Tech Jobs in SAINT LOUIS, Missouri

49,974 open positions · Updated daily

Saint Louis has become a magnet for tech talent thanks to its blend of cutting‑edge research, a diverse industrial base, and a network of top universities. Companies from AI leaders like C3.ai to health‑tech innovators such as Slyce and biotech giants like Gilead Sciences are expanding their footprints, creating a steady stream of roles that blend software engineering, data science, and product management.

The city’s tech ecosystem spans several key sectors. In addition to AI and health tech, the region hosts a thriving fintech community with firms such as The Money Store and a growing number of manufacturing‑automation startups. Logistics giants like FedEx and Lumen Technologies maintain large engineering teams, while the University of Missouri‑St. Louis and Washington University drive research collaborations that feed the local talent pool.

With a cost of living about 15 % below the national average, Saint Louis offers a high quality of life without the price tag of coastal hubs. Median home prices hover around $200,000, and the average rent for a one‑bedroom apartment is roughly $1,200. Salary transparency is therefore crucial; it lets candidates compare offers against local living costs and negotiate wages that reflect the true value of their work in a city where money stretches further.

Lead Scientist - Environmental Science

Company: Labcorp

Location: Saint Neots, United Kingdom

Posted Oct 18, 2024

Labcorp is seeking a Lead Scientist for Biodegradation services at their Alconbury site near Huntingdon, Cambridgeshire. The role involves providing scientific leadership, ensuring high standards in Biodegradation studies, and maintaining up-to-date knowledge of industry developments. The individual will be the primary interface between Biodegradation Services, Regulatory, Sales, and Marketing. Key responsibilities include leading scientific developments, maintaining effective relationships with clients, and representing Labcorp at conferences and events. Labcorp offers a competitive salary, comprehensive benefits, flexible working, and career development opportunities.

LPN - Inpatient Med/Surg- Nights

Company: Mercy

Location: Sappington, Missouri

Posted Oct 18, 2024

Mercy is encouraging new graduates and experienced LPNs to apply, offering exciting incentives such as sign-on bonuses, education assistance, and loan forgiveness programs. The proposed schedule includes 12-hour shifts for both days and nights, with multiple part-time and full-time options. Mercy emphasizes compassionate care, innovative procedures, and a supportive community. The role is safety-sensitive, requiring constant alertness and safe practices.

RN - Emergency Department, Regional Float Pool

Company: Mercy

Location: Creve Coeur, Missouri

Posted Oct 18, 2024

Mercy Regional Medical Center is offering a range of incentives for experienced nurses, including a sign-on bonus of up to $20,000, relocation assistance, education assistance, and tuition reimbursement. They also provide comprehensive insurance, retirement funds, and shift differentials. The Float Pool offers opportunities for clinical skill development and teamwork across various locations. A Regional Travel RN position is available for experienced ER RNs, offering base rate plus float incentive and shift differential pay.

Occupational Therapy Assistant - COTA - Per Diem

Company: Mercy

Location: Troy, Missouri

Posted Oct 18, 2024

Mercy is a healthcare organization that values compassionate care and exceptional service. They offer careers that align with individual skills and hearts, and have been recognized as a top workplace. The Occupational Therapy Assistant position involves assisting with patient assessments and treatment programs under licensed supervision. Mercy provides great benefits including health coverage, PTO, tuition reimbursement, and retirement funds. They encourage applicants who are compassionate, professional, positive, and advocates for excellent care.

Shift Supervisor Trainee

Company: CVS Health

Location: Saint Paul, MN

Posted Oct 18, 2024

CVS Health is offering a Shift Supervisor Trainee position, an entry-level role that prepares employees for higher-level supervisory roles. The role involves working effectively with store management and crews, supervising the store's crew, and assisting customers with their questions, problems, and complaints. The position requires deductive reasoning, analytical skills, computer skills, and advanced communication skills. Upon successful completion of the training program, trainees are eligible for promotion to Operations Supervisor or Shift Supervisor positions. The company offers a competitive pay range, comprehensive benefits, and a positive work environment.

RN - Nurse - Acute Rehab Unit, FT, Nights

Company: Mercy

Location: Festus, Missouri

Posted Oct 18, 2024

Mercy Hospital Jefferson offers a range of incentives for nurses, including sign-on bonuses, relocation assistance, and loan forgiveness programs. They provide comprehensive care in their rehabilitation unit for patients with neurological conditions. The hospital, a 251-bed acute care facility in Festus, MO, is committed to compassionate care and exceptional service.

Pharmacy Technician

Company: CVS Health

Location: Saint Paul, MN

Posted Oct 18, 2024

CVS Health is inviting applications for Pharmacy Technicians, emphasizing their commitment to human-centric healthcare. The role involves delivering compassionate care, managing prescriptions, and ensuring regulatory compliance. New hires must complete a training program and satisfy state licensing requirements. The position offers opportunities for career growth and a range of benefits, including medical, dental, vision, 401(k), life insurance, disability benefits, well-being programs, and more. CVS Health values accountability, caring, collaboration, innovation, and integrity.

