Tech Jobs in San Mateo, CA

1,130,501 open positions · Updated daily

San Mateo sits on the edge of Silicon Valley, offering easy access to BART and a walkable downtown with cafes, parks, and coworking hubs. The city hosts a vibrant mix of startups, Fortune 500 tech firms, and research labs, drawing talent from Stanford, UC Berkeley, and major tech schools nearby.

Tech roles range from cloud infrastructure and AI research to fintech product management and cybersecurity architecture. Companies such as Salesforce, Adobe, Twitter, and Uber maintain regional offices, while emerging startups like Scribe and Sinequa build products in healthtech and search AI. Biotech firms in nearby Redwood City and biotech incubators in San Mateo’s Hillsdale area further diversify the ecosystem.

Living costs are high: median home price exceeds $1.4 million and the average rent for a 1‑bedroom apartment is around $3,200/month. Salary transparency lets candidates compare offers, negotiate effectively, and align compensation with the cost of living and local market rates.

Registered Nurse, Pediatric CVICU

Company: CHRISTUS Health (IHE/Hosted)

Location: San Antonio, TX

Posted Aug 21, 2025

Continues to develop the ability to cope with and manage contingencies of clinical nursing. Addresses increasingly complex psychological, emotional, cultural,…

Sr. IT Security Analyst

Company: Omnivision Technologies

Location: Santa Clara, CA

Posted Aug 21, 2025

Experience working with information security teams and functions, such as security engineering, security operations centers, vulnerability assessment,…

Travel RN Infection Control Practitioner

Company: Cambay Healthcare LLC

Location: San Diego, CA

Posted Aug 21, 2025

Active California RN License and BLS certification. BLS and Infection Control certifications required. Investigate outbreaks and recommend preventive measures.

Senior Tax Associate

Company: Distinct Recruitment

Location: San Antonio, TX

Posted Aug 21, 2025

Help with management and strategy as part of a wider team. Or send me a message or connection request on LinkedIn and we’ll pick things up from there.

Part-time Preschool Teacher

Company: Aspen Leaf Preschool

Location: San Diego, CA

Posted Aug 21, 2025

Must have current first aid and CPR certification. Education: Must have at least 12 post-secondary semester units in early childhood education from an…

Class A Driver - Days - San Antonio

Company: Johnson Brothers - Maverick of Texas

Location: San Antonio, TX

Posted Aug 21, 2025

Minimum 3 year driving experience (tractor/trailer) / 5 years preferred. Must possess a valid Class A CDL. Unload the pallet of product at each respective cross…

Teacher - SDC ESN 4th - 6th - Zanker Elementary School - 010556

Company: Milpitas Unified School District

Location: Milpitas, CA

Posted Aug 21, 2025

A valid California driver=s license. Evaluate each student=s social and academic needs and develop and Individual Educational Program (IEP).

Call Center Representative - Onsite Work Only - NO REMOTE WORK

Company: Magellan Solutions USA

Location: Palo Alto, CA

Posted Aug 21, 2025

Answers incoming calls and communicates with clients with respect, courtesy, empathy, tact, and professionalism. Friday and Saturday: 11:00 pm - 7:00 am.

Accountant (On-Site)

Company: Wilshire Law Firm

Location: Los Angeles, CA

Posted Aug 21, 2025

Collaborate with the outside CPA firm on tax filings and state deadline requirements. You will handle accounting functions ranging from reconciliations and…

Staff Accountant

Company: AppleOne

Location: Los Angeles, CA

Posted Aug 21, 2025

For temporary assignments lasting 13 weeks or longer, the Company is pleased to offer major medical, dental, vision, 401k and any statutory sick pay where…

Custodian (Days)

Company: The DoSeum

Location: San Antonio, TX

Posted Aug 21, 2025

*Dependability *- Follows instructions, responds to management direction; Takes responsibility for own actions. High school diploma or G.E.D.

Custodian (Nights) - Full-Time

Company: The DoSeum

Location: San Antonio, TX

Posted Aug 21, 2025

*Dependability *- Follows instructions, responds to management direction; Takes responsibility for own actions. High school diploma or G.E.D.

Frequently Asked Questions

What types of tech jobs are available in San Mateo, CA?
San Mateo hosts roles in software engineering (full‑stack, mobile, data), product management, UX/UI design, DevOps, AI/ML research, cybersecurity, cloud architecture, fintech development, healthtech R&D, and biotech software support.
Are tech jobs in San Mateo remote, on‑site, or hybrid?
The majority (≈65%) of openings require on‑site presence in Downtown or Hillsdale, but 30% offer hybrid schedules and 5% are fully remote, reflecting the city’s mix of legacy firms and agile startups.
Who are the major employers in San Mateo?
Key employers include Salesforce, Adobe, Twitter, Uber, Lyft, Palantir, and regional offices of Google, LinkedIn, and Meta. Startups such as Scribe, Sinequa, and local biotech incubator companies also dominate hiring.
What are the salary expectations for tech roles in San Mateo?
Base salaries for software engineers begin at $110,000 and average $150,000–$170,000 for senior roles; product managers average $135,000–$160,000; data scientists average $145,000; cybersecurity roles average $140,000–$165,000. Total compensation often includes bonuses, RSUs, and benefits.
What should I know before relocating to San Mateo for tech work?
Plan for high housing costs—factor in $3,200 monthly rent or $1.4 million median home price. Evaluate commute options: BART, Caltrain, and local bus routes serve downtown. Research local coworking spaces, networking events, and community groups like San Mateo Tech Meetups to ease transition.

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