Tech Jobs in SAINT LOUIS, Missouri

49,974 open positions · Updated daily

Saint Louis has become a magnet for tech talent thanks to its blend of cutting‑edge research, a diverse industrial base, and a network of top universities. Companies from AI leaders like C3.ai to health‑tech innovators such as Slyce and biotech giants like Gilead Sciences are expanding their footprints, creating a steady stream of roles that blend software engineering, data science, and product management.

The city’s tech ecosystem spans several key sectors. In addition to AI and health tech, the region hosts a thriving fintech community with firms such as The Money Store and a growing number of manufacturing‑automation startups. Logistics giants like FedEx and Lumen Technologies maintain large engineering teams, while the University of Missouri‑St. Louis and Washington University drive research collaborations that feed the local talent pool.

With a cost of living about 15 % below the national average, Saint Louis offers a high quality of life without the price tag of coastal hubs. Median home prices hover around $200,000, and the average rent for a one‑bedroom apartment is roughly $1,200. Salary transparency is therefore crucial; it lets candidates compare offers against local living costs and negotiate wages that reflect the true value of their work in a city where money stretches further.

RN - Psych Full Time Nights

Company: Mercy

Location: Springfield, Missouri

Posted Nov 01, 2024

Mercy offers a range of incentives for both new and experienced nurses, including sign-on bonuses, relocation assistance, education assistance, and retirement funds. The patient population consists of individuals with various mental health conditions requiring 24-hour intervention, and Mercy provides comprehensive care including psychiatric assessment, therapy, and community resource connections. The job requires a current RN license, Basic Life Support certification, and the ability to handle physical demands such as lifting and prolonged standing.

RN - Nurse - Progressive Care Unit, FT, Nights

Company: Mercy

Location: Festus, Missouri

Posted Oct 31, 2024

Mercy Hospital Jefferson offers numerous incentives for experienced and new RNs, including sign-on bonuses, relocation assistance, loan forgiveness, and tuition reimbursement. They provide a range of benefits such as shift differential pay, annual merit increases, health/dental/vision insurance, paid parental leave, a 401k with employer match, and competitive salaries. The Cardiac Med Intermediate Unit, also known as the Progressive Care Unit, is a fast-paced environment that combines aspects of the ED and ICU, serving mainly cardiac patients with acute respiratory needs.

MCT Laboratory Technologist Trainee

Company: Labcorp

Location: Saint Paul, MN

Posted Oct 31, 2024

Labcorp is seeking a Technologist Trainee for their MCT Department. The role involves on-the-job training in pre-analytical through post-analytical setup and testing of patient samples. The laboratory focuses on screening blood, serum, urine, and meconium samples for drugs of abuse, performing Therapeutic Drug Monitoring (TDM), and STAT testing. The position offers a dynamic work environment, competitive benefits, and opportunities for growth. The ideal candidate should have a Bachelor's degree in chemical, biological, or clinical laboratory science or medical technology, and possess strong research and problem-solving skills.

Patient Care Technician

Company: DaVita

Location: Saint Cloud, FL

Posted Oct 31, 2024

DaVita, an Italian term for 'giving life', is recruiting a Patient Care Technician (PCT) for an outpatient dialysis center. The role involves direct patient care, monitoring patients before, during, and after dialysis treatment, and building long-term relationships with patients suffering from end-stage renal disease. The company offers comprehensive benefits, paid training, and opportunities for career advancement through programs like Clinical Ladders and Bridge to your Dreams. No dialysis experience is required, and healthcare experience is a plus. DaVita is committed to diversity and equal opportunity, striving to be a community first and a company second.

Full-Time Store Merchandising Supervisor

Company: Kohl's

Location: Saint Joseph, MO

Posted Oct 31, 2024

The Merchandising Supervisor role involves leading associates in delivering excellent customer service through sales floor merchandising, pricing, and recovery. Key responsibilities include executing store merchandising standards, maintaining a well-recovered selling floor, coaching and training merchandising associates, and supporting the Operations team. The role also involves leading with integrity, fostering teamwork, and demonstrating a customer service mindset. Required skills include strong verbal/written communication, interpersonal skills, and flexible availability. Preferred qualifications include 2 years of retail experience and supervisory experience.

RN - Nurse - Progressive Care Unit, PT (2-12s), Nights

Company: Mercy

Location: Festus, Missouri

Posted Oct 31, 2024

Mercy Hospital Jefferson offers numerous incentives for nurses, including sign-on bonuses, bridging programs for obtaining higher degrees, loan forgiveness, and various benefits such as shift differential pay, merit increases, tuition reimbursement, health/dental/vision insurance, paid parental leave, 401k with employer match, paid PTO for volunteering, competitive salary, and future career growth. The Cardiac Med Intermediate Unit, also known as the Progressive Care Unit, is a fast-paced environment that combines aspects of the ED and ICU, primarily serving cardiac patients and those with acute respiratory needs.

Director - Surgical Services (Exempt)

Company: Mercy

Location: Springfield, Missouri

Posted Oct 31, 2024

This job posting is for a nursing management position requiring a Bachelor's degree, 3-5 years of management experience, and proficiency in data analysis. The role involves quality and resource management, ensuring compliance with standards, and promoting professional nursing practice. Preferred qualifications include a BSN and Master's degree, and certification in a specialty area. Mercy offers comprehensive benefits, including health, vision, and dental coverage, PTO, tuition reimbursement, and retirement funds. The company values compassion, professionalism, and a positive outlook, emphasizing collaboration and a commitment to excellent care.

