Tech Jobs in SAINT LOUIS, Missouri

49,974 open positions · Updated daily

Saint Louis has become a magnet for tech talent as the city blends a strong manufacturing legacy with a growing fintech and healthcare IT scene. With 3,579 open tech roles, companies from HCA Healthcare to startup incubators in Midtown and The Block are actively hiring. The city’s business-friendly tax incentives and proximity to the Midwest’s largest transportation hub give tech professionals access to high-paying roles without the high cost of tech-centric coasts.

The region’s tech ecosystem spans healthcare IT, logistics software, fintech, and manufacturing automation. Centene’s data‑science teams, HCA’s cybersecurity engineers, and logistics giants like UPS and FedEx use local talent to power telehealth platforms and supply‑chain analytics. Startups such as Raptor Labs in the Delmar Loop and Kingfisher Labs in Forest Park focus on AI and blockchain, creating a diverse portfolio of opportunities for software engineers, product managers, and DevOps specialists.

Saint Louis offers a moderate cost of living—average rent in Tower Grove or Forest Park is around $1,200–$1,600 per month, and groceries and utilities stay below national averages. Transparent salary information lets candidates evaluate whether a $100,000 software engineering role aligns with their living expenses, especially when considering benefits, relocation packages, and the city’s robust public transportation network.

Physical Therapy Assistant -Full Time-Mercy Mountain View

Company: Mercy

Location: Mountain View, Missouri

Posted Nov 20, 2024

Mercy is a healthcare organization that values compassionate care and exceptional service. They offer careers that align with individual skills and heart, and have been recognized as a 'Top 100 Place to Work' by Modern Healthcare Magazine. The Physical Therapist Assistant role involves administering therapeutic modalities, assisting in medical records, maintaining department appearance, and supporting department functioning. Qualifications include an Associate's degree, current Physical Therapist Assistant license, and American Heart Association Health Care Provider Basic Life Support Certification. Mercy provides comprehensive benefits including health, vision, dental coverage, PTO, tuition reimbursement, and employer-matched retirement funds. They promote a supportive community, innovation, and are committed to delivering excellent care.

Cyber Systems Operations

Company: Uline, Inc.

Location: St. Louis, MO

Posted Nov 20, 2024

The Air Force emphasizes the importance of securing advanced computer and software systems, which is the role of Cyber Systems Operations specialists. These experts design, install, and maintain systems to ensure optimal operation and security. They enhance capabilities and provide secure systems. To join the Air Force, one must meet various requirements including educational background, health standards, and ASVAB score requirements. High school seniors can start their application during their junior year.

SAS in Schnucks - Part Time Retail Merchandiser

Company: Uline, Inc.

Location: St. Louis, MO

Posted Nov 20, 2024

SAS Retail Services is seeking a Reset Merchandiser. The role involves handling product movement at retail, ensuring the latest products match the new plan. The company offers a competitive wage of $15.00 per hour, growth opportunities, and benefits that can be customized to meet family needs. The ideal candidate is detail-oriented, physically capable of lifting up to 25lbs, and has reliable transportation.

Manager - Dierbergs Retail Pharmacy/Fenton Crossing - FT

Company: Mercy

Location: Fenton, Missouri

Posted Nov 20, 2024

Mercy is seeking a Retail Pharmacy Services Coordinator with 3 years of experience in ambulatory/retail pharmacy and management. The role involves coordinating services across 80 locations, ensuring compliance with regulations, identifying drug-related problems, and designing pharmaceutical protocols. The candidate will also manage systems for desirable patient outcomes, meet productivity and financial goals, and support a compliant 340B drug program. Mercy offers great benefits including health, vision, dental coverage, PTO, tuition reimbursement, and retirement funds. Mercy values compassion, professionalism, a positive outlook, and advocacy, and encourages applicants who align with these values.

CT Technologist - PRN - Carthage

Company: Mercy

Location: Carthage, Missouri

Posted Nov 20, 2024

Mercy is a healthcare organization that values compassionate care and exceptional service. They offer careers that align with individual skills and heart, having been named one of 'Top 100 Places to Work' by Modern Healthcare Magazine. Responsibilities include interpreting orders, producing CT images, and ensuring safety standards. Required qualifications include Radiologic Technology training, ARRT registration, and adherence to Mercy's values. Benefits include comprehensive health coverage, PTO, tuition reimbursement, and retirement funds. Mercy seeks compassionate, professional individuals with a positive outlook and a commitment to excellent care.

