Tech Jobs in SAINT LOUIS, Missouri

49,974 open positions · Updated daily

Saint Louis has become a magnet for tech talent as the city blends a strong manufacturing legacy with a growing fintech and healthcare IT scene. With 3,579 open tech roles, companies from HCA Healthcare to startup incubators in Midtown and The Block are actively hiring. The city’s business-friendly tax incentives and proximity to the Midwest’s largest transportation hub give tech professionals access to high-paying roles without the high cost of tech-centric coasts.

The region’s tech ecosystem spans healthcare IT, logistics software, fintech, and manufacturing automation. Centene’s data‑science teams, HCA’s cybersecurity engineers, and logistics giants like UPS and FedEx use local talent to power telehealth platforms and supply‑chain analytics. Startups such as Raptor Labs in the Delmar Loop and Kingfisher Labs in Forest Park focus on AI and blockchain, creating a diverse portfolio of opportunities for software engineers, product managers, and DevOps specialists.

Saint Louis offers a moderate cost of living—average rent in Tower Grove or Forest Park is around $1,200–$1,600 per month, and groceries and utilities stay below national averages. Transparent salary information lets candidates evaluate whether a $100,000 software engineering role aligns with their living expenses, especially when considering benefits, relocation packages, and the city’s robust public transportation network.

QC Scientist I

Company: Thermo Fisher Scientific

Location: St. Louis, MO

Posted Dec 04, 2024

Thermo Fisher Scientific is seeking a candidate with a Bachelor's degree in a relevant field and at least 1 year of experience in a regulated environment. The role involves using analytical tools like HPLC and UPLC for GMP manufacturing, stability testing, and developing new techniques. The candidate will work in a cGMP environment, compile data, and collaborate with team members. Key skills include in-depth knowledge of analytical techniques, MS Office proficiency, and strong organizational skills. The company offers competitive remuneration, healthcare benefits, and a positive company culture.

Territory Representative - St. Louis, Missouri

Company: Caldera Medical

Location: St. Louis, MO

Posted Dec 04, 2024

Caldera Medical is a growth-stage medical device company dedicated to improving the quality of life for women. They develop and market differentiated surgical implants for the treatment of Stress Urinary Incontinence and Pelvic Organ Prolapse. The company has been recognized as one of Inc 5000's fastest growing private companies in the US and is committed to treating 1 million women suffering from incontinence by 2025. They offer competitive compensation, comprehensive benefits, and an equal opportunity employer.

Director, Tax/Estate Strategy

Company: Edward Jones

Location: St. Louis, MO

Posted Dec 04, 2024

Edward Jones is seeking a Director of Tax & Estate Strategy to lead a team of 8 professionals, providing strategic tax and estate planning for the firm's High Net Worth clients. The role involves client-facing responsibilities, business development, and hiring decisions. The Director will also engage with third-party providers and inform systems and tools to align with the HNW business segment strategy. The ideal candidate will have a Bachelor's degree, CFP, Juris Doctorate or CPA, and 15+ years of financial services experience, including 10+ years in financial planning. They should possess deep subject matter expertise in financial planning strategies, tax and estate planning, and economic, investment, and portfolio management concepts.

Patient Care Technician

Company: DaVita

Location: Saint George, UT

Posted Dec 04, 2024

DaVita is seeking a Patient Care Technician with no dialysis experience required. They offer paid training to gain skills for patient care in an outpatient dialysis center. The role involves direct patient care, technician duties, continuous improvement, building relationships with patients, and working in a cross-functional team. The schedule can vary, including early morning shifts, weekends, and holidays. Benefits include comprehensive health care, 401k match, and opportunities for career growth through DaVita's Clinical Ladders and Bridge to Your Dreams programs.

Therapy Opportunities in SW Missouri - Physical, Occupational, & Speech

Company: Mercy

Location: Springfield, Missouri

Posted Dec 04, 2024

Shelly Francka, a Talent Scout at Mercy, invites interested individuals to explore therapy career opportunities in Physical, Occupational, and Speech Therapy. Mercy is expanding and seeks highly qualified professionals for various locations including Springfield, Lebanon, Joplin, Carthage, Aurora, Cassville, and St. Francis. The company offers full-time and PRN positions, emphasizing a supportive work environment and the chance to do more of what one loves. Mercy has classified this as a safety-sensitive position, requiring constant alertness and safe work practices.

Barista

Company: Sodexo

Location: St. Louis, MO

Posted Dec 04, 2024

Sodexo is seeking a Barista for full-time or part-time positions at Saint Louis University. The role involves creating quality beverages and food, operating cash registers, and maintaining cleanliness. Sodexo values teamwork, adaptability, reliability, and a safe working environment. They offer flexible work schedules, ongoing training, comprehensive benefits, and opportunities for career advancement. Sodexo's mission is to enhance the quality of life for those they serve and contribute to community progress.

Pharmacy Technician-Saint Paul, MN

Company: UnitedHealth Group

Location: Saint Paul, MN

Posted Dec 04, 2024

Genoa Healthcare, a part of Optum and UnitedHealth Group, is seeking a Pharmacy Technician. The role involves dispensing prescriptions, managing inventory, and providing excellent customer service. The company offers a $3,000 sign-on bonus for external applicants, competitive pay, comprehensive benefits, and opportunities for growth. The position is full-time, with hours from Monday to Friday, 8:00am-5:00pm, and rotating weekends every 7th to 10th weekend. It's located in Saint Paul, MN.

