Tech Jobs in SAINT LOUIS, Missouri

49,974 open positions · Updated daily

Saint Louis has become a magnet for tech talent thanks to its blend of cutting‑edge research, a diverse industrial base, and a network of top universities. Companies from AI leaders like C3.ai to health‑tech innovators such as Slyce and biotech giants like Gilead Sciences are expanding their footprints, creating a steady stream of roles that blend software engineering, data science, and product management.

The city’s tech ecosystem spans several key sectors. In addition to AI and health tech, the region hosts a thriving fintech community with firms such as The Money Store and a growing number of manufacturing‑automation startups. Logistics giants like FedEx and Lumen Technologies maintain large engineering teams, while the University of Missouri‑St. Louis and Washington University drive research collaborations that feed the local talent pool.

With a cost of living about 15 % below the national average, Saint Louis offers a high quality of life without the price tag of coastal hubs. Median home prices hover around $200,000, and the average rent for a one‑bedroom apartment is roughly $1,200. Salary transparency is therefore crucial; it lets candidates compare offers against local living costs and negotiate wages that reflect the true value of their work in a city where money stretches further.

Radiologist Is Needed for Locum Tenens Coverage in MO GMS# JOB-2988727

Company: Global Medical Staffing

Location: Joplin, Missouri

Posted Oct 07, 2024

The text describes a job opportunity for a General Radiology specialist in Joplin, Missouri. The job involves working 3 days a week with 15 patients per shift, performing various procedures such as CT guided biopsy, CT angio, barium GI study, needle biopsy, fluoro, and DEXA scan. The company offers competitive compensation, pre-paid travel and housing, paid malpractice insurance, credentialing assistance, DEA registration, and licensing assistance with cost reimbursement. The company has a global reach and a personal service approach, being part of the CHG Healthcare family of companies.

New Graduate Nurse Residency - ICU - Mercy Washington

Company: Mercy

Location: Washington, Missouri

Posted Oct 07, 2024

Mercy Washington's ICU Residency is now accepting applications for new graduates. The residency offers great incentives such as relocation assistance, stay premium program, education assistance, loan forgiveness, and comprehensive insurance. The 19-bed floor, consisting of a 13-bed ICU and 6-bed Transitional Care Unit, is known for its fast-paced, high-energy environment and excellent teamwork. The diverse patient population provides ample educational opportunities. Qualifications include graduation from an accredited nursing program, current RN license, and certifications in ACLS and BLS.

RN - Oncology, Part time Nights

Company: Mercy

Location: Creve Coeur, Missouri

Posted Oct 07, 2024

The job posting is for a part-time position for Registered Nurses (RNs) with a sign-on bonus of up to $20,000 for experienced RNs and $10,000 for new graduates. The schedule involves two 12-hour shifts per week, including weekends and holidays. Incentives include tuition reimbursement up to $2,000 annually, student loan forgiveness up to $20,000, and a $16,000 RN to BSN Bridge Program. The Oncology unit, with 41 beds, offers opportunities for skill development and growth, including chemotherapy administration certification and leadership roles. The unit focuses on providing compassionate care to patients with complex cancer diagnoses and hematological disorders.

A Missouri Facility Is Seeking a Locums Radiologist CPH# JOB-2988810

Company: CompHealth

Location: Joplin, Missouri

Posted Oct 07, 2024

CompHealth offers a wide range of locum tenens assignments, from short-term to long-term, local to distant locations. They provide expert guidance tailored to individual career needs and phases. Benefits include better pay, complimentary housing and travel, comprehensive malpractice coverage, and simplified credentialing. Specialized recruiters handle all details for General Radiology positions in Joplin, Missouri.

Enjoy working FT equaling 1/3 of the Year - Hybrid Clinic and On-Call OB/GYN Position - Competitive Salary

Company: Ob Hospitalist Group

Location: Sedalia, Missouri

Posted Oct 07, 2024

Bothwell Regional Health Center in Sedalia, MO is seeking OB/GYN physicians for a full-time, hybrid clinic and on-call position. The role involves inpatient and outpatient services, with a focus on improving patient safety and satisfaction. Key benefits include a work-life balance, salaried role, block scheduling, travel cost assistance, CME allowance, and comprehensive benefits package.

Inpatient Neurologist - Mosaic Life Care, St. Joseph MO

Company: Mosaic Life Care

Location: Saint Joseph, Missouri

Posted Oct 07, 2024

Mosaic Life Care's Department of Neurology is recruiting a BE/BC Neurologist for their inpatient team. The position offers a 7 days on/7 days off schedule, a 100% inpatient clinical focus, manageable 24-hour call responsibility, and close teamwork with experienced physicians and support staff. The medical center is equipped with cutting-edge technologies and treatment options, and is part of the Mayo Clinic Network. Benefits include a highly competitive base salary, starting bonus, student loan assistance, comprehensive insurance, professional dues and CME reimbursement, a 401(k) plan, relocation assistance, and onsite concierge services.

Career Path Program/Residency- Mercy Washington

Company: Mercy

Location: Washington, Missouri

Posted Oct 07, 2024

Mercy Washington is offering a Career Path Program for both experienced RNs and graduate nurses. The program includes a sign-on bonus of up to $20,000 for RNs and up to $15,000 for GNs, relocation assistance, education assistance, loan forgiveness, and comprehensive benefits. The program aims to help nurses grow their clinical knowledge and skills.

