Tech Jobs in SAINT LOUIS, Missouri
Saint Louis has become a magnet for tech talent thanks to its blend of cutting‑edge research, a diverse industrial base, and a network of top universities. Companies from AI leaders like C3.ai to health‑tech innovators such as Slyce and biotech giants like Gilead Sciences are expanding their footprints, creating a steady stream of roles that blend software engineering, data science, and product management.
The city’s tech ecosystem spans several key sectors. In addition to AI and health tech, the region hosts a thriving fintech community with firms such as The Money Store and a growing number of manufacturing‑automation startups. Logistics giants like FedEx and Lumen Technologies maintain large engineering teams, while the University of Missouri‑St. Louis and Washington University drive research collaborations that feed the local talent pool.
With a cost of living about 15 % below the national average, Saint Louis offers a high quality of life without the price tag of coastal hubs. Median home prices hover around $200,000, and the average rent for a one‑bedroom apartment is roughly $1,200. Salary transparency is therefore crucial; it lets candidates compare offers against local living costs and negotiate wages that reflect the true value of their work in a city where money stretches further.
Physician - Division Director Pulmonary, Critical Care and Sleep Medicine
Company: SSM Health
Location: Saint Louis, Missouri
Posted Oct 06, 2025
Academic Gastroenterologist - Join Saint Louis University for a Full-Time Faculty Role
Company: SSM Health
Location: Saint Louis, Missouri
Posted Oct 06, 2025
Nurse Practitioner, NeuroCritical Care
Company: SSM Health
Location: Saint Louis, Missouri
Posted Oct 06, 2025
Physician - Anatomic and Clinical Pathologist - Full Time Academic - SLUCare Physician Group
Company: SSM Health
Location: Saint Louis, Missouri
Posted Oct 06, 2025
Hospitalist Physician - Mosaic Life Care, St. Joseph MO
Company: Mosaic Life Care
Location: Saint Joseph, Missouri
Posted Oct 05, 2025
Physician - Biochemical Geneticist - Full Time Academic - SLUCare Physician Group
Company: SSM Health
Location: Saint Louis, Missouri
Posted Oct 06, 2025
Psychiatry - Mosaic Life Care, Maryville MO
Company: Mosaic Life Care
Location: Maryville, Missouri
Posted Oct 04, 2025
Division Chief of Vascular Surgery | SLU Care | St. Louis, Missouri (MO)
Company: Jackson Physician Search
Location: Missouri
Posted Oct 04, 2025
Pediatric ICU Nurse Practitioner (PNP-AC) - Saint Louis, MO
Company: SSM Health
Location: Saint Louis, Missouri
Posted Oct 04, 2025
Headache Neurologist - Saint Lukes Marion Bloch Neuroscience Institute - Kansas City, MO
Company: Saint Luke's Health System
Location: Kansas City, Missouri
Posted Oct 04, 2025
Physician - Plastic Microsurgeon - Academic - SLUCare Physician Group
Company: SSM Health
Location: Saint Louis, Missouri
Posted Oct 05, 2025