Remote-First Company Jobs in USA

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Looking for Remote-First Company jobs in USA? Browse our curated listings with transparent salary information to find the perfect Remote-First Company position in the USA area.

Senior Clinical Research Associate - Oncology/Respiratory

Company: ClinChoice

Location: USA

Posted Jan 31, 2025

ClinChoice, a global full-service CRO, is seeking a Senior Clinical Research Associate to join their team on a permanent basis. The role involves managing 23 trials, conducting site management, and working with a diverse client base. Applicants must have experience in oncology or respiratory clinical trials. The position offers a fulfilling career, excellent work-life balance, and the opportunity to make a difference in people's lives. Key responsibilities include monitoring clinical projects, training site staff, and ensuring reliable clinical data. The ideal candidate should have a university degree in a scientific, medical, or paramedical discipline, proven CRA experience, and strong knowledge of clinical trial operations and regulatory requirements. Fluency in English and local languages, proficiency in Microsoft Office, and willingness to travel are also required.

Client Marketing Manager

Company: COMPLY

Location: USA

Posted Jan 31, 2025

COMPLY is a high-growth organization that prides itself on being a champion for compliance professionals. With over 350 professionals worldwide, they offer comprehensive benefits and remote work flexibility. They are seeking an experienced Client Marketing Manager to craft and execute targeted marketing strategies, enhance client engagement, and drive loyalty, retention, and revenue growth. The role involves creating segment-specific campaigns, collaborating with content and product marketing teams, and leveraging client insights to tailor campaigns. The ideal candidate should have 5+ years of experience in client or customer marketing, preferably within B2B SaaS or high-tech industries, and a strategic, collaborative mindset. Familiarity with ABM strategies and AI is a plus. COMPLY offers a comprehensive benefits package, including full medical, dental, and vision coverage, unlimited PTO, and a virtual onboarding experience with a stipend for work-from-home setup.

Senior Business Systems Analyst, Legal Operations

Company: HubSpot

Location: USA

Posted Jan 31, 2025

HubSpot's Legal and Compliance team is seeking a Senior Business Systems Analyst to drive operational excellence and technology roadmap for scaling pain points. The role involves implementing core technologies, improving processes, leveraging data for decision-making, and collaborating with various teams. The ideal candidate should have expertise in CLM systems, document operations, and enterprise service management tools, with a strong understanding of SQL and data. They should thrive in a fast-paced setting, have excellent communication skills, and be passionate about collaboration and effective communication. The cash compensation range is $115,400 - $184,600 annually.

Senior Software Engineer, Integrated Knowledge Management

Company: Airbnb

Location: USA

Posted Jan 31, 2025

Airbnb is seeking a Senior Software Engineer for the Integrated Knowledge Management team. The role involves developing solutions to scale and optimize content and knowledge indexing, retrieval, and ranking across all of Airbnb. The engineer will collaborate with various teams to design and build end-to-end product solutions to improve Airbnb's customer service experience. The ideal candidate should have 5+ years of industry engineering experience, a degree in CS or a related field, and expertise in leveraging OpenSearch, Elasticsearch, or similar technologies for content indexing, retrieval, and ranking applications. Proficiency in backend JVM languages and experience in building high-performance, scalable, and fault-tolerant backend systems are required. Bonus points for understanding of ML search and retrieval models and industry experience in building end-to-end Machine Learning products.

Google Cloud Security Architect

Company: GuidePoint Security

Location: USA

Posted Jan 31, 2025

The Google Cloud Security Architect is responsible for designing, implementing, and securing customers' Google Cloud and Google Cloud SecOps infrastructure. This role involves developing cloud strategies, architecting cloud solutions, and ensuring the security, scalability, and reliability of a Google Cloud and Google Cloud SecOps environment. The individual will operate primarily in a remote customer-facing role, integrating cloud technologies into existing or new environments while providing expertise in cloud computing to drive business efficiency and innovation. Responsibilities include evaluating existing cloud infrastructure, recommending improvements, and implementing Google Cloud and Google Cloud SecOps best practices. The candidate will work with infrastructure team members to provide secure configurations within the Google Cloud and Google Cloud SecOps infrastructure.

Talent Management Operations Specialist

Company: General Motors

Location: USA

Posted Jan 31, 2025

General Motors is seeking an experienced Talent Management Operations Specialist for a remote role based in Atlanta, Austin, Detroit, Warren Pontiac, Milford, or Mountain View. The role involves designing, building, and implementing new talent processes, driving the execution of existing talent programs, and collaborating with various teams to deliver GM's talent strategy. The ideal candidate should have 57+ years of experience in HR, talent management, or organizational development, a Bachelor's degree, and expertise in talent practices delivered by Workday. Strong communication skills, problem-solving abilities, and proficiency in data analysis are required. The role offers a competitive salary range of $85,100-$158,000, bonus potential, and comprehensive benefits.

Senior Cloud Engineer

Company: Contrast Security

Location: USA

Posted Jan 31, 2025

Contrast Security is seeking a Cloud Engineer with 8+ years of experience in DevOps or SRE roles. The ideal candidate should have a strong background in AWS, Terraform, Kubernetes, and RESTful API development. They should be passionate about automation, observability, and making the Internet a safer place. The role involves designing and building automated, elastic, and reliable cloud-based infrastructure, as well as debugging production issues and participating in on-call rotations. Contrast Security offers a competitive salary, comprehensive benefits, and the opportunity to work on cutting-edge software security solutions.

