Tech Jobs in SAINT LOUIS, Missouri
Saint Louis has become a magnet for tech talent thanks to its blend of cutting‑edge research, a diverse industrial base, and a network of top universities. Companies from AI leaders like C3.ai to health‑tech innovators such as Slyce and biotech giants like Gilead Sciences are expanding their footprints, creating a steady stream of roles that blend software engineering, data science, and product management.
The city’s tech ecosystem spans several key sectors. In addition to AI and health tech, the region hosts a thriving fintech community with firms such as The Money Store and a growing number of manufacturing‑automation startups. Logistics giants like FedEx and Lumen Technologies maintain large engineering teams, while the University of Missouri‑St. Louis and Washington University drive research collaborations that feed the local talent pool.
With a cost of living about 15 % below the national average, Saint Louis offers a high quality of life without the price tag of coastal hubs. Median home prices hover around $200,000, and the average rent for a one‑bedroom apartment is roughly $1,200. Salary transparency is therefore crucial; it lets candidates compare offers against local living costs and negotiate wages that reflect the true value of their work in a city where money stretches further.
Breast Surgeon - SSM Health St. Mary's Hospital - St. Louis, MO
Company: SSM Health
Location: Richmond Heights, Missouri
Posted Oct 27, 2025
Palliative Medicine Physician - SSM Health DePaul Hospital - Bridgeton, Missouri
Company: SSM Health
Location: Bridgeton, Missouri
Posted Oct 27, 2025
Physician - Pediatric Critical Care Physician, SLUCare Physician Group - Full Time Academic
Company: SSM Health
Location: Saint Louis, Missouri
Posted Nov 02, 2025
GI Opportunity with Multiple Locations in Illinois and Michigan
Company: RosmanSearch
Location: St. Louis, Missouri
Posted Oct 27, 2025
Academic Interventional Cardiology
Company: University Health Physicians
Location: Kansas City, Missouri
Posted Oct 27, 2025
Lead Neurologist - Shape the Future of Neurology Care in Mid-Missouri
Company: SSM Health
Location: Jefferson City, Missouri
Posted Oct 27, 2025
Pediatric Division Chief of Allergy/Immunology Physician (S) (FAC) - SLUCare Physician Group
Company: SSM Health
Location: Saint Louis, Missouri
Posted Nov 02, 2025
Amazing Opportunity Ob/Gyn Physician - SSM Health Depaul Hospital
Company: SSM Health
Location: Bridgeton, Missouri
Posted Nov 02, 2025
Emergency Medicine Physician with SSM Health Saint Louis University Hospital Level 1 Trauma Center - PRN
Company: SSM Health
Location: Saint Louis, Missouri
Posted Oct 27, 2025
Orthopedic Foot and Ankle Physician
Company: SSM Health
Location: Bridgeton, Missouri
Posted Nov 03, 2025
Neurohospitalist - Saint Luke's Marion Bloch Neuroscience Institute - Kansas City, MO
Company: Saint Luke's Health System
Location: Kansas City, Missouri
Posted Nov 03, 2025
Primary Care Physician
Company: Department of Veterans Affairs
Location: Springfield, Missouri
Posted Nov 02, 2025