Tech Jobs in SAINT LOUIS, Missouri

49,974 open positions · Updated daily

Saint Louis has become a magnet for tech talent thanks to its blend of cutting‑edge research, a diverse industrial base, and a network of top universities. Companies from AI leaders like C3.ai to health‑tech innovators such as Slyce and biotech giants like Gilead Sciences are expanding their footprints, creating a steady stream of roles that blend software engineering, data science, and product management.

The city’s tech ecosystem spans several key sectors. In addition to AI and health tech, the region hosts a thriving fintech community with firms such as The Money Store and a growing number of manufacturing‑automation startups. Logistics giants like FedEx and Lumen Technologies maintain large engineering teams, while the University of Missouri‑St. Louis and Washington University drive research collaborations that feed the local talent pool.

With a cost of living about 15 % below the national average, Saint Louis offers a high quality of life without the price tag of coastal hubs. Median home prices hover around $200,000, and the average rent for a one‑bedroom apartment is roughly $1,200. Salary transparency is therefore crucial; it lets candidates compare offers against local living costs and negotiate wages that reflect the true value of their work in a city where money stretches further.

Video & Motions Graphic Designer

Company: Intersection

Location: Minneapolis–Saint Paul, MN

Posted Oct 02, 2024

The job posting is for a Midlevel Video and Motion Graphics Designer ProducerEditor at Intersection, a company that delivers programming and advertising to cities. The role involves leading the creation of high-end multimedia projects, managing multiple projects, and collaborating with marketing managers and external partners.

Business Analyst - Entry Level

Company: CGI

Location: St. Louis, MO

Posted Oct 02, 2024

CGI is seeking a Business Analyst for an entry-level position in St. Louis, MO. The role involves becoming an industry expert, collaborating with thought leaders to solve complex challenges, assessing user requirements, and providing data-driven recommendations. The company offers a competitive salary, comprehensive benefits, and opportunities for career growth and development. CGI values diversity and inclusion, and offers a range of benefits including health insurance, 401(k) with company match, paid leave, and tuition assistance. The position requires a bachelor's degree, a positive attitude, and strong problem-solving skills.

Physician - (S) (FAC) Cardiology SLUCare Physician Group

Company: SSM Health

Location: Saint Louis, Missouri

Posted Oct 02, 2024

SSM Health Saint Louis University Hospital is seeking a board certified Cardiovascular Diseases and Echocardiography specialist for the Medical Director, Echocardiography Lab position. The ideal candidate will develop a busy outpatient and inpatient clinical cardiology practice with a focus on echocardiography and TEE imaging. The role offers significant potential for structural TEE imaging, interaction with cardiology fellows and Echo Lab staff, and conducting investigator-initiated and industry-sponsored trials.

Accounts Payable Clerk

Company: Protective Life

Location: St. Louis, MO

Posted Oct 02, 2024

The company Protective is committed to providing an inclusive culture and protecting its employees' wellbeing. The job posting is for an Accounts Payable Clerk position, which involves processing manual check requests, printing and mailing checks, and maintaining internal controls. The company offers a range of benefits, including health insurance, paid time off, and a 401k plan.

RN - Medical ICU, Part Time

Company: Mercy

Location: Springfield, Missouri

Posted Oct 02, 2024

The MICU is a fast-paced environment offering a wide range of experiences and opportunities for nurses. It is staffed by highly skilled professionals who care for critically ill patients with multi-system management needs. The unit provides a strong foundation for a nursing career, with a diverse patient population and continuous learning opportunities. Nurses are required to have a current RN license, Basic Life Support certification, and meet physical demands including lifting 50 pounds and prolonged standing.

Cardiac Sonographer|PT Days

Company: Mercy

Location: Sappington, Missouri

Posted Oct 02, 2024

Mercy Hospital Ardmore Non-invasive Cardiology is seeking a Sonographer for a career ladder position. The role involves providing exceptional service to patients, demonstrating fairness, integrity, and compassion. Mercy offers great benefits including health, vision, and dental coverage, PTO, tuition reimbursement, and employer-matched retirement funds. The hospital is committed to compassionate care and professionalism, with opportunities for career advancement and innovation in technology.

Healthcare Host/Hostess

Company: Sodexo

Location: St. Louis, MO

Posted Oct 02, 2024

Sodexo offers comprehensive employee benefits packages and detailed job descriptions. The role of a Healthcare Host/Hostess involves delivering meal carts, aiding in meal setup, discarding soiled trays, taking inventory, and performing sanitation tasks. The company values communication skills, teamwork, adaptability, and a passion for maintaining a healthy and safe environment. Sodexo is an equal opportunity employer.

