Jobs at Click Therapeutics
249,921 open positions
Senior Manager, Data Sciences
Company: Dianthus Therapeutics
Location: Remote
Posted Feb 23, 2024
Highest levels of professionalism, confidence, personal values and ethical standards. Highly organized and detail-oriented. Life Sciences experience is a plus. Experience University degree required within a relevant discipline. Skilled in management of timelines and coordination with internal and resources to efficiently reach deliverables Comprehensive understanding of DM related systems and technologies Comprehensive knowledge of drug development and clinical research processes, GCP guidelines and regulations related to clinical data management Self-motivated and able to work autonomously, as well as a member of a high-functioning and collaborative team. Strong verbal and written communication skills with an ability to build relationships internally and externally. Key Responsibilities Cultivate and manage relationships with DM partners (eg, CROs and other vendors) and cross functional team members to ensure data are reviewed and delivered with high quality, are on-time and within scope Accountable for ensuring timeliness of data deliverables are met and align with company goals Monitor and track data-related timelines and deliverables and serve as central point of communication for other cross-functional team members Document data workflows for assigned studies, ensuring transfers occur based on study-specific needs Support the development of standard operating procedures (SOPs) and processes with a focus on continuous improvement and increased efficiency Maintain data integrity in compliance with GCP, relevant SOPs and regulatory requirements by reviewing relevant data processes, documents, outputs and filing documentation in the trial master file (TMF). Other related duties as may be determined or assigned. You will report to the Director, Data Sciences and will independently support all active programs to ensure complete, accurate, high quality and regulatory compliant data in support of internal or external stakeholders, study reports, publications and regulatory submissions. This includes coordination and timing for data transfers, internal and external data reviews, data deliverables for interim/final analyses, DSMB meetings and any other data-related deliverables.
Associate Director/Director, Global Program Management
Company: Scorpion Therapeutics
Location: Boston, MA
Posted Feb 21, 2024
We do not discriminate for reasons of race, color, religion, gender, national origin, age, sexual orientation, marital or veteran status, disability, or any other legally protected status. Beginning October 13, 2021, Scorpion Therapeutics requires all new hires to be fully vaccinated against COVID-19. They will identify project risks, develop mitigation approaches, and manage variances in terms of time, budget and quality. If you are unable to receive the vaccine due to a disability or serious medical condition, or because of your sincerely held religious beliefs, you will have an opportunity to request a reasonable accommodation. Responsibilities: Independently manage one to two early phase development projects Aligned with the strategy, build the operational plan, manage, coordinate and track all project-activities to advance development projects Manage, monitor and report on project progress, budgets, and resources With Core Teams, identify and request resources required for the project and ensuring resources are assigned and aligned Collaborate effectively with clinical, regulatory, CMC, non-clinical and other cross-functional team members to drive project delivery Provide clear communication to stakeholders and team members on project status/issues and documents/presents to management Ensure communications within and from the team are clear and effective, meetings have clear purpose and objectives, and that conflict is surfaced and resolved Monitor project milestones and deliverables in accordance with Corporate objectives Collaborate w/ team members to identify and manage external vendors and consultants Ensure compliance with internal and external regulations Develop best practices and strategies for project management Requirements: Bachelor's degree in a related field A minimum of five (5) years in the (bio)pharmaceutical industry. Demonstrated ability to work effectively in a team setting, including demonstrated ability to build trust among team members and find ways to optimally work Experience working in a partnership a plus Excellent organizational, communication and problem-solving skills; demonstrated ability to speak up appropriately and to raise issues to teams, partners and senior management Ability to work in a fast-paced environment Knowledge of FDA regulations and GCP/ICH guidelines a plus Proficient in MS Office and project management software Project management certification (PMP) and/or formal coursework/training in project management is a plus Scorpion Therapeutics Inc. is an Equal Opportunity Employer who strives to create and maintain a diverse working environment. A minimum of one (1) years of experience in program/project management or a related role Demonstrated leadership and ethics; demonstrated ability to hold others accountable for delivery; ability to listen, interpret and respond to critical information. The candidate is expected to provide project management leadership to drive productive partnerships and cross-functional project teams, with sufficient influence and project management mastery to take on challenging assignments. This individual should have excellent organizational, communication and problem-solving skills and be able to work in a fast-paced environment. Job Summary: We are looking for an experienced Associate Director/Director, Global Program Manager to join our growing team.
