Tech Jobs in San Mateo, CA

1,130,358 open positions · Updated daily

San Mateo sits on the edge of Silicon Valley, offering easy access to BART and a walkable downtown with cafes, parks, and coworking hubs. The city hosts a vibrant mix of startups, Fortune 500 tech firms, and research labs, drawing talent from Stanford, UC Berkeley, and major tech schools nearby.

Tech roles range from cloud infrastructure and AI research to fintech product management and cybersecurity architecture. Companies such as Salesforce, Adobe, Twitter, and Uber maintain regional offices, while emerging startups like Scribe and Sinequa build products in healthtech and search AI. Biotech firms in nearby Redwood City and biotech incubators in San Mateo’s Hillsdale area further diversify the ecosystem.

Living costs are high: median home price exceeds $1.4 million and the average rent for a 1‑bedroom apartment is around $3,200/month. Salary transparency lets candidates compare offers, negotiate effectively, and align compensation with the cost of living and local market rates.

Unit Assistant

Company: Kaiser Permanente

Location: San Rafael, California

Posted Aug 24, 2025

Clinical Pharmacist Full Time Days NCB

Company: North Central Baptist Hospitals

Location: San Antonio, TX

Posted Aug 24, 2025

The Clinical Pharmacist is responsible for maintaining pharmaceutical dispensing functions, including clinical review functions, in accordance with all legal…

AI Solutions Architect, Data Solutions & Initiatives

Company: Apple

Location: Cupertino, CA

Posted Aug 24, 2025

We are seeking a hands-on AI Solutions Architect with deep technical expertise in Artificial Intelligence and Generative AI who can design, prototype, and…

Pharmacy, Clinical Specialist - Pharmacy

Company: Rady Children's Hospital-San Diego

Location: San Diego, CA

Posted Aug 24, 2025

Under general supervision, the Clinical Pharmacy Specialist participates as an integral member of the multidisciplinary healthcare team, working closely with…

Software Build Engineer

Company: Apple

Location: San Diego, CA

Posted Aug 24, 2025

Demonstrate willingness to ask for clarification and context to understand the big picture - Find multiple solutions to a problem, evaluate tradeoffs, and…

Board Certified Behavioral Analyst- San Diego - EBSH Home experienced

Company: Redwood Family Care Network

Location: San Diego, CA

Posted Aug 24, 2025

Master’s degree in related field preferred, BCBA credential required. This position will require a valid California ID or Driver’s License.

Software Build Engineer

Company: Apple

Location: San Diego, CA

Posted Aug 24, 2025

Demonstrate willingness to ask for clarification and context to understand the big picture - Find multiple solutions to a problem, evaluate tradeoffs, and…

Frequently Asked Questions

What types of tech jobs are available in San Mateo, CA?
San Mateo hosts roles in software engineering (full‑stack, mobile, data), product management, UX/UI design, DevOps, AI/ML research, cybersecurity, cloud architecture, fintech development, healthtech R&D, and biotech software support.
Are tech jobs in San Mateo remote, on‑site, or hybrid?
The majority (≈65%) of openings require on‑site presence in Downtown or Hillsdale, but 30% offer hybrid schedules and 5% are fully remote, reflecting the city’s mix of legacy firms and agile startups.
Who are the major employers in San Mateo?
Key employers include Salesforce, Adobe, Twitter, Uber, Lyft, Palantir, and regional offices of Google, LinkedIn, and Meta. Startups such as Scribe, Sinequa, and local biotech incubator companies also dominate hiring.
What are the salary expectations for tech roles in San Mateo?
Base salaries for software engineers begin at $110,000 and average $150,000–$170,000 for senior roles; product managers average $135,000–$160,000; data scientists average $145,000; cybersecurity roles average $140,000–$165,000. Total compensation often includes bonuses, RSUs, and benefits.
What should I know before relocating to San Mateo for tech work?
Plan for high housing costs—factor in $3,200 monthly rent or $1.4 million median home price. Evaluate commute options: BART, Caltrain, and local bus routes serve downtown. Research local coworking spaces, networking events, and community groups like San Mateo Tech Meetups to ease transition.

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