Tech Jobs in SAINT LOUIS, Missouri

49,974 open positions · Updated daily

Saint Louis has become a magnet for tech talent as the city blends a strong manufacturing legacy with a growing fintech and healthcare IT scene. With 3,579 open tech roles, companies from HCA Healthcare to startup incubators in Midtown and The Block are actively hiring. The city’s business-friendly tax incentives and proximity to the Midwest’s largest transportation hub give tech professionals access to high-paying roles without the high cost of tech-centric coasts.

The region’s tech ecosystem spans healthcare IT, logistics software, fintech, and manufacturing automation. Centene’s data‑science teams, HCA’s cybersecurity engineers, and logistics giants like UPS and FedEx use local talent to power telehealth platforms and supply‑chain analytics. Startups such as Raptor Labs in the Delmar Loop and Kingfisher Labs in Forest Park focus on AI and blockchain, creating a diverse portfolio of opportunities for software engineers, product managers, and DevOps specialists.

Saint Louis offers a moderate cost of living—average rent in Tower Grove or Forest Park is around $1,200–$1,600 per month, and groceries and utilities stay below national averages. Transparent salary information lets candidates evaluate whether a $100,000 software engineering role aligns with their living expenses, especially when considering benefits, relocation packages, and the city’s robust public transportation network.

Engineer II, QA - QA Floor

Company: Thermo Fisher Scientific

Location: St. Louis, MO

Posted Dec 03, 2024

Thermo Fisher Scientific is seeking a Quality Engineer II for their St. Louis site, a biologic drug substance manufacturing facility. The role involves working closely with Manufacturing and Process Engineering to supervise activities from a quality perspective, conducting thorough audits and inspections, and ensuring compliance with industry standards and regulations. The position requires cleanroom manufacturing experience, understanding of Quality practices and cGMP regulations, and strong problem-solving skills. The job is non-supervisory, working with the Supervisor of QA Operations, and involves a 3rd Shift schedule, Sun-Wed, starting at 10PM Saturday night and ending Wednesday morning at 8:30AM.

Lead Financial Analyst

Company: Federal Reserve System

Location: St. Louis, MO

Posted Dec 03, 2024

The Federal Reserve Bank of St Louis is looking for a Lead Financial Analyst to join their division. The role involves leading budget and forecasting activities, conducting workforce monitoring, and establishing financial and budgeting processes. The bank offers a comprehensive benefits package, flexible work environment, and opportunities for growth and development.

Sr Building Maintenance Technician

Company: Thermo Fisher Scientific

Location: St. Louis, MO

Posted Dec 03, 2024

Thermo Fisher Scientific is seeking a Maintenance Technician for their Drug Substance Division in St. Louis, MO. The role involves electrical/electronic repair in a manufacturing plant, strong knowledge of PLCs, instrumentation, troubleshooting, repair, and calibration. The individual will work in a fast-paced environment, communicate effectively, and lead/participate in plant problem-solving teams. Key responsibilities include operating, maintaining, and fixing all production equipment, adhering to strict product safety & quality standards, and supporting continuous improvement programs. The company offers competitive remuneration, healthcare, and a range of employee benefits, along with an exciting company culture that values integrity, intensity, involvement, and innovation.

Customer Experience Associate - Quispamsis - Future Opportunities

Company: TD Bank

Location: Saint John, Canada

Posted Dec 03, 2024

TD Canada Trust is seeking a Customer Experience Associate in Quispamsis, New Brunswick, Canada. The role involves processing financial transactions, understanding customer needs, and recommending suitable banking solutions. The ideal candidate should have strong administration skills, knowledge of MS Office, and excellent communication abilities. TD offers competitive compensation, growth opportunities, and a supportive work environment. The job description emphasizes the importance of providing excellent customer service and contributing to a positive, diverse, and equitable work culture.

Pharmacy Technician

Company: CVS Health

Location: Missouri City, TX

Posted Dec 03, 2024

CVS Health is inviting applications for Pharmacy Technicians, emphasizing their commitment to human-centric healthcare. The role involves delivering compassionate care, managing pharmacy workstations, and ensuring regulatory compliance. New hires must complete a training program and meet state board of pharmacy requirements. The position offers opportunities for career growth and a range of benefits, including medical, dental, vision, 401(k), life insurance, disability benefits, and well-being programs.

Retail Cash Office Associate

Company: The TJX Companies, Inc.

Location: Saint Joseph, MO

Posted Dec 03, 2024

HomeGoods Store 1142 in Saint Joseph, MO is seeking a customer service-oriented individual to contribute to the growth of their career. The role involves delivering a highly satisfied customer experience, maintaining a clean and organized store environment, and adhering to all operational, merchandise, and loss prevention standards. The company culture is dynamic yet supportive, encouraging employees to 'Discover Different'. Benefits include an associate discount, 401(k) contributions, and various insurance options. The starting pay range is $12.30 to $12.80 per hour.

Pharmacy Technician

Company: CVS Health

Location: St. Louis, MO

Posted Dec 03, 2024

CVS Health is inviting applications for Pharmacy Technicians, emphasizing their commitment to delivering human-centric health care. The role involves providing compassionate care to patients, managing prescription tasks, and ensuring regulatory compliance. Successful candidates will demonstrate accountability, caring, collaboration, innovation, and integrity. The position offers opportunities for career growth and comprehensive benefits. New hires must complete a training program and meet state licensing requirements.

