Tech Jobs in SAINT LOUIS, Missouri

49,974 open positions · Updated daily

Saint Louis has become a magnet for tech talent thanks to its blend of cutting‑edge research, a diverse industrial base, and a network of top universities. Companies from AI leaders like C3.ai to health‑tech innovators such as Slyce and biotech giants like Gilead Sciences are expanding their footprints, creating a steady stream of roles that blend software engineering, data science, and product management.

The city’s tech ecosystem spans several key sectors. In addition to AI and health tech, the region hosts a thriving fintech community with firms such as The Money Store and a growing number of manufacturing‑automation startups. Logistics giants like FedEx and Lumen Technologies maintain large engineering teams, while the University of Missouri‑St. Louis and Washington University drive research collaborations that feed the local talent pool.

With a cost of living about 15 % below the national average, Saint Louis offers a high quality of life without the price tag of coastal hubs. Median home prices hover around $200,000, and the average rent for a one‑bedroom apartment is roughly $1,200. Salary transparency is therefore crucial; it lets candidates compare offers against local living costs and negotiate wages that reflect the true value of their work in a city where money stretches further.

2025 Summer Intern: Accounts Payable

Company: Spectrum

Location: St. Louis, MO

Posted Oct 04, 2024

Spectrum is offering a 10-week, full-time internship program for motivated rising juniors or seniors with a 3.0 GPA or higher, pursuing a degree in Accounting or Finance. The program, designed to provide essential business insights and hands-on experience, includes professional development sessions, networking opportunities, and mentorship. Interns will work on department and team-focused projects, accounting tasks, and professional development activities. The program is named one of the 2023 Top 100 Internship Programs in the United States by WayUp and Yello.

Outpatient Internal Medicine-Upstate Missouri-We have a strategic relationship with University of Missouri

Company: Community Health Systems

Location: Kirksville, Missouri 63501

Posted Oct 04, 2024

Northeast Regional Medical Center in Kirksville, Missouri, is recruiting an Internal Medicine physician. The hospital, a teaching affiliate of Osteopathic Medicine, offers a competitive recruitment package, including a commencement bonus, potential debt assistance, and comprehensive benefits. Kirksville, the location, is known for its historic downtown, Thousand Hills state park, and Truman State University. The hospital provides a wide range of services and is accredited by AOA.

Internal Medicine opening near Chicago, IL

Company: Archway Physician Recruitment

Location: Saint John, Indiana

Posted Oct 04, 2024

Archway Physician Recruitment is currently recruiting for an Internal Medicine position near Chicago, IL, specifically in Saint John, Indiana. The company aims to be the top choice for all physician recruitment needs nationwide.

Nocturnist Physician in St. Louis, Missouri

Company: TeamHealth

Location: 11133 Dunn RdSt. Louis, Missouri 63136

Posted Oct 04, 2024

Christian Hospital in St. Louis, Missouri is seeking a skilled nocturnist to join their established hospital medicine team. The full-time position offers a desirable schedule of 7 days on, 7 days off, working nights. The physician will provide various levels of patient care to a diverse population, with a closed ICU and no procedures. The hospital supports J-1 waiver consideration and offers a generous sign-on incentive. The position provides autonomy, quality patient interactions, and the assistance of a caring medical director.

Nocturnist Physician in St. Peters, MO

Company: TeamHealth

Location: 10 Hospital DrSt. Louis, Missouri 63376

Posted Oct 04, 2024

Barnes-Jewish St. Peters Hospital in St. Peters, Missouri, is seeking a full-time nocturnist for their hospital medicine (HM) team. The role involves performing admissions on all levels of patient acuity and focusing on direct patient care. The position offers a collaborative work environment with experienced advanced practice clinicians and a quality clinical support system. The schedule is 7pm-7am, 7 days on, 7 days off, with no procedures, codes, or ICU management responsibilities. The hospital uses the EPIC EMR system. The hospital is expanding coverage with in-house physician presence from 7pm-7am, offering a work-life balance and career growth opportunities. The hospital has a reputable program, a veteran medical director, and is an industry leader in hospital medicine.

Nocturnist needed at Lake of the Ozarks, MO

Company: Archway Physician Recruitment

Location: Osage Beach, Missouri

Posted Oct 04, 2024

This job posting is for a full-time, permanent Nocturnist position at a multi-specialty group in Osage Beach, Missouri. The position offers a competitive salary, comprehensive benefits, and high earning potential. The Nocturnist will work night shifts, 12-hour blocks, with a minimum of 15 shifts per month. The employer provides a range of benefits including a 401K retirement plan, health/dental/vision insurance, malpractice insurance, and a negotiable sign-on bonus. Relocation assistance is also available. The company, Archway Physician Recruitment, is a national contingency placement firm assisting hospitals and medical groups with their placement needs.