Quality Assurance, CMC (Manager)
Company: Karuna Therapeutics
Location: Boston, MA
Posted Feb 21, 2024
<p><strong>Position Quality Assurance CMC Manager<strong><p> <p><br ><p><p><strong>Position Summary<strong><p> <p>Karuna is seeking an experienced and motivated individual to join our Quality Assurance team as Manager CMC Quality Assurance to support drug development from Phase 1 to commercialization Reporting to the Associate Director Quality Assurance CMC this position is responsible for managing reviewing and approving quality documents from Contract Manufacturing Organizations and Contract Testing Laboratories for manufacturing testing validation and disposition of clinical and commercial products for human use This position will work closely with CMC regulatory affairs and other functional teams<p> <p><br ><p><p><strong>Responsibilities<strong><p> <ul><li>Ensures compliance to cGMP policies and procedures for documentation resulting from manufacturing operations of clinical and commercial small molecule API and drug product<li> <li>Provides Quality oversight of protocols starting material and finished product specifications API and DP manufacturing analytical and stability reports<li> <li>Ensures corporate readiness towards regulatory CMC inspections<li> <li>Ensures data integrity in GMP documentation from manufacturing analytical and stability studies<li> <li>Performs disposition activities for manufactured products in support of CommercialClinical Product including Master Batch Record review Executed Batch Record review resolution of commentsissues and Certificate of Analysis review<li> <li>Performs assessments and QA review of Change Controls deviations root cause analysis and product impact assessments and investigations including OOS investigations for commercial and clinical products<li> <li>Reviews product release and stability data<li> <li>Supports other QA operation or compliance activities as needed<li> <ul><p><br ><p><p><strong>Required Qualifications<strong><p> <ul><li>BSBA in Chemistry Biology Pharmaceutics or other science related field<li> <li>Minimum six years of experience within the pharmaceutical industry and in a Quality Assurance role<li> <li>Knowledge of FDA EU ICH requirements for GMP and related areas eg 21 CFR 211 Part 11 Annex 11 ICH Q7 etc<li> <li>Experience in reviewing Specifications MBRs EBRs stability protocols method validation protocols and reports etc<li> <li>Excellent verbal and written skills allowing for an open and effective dialogue throughout the company<li> <li>Attention to detail and quality are critical to success<li> <li>Highly accountable for the results and outcomes of their responsibilities and understands the impact of their efforts results and attitudes on others<li> <li>Uses teamwork to work cooperatively toward the most effective solutions championing the best ideas of team members and assisting where help is needed yet is capable of highly independent work when efficiency is required<li> <li>Resultsoriented individual who is highly motivated decisive flexible in thought and has the creativity to excel in and contribute to a rapidly growing company<li> <li>Forward thinking mindset with the ability to manage multiple projects and identify and resolve issues<li> <li>Broad experience in an emerging publicly traded company environment is a plus<li> <ul><p><br ><br ><p><p><u>The successful candidate will also embody our values<u><p> <p><strong> <strong><p> <p><strong>Our purpose is to create value for those we have the privilege to serve<strong><p> <ul><li>We take pride in our work<li> <li>We keep our promises and deliver<li> <li>We are driven to meaningfully innovate<li> <li>We succeed through inclusion and teamwork<li> <ul><p><strong> <strong><p> <p>Karuna Therapeutics is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race color religion sex sexual orientation age gender identity or gender expression national origin disability or veteran status<p> <p><br ><br ><br ><br ><br ><br ><br ><p><p>LIHybrid<p>
Scientist, Platform Proteomics
Company: Rezo Therapeutics
Location: San Francisco, CA
Posted Feb 21, 2024
<p><b>About Rezo Therapeutics<b><p> <p>Rezo is a different kind of biopharma company Our mission is to dramatically increase the success rate of drug development by building a diseaseagnostic fullyintegrated network biology platform that will redefine our understanding of human disease and ability to treat it <p> <p><br ><p> <p>Our Founders and members of the Board are a group of esteemed worldclass scientists from the University of California San Francisco Nevan Krogan Kevan Shokat Sourav Bandyopadhyay Natalia Jura as well as renowned biotech executives George Scangos and Norbert Bischofberger These leaders bring with them a strong track record of amazing discoveries and scientific breakthroughs leading to very successful companies and many FDA approved drugs <p> <p><br ><p> <p>Capitalizing on our Series A of $78M from toptier investors we are leveraging a unique integrated approach combining capabilities in genetics proteomics structural biology and AI to generate deep biological insights and novel therapeutic approaches<p> <p><br ><p> <p>Located in San Franciscos vibrant Mission Bay neighborhood Rezo is in close proximity to UCSF numerous urban amenities and outdoor recreational opportunities We recognize that realizing our mission depends as much on our people as it does on our science and are building a workplace that fosters collaboration respect and diversity where contributing to your teams success is valued as highly as individual achievements If youre passionate about team science and breaking down barriers to progress in drug development please consider joining us <p> <p><br ><p> <p><b>The