Pharmacy Manager

Company: CVS Health

Location: St. Louis, MO

Posted Dec 03, 2024

CVS Health is seeking a Pharmacy Manager to lead and direct pharmacy staff, ensuring patient safety, professional practice, regulatory requirements, quality assurance, customer service, personnel management, inventory management, financial profitability, and loss prevention. The role involves keeping customers and patients healthy through patient care programs, motivating and developing staff, identifying business opportunities, and driving growth. The ideal candidate will have an active pharmacy license, immunization certification, and a Bachelor's or Pharm.D. degree. The company offers competitive pay, benefits, and a supportive work environment.

Engineering Manager

Company: Leidos

Location: St. Louis, MO

Posted Dec 03, 2024

Leidos is seeking an Engineering Manager to support a large Department of Defense (DoD) customer. This role involves leading a geographically distributed team, collaborating with the Chief Engineer, Program Manager, and Deputy Program Manager. The manager will be responsible for systems requirements analysis, functional analysis, timeline analysis, trade studies, requirements allocation, interface definition, technical management, integration, system testing, and quality assurance. The ideal candidate should have experience in resolving complex problems, developing innovative solutions, and managing IT System Engineers. Leidos offers opportunities for career development and work-life balance. The role requires a Bachelor's degree in a related technical discipline, 12+ years of related engineering experience, and DoD 8570.11- IAT Level II certification.

Pharmacy Technician - St Louis Lobby Pharmacy, Full-time

Company: Mercy

Location: Creve Coeur, Missouri

Posted Dec 03, 2024

Mercy Hospital St Louis is seeking a Pharmacy Technician. The role involves assisting pharmacists in preparing, compounding, and dispensing medications. Mercy values careers that align with individual skills and hearts, offering great benefits including health, vision, and dental coverage, PTO, tuition reimbursement, and retirement funds. Mercy is known for its compassionate care and innovative procedures, fostering a supportive community. The ideal candidate should have a positive outlook, strong advocacy, and be willing to go the extra mile for excellent care.

Manager, Dental Contract Negotiator

Company: CVS Health

Location: Saint Paul, MN

Posted Dec 03, 2024

CVS Health is seeking a candidate with extensive health or dental insurance experience for a role focused on dental provider recruitment and contracting. The position involves leading regional ground campaigns, developing best practices for provider negotiations, and improving provider experience. The ideal candidate should possess strong analytical skills, knowledge of dental provider and group contracting, and proficiency in Microsoft Office products, Salesforce, and Teams. A bachelor's degree is preferred, and leadership experience is a plus. The company offers competitive compensation, comprehensive benefits, and opportunities for professional growth.

Onsite Services Crib Associate (Full Time)

Company: Grainger

Location: St. Louis, MO

Posted Dec 03, 2024

Grainger, a leading industrial distributor, is seeking a passionate Onsite Services Crib Associate. The role involves warehouse and inventory management, order processing, and maintaining a clean work environment. Grainger offers competitive benefits including medical, dental, vision, life insurance, generous paid time off, and a 401(k) plan. The company is committed to equal employment opportunity and fostering an inclusive environment.

Frequently Asked Questions

What types of tech jobs are available in Saint Louis?
Saint Louis hosts a wide spectrum of tech roles, from software engineers (full‑stack, mobile, backend) and data scientists at Centene to cybersecurity analysts at HCA Healthcare. Product managers, UX designers, and DevOps specialists are in demand at logistics firms like UPS and FedEx, while AI/ML engineers find opportunities at startups such as Raptor Labs and Kingfisher Labs.
Are tech roles in Saint Louis remote, hybrid, or on‑site?
Most senior positions at large employers like HCA and Centene offer hybrid options, allowing employees to work from the downtown office two days a week and remotely the rest. Startups in Midtown and The Block typically require on‑site presence to foster collaboration, but many are expanding their remote talent pool due to the pandemic‑shifted culture.
Who are the major tech employers in Saint Louis?
Key employers include HCA Healthcare’s digital health division, Centene’s analytics teams, UPS and FedEx’s logistics tech hubs, Boeing’s aerospace software labs, and local innovators such as Raptor Labs, Kingfisher Labs, and Innovate St. Louis. The city also attracts national firms like Google and Microsoft through satellite offices.
What salary can I expect for tech roles in Saint Louis?
Software engineers earn between $80,000 and $110,000, with senior positions reaching $120,000+. Data scientists typically earn $90,000–$130,000, while cybersecurity experts command $95,000–$140,000. Benefits packages often include health insurance, retirement plans, and relocation stipends, which can significantly increase total compensation.
How can I relocate to Saint Louis for a tech job?
Start by researching neighborhoods: Tower Grove offers a vibrant student vibe, Delmar Loop offers boutique shopping, and Forest Park provides suburban tranquility. Many employers provide relocation assistance, including housing stipends and moving allowances. Utilize the city’s public transit (MetroLink) and bike lanes to stay connected once you arrive.

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