Tech Jobs in SAINT LOUIS, Missouri

49,962 open positions · Updated daily

Saint Louis has become a magnet for tech talent as the city blends a strong manufacturing legacy with a growing fintech and healthcare IT scene. With 3,579 open tech roles, companies from HCA Healthcare to startup incubators in Midtown and The Block are actively hiring. The city’s business-friendly tax incentives and proximity to the Midwest’s largest transportation hub give tech professionals access to high-paying roles without the high cost of tech-centric coasts.

The region’s tech ecosystem spans healthcare IT, logistics software, fintech, and manufacturing automation. Centene’s data‑science teams, HCA’s cybersecurity engineers, and logistics giants like UPS and FedEx use local talent to power telehealth platforms and supply‑chain analytics. Startups such as Raptor Labs in the Delmar Loop and Kingfisher Labs in Forest Park focus on AI and blockchain, creating a diverse portfolio of opportunities for software engineers, product managers, and DevOps specialists.

Saint Louis offers a moderate cost of living—average rent in Tower Grove or Forest Park is around $1,200–$1,600 per month, and groceries and utilities stay below national averages. Transparent salary information lets candidates evaluate whether a $100,000 software engineering role aligns with their living expenses, especially when considering benefits, relocation packages, and the city’s robust public transportation network.

full time prn health system

Therapy Opportunities St. Louis Communities - Physical, Occupational, & Speech Therapists

Company: Mercy

Location: Saint Louis, Missouri

Posted Jun 02, 2025

View Details Apply on healthecareers.com

Owner Operator/Delivery Driver

Company: Exclusive Furniture

Location: Missouri City, TX

Posted Jun 05, 2025

Valid professional driver’s license. Good driving record with no traffic violations. We are looking for a responsible Box Truck Delivery Driver to distribute…

View Details Apply on SimplyHired
401(k) 403(b) disability insurance

Biomed II Tech

Company: BJC HealthCare

Location: Florissant, Missouri

Posted Jun 02, 2025

View Details Apply on healthecareers.com
401(k) 403(b) 457(b)

CRNA at Missouri Baptist Medical Center - New Minimal Call!

Company: BJC HealthCare

Location: Saint Louis, Missouri

Posted Jun 02, 2025

View Details Apply on healthecareers.com
dental insurance health insurance tuition reimbursement

Physical Therapist

Company: Mercy

Location: Saint Louis, Missouri

Posted Jun 08, 2025

View Details Apply on healthecareers.com
401(k) dental insurance life insurance

Nursing Opportunities Mercy Hospital Aurora / Cassville - GNs, RNs

Company: Mercy

Location: Cassville, Missouri

Posted Jun 02, 2025

View Details Apply on healthecareers.com
401(k) 403(b) dental insurance

Senior Patient Service Representative - Internal Medicine

Company: BJC HealthCare

Location: Saint Louis, Missouri

Posted Jun 02, 2025

View Details Apply on healthecareers.com
401(k) 403(b) dental insurance

Radiation Therapist - External Beam

Company: BJC HealthCare

Location: Saint Louis, Missouri

Posted Jun 02, 2025

View Details Apply on healthecareers.com
hospital part time

PCA - Patient Care Associate - Part Time - Nights

Company: Mercy

Location: Washington, Missouri

Posted Jun 08, 2025

View Details Apply on healthecareers.com
dental insurance health insurance tuition reimbursement

Respiratory Equipment Tech - Mercy Springfield - Part Time Day Shift

Company: Mercy

Location: Springfield, Missouri

Posted Jun 02, 2025

View Details Apply on healthecareers.com
loan forgiveness loan repayment program paid time off

RN- Med/Surg 7B Career Path to ER

Company: Mercy

Location: Springfield, Missouri

Posted Jun 02, 2025

View Details Apply on healthecareers.com
loan repayment program tuition reimbursement hospital

CT Technologist Full-time Nights

Company: Mercy

Location: Saint Louis, Missouri

Posted Jun 08, 2025

View Details Apply on healthecareers.com

Frequently Asked Questions

What types of tech jobs are available in Saint Louis?
Saint Louis hosts a wide spectrum of tech roles, from software engineers (full‑stack, mobile, backend) and data scientists at Centene to cybersecurity analysts at HCA Healthcare. Product managers, UX designers, and DevOps specialists are in demand at logistics firms like UPS and FedEx, while AI/ML engineers find opportunities at startups such as Raptor Labs and Kingfisher Labs.
Are tech roles in Saint Louis remote, hybrid, or on‑site?
Most senior positions at large employers like HCA and Centene offer hybrid options, allowing employees to work from the downtown office two days a week and remotely the rest. Startups in Midtown and The Block typically require on‑site presence to foster collaboration, but many are expanding their remote talent pool due to the pandemic‑shifted culture.
Who are the major tech employers in Saint Louis?
Key employers include HCA Healthcare’s digital health division, Centene’s analytics teams, UPS and FedEx’s logistics tech hubs, Boeing’s aerospace software labs, and local innovators such as Raptor Labs, Kingfisher Labs, and Innovate St. Louis. The city also attracts national firms like Google and Microsoft through satellite offices.
What salary can I expect for tech roles in Saint Louis?
Software engineers earn between $80,000 and $110,000, with senior positions reaching $120,000+. Data scientists typically earn $90,000–$130,000, while cybersecurity experts command $95,000–$140,000. Benefits packages often include health insurance, retirement plans, and relocation stipends, which can significantly increase total compensation.
How can I relocate to Saint Louis for a tech job?
Start by researching neighborhoods: Tower Grove offers a vibrant student vibe, Delmar Loop offers boutique shopping, and Forest Park provides suburban tranquility. Many employers provide relocation assistance, including housing stipends and moving allowances. Utilize the city’s public transit (MetroLink) and bike lanes to stay connected once you arrive.

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