LPN GIG- Flex/Per Diem/PRN - $30/hr base + incentives - Mercy Joplin

Company: Mercy

Location: Joplin, Missouri

Posted Oct 02, 2024

Mercy Joplin Hospital is offering a flexible per diem/flex LPN position with incentives. The base rate is $30/hr with variable shift incentives. No weekend, holiday, or shift requirements. The Gig Nursing Program requires scheduling a minimum number of hours, being available on short notice, and flexibility. Qualifications include a valid Missouri LPN license, one year of recent inpatient LPN experience, and BLS certification. IV certification is required for LPNs working in Missouri. The position is safety-sensitive, requiring constant alertness and safe work practices.

Product Owner II

Company: Federal Reserve System

Location: St. Louis, MO

Posted Oct 02, 2024

The Federal Reserve Bank of St Louis is looking for a Product Owner II for their Invoice Processing Platform. The role involves prioritizing and delivering solutions, partnering with stakeholders, and maintaining a product backlog. The job requires a bachelor's degree, 3+ years of experience, and a service-oriented mindset.

Branch Office Administrator

Company: Edward Jones

Location: Missouri City, TX

Posted Oct 02, 2024

Edward Jones is seeking a Branch Office Administrator (BOA) to join their team. The role involves working closely with Financial Advisors to help clients achieve their long-term financial goals. The BOA will be the first point of contact for clients, responsible for delivering exceptional personalized service, actively listening for additional service needs, and driving marketing activities. The company offers comprehensive training, a wide support network, and a culture of continuous improvement and professional development. Benefits include a competitive compensation package, paid time off, and a rewards program. The ideal candidate should have strong relationship-building skills, the ability to work independently, and proficiency in office technology.

QC Technician - Days

Company: Thermo Fisher Scientific

Location: St. Louis, MO

Posted Oct 02, 2024

Thermo Fisher Scientific is seeking a candidate for a fast-paced role in St. Louis, MO. The job involves working with hazardous/toxic materials, performing inspections and sampling on incoming materials, and maintaining chemical retain inventory. The candidate must have a high school diploma, minimum 1 year of cGMP experience, and confirmed experience in a regulated clean room environment. The role offers a M-F work week, 401K match, medical, dental, and vision insurance, and an annual bonus incentive. The company is a world leader in science and innovation, committed to making the world healthier, cleaner, and safer.

RN - Cardiac Stepdown- Nights

Company: Mercy

Location: Creve Coeur, Missouri

Posted Oct 02, 2024

Mercy is inviting both experienced and new graduate RNs to apply for their Critical Care Residency program. The Cardiac Stepdown unit, comprising MPCU, CPCU, and Tele2, treats patients requiring closer monitoring than a general med-tele floor but not sick enough for ICU. Available shifts are nights (7:00pm-7:30am). Mercy offers competitive benefits including health, vision, dental coverage, PTO, tuition reimbursement, and retirement funds. The role is safety-sensitive, requiring constant alertness. Mercy values compassion, professionalism, and a positive outlook.

Frequently Asked Questions

What types of tech jobs are available in Saint Louis?
Saint Louis offers a wide range of tech roles, from Software Engineer and Data Scientist to DevOps Engineer, Product Manager, UI/UX Designer, Cybersecurity Analyst, Mobile Developer, and Cloud Engineer. Companies such as C3.ai, Slyce, Gilead Sciences, FedEx, and Lumen Technologies hire for these positions, as do local fintech startups, manufacturing‑automation firms, and logistics tech teams.
Are tech roles in Saint Louis remote or on-site?
Many tech positions in Saint Louis blend remote and on‑site work. Established firms like Amazon and FedEx offer hybrid schedules, while startups such as Slyce often provide fully remote options. On‑site roles remain common for teams that prioritize collaboration, especially in research labs and manufacturing plants.
Who are the major employers for tech talent in Saint Louis?
Key employers in the region include C3.ai, Slyce, Gilead Sciences, FedEx, Lumen Technologies, Amazon, Google (regional office), the University of Missouri‑St. Louis, Washington University, and St. Louis Children’s Hospital. These organizations drive most of the tech hiring in the city.
What are the salary expectations for tech roles in Saint Louis?
Typical salary ranges in Saint Louis are: Software Engineer $75k–$120k, Senior Software Engineer $100k–$150k, Data Scientist $80k–$130k, Product Manager $90k–$140k, and DevOps Engineer $85k–$130k. The median tech salary hovers around $95k, but exact figures vary by experience, specialization, and company size.
What advice should I follow when relocating to Saint Louis for tech work?
Research local neighborhoods such as Clayton, University City, and Laclede’s Hill for housing and commute options. Leverage salary data on JobTransparency to negotiate competitive offers. Attend local meetups like St. Louis Tech Meetup and C3.ai events to build a network. Consider public transit, bike lanes, and parking when choosing a home. Finally, review relocation packages offered by employers and factor in the city’s lower cost of living to maximize your net income.

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