Tech Jobs in SAINT LOUIS, Missouri

49,974 open positions · Updated daily

Saint Louis has become a magnet for tech talent thanks to its blend of cutting‑edge research, a diverse industrial base, and a network of top universities. Companies from AI leaders like C3.ai to health‑tech innovators such as Slyce and biotech giants like Gilead Sciences are expanding their footprints, creating a steady stream of roles that blend software engineering, data science, and product management.

The city’s tech ecosystem spans several key sectors. In addition to AI and health tech, the region hosts a thriving fintech community with firms such as The Money Store and a growing number of manufacturing‑automation startups. Logistics giants like FedEx and Lumen Technologies maintain large engineering teams, while the University of Missouri‑St. Louis and Washington University drive research collaborations that feed the local talent pool.

With a cost of living about 15 % below the national average, Saint Louis offers a high quality of life without the price tag of coastal hubs. Median home prices hover around $200,000, and the average rent for a one‑bedroom apartment is roughly $1,200. Salary transparency is therefore crucial; it lets candidates compare offers against local living costs and negotiate wages that reflect the true value of their work in a city where money stretches further.

Registered Nurse

Company: Wexford Health Sources

Location: East St. Louis, Illinois

Posted Oct 18, 2024

The job posting is for a Registered Nurse position at Southwestern Illinois Correctional Center in East Saint Louis, IL. The position is full-time, 11p-7a. The nurse will deliver patient care under supervision, direct teaching activities, and guide ancillary personnel. Wexford Health offers competitive benefits including annual increase, up to 40 total paid days off, 401(k) plan with 50% match, and medical, dental, and vision insurance. The requirements include current RN license in Illinois, CPR certification, graduation from an accredited nursing school, and preferred one year of clinical experience.

Catering Services Worker-Missouri Western State University

Company: Aramark

Location: Saint Joseph, MO

Posted Oct 18, 2024

The Catering Services Worker at Aramark is responsible for supporting event operations, including setting up catering and event service, transporting equipment and supplies, serving guests, and cleaning up after events. Previous customer service and catering experience is preferred. The role involves working independently, maintaining cleanliness, and providing excellent customer service. Aramark values equal employment opportunities and career development.

Occupational Therapist - Weekend Option

Company: Mercy

Location: St. Louis, Missouri

Posted Oct 18, 2024

Mercy is a healthcare organization that values compassionate care and exceptional service. They offer careers that align with individual skills and heart, and have been recognized as a top workplace. The position in question is a weekend-only, benefit-eligible role with a premium rate. The role involves providing patient care and participating in special projects. Mercy offers great benefits, including health, vision, and dental coverage, PTO, tuition reimbursement, and retirement funds. They are committed to innovation and pioneering new models of care.

Pharmacist (Full or Part Time)

Company: Walgreens

Location: Saint Michael, MN

Posted Oct 18, 2024

The job involves providing pharmacy consulting services with empathy to patients, offering preventive and clinical healthcare services, and ensuring proper compounding, dispensation, review, and verification of prescribed medications. The role also includes supporting efficient pharmacy workflow, optimizing financials and inventory management, and enhancing patient experience. Key responsibilities include engaging patients, resolving issues, modeling customer service best practices, and participating in community outreach activities. The pharmacist is expected to counsel patients, perform pharmacist tasks, maintain regulatory compliance, and ensure accurate processing of insurance claims. They also assist in staff hiring, training, and performance management, and maintain current knowledge and skills in pharmacy and healthcare.

Manufacturing Planning Coordinator I- Nights

Company: Thermo Fisher Scientific

Location: St. Louis, MO

Posted Oct 18, 2024

The job posting is for a Manufacturing Coordinator position in St. Louis, MO, specifically for the Drug Substance Division. The role involves working in a cleanroom environment adhering to Good Manufacturing Practices (GMP) and safety standards. The work hours are 6:00AM - 6:30PM on a 12-hour rotating schedule, with every other weekend work. The pay is competitive, ranging from $19-21/hour plus a 15% night shift differential. The role involves supporting the manufacture of Commercial and Clinical Biologics, ensuring all consumables are accounted for, and assisting with raw materials and consumables placement. The candidate will also collaborate with production support groups, perform inventory counts, and assist in manufacturing process functions. The ideal candidate should have a high school diploma or GED, preferably with an associates degree in a relevant scientific field. Experience in a related field, preferably in regulatory cleaning/manufacturing, is required. Knowledge of GMP/GLP regulations and proficiency in PCs and Windows applications are essential. The company's mission is to make the world healthier, cleaner, and safer.

Rheumatology Physician St. Charles Wentzville Full Time

Company: SSM Health

Location: Wentzville, Missouri

Posted Oct 18, 2024

The individual is responsible for managing call coverage for medical staff during holidays, vacations, and other time off. They ensure the standard of practice for the patient population and maintain a private office with all clinical decision-making authority. They act as an advisor in establishing operational policies, including purchasing, capital allocations, managed care plan participation, budget, practice expenses, Medicare/Medicaid participation, billing and collection of professional fees, personnel management, risk management, quality assurance, and coding compliance. They also provide after-hours call coverage for patients, participate in community service activities, and ensure all risk management, coding compliance, and quality assurance activities are carried out in the practice. They work in a constant state of alertness and safety.

