Tech Jobs in San Diego, CA

1,131,707 open positions · Updated daily

San Diego's tech scene blends a sunny coastal vibe with a robust research ecosystem. The city hosts world‑class life‑science labs, defense R&D facilities, and a growing startup cluster that thrives on collaboration with nearby universities like UC San Diego and San Diego State. Recent data shows a 12% year‑over‑year increase in tech hires, driven by demand for AI, cybersecurity, and marine technology.

Key industries include biotech and pharmaceuticals—home to Illumina, Pfizer, and Gilead—, defense contractors such as Lockheed Martin and Northrop Grumman, and software & cloud services firms like Qualcomm, Amazon Web Services, and local SaaS startups in Mission Valley. The city’s proximity to the U.S. Naval Base and NASA’s JPL also fuels niche opportunities in aerospace and data analytics.

San Diego’s median rent for a two‑bedroom apartment tops $2,800, and the overall cost‑of‑living index sits 26% above the national average. Because housing and transportation costs are high, knowing the exact salary range before you apply is crucial. Our transparent listings let candidates compare offers, negotiate confidently, and evaluate whether a role meets their financial goals.

Registered Nurse, Pediatric CVICU

Company: CHRISTUS Health (IHE/Hosted)

Location: San Antonio, TX

Posted Aug 21, 2025

Continues to develop the ability to cope with and manage contingencies of clinical nursing. Addresses increasingly complex psychological, emotional, cultural,…

Sr. IT Security Analyst

Company: Omnivision Technologies

Location: Santa Clara, CA

Posted Aug 21, 2025

Experience working with information security teams and functions, such as security engineering, security operations centers, vulnerability assessment,…

Travel RN Infection Control Practitioner

Company: Cambay Healthcare LLC

Location: San Diego, CA

Posted Aug 21, 2025

Active California RN License and BLS certification. BLS and Infection Control certifications required. Investigate outbreaks and recommend preventive measures.

Senior Tax Associate

Company: Distinct Recruitment

Location: San Antonio, TX

Posted Aug 21, 2025

Help with management and strategy as part of a wider team. Or send me a message or connection request on LinkedIn and we’ll pick things up from there.

Part-time Preschool Teacher

Company: Aspen Leaf Preschool

Location: San Diego, CA

Posted Aug 21, 2025

Must have current first aid and CPR certification. Education: Must have at least 12 post-secondary semester units in early childhood education from an…

Class A Driver - Days - San Antonio

Company: Johnson Brothers - Maverick of Texas

Location: San Antonio, TX

Posted Aug 21, 2025

Minimum 3 year driving experience (tractor/trailer) / 5 years preferred. Must possess a valid Class A CDL. Unload the pallet of product at each respective cross…

Teacher - SDC ESN 4th - 6th - Zanker Elementary School - 010556

Company: Milpitas Unified School District

Location: Milpitas, CA

Posted Aug 21, 2025

A valid California driver=s license. Evaluate each student=s social and academic needs and develop and Individual Educational Program (IEP).

Call Center Representative - Onsite Work Only - NO REMOTE WORK

Company: Magellan Solutions USA

Location: Palo Alto, CA

Posted Aug 21, 2025

Answers incoming calls and communicates with clients with respect, courtesy, empathy, tact, and professionalism. Friday and Saturday: 11:00 pm - 7:00 am.

Accountant (On-Site)

Company: Wilshire Law Firm

Location: Los Angeles, CA

Posted Aug 21, 2025

Collaborate with the outside CPA firm on tax filings and state deadline requirements. You will handle accounting functions ranging from reconciliations and…

Staff Accountant

Company: AppleOne

Location: Los Angeles, CA

Posted Aug 21, 2025

For temporary assignments lasting 13 weeks or longer, the Company is pleased to offer major medical, dental, vision, 401k and any statutory sick pay where…

Custodian (Days)

Company: The DoSeum

Location: San Antonio, TX

Posted Aug 21, 2025

*Dependability *- Follows instructions, responds to management direction; Takes responsibility for own actions. High school diploma or G.E.D.

Custodian (Nights) - Full-Time

Company: The DoSeum

Location: San Antonio, TX

Posted Aug 21, 2025

*Dependability *- Follows instructions, responds to management direction; Takes responsibility for own actions. High school diploma or G.E.D.

Frequently Asked Questions

What types of tech jobs are available in San Diego?
San Diego offers a spectrum of tech roles: software engineers (frontend, backend, full‑stack), data scientists, machine learning engineers, cybersecurity analysts, bioinformatics specialists, embedded systems developers, product managers, UX/UI designers, and DevOps engineers. Companies like Qualcomm, Illumina, Pfizer, and local SaaS firms hire across these disciplines.
Is remote work common for tech positions in San Diego?
About 60% of tech roles in San Diego allow remote or hybrid arrangements. Major employers such as Amazon, Google, and Northrop Grumman offer flexible schedules, while many startups maintain on‑site teams to foster collaboration. Remote candidates should verify the company’s policy during the interview process.
Who are the major tech employers in San Diego?
Key employers include Qualcomm, Illumina, Pfizer, Gilead, Lockheed Martin, Northrop Grumman, Amazon Web Services, Google, NASA’s Jet Propulsion Laboratory, the University of California San Diego, and a growing number of SaaS startups in Mission Valley, La Jolla, and Downtown.
What are the salary expectations for tech roles in San Diego?
Median salaries vary by role: software engineers earn between $90k–$140k, data scientists $100k–$150k, bioinformatics professionals $110k–$160k, and cybersecurity analysts $95k–$140k. Benefits and equity packages often supplement base pay, especially in biotech and defense sectors.
How can I prepare for relocating to San Diego for tech work?
Research neighborhoods: Mission Valley and La Jolla offer high‑tech hubs with easy commutes; Downtown offers vibrant nightlife; and Point Loma provides a quieter coastal feel. Compare rental costs, school districts, and commute times. Attend local meetups, such as the San Diego DevOps Meetup or the SD Tech Community, to network. Utilize our salary transparency data to negotiate offers that align with your cost of living.

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