RN - OR / Operating Room - FT

Company: Mercy

Location: Joplin, Missouri

Posted Oct 07, 2024

Mercy is offering a Sign On Bonus and student loan re-payment assistance for RNs. The position includes benefits such as PTO, shift differentials, Mercy Loyalty Pay Program, health/dental/vision, paid parental leave, 401k with employer match, free Mercy Nurse On-Call, free life insurance, short term disability benefits, referral bonus opportunity, and a Clinical Ladder career development plan. The role involves utilizing the nursing process to provide patient care, maintaining professional accountability, evaluating care effectiveness, coordinating patient care, and maintaining patient rights and confidentiality.

Reg Respiratory Therapist

Company: Mercy

Location: Sappington, Missouri

Posted Oct 07, 2024

Mercy is a healthcare organization that values compassionate care and exceptional service. They offer careers that align with individual skills and talents, and provide benefits such as day-one comprehensive health coverage, PTO, tuition reimbursement, and retirement funds. They are currently offering a sign-on bonus and a loan repayment assistance program for respiratory therapists. The role involves direct patient care, ventilator support, and maintaining life support equipment. Qualifications include a high school diploma, successful completion of a program approved by the National Board for Respiratory Care, licensure in Missouri, minimum 1 year experience, and registration as a therapist by the National Board of Respiratory Care. BLS/CPR certification is also required.

Branch Real Estate Consultant

Company: Edward Jones

Location: St. Louis, MO

Posted Oct 07, 2024

Edward Jones is a Fortune 500 company that values its associates and their contributions. The firm offers a meaningful career with opportunities for collaboration, autonomy, and growth. The Branch Real Estate team focuses on evolving the firm's real estate strategy to meet client expectations and branch team needs. The role requires a Bachelor's degree, organizational skills, exceptional customer service, and understanding of various corporate principles. Edward Jones promotes a long-term career, financial security, and well-being through a rewards program and total compensation approach.

Ultrasound Technologist II - PRN - Springfield

Company: Mercy

Location: Ozark, Missouri

Posted Oct 07, 2024

Mercy is a healthcare organization that values compassionate care and exceptional service. They offer careers that align with individual skills and hearts, and have been recognized as a top place to work. The role involves interpreting orders for exams, producing diagnostic ultrasound images, and assisting physicians in interventional procedures. Qualifications include a degree from a school of sonography or registered technologist, 1+ years of relevant experience, and 2 applicable registries with ARDMS or ARRT. Mercy offers great benefits including health, vision, and dental coverage, PTO, tuition reimbursement, and retirement funds. They are committed to pioneering new models of care and transforming the healthcare experience.

Otolaryngologist - Mosaic Life Care, St. Joseph MO

Company: Mosaic Life Care

Location: Saint Joseph, Missouri

Posted Oct 07, 2024

Mosaic Life Care, a reputable multi-specialty group in St. Joseph, Missouri, is seeking a board-certified Otolaryngologist. The practice, known for its excellence and work-life balance, focuses on general ENT, pediatrics, sinus, nose, thyroid, ear infections, hearing loss, and breathing problems. The successful candidate will join a collegial team of three physicians and one APRN. Mosaic offers a highly competitive salary, bonus, student loan assistance, comprehensive insurance, generous time off, professional development opportunities, and numerous other benefits. Mosaic is a top-rated organization, recognized by the Mayo Clinic Care Network, Truven Health Analytics, CMS, and others.

Frequently Asked Questions

What types of tech jobs are available in Saint Louis?
Saint Louis offers a wide range of tech roles, from Software Engineer and Data Scientist to DevOps Engineer, Product Manager, UI/UX Designer, Cybersecurity Analyst, Mobile Developer, and Cloud Engineer. Companies such as C3.ai, Slyce, Gilead Sciences, FedEx, and Lumen Technologies hire for these positions, as do local fintech startups, manufacturing‑automation firms, and logistics tech teams.
Are tech roles in Saint Louis remote or on-site?
Many tech positions in Saint Louis blend remote and on‑site work. Established firms like Amazon and FedEx offer hybrid schedules, while startups such as Slyce often provide fully remote options. On‑site roles remain common for teams that prioritize collaboration, especially in research labs and manufacturing plants.
Who are the major employers for tech talent in Saint Louis?
Key employers in the region include C3.ai, Slyce, Gilead Sciences, FedEx, Lumen Technologies, Amazon, Google (regional office), the University of Missouri‑St. Louis, Washington University, and St. Louis Children’s Hospital. These organizations drive most of the tech hiring in the city.
What are the salary expectations for tech roles in Saint Louis?
Typical salary ranges in Saint Louis are: Software Engineer $75k–$120k, Senior Software Engineer $100k–$150k, Data Scientist $80k–$130k, Product Manager $90k–$140k, and DevOps Engineer $85k–$130k. The median tech salary hovers around $95k, but exact figures vary by experience, specialization, and company size.
What advice should I follow when relocating to Saint Louis for tech work?
Research local neighborhoods such as Clayton, University City, and Laclede’s Hill for housing and commute options. Leverage salary data on JobTransparency to negotiate competitive offers. Attend local meetups like St. Louis Tech Meetup and C3.ai events to build a network. Consider public transit, bike lanes, and parking when choosing a home. Finally, review relocation packages offered by employers and factor in the city’s lower cost of living to maximize your net income.

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