2025 Summer Intern: Financial Reporting

Company: Spectrum

Location: St. Louis, MO

Posted Oct 04, 2024

Spectrum offers a highly-regarded 10-week internship program for motivated juniors and seniors in Accounting or Finance. The program provides professional development, networking opportunities, and mentorship. Interns will work on department-focused projects and professional development sessions. The Financial Reporting Intern will support the Financial Reporting Department with tasks such as facilitating internal control consistency, assisting with SOX walkthroughs, and supporting the preparation of financial statements and SEC filings.

Family Medicine EM Physician

Company: HCA

Location: Belton, Missouri 64012

Posted Oct 04, 2024

Belton Regional Medical Center is seeking an experienced FM/IM trained emergency medicine physician for a Level III Trauma Center in Belton, Missouri. The position offers a sign-on bonus, competitive W2 compensation, robust benefits, and opportunities for professional development. The medical center is a 71-bed acute-care facility with 260+ physicians and 300+ staff, located in the Kansas City region. It has received an 'A' grade from Leapfrog Group and the Healthgrades Patient Safety Excellence Award.

Hospitalist Nocturnist in Birmingham, AL

Company: TeamHealth

Location: 810 Saint Vincents DrBirmingham, Alabama 35205

Posted Oct 04, 2024

St. Vincent Birmingham is expanding its nocturnist coverage at its flagship facility in downtown Birmingham. This position offers competitive compensation, 24/7 intensivist coverage, comprehensive specialty support, APC support for pager calls, moderate volumes, and a sign-on bonus. The facility is a large referral center with 400 beds, offering excellent compensation including RVU and quality bonus. It is a highly sought-after location within the Ascension St. Vincent System.

Facility in Missouri Seeks a Locums Hospitalist CPH# JOB-2984267

Company: CompHealth

Location: Missouri

Posted Oct 04, 2024

CompHealth offers comprehensive services for hospitalists, including credentialing, travel, housing, and malpractice coverage arrangements. They negotiate better pay, deposit it weekly, and provide a user-friendly online portal for assignment details and time entry. With a specialized recruiter handling every detail, CompHealth aims to simplify the process and help providers achieve success with less worry.

RN - ICU / FT, Fulltime / Night Shift

Company: Mercy

Location: Joplin, Missouri

Posted Oct 04, 2024

Mercy is offering a Sign On Bonus and student loan re-payment assistance for RNs. They provide comprehensive benefits including PTO, health/dental/vision, 401k with employer match, and paid parental leave. The role involves utilizing the nursing process to provide patient care, maintaining professional accountability, and coordinating patient care with other departments. Mercy values compassionate care and offers opportunities for career growth and innovation.

Outpatient Internal Medicine Physician - St. Petersburg, Florida - $300,000+ Compensation Potential

Company: Inspire Healthcare

Location: Saint Petersburg, Florida

Posted Oct 04, 2024

This job posting describes an outpatient value-based care opportunity in Internal Medicine, Family Medicine, or Geriatrics in St. Petersburg, Florida. The role offers a great work-life balance with no nights or weekends, a competitive base salary, quarterly bonuses, and comprehensive benefits. The community is praised for its affordable housing, coastal beachside location, and endless outdoor activities. The company, Inspire Healthcare, emphasizes personal relationships, customer service, and a focus on primary care settings.

Frequently Asked Questions

What types of tech jobs are available in Saint Louis?
Saint Louis offers a wide range of tech roles, from Software Engineer and Data Scientist to DevOps Engineer, Product Manager, UI/UX Designer, Cybersecurity Analyst, Mobile Developer, and Cloud Engineer. Companies such as C3.ai, Slyce, Gilead Sciences, FedEx, and Lumen Technologies hire for these positions, as do local fintech startups, manufacturing‑automation firms, and logistics tech teams.
Are tech roles in Saint Louis remote or on-site?
Many tech positions in Saint Louis blend remote and on‑site work. Established firms like Amazon and FedEx offer hybrid schedules, while startups such as Slyce often provide fully remote options. On‑site roles remain common for teams that prioritize collaboration, especially in research labs and manufacturing plants.
Who are the major employers for tech talent in Saint Louis?
Key employers in the region include C3.ai, Slyce, Gilead Sciences, FedEx, Lumen Technologies, Amazon, Google (regional office), the University of Missouri‑St. Louis, Washington University, and St. Louis Children’s Hospital. These organizations drive most of the tech hiring in the city.
What are the salary expectations for tech roles in Saint Louis?
Typical salary ranges in Saint Louis are: Software Engineer $75k–$120k, Senior Software Engineer $100k–$150k, Data Scientist $80k–$130k, Product Manager $90k–$140k, and DevOps Engineer $85k–$130k. The median tech salary hovers around $95k, but exact figures vary by experience, specialization, and company size.
What advice should I follow when relocating to Saint Louis for tech work?
Research local neighborhoods such as Clayton, University City, and Laclede’s Hill for housing and commute options. Leverage salary data on JobTransparency to negotiate competitive offers. Attend local meetups like St. Louis Tech Meetup and C3.ai events to build a network. Consider public transit, bike lanes, and parking when choosing a home. Finally, review relocation packages offered by employers and factor in the city’s lower cost of living to maximize your net income.

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