Tech Jobs in San Mateo, CA

1,130,899 open positions · Updated daily

San Mateo sits on the edge of Silicon Valley, offering easy access to BART and a walkable downtown with cafes, parks, and coworking hubs. The city hosts a vibrant mix of startups, Fortune 500 tech firms, and research labs, drawing talent from Stanford, UC Berkeley, and major tech schools nearby.

Tech roles range from cloud infrastructure and AI research to fintech product management and cybersecurity architecture. Companies such as Salesforce, Adobe, Twitter, and Uber maintain regional offices, while emerging startups like Scribe and Sinequa build products in healthtech and search AI. Biotech firms in nearby Redwood City and biotech incubators in San Mateo’s Hillsdale area further diversify the ecosystem.

Living costs are high: median home price exceeds $1.4 million and the average rent for a 1‑bedroom apartment is around $3,200/month. Salary transparency lets candidates compare offers, negotiate effectively, and align compensation with the cost of living and local market rates.

Middle School Special Ed Teacher | San Diego, California

Company: ProCare Therapy

Location: San Diego, CA

Posted Aug 16, 2025

Bachelor's or Master's degree in Special Education, active Special Education Teacher license and minimum 1+ years Special Education Teacher experience required.

Cath Lab RN Travel Assignment in Glendale, CA

Company: Soliant

Location: Glendale, CA

Posted Aug 16, 2025

Bachelor of Science in Nursing (BSN) degree, active registered nurse (RN) license and minimum 1+ years RN experience required. California RN license in hand.

Senior Analyst, Cyber Defense

Company: USC

Location: Los Angeles, CA

Posted Aug 16, 2025

A bachelor’s degree in information science or computer science or computer engineering or in related field(s); or combined experience/education as substitute…

Truck Driver

Company: Regiment Transport LLC

Location: Los Angeles, CA

Posted Aug 16, 2025

Minimum 3 years driving experience. Hello, I am looking for a driver with HAZMAT ENDORSEMENT along with Tankers. Experience needed but not require (in tankers).

Outpatient Staff Pharmacist PRN (Ongoing Need) Location: East Palo Alto CA

Company: RPh on the Go

Location: Fremont, CA

Posted Aug 16, 2025

Active, clear California Pharmacist license. Ensure compliance with all federal and state pharmacy laws and regulations.

Full-Time Pharmacist Contract-to-Hire Mail Order/Retail Background Chula Vista, CA (13+ Weeks)

Company: RPh on the Go

Location: San Diego, CA

Posted Aug 16, 2025

Doctor of Pharmacy (PharmD) degree, active Pharmacist license, and minimum 1+ years Pharmacist experience required.

CDL-A Regional Truck Driver - 3 Months Experience Required

Company: C.R. England

Location: Glendale, CA

Posted Aug 16, 2025

Top-of-the-line trucks with automatic transmission pulling 53-ft trailers. Valid CDL-A plus 3+ months of Class A CDL experience required.

Chef de Cuisine

Company: Menlo Circus Club

Location: Atherton, CA

Posted Aug 16, 2025

Ensure the kitchen's cleanliness and adherence to local and state health regulations. Utilize P&L statements as tools to maintain appropriate cost and revenue…

Assistant Controller - SCMG Finance - Sharp Corporate - Day Shift - Full Time

Company: Sharp Healthcare

Location: San Diego, CA

Posted Aug 16, 2025

Coordinates the filing of annual federal and state tax returns, working with the tax preparers, including calculation of annual deferred tax provision.

Visual + Motion Design Lead

Company: Ford Motor Company

Location: Palo Alto, CA

Posted Aug 16, 2025

Bachelor's degree in graphic design, 3D animation, motion, digital product design or related field or a combination of education and equivalent experience.

CDL-A Regional Truck Driver - 3 Months Experience Required

Company: C.R. England

Location: Los Angeles, CA

Posted Aug 16, 2025

Top-of-the-line trucks with automatic transmission pulling 53-ft trailers. Valid CDL-A plus 3+ months of Class A CDL experience required.

Truck Driver CDL A Local Home Daily

Company: Ryder

Location: San Antonio, TX

Posted Aug 16, 2025

Ensuring compliance with applicable federal and/or state laws, regulations, and/or agency rules, standards and guidelines. Ryder Drivers are Paid Weekly.

Frequently Asked Questions

What types of tech jobs are available in San Mateo, CA?
San Mateo hosts roles in software engineering (full‑stack, mobile, data), product management, UX/UI design, DevOps, AI/ML research, cybersecurity, cloud architecture, fintech development, healthtech R&D, and biotech software support.
Are tech jobs in San Mateo remote, on‑site, or hybrid?
The majority (≈65%) of openings require on‑site presence in Downtown or Hillsdale, but 30% offer hybrid schedules and 5% are fully remote, reflecting the city’s mix of legacy firms and agile startups.
Who are the major employers in San Mateo?
Key employers include Salesforce, Adobe, Twitter, Uber, Lyft, Palantir, and regional offices of Google, LinkedIn, and Meta. Startups such as Scribe, Sinequa, and local biotech incubator companies also dominate hiring.
What are the salary expectations for tech roles in San Mateo?
Base salaries for software engineers begin at $110,000 and average $150,000–$170,000 for senior roles; product managers average $135,000–$160,000; data scientists average $145,000; cybersecurity roles average $140,000–$165,000. Total compensation often includes bonuses, RSUs, and benefits.
What should I know before relocating to San Mateo for tech work?
Plan for high housing costs—factor in $3,200 monthly rent or $1.4 million median home price. Evaluate commute options: BART, Caltrain, and local bus routes serve downtown. Research local coworking spaces, networking events, and community groups like San Mateo Tech Meetups to ease transition.

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