Opportunity <b><p> <p>We are seeking a highly enthusiastic and motivated Scientist to join our Proteomics team The successful candidate will have a deep understanding of stateoftheart mass spectrometers and software to analyze complex data In this role you will act as the conduit between analytical execution structural biology and chemoproteomics Becoming a member of this team is an excellent opportunity to join Rezo at an early stage and help build the Platform function and the company from the ground up <p> <p><br ><p> <p><b>What Youll Do<b> <p><ul><li>Operate and maintain a growing suite of stateofthe art LCMS instrumentation timsTOF HT Orbitrap QE+ Evosep One IClass<li> <li>Method development in data acquisition types DIA DDA MIDIA and sample preparation for sensitivity and reproducibility<li> <li>Work collaboratively across verticals with different teams and team members ranging from process automation chemoproteomics and structural biology<li> <li>Independently design oversee and perform wet lab proteomic experiments for affinity purification crosslinking mass spectrometry and chemoproteomics<li> <li>Maintain and organize metadata for raw processed and sample tracking<li> <li>Apply bioinformatics including search algorithms and postprocessed scoring tools to the analysis of large proteomic datasets<li> <li>Present own research updates with other team members and stay current within the field <li> <li>Keep detailed records of experimental protocols data and results<li> <li>Communicate and collaborate across a diverse interdisciplinary team<li> <ul><p><b>About You<b> <p><ul><li>PhD in proteomics chemical biology molecular biology or related field with 02 years of industry experience or MS with 6+ years of proteomicsbased mass spectrometry experience<li> <li>Interpersonal skills with an ability to interact effectively with diverse colleagues is required<li> <li>Experience in operating and maintaining timsTOF and Orbitrap mass spectrometers and liquid chromatography<li> <li>Deep understanding of how and when to perform various data acquisition schemas including DDA DIA and PRM Proven ability to optimize data acquisition for maximum performance<li> <li>Demonstrated ability in critically analyzing proteomic datasets and using established software platforms Spectronaut MaxQuant Skyline DIANN or others<li> <li>Eager to tackle difficult scientific challenges with a multidisciplinary mindset Ability to communicate successes and shortcomings of methods and results to other groups<li> <li>Able to learn design and assist in the development of new protocols and technologies at a fastpaced and evolving environment<li> <li>Strong organizational skills with the ability to handle multiple projects simultaneously is required<li> <li>Team player who thrives in a collaborative team setting<li> <ul><p> <p><p><b>Compensation at Rezo<b><p> <p>The expected starting salary range for this position based in San Francisco California is $104000 $145000 Actual starting salary will be determined based on multiple jobrelated factors including a candidates skills education and experience the level at which they are hired market demand business needs and internal parity This role is eligible for participation in our Annual Discretionary Bonus Plan based on individual and company performance and our Equity Incentive Plan subject to the terms of those plans and associated policies This position is also eligible for the benefits detailed below<p> <p><br ><p> <p><b>Benefits at Rezo<b><p> <p>Medical HMO or PPO dental and vision insurance<p> <p>Discretionary time off policy<p> <p>Company holidays including summer and winter shutdown<p> <p>401k retirement savings program<p> <p>Commuter Mass Transit Benefit Program<p> <p>Healthcare Flexible Spending Account FSA<p> <p>Dependent care Flexible Spending Account FSA<p> <p>Parental leave<p> <p>Competitive compensation<p> <p>Flexible work schedule <p> <p><br ><p> <p><b>EEOC<b><p> <p>At Rezo we value a diverse equitable inclusive workplace and provide equal employment opportunity to all persons without regard to race color sex gender identity gender expression religion age national origin ancestry citizenship physical or mental disability medical condition family care status marital status domestic partner status sexual orientation genetic information military or veteran status or any other basis protected by federal state or local laws This statement covers all facets of employment and is especially important when it comes to growing our team <b> <b><p> <p><br ><p> <p><b>If you are wondering if youll belong at Rezo or are worried that you dont meet 100 of the qualifications for this role take a chance on us and yourself please apply<b><p> <p><br ><p> <p><b>SF Fair Chance Ordinance<b><p> <p>Pursuant to the San Francisco Fair Chance Ordinance Rezo considers qualified applicants with arrest and conviction records for employment<p> <p><p>
Senior/Principal RA, Scientist, Protein Analytics
Company: Dragonfly Therapeutics
Location: Waltham
Posted Feb 21, 2024
Dragonfly Therapeutics is seeking a scientist with expertise in protein mass spectrometry to support novel immunotherapy programs. The ideal candidate should have a Ph.D. in Chemistry, Biochemistry, Biochemical Engineering, or related fields with 0-2 years of relevant industry experience or a B.S. / M.S. with 5+ years of experience. The role involves providing protein mass spectrometry support, developing biophysical and biochemical characterization, and interpreting results for cross-functional collaboration. Dragonfly Therapeutics is a clinical-stage biopharmaceutical company committed to discovering, developing, and commercializing therapies using its novel multispecific antibody technology.
