Remote-First Company Jobs in USA

456,353 open positions · Updated daily

Looking for Remote-First Company jobs in USA? Browse our curated listings with transparent salary information to find the perfect Remote-First Company position in the USA area.

Senior Cloud Platform Engineer

Company: Mapbox

Location: USA

Posted Dec 11, 2025

Mapbox is a leading real-time location platform with a global team supporting over 700 engineers. They focus on cloud-native solutions, infrastructure as code, and scalable CI/CD pipelines for developers.

Director of Strategic Partnerships

Company: Gravie

Location: USA

Posted Dec 11, 2025

Gravie seeks a Director of Strategic Partnerships to expand their healthcare solutions network. The role involves managing partner relationships, driving growth, and aligning with ICHRA/level-funded goals. The company offers competitive compensation, benefits, and a mission-driven environment.

Strategic Partnership Director

Company: International Medical Group

Location: USA

Posted Dec 10, 2025

IMG seeks a Strategic Partnership Director to drive growth in travel insurance through market insights, partner management, and competitive analysis. The role involves managing digital platforms, enhancing partnerships, and ensuring IMG's competitiveness. Qualifications include a bachelor's degree or experience in travel insurance, digital distribution, and strong analytical skills.

Variant Scientist II - Invitae

Company: labcorp

Location: USA

Posted Dec 11, 2025

Invitae seeks a Variant Scientist for a remote or San Francisco-based role with competitive salary, benefits, and opportunities for growth. The position involves variant interpretation, genetic curation, and collaboration in a dynamic environment.

Transformation Advisor

Company: Guidehouse

Location: USA

Posted Dec 11, 2025

This job posting describes a Transformation Advisor role focused on guiding federal clients through IWMS modernization efforts. Responsibilities include developing strategic roadmaps, configuring systems, and ensuring compliance with security standards. The position requires 15 years of consulting experience and an active secret clearance, with competitive compensation ranging from $149,000 to $248,000. Benefits include comprehensive health insurance, retirement plans, and flexible work arrangements.

Continuous Improvement Leader

Company: Fortive

Location: USA

Posted Dec 10, 2025

The text emphasizes driving continuous improvement, mentoring teams, promoting FBS culture, and collaborating with leaders to enhance business results through lean methodologies and cross-functional teamwork.

Senior Salesforce Administrator

Company: labcorp

Location: USA

Posted Dec 11, 2025

Labcorp is seeking a Senior Salesforce Administrator to join their dynamic team, offering competitive pay, comprehensive benefits, and opportunities to work with cutting-edge technology. The role involves managing CRM systems, collaborating with cross-functional teams, and contributing to innovative healthcare solutions. The company emphasizes work-life balance, global development, and a commitment to improving health through advanced diagnostics and drug development.

Principal Statistical Programmer Consultant (Oncology)

Company: ClinChoice

Location: USA

Posted Dec 11, 2025

This job posting seeks a Principal Statistical Programmer Consultant for a global CRO client, highlighting responsibilities in oncology trials, regulatory submissions, and leadership roles. The position emphasizes expertise in SAS, CDISC standards, and cross-functional collaboration. ClinChoice, a 28-year-old CRO, promotes diversity and continuous training, offering a mix of security and career opportunities in a global environment.

Clinical R Programmer (SDTM/ADaM)

Company: ClinChoice

Location: USA

Posted Dec 11, 2025

This job posting seeks a Clinical R Programmer Consultant with expertise in SDTM and ADaM datasets, R programming, and CDISC standards. The role involves collaborating with cross-functional teams, ensuring regulatory compliance, and contributing to automation initiatives. ClinChoice, a global CRO, emphasizes training, diversity, and high-quality clinical development solutions.

Server Admin Lead

Company: Guidehouse

Location: USA

Posted Dec 11, 2025

This job posting outlines a Systems Engineer role with responsibilities in scheduler management and security. It highlights required skills, benefits, and a comprehensive rewards package.

Human Factors Engineer I

Company: iRhythm

Location: USA

Posted Dec 10, 2025

iRhythm offers a Human Factors Engineer role with opportunities for career growth and impactful work in cardiac health tech. The position involves usability studies, cross-functional collaboration, and compliance with medical device regulations. The company emphasizes innovation, patient-centric design, and global health impact while highlighting competitive compensation and remote work flexibility.

Director of Product - Maps

Company: Mapbox

Location: USA

Posted Dec 11, 2025

Mapbox is a leading real-time location platform with 4M developers, offering tools for businesses. The role involves product strategy for maps, focusing on innovation and customer experience.

Frequently Asked Questions

What are typical salary ranges by seniority for Remote-First roles?
Junior Engineer: $70k‑$90k; Mid‑Level: $90k‑$120k; Senior Engineer: $120k‑$160k; Lead Engineer: $160k‑$200k; Principal Engineer: $200k‑$250k. Remote‑First companies often add a 5–10% cost‑of‑living adjustment for high‑cost regions, making these bands competitive globally.
What skills and certifications are required for Remote-First positions?
Technical: AWS Certified Solutions Architect, Google Cloud Professional Data Engineer, Terraform Associate, Docker Certified Associate, Kubernetes Administrator, React, Node.js, Python, Go. Soft: asynchronous communication, remote collaboration with Slack/Zoom, documentation in Confluence, and experience with GitHub Actions for CI/CD.
Is remote work fully available for all positions?
All listed roles are 100% remote with no on‑site requirement. Companies provide a 24‑hour coverage model, allowing team members in different time zones to overlap for core meetings and support windows.
What career progression paths exist in Remote-First companies?
Typical path: Junior → Mid → Senior → Lead → Technical Manager → VP. Promotion criteria include delivery quality, cross‑team mentorship, contribution to open‑source projects, and participation in internal learning hubs like remote‑first bootcamps.
What industry trends affect Remote-First companies today?
AI‑driven collaboration tools, outcome‑based performance metrics, distributed DevOps practices, emphasis on continuous learning, and remote‑first security frameworks (Zero Trust, VPNless access) are shaping the landscape. Companies are investing in these areas to reduce latency, increase resilience, and attract top talent.

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