Tech Jobs in SAINT LOUIS, Missouri
Saint Louis has become a magnet for tech talent thanks to its blend of cutting‑edge research, a diverse industrial base, and a network of top universities. Companies from AI leaders like C3.ai to health‑tech innovators such as Slyce and biotech giants like Gilead Sciences are expanding their footprints, creating a steady stream of roles that blend software engineering, data science, and product management.
The city’s tech ecosystem spans several key sectors. In addition to AI and health tech, the region hosts a thriving fintech community with firms such as The Money Store and a growing number of manufacturing‑automation startups. Logistics giants like FedEx and Lumen Technologies maintain large engineering teams, while the University of Missouri‑St. Louis and Washington University drive research collaborations that feed the local talent pool.
With a cost of living about 15 % below the national average, Saint Louis offers a high quality of life without the price tag of coastal hubs. Median home prices hover around $200,000, and the average rent for a one‑bedroom apartment is roughly $1,200. Salary transparency is therefore crucial; it lets candidates compare offers against local living costs and negotiate wages that reflect the true value of their work in a city where money stretches further.
$325,000+ | Inpatient Child and Adolescent Psychiatry l Kansas City Metro
Company: Jackson Physician Search
Location: Missouri
Posted Oct 26, 2025
General Otolaryngologist
Company: HealthPartners
Location: Saint Croix Falls, Wisconsin
Posted Oct 25, 2025
Part-Time Family Medicine Advanced Practitioner (PA) - Des Peres, Missouri
Company: SSM Health
Location: Saint Louis, Missouri
Posted Oct 26, 2025
Academic Non-Invasive Cardiologist - SSM Health Saint Louis University Hospital
Company: SSM Health
Location: Saint Louis, Missouri
Posted Oct 26, 2025
Physician, Division Director Infectious Diseases with SSM Health Saint Louis University Hospital in St. Louis, Missouri
Company: SSM Health
Location: Saint Louis, Missouri
Posted Oct 26, 2025
GYN Heavy | 515K+ First Year Package | Brand New Facility | Missouri
Company: Jackson Physician Search
Location: Missouri
Posted Oct 25, 2025
Travel Postpartum/Mother-Baby Registered Nurse - $2,092 per week
Company: American Traveler
Location: Rolla, Missouri
Posted Oct 26, 2025
Cardiac Surgery APP with Endoscopic Vein Harvesting Experience - St. Louis
Company: SSM Health
Location: Saint Louis, Missouri
Posted Oct 25, 2025
Physician - Anesthesiology - Full Time Academic - SLUCare Physician Group
Company: SSM Health
Location: Saint Louis, Missouri
Posted Oct 26, 2025
Travel Physical Therapist - $2,355 per week
Company: Trustaff Allied
Location: Troy, Missouri
Posted Oct 26, 2025
Travel Interventional Radiology Technologist - $3,123 per week
Company: Wellspring Nurse Source
Location: Saint Augustine, Florida
Posted Oct 26, 2025
Non-Invasive Cardiologist - Fenton, MO
Company: SSM Health
Location: Saint Louis, Missouri
Posted Oct 26, 2025