Publications (Manager – Senior Manager)
Company: Karuna Therapeutics
Location: Boston, MA
Posted Feb 20, 2024
<p><strong>Position Publications Manager Senior Manager<strong><p> <p><strong> <strong><p> <p><strong>Position Summary<strong><p> <p>Karuna is seeking an experienced and motivated medical affairs professional to join our rapidly growing organization Reporting to the medical communications lead this critical position will be responsible for the creation and monitoring of highquality clinical and scientific writing deliverables for both internal and external audiences in preparation for the potential launch of our lead product candidate KarXT<p> <p><br ><p><p><strong>Responsibilities<strong><p> <ul><li>Create and support highquality scientifically accurate and consistent documents across the medical affairs team at Karuna including but not limited to presentations publications abstracts and decks<li> <li>Provide medical writing support for medical information standard response letters and information requests<li> <li>Collaborate with relevant internal functions to generate and maintain medical affairs documents and ensure objectives are aligned<li> <li>Develop and maintain a high level of knowledge in the respective therapeutic area to provide quality medical communication support<li> <li>Interpret clinical study results and collaborate with HCPs and internal stakeholders in the development of scientific communications content such as conference proceedings eg abstracts and presentations and journal manuscripts Engage in significant writing editing and project management to achieve publication goals<li> <li>Proactively prioritize identify assess and critically summarize relevant scientific and medical literature in therapeutic area Synthesize assess and communicate potential impact of key findings to stakeholders<li> <ul><p><br ><p><p><strong>Required Qualifications<strong><p> <ul><li>Bachelors degree with 68+ years experience Advanced degree MS or PhD strongly preferred<li> <li>Excellent verbal and written skills allowing for an open and effective dialogue throughout the company<li> <li>Previous medical or scientific writing experience required<li> <li>Proficiency in Microsoft Office PowerPoint Excel and experience with computer systems related to medical affairs such as VEEVA Adobe suite and publication management software is desirable<li> <li>Experience working with in crossfunctional teams within the pharmaceutical or related industry with knowledge and experience in the respective therapeutic area preferred<li> <li>Strong analytical and problemsolving skills<li> <li>Attention to detail and quality are critical to success<li> <li>Highly accountable for the results and outcomes of their responsibilities and understands the impact of their efforts results and attitudes on others<li> <li>Uses teamwork to work cooperatively toward the most effective solutions championing the best ideas of team members and assisting where help is needed yet is capable of highly independent work when efficiency is required<li> <li>Resultsoriented individual who is highly motivated decisive flexible in thought and has the creativity to excel in and contribute to a rapidly growing company<li> <li>Forward thinking mindset with the ability to manage multiple projects and identify and resolve issues<li> <li>Broad experience in an emerging publicly traded company environment is a plus<li> <ul><p><br ><br ><p><p><u>The successful candidate will also embody our values<u><p> <p><br ><p><p>Our purpose is to create value for those we have the privilege to serve<p> <ul><li>We take pride in our work<li> <li>We keep our promises and deliver<li> <li>We are driven to meaningfully innovate<li> <li>We succeed through inclusion and teamwork<li> <ul><p><strong> <strong><p> <p>Karuna Therapeutics is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race color religion sex sexual orientation age gender identity or gender expression national origin disability or veteran status<p> <p><br ><br ><br ><br ><br ><br ><br ><p><p>LIHybrid<p>
Specialty Account Manager, Sunosi (Portland, OR)
Company: Axsome Therapeutics, Inc.