Phys Therapist-Home Care Svc

Company: Mercy

Location: Festus, Missouri

Posted Nov 20, 2024

Mercy is a healthcare organization that values compassionate care and exceptional service. They offer careers tailored to individual skills and talents, with a focus on work-life balance. The role involves providing in-home physical therapy services to patients with neuro and musculoskeletal disorders. Mercy prioritizes employee well-being, offering comprehensive benefits, opportunities for professional growth, and a supportive community. They seek candidates with a positive outlook, strong advocacy, and a collaborative spirit.

Senior Staff Product Security Engineer (SSDL)

Company: ServiceNow

Location: St. Louis, MO

Posted Nov 20, 2024

ServiceNow is a company that values innovation, inclusivity, and employee well-being. They are committed to creating a positive work environment and offer a range of benefits and opportunities for growth. The company is looking for a Senior Staff Product Security Engineer to join their Security Organization, which delivers world-class security solutions to reduce risk and protect customers.

Principal Scientist, MS&T

Company: Catalent, Inc.

Location: Minneapolis–Saint Paul, MN

Posted Nov 20, 2024

Catalent is a global company that develops and manufactures new treatments for patients worldwide. The Principal Scientist role involves technical transfer of processes, drafting documentation, and providing on-call technical support.

Nurse Manager

Company: Lee Company

Location: Missouri City, TX

Posted Nov 20, 2024

Encompass Health offers a Nurse Manager position with a competitive salary range of $107,868.80 - $125,424 annually, based on experience and certifications. Benefits include affordable medical, dental, and vision plans, generous paid time off, tuition reimbursement, and a company-matching 401(k). The role involves supervising nursing care, ensuring patient care activities are completed, and assigning appropriate nursing personnel. Encompass Health values empathy, positive focus, and teamwork, and has been recognized as a 'World's Most Admired Company' and a 'Fortune 100 Best Companies to Work For.'

Full Stack and Firmware Engineer

Company: Dojo Five

Location: Minneapolis–Saint Paul, MN

Posted Nov 20, 2024

Dojo Five is a dynamic startup looking for a Full Stack and Firmware Engineer to join their team. The company offers a remote work environment, generous PTO, and competitive salary and benefits.

Site Reliability Analyst II

Company: Federal Reserve System

Location: St. Louis, MO

Posted Nov 20, 2024

The job posting is for a technical support role at the Federal Reserve Bank of St Louis. The job involves providing technical support for business operations and application development lifecycle, troubleshooting complex system issues, and working with federal agencies and vendors to resolve complex application and interface issues.

Procurement Specialist

Company: Catalent, Inc.

Location: Minneapolis–Saint Paul, MN

Posted Nov 20, 2024

Catalent is hiring a Procurement Specialist to support their procurement team in Bloomington, Indiana. The role involves strategic sourcing, cost savings, and supplier management. The company offers a range of benefits, including medical, dental, and vision insurance, as well as opportunities for career growth and professional development.

Frequently Asked Questions

What types of tech jobs are available in Saint Louis?
Saint Louis hosts a wide spectrum of tech roles, from software engineers (full‑stack, mobile, backend) and data scientists at Centene to cybersecurity analysts at HCA Healthcare. Product managers, UX designers, and DevOps specialists are in demand at logistics firms like UPS and FedEx, while AI/ML engineers find opportunities at startups such as Raptor Labs and Kingfisher Labs.
Are tech roles in Saint Louis remote, hybrid, or on‑site?
Most senior positions at large employers like HCA and Centene offer hybrid options, allowing employees to work from the downtown office two days a week and remotely the rest. Startups in Midtown and The Block typically require on‑site presence to foster collaboration, but many are expanding their remote talent pool due to the pandemic‑shifted culture.
Who are the major tech employers in Saint Louis?
Key employers include HCA Healthcare’s digital health division, Centene’s analytics teams, UPS and FedEx’s logistics tech hubs, Boeing’s aerospace software labs, and local innovators such as Raptor Labs, Kingfisher Labs, and Innovate St. Louis. The city also attracts national firms like Google and Microsoft through satellite offices.
What salary can I expect for tech roles in Saint Louis?
Software engineers earn between $80,000 and $110,000, with senior positions reaching $120,000+. Data scientists typically earn $90,000–$130,000, while cybersecurity experts command $95,000–$140,000. Benefits packages often include health insurance, retirement plans, and relocation stipends, which can significantly increase total compensation.
How can I relocate to Saint Louis for a tech job?
Start by researching neighborhoods: Tower Grove offers a vibrant student vibe, Delmar Loop offers boutique shopping, and Forest Park provides suburban tranquility. Many employers provide relocation assistance, including housing stipends and moving allowances. Utilize the city’s public transit (MetroLink) and bike lanes to stay connected once you arrive.

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