projects Lead Tiger teams to solve critical issues facing the organization Own development and maintenance of 24m’s near and long-term product roadmap Work closely with the Advanced Manufacturing team to gain an in-depth knowledge of all 24m processes Work closely with the Product Engineering and R&D teams to gain an in-depth knowledge of all 24m products, current and future Additional responsibilities as defined by manager Qualifications: 2+ years in Li-ion battery industry 5+ years technical project management, product engineering, manufacturing, or quality Strong program management skills: able to manage multiple-time sensitive projects with discretion, keep attention to detail, stay level-headed, deliver on-time results, and maintain positive relationships with all affiliated project parties and stakeholders Must maintain a lean and effective project management foundation while remaining nimble and flexible to the needs of project team members Strong leadership ability – able to lead through uncertainty Supervisory Responsibility Indirectly manage a team of cross functional technical resources to accomplish strategic goals Foster a collaborative but fast-paced work environment across all functions of 24m Additional Information Physical and Environmental Standards: Capable of working in low moisture dry room environment: Capable of working in machine shop environment and operating machinery w/proper training Capable of meeting OSHA standards for manual lifting guidelines: Able to travel domestically and internationally to support development activities with suppliers, partners, customers, etc. For more information, please visit www.24-m.com. This is a critical role to help lead 24m and its partners to revolutionizing the lithium-ion industry. Job Description The Technical Program Manager will be responsible for managing internal projects within 24m and external projects with 24m partners deploying the semi-solid manufacturing technology across the globe. Founded in 2010 and led by some of the battery industry’s foremost inventors, scientists and entrepreneurs, 24M is headquartered in Cambridge, Mass. This critical role will help to define the expansion of 24m’s program management function to enable a matrix organization focused on executing our internal projects and supporting external partners. Through strategic partnerships with industry leaders, including the Volkswagen Group, Kyocera, GPSC and FREYR, 24M has built an ecosystem to rapidly scale the SemiSolidTM platform and develop a better, cleaner energy future. (up to 25%) All your information will be kept confidential according to EEO guidelines.
Director, Senior Director Genome Engineering (Vector Genome)
Company: Voyager Therapeutics
Location: Cambridge
Posted Dec 12, 2023
Sophisticated scientific management skills and business judgment with an ability to evaluate alternatives, establish priorities, and apply resources effectively. Must be highly motivated, and will derive motivation from working in a small, entrepreneurial biotech environment, accepting the challenge of broad responsibilities and opportunities within a fast-paced, matrix-focused can-do culture. Must have intellectual and scientific curiosity and integrity; must be scientifically rigorous and creative; committed to patient-centricity, transparency, and ethical research values. Can-do team-oriented attitude which is consistent with Voyager core values. Qualifications A Ph.D. or MD/Ph.D. Enthusiasm for operating effectively within an entrepreneurial and science-driven company environment. Track record of driving innovative ways of thinking and/or innovative ways of using data. Participate in the process of selecting, prioritizing, and accelerating the development of assets. Support the continued protection, creation, and expansion of the company’s intellectual property. Responsible for interrogation of candidate sequences, and reduction-to-practice of sequences intended for clinical application, for numerous gene therapy initiatives.
Software Engineering Manager Cloud Platform
Company: Sense
Location: Cambridge
Posted Dec 12, 2023
Competitive compensation including equity Great work-life balance Flexible work hours Flexible Time Off Paid parental leave (5 weeks or more depending on location) Dependent Care Accounts Generous healthcare benefits for employees and dependents Medical (90% of the premium and first 50% of the deductible) Dental (90%) Vision (100%) Flexible Spending Accounts Life, AD&D, long- and short-term disability insurance (100%) 401k plan with company match Free Sense energy monitor for your home, discounts for friends and family Remote-friendly Remote or local/hybrid in our Cambridge Central Square office Home office setup allowance ($200/year) Great opportunity to gain experience at a consumer smart home startup. In this role, you will Lead the team in building a core cloud platform to support company objectives while managing costs and handling major increases in scale Be responsible for keeping your team of engineers engaged, happy, and productive Maintain and enrich our collaborative and inclusive work culture Collaborate closely with your team and business stakeholders within Sense to determine priorities, scope projects, refine requirements, manage resource allocation, and guide projects to successful completion Serve as technical advisor to the team - monitor technical debt, drive infrastructure and tooling investments as necessary and cultivate excellence through technical mentorship Keep the team and stakeholders aligned by frequently and proactively communicating status, risks, and tradeoffs Improve processes and help define the structure and organization of the engineering department Ensure that the engineering team is efficiently delivering quality releases that are aligned with business goals Provide regular feedback and coaching to nurture career growth Drive hiring of great candidates as the team grows This role reports to the Director of Engineering, Scale Zone. We are a team of highly curious, collaborative engineers who enjoy working together to solve a wide range of interesting technical challenges across a deep stack that spans embedded, native mobile, web, and the cloud. Requirements Strong communicator with good EQ Previous experience as an engineering manager Professional experience as a software engineer Must be authorized to work in the U.S Previous experience with startup culture and scaling is a plus Experience managing and growing cloud infrastructure is a must Benefits Be a part of building something that will make a difference in the world. If the idea of having a significant positive impact on our product (and climate) sounds exciting to you, let's talk! We're looking for an Engineering Manager to lead our Core Cloud Platform team to meet the demands of our growing user base and partner ecosystem. Our consumer product, built on our unique machine learning technology, gives people visibility into the energy usage of their homes and provides insights to simplify saving energy and money. To accomplish our mission, we are building an AI and automation platform for home energy infrastructure. We're serious about having a real impact on climate change by empowering people to easily take care of their homes and to actively participate in a cleaner, more resilient future.