Location: Portland, OR
Posted Feb 21, 2024
Axsome Therapeutics is hiring a Specialty Account Manager to promote Sunosi, a medication for improving wakefulness in adults with excessive daytime sleepiness due to obstructive sleep apnea or narcolepsy. The role involves developing a territory business plan, engaging with customers, and maximizing use of marketing resources. The ideal candidate should have a Bachelor's degree, minimum of 5 years of field customer experience, and relevant CNS/Psychiatry experience. The anticipated salary range is $110,000 - $150,000.
Strategic Sourcing (Manager – Senior Manager)
Company: Karuna Therapeutics
Location: Boston, MA
Posted Feb 20, 2024
<p><strong>Position Strategic Sourcing Manager Senior Manager<strong><p> <p><strong> <strong><p> <p><strong>Position Summary<strong><p> <p>Karuna Therapeutics is seeking a Manager Senior Manager Strategic Sourcing for clinical and RampDrelated services This individual will be responsible for executing the operational goals and objectives of the Procurement Department and delivering on Karunas Procurement value proposition Assist the Director of Procurement to establish policies and procedures that will consistently deliver financial and operational efficiencies for a rapidly growing organization Bring a solid understanding of category management strategic sourcing and contract management Have the business acumen to identify contract terms that may pose certain liability to Karuna and collaborate with legal and other stakeholders to deliver RFPs and execute on statements of work with optimal contract terms for Karuna Build manage and nurture relationships with suppliers and clinical operations team to support clinical trial objectives<p> <p><br ><p><p><strong>Responsibilities<strong><p> <ul><li>Build and nurture stakeholder relationships by serving as a business partner by providing strategic sourcing and procurement services that meet expectations such as leading and managing RFPs helping stakeholders identify critical business requirements and providing valuable insights to stakeholders on procurement matters<li> <li>Perform analyses and use analytics to support strategic decisions and provide recommendations to stakeholders and suppliers on procurement matters<li> <li>Be proactive in seeking opportunities for process improvement cost efficiencies and developing category and sourcing strategies to leverage supplier capabilities to benefit Karuna<li> <li>Manage supplier performance including acting as an escalation point in the event of nonperformance for responsible categories<li> <li>Assist in establishing and maintaining Procurement policies and processes to consistently deliver value to the organization and to maintain regulatory compliance<li> <li>Work with appropriate stakeholders Clinical Operations Legal Compliance FPampA etc<li> <li>Assist with internal education of Oracles system for purchase orders<li> <li>Efficiently process contracts and purchase orders within Oracle Purchasing module<li> <ul><p><br ><br ><p><p><strong>Required Qualifications<strong><p> <ul><li>Geographically located in or willing to move to Greater Boston area<li> <li>5+ years of procurement experience is required preferably in a pharmaceutical SOX GMP or FDAregulated environment<li> <li>Bachelors degree preferably in Supply Chain Management Business Science or closely related discipline Will consider equivalent experience which includes a strong background in sourcing services for the Biotech or Pharmaceutical space<li> <li>Creative and excel at problem solving<li> <li>Demonstrated experience and success in strategic sourcing and negotiation with CROs for clinical trial management services<li> <li>Good business acumen and proven success with contract negotiation<li> <li>Demonstrated basic understanding of accounting and invoice processing<li> <li>Proficient with MS Excel and Word is a must<li> <li>Experience with Oracle Fusion a big plus<li> <li>Must be proactive results oriented and have strong attention to detail along with an ability to work independently with minimum supervision<li> <li>Demonstrate strong project management skills with the ability to also process and execute at the transactional level<li> <li>Strong communication skills with the ability to communicate effectively at any level and to work cross functionally with diverse teams and incorporate business stakeholder goals and objectives<li> <li>Must be able to problem solve while effectively handling multiple tasks<li> <li>Excellent verbal and written skills allowing for an open and effective dialogue throughout the company<li> <li>Attention to detail and quality are critical to success<li> <li>Highly accountable for the results and outcomes of their responsibilities and understands the impact of their efforts results and attitudes on others<li> <li>Uses teamwork to work cooperatively toward the most effective solutions championing the best ideas of team members and assisting where help is needed yet is capable of highly independent work when efficiency is required<li> <li>Resultsoriented individual who is highly motivated decisive flexible in thought and has the creativity to excel in and contribute to a rapidly growing