Tech Jobs in SAINT LOUIS, Missouri

49,974 open positions · Updated daily

Saint Louis has become a magnet for tech talent as the city blends a strong manufacturing legacy with a growing fintech and healthcare IT scene. With 3,579 open tech roles, companies from HCA Healthcare to startup incubators in Midtown and The Block are actively hiring. The city’s business-friendly tax incentives and proximity to the Midwest’s largest transportation hub give tech professionals access to high-paying roles without the high cost of tech-centric coasts.

The region’s tech ecosystem spans healthcare IT, logistics software, fintech, and manufacturing automation. Centene’s data‑science teams, HCA’s cybersecurity engineers, and logistics giants like UPS and FedEx use local talent to power telehealth platforms and supply‑chain analytics. Startups such as Raptor Labs in the Delmar Loop and Kingfisher Labs in Forest Park focus on AI and blockchain, creating a diverse portfolio of opportunities for software engineers, product managers, and DevOps specialists.

Saint Louis offers a moderate cost of living—average rent in Tower Grove or Forest Park is around $1,200–$1,600 per month, and groceries and utilities stay below national averages. Transparent salary information lets candidates evaluate whether a $100,000 software engineering role aligns with their living expenses, especially when considering benefits, relocation packages, and the city’s robust public transportation network.

Sr. Instructor - GIS

Company: Esri

Location: St. Louis, MO

Posted Nov 19, 2024

As an Esri Instructor, you will leverage your teaching skills and GIS knowledge to empower customers with innovative GIS software. You will create a dynamic learning environment through hands-on training, interactive instructions, and engaging activities. Your responsibilities include growing user skills, developing and delivering training programs, identifying and addressing skill gaps, providing ongoing support, staying updated on GIS trends, ensuring sustainable GIS workflows, expanding ArcGIS use, and communicating the strategic impact of GIS programs. Requirements include 5+ years of professional experience with Esri software, 2 years of classroom facilitation, strong collaboration skills, excellent communication, and a Bachelor's degree in a relevant field. Recommended qualifications include a Master's degree, familiarity with web-based meeting tools, Esri technical and facilitation certifications, and technical writing ability.

CAAS - Assistant Controller (Nonprofit Industry)

Company: CLA (CliftonLarsonAllen)

Location: Minneapolis–Saint Paul, MN

Posted Nov 19, 2024

The job posting is for an Assistant Controller position in the CAAS practice of CLA, a top 10 national firm. The role involves providing accounting services to nonprofit clients, analyzing financial information, and preparing financial reports. The job requires 4 years of experience as a senior accountant or equivalent, and offers flexible PTO, paid parental leave, and other benefits.

Senior Manager - Behavioral Science

Company: Edward Jones

Location: St. Louis, MO

Posted Nov 19, 2024

Edward Jones is seeking a Senior Manager to lead a team of behavioral scientists. The role involves providing behavioral insights for complex initiatives, partnering with senior leaders, and influencing business decisions with behavioral science. The company values collaboration, autonomy, and growth, offering a comprehensive benefits package. The ideal candidate has 10+ years of relevant experience, a master's degree preferred, and strong leadership, problem-solving, and interpersonal skills.

Otolaryngology NP

Company: Park Nicollet

Location: St. Louis Park, Minnesota

Posted Nov 19, 2024

Park Nicollet Clinic is seeking a full-time Certified NP for their growing Otolaryngology practice. The position involves managing patients independently and in conjunction with surgeons, performing procedures with oversight, and working in both outpatient and inpatient settings. Previous ENT experience is preferred but not required. The ideal candidate should be flexible, have excellent people skills, and work well independently and as part of a team. Benefits include medical insurance, 401k with company contribution, CME reimbursement, and more. The clinic is located in the thriving area of St. Louis Park, offering walkable neighborhoods, parks, and proximity to downtown Minneapolis.

RN - OR Ortho Hospital (PRN Days)

Company: Mercy

Location: Ozark, Missouri

Posted Nov 19, 2024

Mercy is a healthcare organization that values compassionate care and exceptional service. They offer rewarding careers that align with individual skills and heart. The RN position involves utilizing the nursing process, maintaining professional accountability, and coordinating patient care. Mercy provides comprehensive benefits including health, vision, dental coverage, PTO, tuition reimbursement, and retirement funds. They encourage applicants who are compassionate, professional, positive, and advocates for excellent care.

Physician- Emergency Medicine at St. Louis University Hospital Level 1 Trauma Center - PRN

Company: SSM Health

Location: Saint Louis, Missouri

Posted Nov 19, 2024

SSM Health Saint Louis University Hospital, a Level 1 Trauma Center, is recruiting for PRN Emergency Medicine Physicians. The hospital treats nearly 50,000 patients annually, including over 3,500 trauma patients in its Emergency Department. The role involves diagnosing and treating various medical conditions, collaborating with multidisciplinary teams, and benefiting from a comprehensive compensation package including medical, dental, vision, and pharmacy benefits, pre-tax savings incentives, a wellness program, and retirement plans. The St. Louis metro area offers a rich history, cultural attractions, and excellent schools.