Pharmacy Intern

Company: CVS Health

Location: St. Louis Park, MN

Posted Oct 18, 2024

CVS Health is offering a 3rd year pharmacy intern position with opportunities for professional growth and a chance to make a significant impact in healthcare. The role involves working closely with a licensed pharmacist, ensuring patient safety, and delivering exceptional care. The intern will be responsible for managing patient care programs, leading with empathy, and collaborating with the team to improve healthcare. The ideal candidate should possess strong communication skills, be enrolled in an ACPE accredited college of pharmacy, and have relevant work experience. Proficiency in Microsoft Office Suite is preferred.

Director of Employee Communications

Company: nVent

Location: St. Louis Park, MN

Posted Oct 18, 2024

nVent is seeking a Director of Employee Communications to join their HR Leadership Team. The role involves developing and implementing a global employee communication strategy, leading a team, and collaborating with external communications. The ideal candidate will have a bachelor's degree in a related field, 10+ years of experience, and a proven track record in organizational communication strategies. nVent, a $3.3B company with over 11,000 employees, offers a dynamic global reach, commitment to strengthening communities, and core values centered around innovation, integrity, customer focus, respect, optimism, and accountability.

Clinical Supervisor- Emergency Department (Full Time Nights)

Company: Mercy

Location: Springfield, Missouri

Posted Oct 18, 2024

Join a renowned Emergency Trauma Center with Level 1 Trauma and Stroke recognition, serving as the region's only Regional Burn Center. Offering Sign On Bonuses, PTO, Relocation Assistance, and Student Loan Forgiveness. The dynamic department, with 70 exam/treatment areas and a dedicated Pediatric Emergency Department, fosters positive relationships with Board Certified Emergency Medicine Physicians. The Emergency Trauma Center Nursing Fellowship enhances skills in a fast-paced environment. Mercy, founded by the Sisters of Mercy in 1891, serves a diverse community with exceptional care for 72,000 annual patients.

Physician - Pulmonary Medicine only - St. Mary's Hospital - Richmond Heights MO - Full Time

Company: SSM Health

Location: Saint Louis, Missouri

Posted Oct 18, 2024

St. Mary's Hospital in Richmond Heights, MO is seeking a Pulmonary Medicine Physician. The position offers a competitive 2-year income guarantee and a productivity-based compensation plan. Benefits include malpractice coverage, retirement programs, and CME allowance. Missouri offers a variety of neighborhoods, an affordable housing market, and a booming economy. Cities like Jefferson City and Columbia provide vibrant communities.

RN - ER (Nights)

Company: Mercy

Location: Cassville, Missouri

Posted Oct 18, 2024

Mercy is offering a Sign On Bonus, PTO Frontload, and Relocation Assistance. They are a Top 100 Places to Work according to Modern Healthcare Magazine. The RN position involves utilizing the nursing process to provide patient care, maintaining professional accountability, and coordinating patient care with other departments. Qualifications include a nursing degree, current RN license, and various certifications. The role requires physical abilities to lift, stand, and perform duties. Mercy offers great benefits including health, vision, dental coverage, PTO, tuition reimbursement, and retirement funds. They value compassion, professionalism, and a positive outlook in their employees.

Frequently Asked Questions

What types of tech jobs are available in Saint Louis?
Saint Louis offers a wide range of tech roles, from Software Engineer and Data Scientist to DevOps Engineer, Product Manager, UI/UX Designer, Cybersecurity Analyst, Mobile Developer, and Cloud Engineer. Companies such as C3.ai, Slyce, Gilead Sciences, FedEx, and Lumen Technologies hire for these positions, as do local fintech startups, manufacturing‑automation firms, and logistics tech teams.
Are tech roles in Saint Louis remote or on-site?
Many tech positions in Saint Louis blend remote and on‑site work. Established firms like Amazon and FedEx offer hybrid schedules, while startups such as Slyce often provide fully remote options. On‑site roles remain common for teams that prioritize collaboration, especially in research labs and manufacturing plants.
Who are the major employers for tech talent in Saint Louis?
Key employers in the region include C3.ai, Slyce, Gilead Sciences, FedEx, Lumen Technologies, Amazon, Google (regional office), the University of Missouri‑St. Louis, Washington University, and St. Louis Children’s Hospital. These organizations drive most of the tech hiring in the city.
What are the salary expectations for tech roles in Saint Louis?
Typical salary ranges in Saint Louis are: Software Engineer $75k–$120k, Senior Software Engineer $100k–$150k, Data Scientist $80k–$130k, Product Manager $90k–$140k, and DevOps Engineer $85k–$130k. The median tech salary hovers around $95k, but exact figures vary by experience, specialization, and company size.
What advice should I follow when relocating to Saint Louis for tech work?
Research local neighborhoods such as Clayton, University City, and Laclede’s Hill for housing and commute options. Leverage salary data on JobTransparency to negotiate competitive offers. Attend local meetups like St. Louis Tech Meetup and C3.ai events to build a network. Consider public transit, bike lanes, and parking when choosing a home. Finally, review relocation packages offered by employers and factor in the city’s lower cost of living to maximize your net income.

Related Pages