company<li> <li>Forward thinking mindset with the ability to manage multiple projects and identify and resolve issues<li> <li>Broad experience in an emerging publicly traded company environment is a plus<li> <ul><p><br ><br ><p><p><strong> <strong><u>The successful candidate will also embody our values<u><p> <p><strong> <strong><p> <p><strong>Our purpose is to create value for those we have the privilege to serve<strong><p> <ul><li>We take pride in our work<li> <li>We keep our promises and deliver<li> <li>We are driven to meaningfully innovate<li> <li>We succeed through inclusion and teamwork<li> <ul><p><strong> <strong><p> <p>Karuna Therapeutics is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race color religion sex sexual orientation age gender identity or gender expression national origin disability or veteran status<p> <p><br ><br ><br ><br ><br ><br ><p><p>LIHybrid<p>
Associate Director/Director, Quality Systems and Documentation (Must Have GXP Experience)
Company: Scorpion Therapeutics
Location: Boston, MA
Posted Feb 22, 2024
We do not discriminate for reasons of race, color, religion, gender, national origin, age, sexual orientation, marital or veteran status, disability, or any other legally protected status. 21 CFR Part 11, EU Annex 11, GAMP5, etc.). Demonstrated experience in selecting, implementing, and managing electronic Quality Management Systems. reviewing batch records, managing quality events). Beginning October 13, 2021, Scorpion Therapeutics requires all new hires to be fully vaccinated against COVID-19. Demonstrated experience implementing and validating GxP computerized systems, including broad and deep knowledge of regulations, guidance, good practices on electronic record, electronic signatures, and data integrity (e.g. Strong leadership and management skills, with the ability to inspire and motivate cross-functional teams. Knowledge of GxP regulations, with prior experience supporting GMP operations (e.g. Ability to thrive in a fast-paced and dynamic environment, with a commitment to continuous improvement and innovation. If you are unable to receive the vaccine due to a disability or serious medical condition, or because of your sincerely held religious beliefs, you will have an opportunity to request a reasonable accommodation.
Staff Software Engineer
Company: Rezo Therapeutics
Location: San Francisco, CA
Posted Feb 21, 2024
<p><b>About Rezo Therapeutics<b><p> <p>Rezo is a different kind of biopharma company Our mission is to dramatically increase the success rate of drug development by building a diseaseagnostic fullyintegrated network biology platform that will redefine our understanding of human disease and ability to treat it <p> <p><br ><p> <p>Our Founders and members of the Board are a group of esteemed worldclass scientists from the University of California San Francisco Nevan Krogan Kevan Shokat Sourav Bandyopadhyay Natalia Jura as well as renowned biotech executives George Scangos and Norbert Bischofberger These leaders bring with them a strong track record of amazing discoveries and scientific breakthroughs leading to very successful companies and many FDA approved drugs <p> <p><br ><p> <p>Capitalizing on our Series A of $78M from toptier investors we are leveraging a unique integrated approach combining capabilities in genetics proteomics structural biology and AI to generate deep biological insights and novel therapeutic approaches<p> <p><br ><p> <p>Located in San Franciscos vibrant Mission Bay neighborhood Rezo is in close proximity to UCSF numerous urban amenities and outdoor recreational opportunities We recognize that realizing our mission depends as much on our people as it does on our science and are building a workplace that fosters collaboration respect and diversity where contributing to your teams success is valued as highly as individual achievements If youre passionate about team science and breaking down barriers to progress in drug development please consider joining us <p> <p><br ><p> <p><b>The Opportunity <b><p> <p>We are looking for an experienced and selfmotivated Staff Software Engineer to join our growing team Reporting to the Head of Computational Biology and AI this individual will be part of the team developing software solutions core to Rezos platform<p> <p><b>What Youll Do<b> <p><ul><li>Design develop test deploy maintain and enhance largescale software solutions<li> <li>Build and maintain databases and workflows in the cloud to access and process experimental data from multiple modalities eg proteomic genetic chemicalstructural biology <li> <li>Help optimize test and maintain ML code from modern deep learning frameworks eg PyTorch TensorFlow JAX Keras etc<li> <li>Develop documentation for internal pipelines as well as help establish best practices for code review and testing<li> <li>Collaborate with interdisciplinary teams to help build and maintain interactive data analysisvisualization interfaces <li> <li>Contribute to and balance multiple projectsstudies in parallel in a fastpaced environment<li> <ul><p><b>About You<b> <p><ul><li>Degree in computer science or a related technical field PhD with 3+ years of related experience Masters with 6+ years related