Respiratory Therapist- Gig

Company: Mercy

Location: Springfield, Missouri

Posted Dec 04, 2024

Mercy Hospital Springfield, Joplin and Surrounding Communities is offering a flexible incentivized RT position with a base rate of $30 (CRT) - $35 (RRT)/hr. The position involves performing direct patient care in all aspects of respiratory care, consulting physicians on therapy effectiveness, and acting as an advanced resource person for respiratory care. Qualifications include graduation from a CoArc approved Respiratory Care program, state licensure, RRT or CRT credential, and one year of experience. Mercy values compassion, professionalism, positive outlook, and advocacy, offering opportunities for innovation and growth in a supportive community.

Branch Office Administrator

Company: Edward Jones

Location: Saint George, UT

Posted Dec 04, 2024

Edward Jones is seeking a Branch Office Administrator (BOA) for a full-time position. The role involves working closely with Financial Advisors to help clients achieve their long-term financial goals. BOAs are valued members of the client team, with responsibilities including delivering exceptional service, participating in annual business planning, and identifying opportunities for additional services. The company offers comprehensive training, a supportive network, and competitive compensation. Benefits include medical, dental, vision coverage, disability insurance, a 401k plan, and more. The ideal candidate should have strong relationship-building skills, the ability to work independently, and proficiency in office technology.

Oral & Maxillofacial Surgery

Company: Kansas City Dental Implants and Oral Surgery

Location: Kansas City, Missouri

Posted Dec 04, 2024

A multi-location private group practice is seeking a board-certified oral and maxillofacial surgeon for an immediate partnership with a guaranteed base salary of $450,000. The opportunity includes collection, relocation, and sign-on bonuses, along with a full scope of work emphasizing dental implants. The practice values leadership, teaching skills, a strong work ethic, and willingness to learn new advancements in oral surgery.

Registered Nurse (Non-Exempt) (10013N)

Company: Mercy

Location: Saint Louis, Missouri

Posted Dec 04, 2024

Mercy South Clinical Decision Unit is offering attractive sign-on bonuses for RNs and GNs. This fast-paced unit caters to patients in observation status with anticipated stays of 24-48 hours, typically admitted from the Emergency Department. The unit requires critical thinking and quick decision-making skills, providing opportunities for ongoing education and competency training in neuro and cardiac conditions. The RN ratio is 4-5 patients with tech support, and leadership is available 24/7. Collaboration with various teams ensures efficient patient flow. Mercy offers comprehensive benefits, including health, vision, dental coverage, PTO, tuition reimbursement, and retirement funds. The company values compassion, professionalism, and a positive outlook, encouraging applicants who align with these principles.

Senior Accountant

Company: Spectrum

Location: St. Louis, MO

Posted Dec 04, 2024

Spectrum's Financial Accounting team is seeking a Senior Accountant with 4-6 years of general ledger accounting experience. The role involves preparing, analyzing, and interpreting financial statements, and ensuring compliance with SOX controls. The successful candidate will contribute to Spectrum's growth and success in the telecommunications industry by providing expert analysis and interpretation of financial data. Spectrum values individuals who are results-driven, committed to delivering exceptional results, and motivated to get things done.

Frequently Asked Questions

What types of tech jobs are available in Saint Louis?
Saint Louis hosts a wide spectrum of tech roles, from software engineers (full‑stack, mobile, backend) and data scientists at Centene to cybersecurity analysts at HCA Healthcare. Product managers, UX designers, and DevOps specialists are in demand at logistics firms like UPS and FedEx, while AI/ML engineers find opportunities at startups such as Raptor Labs and Kingfisher Labs.
Are tech roles in Saint Louis remote, hybrid, or on‑site?
Most senior positions at large employers like HCA and Centene offer hybrid options, allowing employees to work from the downtown office two days a week and remotely the rest. Startups in Midtown and The Block typically require on‑site presence to foster collaboration, but many are expanding their remote talent pool due to the pandemic‑shifted culture.
Who are the major tech employers in Saint Louis?
Key employers include HCA Healthcare’s digital health division, Centene’s analytics teams, UPS and FedEx’s logistics tech hubs, Boeing’s aerospace software labs, and local innovators such as Raptor Labs, Kingfisher Labs, and Innovate St. Louis. The city also attracts national firms like Google and Microsoft through satellite offices.
What salary can I expect for tech roles in Saint Louis?
Software engineers earn between $80,000 and $110,000, with senior positions reaching $120,000+. Data scientists typically earn $90,000–$130,000, while cybersecurity experts command $95,000–$140,000. Benefits packages often include health insurance, retirement plans, and relocation stipends, which can significantly increase total compensation.
How can I relocate to Saint Louis for a tech job?
Start by researching neighborhoods: Tower Grove offers a vibrant student vibe, Delmar Loop offers boutique shopping, and Forest Park provides suburban tranquility. Many employers provide relocation assistance, including housing stipends and moving allowances. Utilize the city’s public transit (MetroLink) and bike lanes to stay connected once you arrive.

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