Tech Jobs in SAINT LOUIS, Missouri

49,974 open positions · Updated daily

Saint Louis has become a magnet for tech talent as the city blends a strong manufacturing legacy with a growing fintech and healthcare IT scene. With 3,579 open tech roles, companies from HCA Healthcare to startup incubators in Midtown and The Block are actively hiring. The city’s business-friendly tax incentives and proximity to the Midwest’s largest transportation hub give tech professionals access to high-paying roles without the high cost of tech-centric coasts.

The region’s tech ecosystem spans healthcare IT, logistics software, fintech, and manufacturing automation. Centene’s data‑science teams, HCA’s cybersecurity engineers, and logistics giants like UPS and FedEx use local talent to power telehealth platforms and supply‑chain analytics. Startups such as Raptor Labs in the Delmar Loop and Kingfisher Labs in Forest Park focus on AI and blockchain, creating a diverse portfolio of opportunities for software engineers, product managers, and DevOps specialists.

Saint Louis offers a moderate cost of living—average rent in Tower Grove or Forest Park is around $1,200–$1,600 per month, and groceries and utilities stay below national averages. Transparent salary information lets candidates evaluate whether a $100,000 software engineering role aligns with their living expenses, especially when considering benefits, relocation packages, and the city’s robust public transportation network.

Supervisor, Program Management

Company: EVERSANA

Location: St. Louis, MO

Posted Nov 18, 2024

The company EVERSANA is proud to be certified as a Great Place to Work and is committed to creating a healthier world. They have a global team of over 7000 employees and serve more than 650 clients. The company values diversity and inclusion and is committed to providing competitive salaries and benefits.

Electrophysiologist Is Needed for Locum Tenens Coverage in MO WBY# JOB-2998809

Company: Weatherby Healthcare

Location: St. Louis, Missouri

Posted Nov 18, 2024

Weatherby Healthcare is offering a custom career plan in EP Cardiology in St. Louis, Missouri. The position involves working with 10-15 patients per day, performing inpatient, outpatient procedures, and device implants. The company provides competitive compensation, paid malpractice insurance, pre-paid travel and housing expenses, and 24-hour access to a consultant. Weatherby Healthcare, founded in 1995, is a leading expert in locum tenens staffing for healthcare professionals.

Family Medicine Physician with OB opening in MO'

Company: Archway Physician Recruitment

Location: Nevada, Missouri

Posted Nov 18, 2024

A Family Medicine Physician with OB position is available in Nevada, Missouri. The group is seeking a dedicated professional to join their team. The hospital facilities include a 71-bed acute-care hospital, a 24-hour emergency department, a long-term care center, and an Alzheimer's care center. The community offers a low cost of living, top-notch education, and ample outdoor activities. Nevada was recognized by 417 Magazine as a Top Ten Best Community to Live due to its green space amenities.

Program Management Lead

Company: EVERSANA

Location: St. Louis, MO

Posted Nov 18, 2024

The company EVERSANA is proud to be certified as a Great Place to Work and is committed to creating a healthier world. They have a global team of over 7000 employees and serve more than 650 clients. The company values diversity and inclusion and is committed to hiring and retaining a diverse workforce.

Facility in Missouri Seeks a Locum Tenens Dermatologist WBY# JOB-2997977

Company: Weatherby Healthcare

Location: Missouri

Posted Nov 18, 2024

Weatherby Healthcare is a leading expert in locum tenens staffing for physicians, physician assistants, and nurse practitioners. The company has established itself as a trusted partner for top healthcare providers nationwide. With nearly 600 employees, Weatherby Healthcare offers competitive compensation, 24-hour access to consultants, and charter membership in NALTO.

Senior Portfolio Manager- Trust

Company: Edward Jones

Location: St. Louis, MO

Posted Nov 18, 2024

Edward Jones is seeking a Senior Portfolio Manager with a passion for portfolio management and experience in the trust or estate industry. The role involves consulting with financial advisors, clients, and other professionals to review and assess client needs, identify asset allocations, and construct portfolios aligning with client objectives. The manager will communicate account performance and changes to both financial advisors and clients. The position offers work-life flexibility and a competitive compensation package, including medical benefits, a 401k plan, and paid holidays. The ideal candidate will have a Bachelor's degree, CFA Charter, ten or more years of financial services experience, and expert-level understanding of investments and portfolio management strategies.

Emergency Medicine Physician in Birmingham, AL

Company: TeamHealth

Location: 810 Saint Vincents DrBirmingham, Alabama 35205

Posted Nov 18, 2024

St. Vincent's Birmingham Main in Birmingham, Alabama, is seeking a full-time emergency medicine (EM) physician. The hospital, with 410 beds and a 29-bed emergency department, handles a robust annual volume of 52,000 patients. The role offers competitive compensation, professional liability insurance, and access to free in-house CME resources. The hospital is known for its supportive team environment, cutting-edge facility, and work-life balance.