Pro Sales Manager

Company: Lowe's Home Improvement

Location: St. Louis, MO

Posted Nov 19, 2024

The role of a Pro Sales Manager at Lowe's involves driving sales for the company's largest regional pro customers, surpassing the general pro customer sales rate. This is achieved by building relationships with larger Pro customers, deploying product and account management solutions, and attending tradeshows. Key responsibilities include conducting market research, cold calling, meeting clients, scheduling regular visits to worksites, negotiating pricing and contract terms, and creating effective strategies for assigned accounts. The ideal candidate should have a Bachelor's Degree in Business or related field and 4+ years of relevant sales experience, or 8+ years in lieu of a degree. Strong communication skills, working knowledge of Microsoft Office, and experience with CRM technology are required. Preferred qualifications include sales experience in the MRO, construction, or home improvement industry.

Outside Account Executive

Company: DoorDash

Location: Saint Paul, MN

Posted Nov 19, 2024

DoorDash's Outside Sales team is seeking a Merchant Lead to establish partnerships with top local merchants across the country. The role involves partnering with integral merchants, mastering DoorDash's service offerings, leading negotiations, and collaborating with multiple teams. The ideal candidate has 3+ years of experience in closing sales roles, excels in strategic deal cycles, and is comfortable with ambiguity. DoorDash is committed to diversity and inclusion, and values a workforce with varied backgrounds and perspectives.

Project Manager 2

Company: Cornerstone Building Brands

Location: Minneapolis–Saint Paul, MN

Posted Nov 19, 2024

The job description outlines the responsibilities of a Project Manager 2, including facilitating quality and accurate quotations, providing efficient processing of orders, and communicating with customers and builders. The role requires a mastery of technical projects, effective communication, and the ability to work with other departments to exceed customer expectations.

Account Partner - Medtech CRO

Company: Veeva

Location: Minneapolis–Saint Paul, MN

Posted Nov 19, 2024

Veeva Systems is a mission-driven organization that helps life sciences companies bring therapies to patients faster. They are seeking an Account Partner to sell Vault RampD Solutions to Medtech divisions within the worlds leading CROs.

Principal Instructor- Defense/Intel

Company: Esri

Location: St. Louis, MO

Posted Nov 19, 2024

As an Esri Instructor, you will leverage your teaching skills and GIS knowledge to empower customers with innovative GIS software. You will create a dynamic learning environment through hands-on training, interactive instructions, and engaging activities. Your responsibilities include growing user skills, developing and delivering training programs, identifying and addressing skill gaps, providing ongoing support, staying updated on GIS trends, ensuring sustainable GIS workflows, expanding ArcGIS use, communicating GIS impact, and collaborating with stakeholders. Requirements include 8+ years of professional experience with Esri software, 5 years in defense and intelligence, 2+ years in classroom facilitation, strong communication skills, US citizenship, and willingness to obtain a security clearance. Esri offers competitive total rewards, including health benefits, 401(k), vacation leave, and opportunities for growth.

Physician - Family Medicine

Company: SSM Health

Location: Jefferson City, Missouri

Posted Nov 19, 2024

SSM Health St. Mary's Hospital in Jefferson City, MO, is seeking a board-certified Family Medicine Physician to join their well-established clinic. The position offers a 4-day work week, loan repayment program, sign-on bonus, competitive salary, and comprehensive benefits. The hospital, located in Missouri's state capital, is a full-service facility with a rich history and state-of-the-art building. It provides exceptional care in various services including emergency, cardiology, orthopedic, cancer, maternity, and medical imaging. The location offers a blend of urban and rural living with vibrant communities, historical sites, and natural wonders like the Lake of the Ozarks.

Frequently Asked Questions

What types of tech jobs are available in Saint Louis?
Saint Louis hosts a wide spectrum of tech roles, from software engineers (full‑stack, mobile, backend) and data scientists at Centene to cybersecurity analysts at HCA Healthcare. Product managers, UX designers, and DevOps specialists are in demand at logistics firms like UPS and FedEx, while AI/ML engineers find opportunities at startups such as Raptor Labs and Kingfisher Labs.
Are tech roles in Saint Louis remote, hybrid, or on‑site?
Most senior positions at large employers like HCA and Centene offer hybrid options, allowing employees to work from the downtown office two days a week and remotely the rest. Startups in Midtown and The Block typically require on‑site presence to foster collaboration, but many are expanding their remote talent pool due to the pandemic‑shifted culture.
Who are the major tech employers in Saint Louis?
Key employers include HCA Healthcare’s digital health division, Centene’s analytics teams, UPS and FedEx’s logistics tech hubs, Boeing’s aerospace software labs, and local innovators such as Raptor Labs, Kingfisher Labs, and Innovate St. Louis. The city also attracts national firms like Google and Microsoft through satellite offices.
What salary can I expect for tech roles in Saint Louis?
Software engineers earn between $80,000 and $110,000, with senior positions reaching $120,000+. Data scientists typically earn $90,000–$130,000, while cybersecurity experts command $95,000–$140,000. Benefits packages often include health insurance, retirement plans, and relocation stipends, which can significantly increase total compensation.
How can I relocate to Saint Louis for a tech job?
Start by researching neighborhoods: Tower Grove offers a vibrant student vibe, Delmar Loop offers boutique shopping, and Forest Park provides suburban tranquility. Many employers provide relocation assistance, including housing stipends and moving allowances. Utilize the city’s public transit (MetroLink) and bike lanes to stay connected once you arrive.

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