Senior Manager, Corporate and Technical Accounting

Company: Coursera

Location: USA

Posted Jan 31, 2025

Coursera is seeking a highly motivated professional with strong technical accounting experience to oversee the global monthly closing process, manage a high-performing accounting team, and collaborate with various business partners. The role requires a deep working knowledge of US GAAP, prior experience managing teams, and proficiency in NetSuite or other major ERP. The targeted hiring base salary range is between $149,000 and $158,000.

AI Web Search Evaluator - English (United States)

Company: Welo Data

Location: USA

Posted Jan 31, 2025

This job posting is for a remote, part-time position as a Search Quality Rater. The role involves evaluating and rating the effectiveness of search engine results, providing insights on relevance and quality, and offering feedback to improve algorithm performance. The ideal candidate should be familiar with online search engines, enjoy researching topics online, and have a strong understanding of pop culture in the US. The position offers a competitive pay rate of $1450 per hour, flexible hours, and potential for extension. Benefits include medical, dental, vision insurance, HSA, life insurance, accident critical illness hospital indemnity insurance, and a 401k retirement plan. The role is currently hiring in several US states and requires fluency in English, a reliable computer system, and internet connection. The official title of the position is Search Quality Rater.

Commercial Counsel

Company: Stripe

Location: USA

Posted Jan 31, 2025

Stripe, a global technology company, is seeking an exceptional transactional lawyer to join their commercial legal team in North America. The role involves supporting the AMER Sales team, working closely with Product Legal, and contributing to the build-out of Stripe's commercial legal infrastructure. The ideal candidate is intellectually curious, a self-starter, a clear communicator, a natural collaborator, and has relevant legal experience. Preferred qualifications include experience in payment or fintech industries, inhouse experience advising high growth companies, and working knowledge of data protection laws.

Senior Manager - Brand & Creative

Company: COMPLY

Location: USA

Posted Jan 31, 2025

COMPLY is a high-growth organization that prides itself on being the champion for compliance professionals. With over 350 professionals worldwide, they serve more than 7000 clients globally through various solutions. They are seeking a Senior Manager Brand and Creative to elevate the COMPLY brand through exceptional design, storytelling, and visual communication. The role involves leading brand strategy, creative design, content development, and managing a design system and template library. The ideal candidate should have 7+ years of experience in brand and creative roles, mastery of design tools, and proven experience in building and evolving brand identities for B2B organizations. COMPLY offers a comprehensive benefits package, 100 remote flexibility, and a high-growth startup environment.

Product Manager IV

Company: Kueski

Location: USA

Posted Jan 31, 2025

Kueski is a leading buy now pay later and online consumer credit platform in Latin America, recognized for its innovative financial services. The company was the first to introduce BNPL on Amazon Mexico and was named the top BNPL platform by Fintech Breakthrough in 2023. Kueski also ranks as one of Mexico's most ethical companies and one of the Best Companies for Female Talent. The company culture is geared towards innovation, collaboration, and impact, fostering a strong diverse and inclusive environment. The role of a Product Manager IV at Kueski involves overseeing the entire product lifecycle, from conceptualization to launch, and requires a blend of technical knowledge, business acumen, and leadership skills. Key responsibilities include market analysis, product vision and strategy, roadmap planning, feature definition, cross-functional leadership, project management, performance monitoring, customer engagement, stakeholder communication, and team development.

Frequently Asked Questions

What are typical salary ranges by seniority for Remote-First roles?
Junior Engineer: $70k‑$90k; Mid‑Level: $90k‑$120k; Senior Engineer: $120k‑$160k; Lead Engineer: $160k‑$200k; Principal Engineer: $200k‑$250k. Remote‑First companies often add a 5–10% cost‑of‑living adjustment for high‑cost regions, making these bands competitive globally.
What skills and certifications are required for Remote-First positions?
Technical: AWS Certified Solutions Architect, Google Cloud Professional Data Engineer, Terraform Associate, Docker Certified Associate, Kubernetes Administrator, React, Node.js, Python, Go. Soft: asynchronous communication, remote collaboration with Slack/Zoom, documentation in Confluence, and experience with GitHub Actions for CI/CD.
Is remote work fully available for all positions?
All listed roles are 100% remote with no on‑site requirement. Companies provide a 24‑hour coverage model, allowing team members in different time zones to overlap for core meetings and support windows.
What career progression paths exist in Remote-First companies?
Typical path: Junior → Mid → Senior → Lead → Technical Manager → VP. Promotion criteria include delivery quality, cross‑team mentorship, contribution to open‑source projects, and participation in internal learning hubs like remote‑first bootcamps.
What industry trends affect Remote-First companies today?
AI‑driven collaboration tools, outcome‑based performance metrics, distributed DevOps practices, emphasis on continuous learning, and remote‑first security frameworks (Zero Trust, VPNless access) are shaping the landscape. Companies are investing in these areas to reduce latency, increase resilience, and attract top talent.

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