Tech Jobs in SAINT LOUIS, Missouri

49,962 open positions · Updated daily

Saint Louis has become a magnet for tech talent as the city blends a strong manufacturing legacy with a growing fintech and healthcare IT scene. With 3,579 open tech roles, companies from HCA Healthcare to startup incubators in Midtown and The Block are actively hiring. The city’s business-friendly tax incentives and proximity to the Midwest’s largest transportation hub give tech professionals access to high-paying roles without the high cost of tech-centric coasts.

The region’s tech ecosystem spans healthcare IT, logistics software, fintech, and manufacturing automation. Centene’s data‑science teams, HCA’s cybersecurity engineers, and logistics giants like UPS and FedEx use local talent to power telehealth platforms and supply‑chain analytics. Startups such as Raptor Labs in the Delmar Loop and Kingfisher Labs in Forest Park focus on AI and blockchain, creating a diverse portfolio of opportunities for software engineers, product managers, and DevOps specialists.

Saint Louis offers a moderate cost of living—average rent in Tower Grove or Forest Park is around $1,200–$1,600 per month, and groceries and utilities stay below national averages. Transparent salary information lets candidates evaluate whether a $100,000 software engineering role aligns with their living expenses, especially when considering benefits, relocation packages, and the city’s robust public transportation network.

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Advanced Practitioner (PA) - Family Medicine Office in Wentzville, MO

Company: SSM Health

Location: Wentzville, Missouri

Posted Aug 15, 2025

View Details Apply on healthecareers.com

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Physician - Child Protection - Full Time Academic - SLUCare Physician Group

Company: SSM Health

Location: Saint Louis, Missouri

Posted Aug 14, 2025

View Details Apply on healthecareers.com

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Division Chief with Regional Impact - Vascular Surgeon - Top-Tier Academic Center - Saint Louis University School of Medicine

Company: SSM Health

Location: Saint Louis, Missouri

Posted Aug 14, 2025

View Details Apply on healthecareers.com

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Epilepsy Neurologist

Company: Saint Luke's Health System

Location: Kansas City, Missouri

Posted Aug 14, 2025

View Details Apply on healthecareers.com

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GI | Missouri University Town | 100% Physician Owned | 650k base | 900k Earnings

Company: Jackson Physician Search

Location: Missouri

Posted Aug 14, 2025

View Details Apply on healthecareers.com

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Academic Pediatric Orthopaedic Surgeon

Company: SSM Health

Location: Saint Louis, Missouri

Posted Aug 14, 2025

View Details Apply on healthecareers.com

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Physical Therapist Assistant - Skilled - (PTA)

Company: AMN Healthcare, Inc. Medical

Location: SAINT LOUIS, Missouri

Posted Aug 15, 2025

View Details Apply on healthecareers.com

Apprentice Plumber

Company: Kat's Plumbing Inc.

Location: Missouri City, TX

Posted Aug 14, 2025

Support field service operations by responding to service calls and performing necessary repairs. Utilize hand tools and power tools safely and effectively for…

View Details Apply on SimplyHired

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Physician - Pulmonary Medicine only - St. Mary's Hospital - Richmond Heights MO - Full Time

Company: SSM Health

Location: Saint Louis, Missouri

Posted Aug 14, 2025

View Details Apply on healthecareers.com

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Transfusion Medicine Medical Director – SLUCare Physician Group

Company: SSM Health

Location: Saint Louis, Missouri

Posted Aug 14, 2025

View Details Apply on healthecareers.com

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SSM Health Saint Louis University Hospital Inpatient Stroke Neurology Advanced Practitioner

Company: SSM Health

Location: Saint Louis, Missouri

Posted Aug 14, 2025

View Details Apply on healthecareers.com

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Urologist - (Female and General Urology)

Company: Park Nicollet

Location: St. Louis Park, Minnesota

Posted Aug 15, 2025

View Details Apply on healthecareers.com

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Frequently Asked Questions

What types of tech jobs are available in Saint Louis?

Saint Louis hosts a wide spectrum of tech roles, from software engineers (full‑stack, mobile, backend) and data scientists at Centene to cybersecurity analysts at HCA Healthcare. Product managers, UX designers, and DevOps specialists are in demand at logistics firms like UPS and FedEx, while AI/ML engineers find opportunities at startups such as Raptor Labs and Kingfisher Labs.

Are tech roles in Saint Louis remote, hybrid, or on‑site?

Most senior positions at large employers like HCA and Centene offer hybrid options, allowing employees to work from the downtown office two days a week and remotely the rest. Startups in Midtown and The Block typically require on‑site presence to foster collaboration, but many are expanding their remote talent pool due to the pandemic‑shifted culture.

Who are the major tech employers in Saint Louis?

Key employers include HCA Healthcare’s digital health division, Centene’s analytics teams, UPS and FedEx’s logistics tech hubs, Boeing’s aerospace software labs, and local innovators such as Raptor Labs, Kingfisher Labs, and Innovate St. Louis. The city also attracts national firms like Google and Microsoft through satellite offices.

What salary can I expect for tech roles in Saint Louis?

Software engineers earn between $80,000 and $110,000, with senior positions reaching $120,000+. Data scientists typically earn $90,000–$130,000, while cybersecurity experts command $95,000–$140,000. Benefits packages often include health insurance, retirement plans, and relocation stipends, which can significantly increase total compensation.

How can I relocate to Saint Louis for a tech job?

Start by researching neighborhoods: Tower Grove offers a vibrant student vibe, Delmar Loop offers boutique shopping, and Forest Park provides suburban tranquility. Many employers provide relocation assistance, including housing stipends and moving allowances. Utilize the city’s public transit (MetroLink) and bike lanes to stay connected once you arrive.

Tech Jobs in SAINT LOUIS, Missouri

Frequently Asked Questions

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