Pharmacy Technician / Pharm Tech Apprenticeship

Company: Walgreens

Location: St. Louis, MO

Posted Oct 18, 2024

Walgreens is transforming its pharmacy technician roles to a more patient-centric environment. As a Walgreens Pharmacy Technician or Apprentice, you'll interact with customers, develop strong patient relationships, and have access to the latest technology to grow your career. Walgreens offers an 'earn while you learn' Pharmacy Technician Training Program, recognized by ASHP and the Department of Labor, which guides you towards becoming a PTCB Certified Pharmacy Technician. The role involves assisting pharmacists, using pharmacy systems, maintaining customer service, and adhering to state and federal regulations. Walgreens provides training, and prior retail or pharmacy experience is preferred. PTCB certification is also preferred but not required.

Pediatric Gastroenterologist SLUCare Physician Group

Company: SSM Health

Location: Saint Louis, Missouri

Posted Oct 18, 2024

Saint Louis University, a Jesuit institution, is renowned for student learning, research, healthcare, and service. Cardinal Glennon Children's Hospital, a 195-bed facility, offers comprehensive pediatric care with a staff of over 130 full-time faculty from SLU School of Medicine. SLUCare Physician Group, an academic medical practice, provides extensive pediatric healthcare services across the St. Louis region. The St. Louis metropolitan area is praised for its affordable living, quality education, cultural diversity, and abundant recreational sites.

Nurse Practitioner needed: Gastroenterology in Poplar Bluff, MO

Company: Community Health Systems

Location: Moberly, Missouri

Posted Oct 18, 2024

Poplar Bluff Regional Medical Center is seeking a Nurse Practitioner for Gastroenterology. The position offers a competitive salary, commencement bonus, and additional benefits such as marketing, relocation, and CME. The job involves inpatient and outpatient duties, a Monday-Friday schedule, and no call. The hospital is a state-of-the-art facility with 412 beds, located in a clean, safe, family-friendly area in southern Missouri. The community offers access to rivers for outdoor activities, a golf course, a strong public school system, and a lower cost of living compared to the US average.

Pharmacy Tech Buyer I

Company: Mercy

Location: Creve Coeur, Missouri

Posted Oct 18, 2024

Mercy is a healthcare organization that values compassionate care and exceptional service. They offer careers that align with individual skills and heart, having been recognized as a 'Top 100 Places to Work' by Modern Healthcare Magazine. The Pharmacy Tech Buyer position involves managing wholesale drug distribution procurement, assisting in inventory management, and maintaining records. Qualifications include a High School Diploma, active registration with the State Board of Pharmacy, 1 year of pharmacy experience, and Certified Pharmacy Technician (CPhT) certification. Mercy provides comprehensive benefits, including health, vision, and dental coverage, PTO, tuition reimbursement, and retirement funds. They encourage applicants who are compassionate, professional, positive, and collaborative.

Customer Service Associate

Company: Walgreens

Location: Saint Michael, MN

Posted Oct 18, 2024

The text describes a job role focused on delivering a distinctive and delightful customer experience. The responsibilities include engaging customers, resolving issues, and providing efficient checkout service. The role also involves maintaining store cleanliness, implementing asset protection procedures, and ensuring compliance with regulated product laws. The job requires fluency in English, flexibility in scheduling, and preferably six months of retail experience. The position offers a salary range of $15 - $17.5 per hour.

Ultrasound Technologist-FT Bolivar

Company: Mercy

Location: Bolivar, Missouri

Posted Oct 18, 2024

Mercy is a top workplace offering career opportunities that align with individual skills and heart. They provide incentives like a Loan Repayment Assistance Program up to $20,000. The role involves interpreting orders, producing diagnostic ultrasound images, and assisting physicians in interventional procedures. Qualifications include a sonography graduate or registered technologist, 1+ years of relevant experience, and specific certifications. Mercy offers great benefits including health, vision, dental coverage, PTO, tuition reimbursement, and retirement funds.

Frequently Asked Questions

What types of tech jobs are available in Saint Louis?
Saint Louis offers a wide range of tech roles, from Software Engineer and Data Scientist to DevOps Engineer, Product Manager, UI/UX Designer, Cybersecurity Analyst, Mobile Developer, and Cloud Engineer. Companies such as C3.ai, Slyce, Gilead Sciences, FedEx, and Lumen Technologies hire for these positions, as do local fintech startups, manufacturing‑automation firms, and logistics tech teams.
Are tech roles in Saint Louis remote or on-site?
Many tech positions in Saint Louis blend remote and on‑site work. Established firms like Amazon and FedEx offer hybrid schedules, while startups such as Slyce often provide fully remote options. On‑site roles remain common for teams that prioritize collaboration, especially in research labs and manufacturing plants.
Who are the major employers for tech talent in Saint Louis?
Key employers in the region include C3.ai, Slyce, Gilead Sciences, FedEx, Lumen Technologies, Amazon, Google (regional office), the University of Missouri‑St. Louis, Washington University, and St. Louis Children’s Hospital. These organizations drive most of the tech hiring in the city.
What are the salary expectations for tech roles in Saint Louis?
Typical salary ranges in Saint Louis are: Software Engineer $75k–$120k, Senior Software Engineer $100k–$150k, Data Scientist $80k–$130k, Product Manager $90k–$140k, and DevOps Engineer $85k–$130k. The median tech salary hovers around $95k, but exact figures vary by experience, specialization, and company size.
What advice should I follow when relocating to Saint Louis for tech work?
Research local neighborhoods such as Clayton, University City, and Laclede’s Hill for housing and commute options. Leverage salary data on JobTransparency to negotiate competitive offers. Attend local meetups like St. Louis Tech Meetup and C3.ai events to build a network. Consider public transit, bike lanes, and parking when choosing a home. Finally, review relocation packages offered by employers and factor in the city’s lower cost of living to maximize your net income.

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