Tech Jobs in San Mateo, CA

1,130,167 open positions · Updated daily

San Mateo sits on the edge of Silicon Valley, offering easy access to BART and a walkable downtown with cafes, parks, and coworking hubs. The city hosts a vibrant mix of startups, Fortune 500 tech firms, and research labs, drawing talent from Stanford, UC Berkeley, and major tech schools nearby.

Tech roles range from cloud infrastructure and AI research to fintech product management and cybersecurity architecture. Companies such as Salesforce, Adobe, Twitter, and Uber maintain regional offices, while emerging startups like Scribe and Sinequa build products in healthtech and search AI. Biotech firms in nearby Redwood City and biotech incubators in San Mateo’s Hillsdale area further diversify the ecosystem.

Living costs are high: median home price exceeds $1.4 million and the average rent for a 1‑bedroom apartment is around $3,200/month. Salary transparency lets candidates compare offers, negotiate effectively, and align compensation with the cost of living and local market rates.

Outpatient Staff Pharmacist

Company: UC San Diego Health

Location: San Diego, CA

Posted Sep 01, 2025

Demonstrate knowledge of pharmacy state and federal regulations; interpersonal and customer service skills; supervisory skills to include workload management;…

Lead Tax Accountant/Tax Corporate Specialist

Company: MarCal Recruiting

Location: San Antonio, TX

Posted Sep 02, 2025

Strong computer and technical skills, with the ability to adapt to new platforms quickly. Gain exposure to high-level, high-net-worth client strategies.

Registry Data Systems Analyst- Remote

Company: UC San Diego Health

Location: San Diego, CA

Posted Sep 01, 2025

Demonstrated ability to communicate technical information to technical and non-technical personnel at various levels in the organization.

CNC Machine Operator

Company: Aerotek

Location: North Hollywood, CA

Posted Sep 01, 2025

Aerotek Skilled-Trades Division is seeking CNC MACHINE OPERATOR to perform CNC machine operation on various manufactured components in the Aerospace…

Digital Manufacturing Project Manager

Company: Takeda Pharmaceutical

Location: Los Angeles, CA

Posted Sep 02, 2025

Communication: Exceptional written and verbal communication skills; ability to simplify technical concepts for non-technical audiences.

Security Professional - Biopharmaceutical Company

Company: Allied Universal®

Location: San Diego, CA

Posted Sep 02, 2025

Current driver’s license if driving a company- or customer-owned vehicle. Graduate of a Certified Public Safety Academy (military or civilian) or verified work…

General Construction Carpenter (Decks, Fences, Drywall, Painting)

Company: Shpak Construction Group LLC

Location: San Antonio, TX

Posted Sep 01, 2025

Must have your own basic tools (drill, circular saw, jigsaw, level, tape measure, hammer, etc.). These rates apply if you have construction experience, know how…

Business Process & Data Analyst - Contract

Company: UC San Diego

Location: San Diego, CA

Posted Sep 01, 2025

Demonstrated ability to communicate technical information to technical and non-technical personnel at various levels in the organization.

Sr. Custodian - TP128773

Company: UC San Diego

Location: San Diego, CA

Posted Sep 01, 2025

Under supervision, performs semi-skilled and skilled cleaning of College Residences /Dining Halls facilities, meeting rooms, study rooms, laundry facilities,…

Sous Chef

Company: Cocola Bakery

Location: San Jose, CA

Posted Sep 01, 2025

Monitor store cleanliness and up-keep. Attention to detail and excellent customer service are a must. Manage employees in an efficient and professional manner.

Customer Service Representative

Company: The Atlas Vision

Location: San Diego, CA

Posted Sep 01, 2025

Perform data entry tasks to maintain accurate records of customer interactions. Handle debit/credit transactions accurately when required.

Sous Chef

Company: UC San Diego

Location: San Diego, CA

Posted Sep 01, 2025

Decision-making, reasoning, ability to develop original ideas to solve problems, operations analysis, and quality control analysis. Days, 8 hrs/day, Variable.

Frequently Asked Questions

What types of tech jobs are available in San Mateo, CA?
San Mateo hosts roles in software engineering (full‑stack, mobile, data), product management, UX/UI design, DevOps, AI/ML research, cybersecurity, cloud architecture, fintech development, healthtech R&D, and biotech software support.
Are tech jobs in San Mateo remote, on‑site, or hybrid?
The majority (≈65%) of openings require on‑site presence in Downtown or Hillsdale, but 30% offer hybrid schedules and 5% are fully remote, reflecting the city’s mix of legacy firms and agile startups.
Who are the major employers in San Mateo?
Key employers include Salesforce, Adobe, Twitter, Uber, Lyft, Palantir, and regional offices of Google, LinkedIn, and Meta. Startups such as Scribe, Sinequa, and local biotech incubator companies also dominate hiring.
What are the salary expectations for tech roles in San Mateo?
Base salaries for software engineers begin at $110,000 and average $150,000–$170,000 for senior roles; product managers average $135,000–$160,000; data scientists average $145,000; cybersecurity roles average $140,000–$165,000. Total compensation often includes bonuses, RSUs, and benefits.
What should I know before relocating to San Mateo for tech work?
Plan for high housing costs—factor in $3,200 monthly rent or $1.4 million median home price. Evaluate commute options: BART, Caltrain, and local bus routes serve downtown. Research local coworking spaces, networking events, and community groups like San Mateo Tech Meetups to ease transition.

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