experience or Bachelors with 8+ years<li> <li>Proficiency in programming languages eg Python SQL etc software best practices and software design<li> <li>Expertise in deploying and maintaining pipelines in the cloud<li> <li>Strong interpersonal communication and problemsolving skills and a desire to work within a dynamic multidisciplinary team environment<li> <li>Previous experience in data science analysis or visualization a plus<li> <li>Previous experience in bioinformatics systems biology drug discovery or computational chemistry a plus<li> <ul><p> <p><p><b>Compensation at Rezo<b><p> <p>The expected starting salary range for this position based in San Francisco California is $160000 $210000 Actual starting salary will be determined based on multiple jobrelated factors including a candidates skills education and experience the level at which they are hired market demand business needs and internal parity This role is eligible for participation in our Annual Discretionary Bonus Plan based on individual and company performance and our Equity Incentive Plan subject to the terms of those plans and associated policies This position is also eligible for the benefits detailed below<p> <p><br ><p> <p><b>Benefits at Rezo<b><p> <p>Medical HMO or PPO dental and vision insurance<p> <p>Discretionary time off policy<p> <p>Company holidays including summer and winter shutdown<p> <p>401k retirement savings program<p> <p>Commuter Mass Transit Benefit Program<p> <p>Healthcare Flexible Spending Account FSA<p> <p>Dependent care Flexible Spending Account FSA<p> <p>Parental leave<p> <p>Competitive compensation<p> <p>Flexible work schedule <p> <p><br ><p> <p><b>EEOC<b><p> <p>At Rezo we value a diverse equitable inclusive workplace and provide equal employment opportunity to all persons without regard to race color sex gender identity gender expression religion age national origin ancestry citizenship physical or mental disability medical condition family care status marital status domestic partner status sexual orientation genetic information military or veteran status or any other basis protected by federal state or local laws This statement covers all facets of employment and is especially important when it comes to growing our team <b> <b><p> <p><br ><p> <p><b>If you are wondering if youll belong at Rezo or are worried that you dont meet 100 of the qualifications for this role take a chance on us and yourself please apply<b><p> <p><br ><p> <p><b>SF Fair Chance Ordinance<b><p> <p>Pursuant to the San Francisco Fair Chance Ordinance Rezo considers qualified applicants with arrest and conviction records for employment<p> <p><p>
Data Innovation Architect (Manager)
Company: Karuna Therapeutics
Location: Boston, MA
Posted Feb 21, 2024
<p><strong>Position Data Innovation Architect Manager<strong><p> <p><strong> <strong><p> <p><strong> <strong><p> <p><strong>Position Summary<strong><p> <p>Karuna is seeking an experienced and motivated Data Innovation Architect to join our rapidly growing organization Reporting to the Director of Data Value Innovation amp Analytics this critical position will be responsible for development and support of processes which enable meaningful data analytics throughout the organization This role monitors and creates data integration and warehousing processes both directly and working in conjunction with third party technology partners<p> <p><br ><p><p><strong>Responsibilities<strong><p> <ul><li>Develop robust data integration processes that include automated testing to maintain the highest degree of data quality<li> <li>Monitor data processes and report any errors Diagnose and coordinate with responsible parties to correct process errors in a timely manner perform root cause analysis and implement plans for future preventative action<li> <li>Design and document database structures supporting a modern biotech data warehouse and analytic platform in a manner compliant with security privacy and data segregation imperatives<li> <li>Support and assist business data analysts with data extraction manipulation and visualization<li> <li>Oversee administration of user access controls and general administrative and support tasks related to database platforms and analytic tools<li> <li>Develop interactive reports and dashboards in conjunction with business stakeholders and thirdparty content creators<li> <li>Assist with the management of datarelated projects using Karuna ITs standard project methodology<li> <li>Contribute toward the ongoing development and evolution of standard operating procedures and provide support for internal and external reviews assessments and audits<li> <li>Assist with assessment of new technologies and where applicable with education and adoption<li> <ul><p><br ><br ><p><p><strong>Required Qualifications<strong><p> <ul><li>Proficient with the use of system integration automation and ETL toolsets and middleware and able to utilize these tools to build processes which maintain the highest data quality standards<li> <li>Adept at testing monitoring and troubleshooting errors in automated integration processes<li> <li>Experienced with the design and use of a modern data platform including both unstructured data lake and structured