Executive Director with The Woman's Exchange

Company: Collaborative Strategies

Location: St. Louis, MO

Posted Nov 18, 2024

The Womans Exchange is seeking a dynamic and visionary Executive Director to lead the organization in preserving its longstanding traditions and values, promoting local and international artisans, and supporting womens economic independence. The Executive Director will oversee day-to-day operations, financial management, and strategic planning to ensure the continued success and growth of the organizations mission.

A Locum Tenens Anesthesiologist Is Needed in Missouri WBY# JOB-2997764

Company: Weatherby Healthcare

Location: Springfield, Missouri

Posted Nov 18, 2024

Weatherby Healthcare is offering an Anesthesiology locum tenens position in Springfield, Missouri. The role involves working with a variety of patient types, including general, GI, OB, neuro, regional, vascular, and pediatric cases. The assignment includes 10-15 patients per day, with weekday, days shifts and no call. The company provides competitive compensation, paid malpractice insurance, pre-paid travel and housing expenses, and 24-hour access to a consultant. Weatherby Healthcare, founded in 1995, is a leading expert in locum tenens staffing for healthcare professionals.

Data Literacy & Community Lead

Company: Lee Company

Location: Missouri City, TX

Posted Nov 18, 2024

The Friedkin Group is seeking a Data Literacy & Community Lead to design and implement data-centric programs. The role involves creating a data literacy strategy, developing a data literacy program, and facilitating communities of practice. The ideal candidate should have a background in business analytics, data strategy, and learning & development. They must possess strong communication skills and the ability to manage stakeholders.

Electrophysiologist Is Needed for Locums Coverage in MO CPH# JOB-2998755

Company: CompHealth

Location: St. Louis, Missouri

Posted Nov 18, 2024

CompHealth offers comprehensive support to healthcare providers, including free services for credentialing, travel, housing, and more. They negotiate better pay, arrange housing and travel, and provide malpractice coverage. Their specialized recruiters handle every detail, ensuring a seamless experience. The text highlights their capabilities, scale, and commitment to connecting providers with suitable job opportunities, as demonstrated by their 40-year history in the industry.

Case Management Coordinator (Central Time Zone)

Company: CVS Health

Location: Saint Paul, MN

Posted Nov 18, 2024

CVS Health is seeking a Case Management Coordinator to elevate patient care for dual eligible populations. The role involves collaborating with members, providers, and community organizations to address health and social needs. The coordinator will evaluate members' needs, identify high-risk factors, and coordinate care plan activities. They will also enhance medical appropriateness and quality of care, and monitor, evaluate, and document care. Preferred qualifications include case management, behavioral health, or managed care experience, and a bachelor's degree in behavioral health or human services. The pay range is $21.10 - $44.99, with additional benefits including medical, dental, vision, 401(k), life insurance, disability benefits, well-being programs, and PTO.

Frequently Asked Questions

What types of tech jobs are available in Saint Louis?
Saint Louis hosts a wide spectrum of tech roles, from software engineers (full‑stack, mobile, backend) and data scientists at Centene to cybersecurity analysts at HCA Healthcare. Product managers, UX designers, and DevOps specialists are in demand at logistics firms like UPS and FedEx, while AI/ML engineers find opportunities at startups such as Raptor Labs and Kingfisher Labs.
Are tech roles in Saint Louis remote, hybrid, or on‑site?
Most senior positions at large employers like HCA and Centene offer hybrid options, allowing employees to work from the downtown office two days a week and remotely the rest. Startups in Midtown and The Block typically require on‑site presence to foster collaboration, but many are expanding their remote talent pool due to the pandemic‑shifted culture.
Who are the major tech employers in Saint Louis?
Key employers include HCA Healthcare’s digital health division, Centene’s analytics teams, UPS and FedEx’s logistics tech hubs, Boeing’s aerospace software labs, and local innovators such as Raptor Labs, Kingfisher Labs, and Innovate St. Louis. The city also attracts national firms like Google and Microsoft through satellite offices.
What salary can I expect for tech roles in Saint Louis?
Software engineers earn between $80,000 and $110,000, with senior positions reaching $120,000+. Data scientists typically earn $90,000–$130,000, while cybersecurity experts command $95,000–$140,000. Benefits packages often include health insurance, retirement plans, and relocation stipends, which can significantly increase total compensation.
How can I relocate to Saint Louis for a tech job?
Start by researching neighborhoods: Tower Grove offers a vibrant student vibe, Delmar Loop offers boutique shopping, and Forest Park provides suburban tranquility. Many employers provide relocation assistance, including housing stipends and moving allowances. Utilize the city’s public transit (MetroLink) and bike lanes to stay connected once you arrive.

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