RN - ED (PRN)

Company: Mercy

Location: Cassville, Missouri

Posted Oct 31, 2024

Mercy is a healthcare organization that values compassionate care and exceptional service. They offer rewarding careers that align with individual skills and heart. The RN position involves utilizing the nursing process, maintaining professional accountability, and coordinating patient care. Mercy provides great benefits including health, vision, dental coverage, PTO, tuition reimbursement, and retirement funds. They foster a supportive community and encourage innovation in healthcare. The ideal candidate is compassionate, professional, positive, and collaborative.

Senior Commercial Banking Portfolio Manager

Company: Wells Fargo

Location: St. Louis Park, MN

Posted Oct 31, 2024

Wells Fargo is seeking a Senior Commercial Banking Portfolio Manager for their Credit Execution Market Coverage team. The role involves financial research, underwriting, and structuring of complex private banking relationships. The candidate will review business financial statements, resolve moderately complex issues, and lead the Commercial Banking Portfolio Management team. Required qualifications include 4+ years of Commercial Banking Portfolio Management experience, loan negotiation experience, underwriting experience, and strong analytical skills. The job offers a hybrid work schedule and a competitive pay range of $96,600.00 - $188,900.00. Benefits include health benefits, 401(k) Plan, paid time off, and more.

Medical Claims Adjustor (Fully Remote)

Company: CVS Health

Location: Saint Paul, MN

Posted Oct 31, 2024

CVS Health is seeking a candidate with 2+ years of medical claim processing experience for a role involving reviewing and adjusting SF, FI, Reinsurance, and RX claims. The position requires adjudicating complex claims, processing provider refunds, handling customer service inquiries, and ensuring compliance with company practices. The ideal candidate should have DG system claims processing experience, strong communication and interpersonal skills, and an associate degree or equivalent. The role offers a competitive pay range, comprehensive benefits, and opportunities for career growth.

Cook II

Company: Sodexo

Location: St. Louis, MO

Posted Oct 31, 2024

Sodexo offers a comprehensive employee benefits package, including flexible work hours, ongoing training, and a full array of benefits such as medical, dental, vision, and tuition reimbursement. The role of a Cook II involves preparing and creating nutritious dishes, providing high-quality food service, and acting as a team player. Sodexo values its employees, encouraging them to thrive and act with purpose.

Supervisor, Upstream Processing

Company: Thermo Fisher Scientific

Location: St. Louis, MO

Posted Nov 01, 2024

The job posting is for a day shift position in St. Louis, MO, at the Drug Substance Division (Biologics) of Thermo Fisher Scientific. The role involves manufacturing Commercial and Clinical Biologics, adhering to Current Good Manufacturing Practices (cGMPs), and performing various functions related to Upstream (cell culture). Key responsibilities include executing manufacturing batch records, maintaining suite, supplies, equipment, and data, and ensuring a safe and clean work environment. The ideal candidate should have a HS Diploma/GED, a Bachelor's degree preferred, and 5-9 years of relevant work experience. Preferred skills include knowledge of cGMP practices, aseptic techniques, or chemical concepts, strong math skills, critical thinking, problem-solving, and detail orientation. The role requires physical ability to lift 25 lbs independently and stand for 80% of the shift. Benefits include competitive remuneration, healthcare, and a range of employee benefits.

Frequently Asked Questions

What types of tech jobs are available in Saint Louis?
Saint Louis offers a wide range of tech roles, from Software Engineer and Data Scientist to DevOps Engineer, Product Manager, UI/UX Designer, Cybersecurity Analyst, Mobile Developer, and Cloud Engineer. Companies such as C3.ai, Slyce, Gilead Sciences, FedEx, and Lumen Technologies hire for these positions, as do local fintech startups, manufacturing‑automation firms, and logistics tech teams.
Are tech roles in Saint Louis remote or on-site?
Many tech positions in Saint Louis blend remote and on‑site work. Established firms like Amazon and FedEx offer hybrid schedules, while startups such as Slyce often provide fully remote options. On‑site roles remain common for teams that prioritize collaboration, especially in research labs and manufacturing plants.
Who are the major employers for tech talent in Saint Louis?
Key employers in the region include C3.ai, Slyce, Gilead Sciences, FedEx, Lumen Technologies, Amazon, Google (regional office), the University of Missouri‑St. Louis, Washington University, and St. Louis Children’s Hospital. These organizations drive most of the tech hiring in the city.
What are the salary expectations for tech roles in Saint Louis?
Typical salary ranges in Saint Louis are: Software Engineer $75k–$120k, Senior Software Engineer $100k–$150k, Data Scientist $80k–$130k, Product Manager $90k–$140k, and DevOps Engineer $85k–$130k. The median tech salary hovers around $95k, but exact figures vary by experience, specialization, and company size.
What advice should I follow when relocating to Saint Louis for tech work?
Research local neighborhoods such as Clayton, University City, and Laclede’s Hill for housing and commute options. Leverage salary data on JobTransparency to negotiate competitive offers. Attend local meetups like St. Louis Tech Meetup and C3.ai events to build a network. Consider public transit, bike lanes, and parking when choosing a home. Finally, review relocation packages offered by employers and factor in the city’s lower cost of living to maximize your net income.

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