data and a data warehouse with relational starschema and columnar data stores<li> <li>Understand data SAAS AzureSnowflake consumption and billing models and how to maximize value minimize cost<li> <li>Strong understanding of security and privacy considerations as they relate to data management transfer and access in a biotech environment<li> <li>Proficient in the use of a variety of data query extraction and preparation tools<li> <li>Moderately skilled at administration of database and data visualization tools<li> <li>Able to create moderately complex interactive reports and dashboards using Tableau PowerBI or similar tools<li> <li>Excellent verbal and written skills allowing for an open and effective dialogue throughout the company<li> <li>Attention to detail and quality are critical to success<li> <li>Highly accountable for the results and outcomes of their responsibilities and understands the impact of their efforts results and attitudes on others<li> <li>Uses teamwork to work cooperatively toward the most effective solutions championing the best ideas of team members and assisting where help is needed yet is capable of highly independent work when efficiency is required<li> <li>Resultsoriented individual who is highly motivated decisive flexible in thought and has the creativity to excel in and contribute to a rapidly growing company<li> <li>Forward thinking mindset with the ability to manage multiple projects and identify and resolve issues<li> <li>Broad experience in an emerging publicly traded company environment is a plus<li> <ul><p><strong> <strong><u>The successful candidate will also embody our values<u><p> <p><strong> <strong><p> <p><strong>Our purpose is to create value for those we have the privilege to serve<strong><p> <ul><li>We take pride in our work<li> <li>We keep our promises and deliver<li> <li>We are driven to meaningfully innovate<li> <li>We succeed through inclusion and teamwork<li> <ul><p><strong> <strong><p> <p>Karuna Therapeutics is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race color religion sex sexual orientation age gender identity or gender expression national origin disability or veteran status<p> <p><br ><br ><br ><br ><br ><br ><br ><p><p>LIHybrid<p>
Associate Scientist/Scientist - Cheminformatics
Company: Terray Therapeutics
Location: Remote
Posted Feb 21, 2024
<p><b>Company Overview<b> <p><p>Terray is a biotechnology company with the technology data and mindset to radically change the way we discover and develop small molecule therapeutics We explore molecules and targets broadly and deeply with a sophisticated integration of ultrahigh throughput experimentation generative AI biology medicinal chemistry automation and nanotechnology Everything the company does is grounded in an iterative approach producing massive amounts of precise purposebuilt data mapping interactions between small molecules and causes of disease that gets increasingly valuable with each cycle of design and experimentation The companys platform uniquely blends experimentation and computation to improve the cost speed and success rate of small molecule drug discovery and development<p> <p><b>Position Summary<b> <p><p>Terray is currently seeking a motivated creative and experienced cheminformatics scientist As an integral member of our Computational and Data Sciences CDS team the candidate will help leverage our platform for emerging generative design applications through understanding and expanding our chemical space This position will be a part of the Molecular Design team and will work collaboratively with several other teams including Medicinal Chemistry Platform Chemistry Data Sciences Machine Learning and Compound Management <p> <p>The core responsibilities of this position are<p> <ul><li>Develop inhouse tools for molecular generation and data analysis to guide our hittolead and lead optimization efforts <li> <li>Contribute to the design and design methods for the multimillion scale libraries on our platform<li> <li>Ensure the data integrity of our chemical database and integrate it into our workflows<li> <li>Explore chemical space on our platform by developing new tools for enumeration and analysis <li> <ul><p><b>Experience and Qualifications<b> <p><p>Part of Terrays success is nurtured by a handson work environment where everyone is accountable vested in a vision of excellence and actively taking part in the success of the business Terray supports a positive work environment where employees can feel engaged recognized and empowered to be creative <p> <p><b>Required Qualifications<b> <p><ul><li>BSMSPhD in computational chemistry cheminformatics medicinal chemistry or a related field<li> <li>Experience with RDKit or related cheminformatics software Daylight OEChem OpenBabel etc<li> <li>Proficiency in Linux environment experience with database languages and experience with version control practices and tools<li> <li>Highly proficient in Python and the PyData stack numpy pandas scipy scikitlearn etc<li> <li>Experience with SQL and relational databases <li> <ul><p><b>Compensation Details<b> <p><p>$100000 $198000 annually depending on seniority participation in the Companys option plan 3 401K contribution full benefits<p>