Jobs at Flagship Pioneering

Positions 43,513

Flagship Pioneering is a venture capital firm that builds companies from the ground up in biotech, health tech, and data‑driven science. Founded in 2014, the firm invests in early‑stage startups that translate scientific breakthroughs into market‑able products. With offices in Boston and San Francisco, Flagship partners with founders to provide capital, strategic guidance, and operational expertise.

Hiring at Flagship spans technical, scientific, and business disciplines. Current openings include Software Engineer – AI, Data Scientist – Genomics, Product Manager – Digital Health, Bioinformatics Analyst, Regulatory Affairs Specialist, and Sales & Marketing roles for emerging therapeutics. Candidates can expect rigorous interview processes that test domain knowledge, problem‑solving, and cultural fit within a fast‑moving, collaborative environment.

Job Transparency’s Flagship listings give applicants the edge by revealing exact salary ranges, bonus structures, and employee sentiment scores. Access to real‑time market data lets you benchmark offers against industry averages and negotiate confidently. The platform also aggregates interview feedback, helping you tailor your preparation and highlight the skills most valued by Flagship’s hiring teams.

Communications and Public Affairs Project Manager

Company: Flagship Pioneering

Location: Cambridge

Posted Nov 06, 2023

Flagship Pioneering is hiring a Communications and Public Affairs Project Manager to coordinate and manage projects and events, support team operations, and prioritize initiatives. The ideal candidate will be organized, detail-oriented, and able to work independently across multiple projects. Responsibilities include managing tools and systems, coordinating team activities, organizing meetings, supporting events, managing a shared calendar, conducting research, and assisting with travel arrangements. Qualifications include a bachelor's degree, 3+ years of administrative or project management experience, strong organizational skills, proficiency in Microsoft Office, and experience in event planning. The candidate should be a team player with excellent judgment and the ability to work well with a distributed team.

VP/SVP Business Development and Strategy Lead

Company: Flagship Pioneering

Location: Cambridge

Posted Nov 04, 2023

Flagship Pioneering is a biotech company that invents and builds platform companies to address global challenges in health and sustainability. They unite life science innovation, company creation, and capital investment under one roof. Their companies have made significant contributions in areas like COVID-19 vaccines, disease cures, and sustainable agriculture. They have been recognized for their positive social and environmental impact. The VP/SVP Business Development and Strategy Lead role involves driving valuable business development deals between Flagship's platform companies and Pharma, aligning with long-term growth plans, and negotiating impactful deals.

Scientist I/II, Biomolecule Production

Company: Flagship Pioneering

Location: Cambridge

Posted Nov 04, 2023

Flagship Labs 97, Inc. (FL97) is a privately held, early-stage biotechnology company pioneering the use of artificial intelligence in scientific research. FL97 is backed by Flagship Pioneering, a company known for its long-term vision and resources. FL97 is currently seeking a detail-oriented Scientist - Biomolecule Production. The role involves overseeing the synthesis, purification, and characterization of nucleic acid products, enhancing production technologies, scheduling production runs, managing inventory, adhering to SOPs, and collaborating with R&D and software developers. The ideal candidate should have a strong background in molecular biology, nucleotide chemistry, and associated production processes, with at least 1 year of experience in a relevant industrial/biotechnology setting. Proficiency in therapeutic RNA synthesis is an advantage. Flagship Pioneering is a biotech company that invents and builds platform companies, resulting in over $90 billion in aggregate value. They have been recognized for their positive social and environmental impact.

Director, Platform Chemistry

Company: Flagship Pioneering

Location: Cambridge

Posted Nov 09, 2023

FL94 Inc. is a biotechnology company pioneering Protein Editing, creating small molecules that edit protein structure and function. They are seeking a Director of FL94 platform chemistry with extensive experience in synthetic methodologies, covalent chemistry, and small molecule discovery. The ideal candidate will have a PhD in organic chemistry, 10+ years of pharmaceutical experience, and the ability to build and manage high-performing teams. FL94 is backed by Flagship Pioneering, a biotech company that invents and builds platform companies for transforming human health and sustainability.

Data Engineer II, Bioinformatics

Company: Flagship Pioneering

Location: Cambridge

Posted Nov 06, 2023

Arana Biosciences, a company founded by Flagship Pioneering, is developing a new platform technology in agriculture by integrating molecular biology and plant biology. The Data Engineer II, Bioinformatics position involves designing and managing database systems, automating workflows, collaborating with scientists, and communicating insights. The role requires a B.S. or M.S. in computer science, extensive database experience, programming skills, and understanding of AWS services. Preferred qualifications include NGS pipeline development experience, API framework familiarity, and data visualization tools knowledge.

Scientist, Assay Development

Company: Flagship Pioneering

Location: Cambridge

Posted Nov 09, 2023

Arana Biosciences, a company founded by Flagship Pioneering, is seeking a detail-oriented Scientist for their Molecular Biology team. The role involves designing and optimizing RNA and protein detection assays, developing new methods, and collaborating with other team members. The ideal candidate should have a Ph.D. in molecular biology, genomics, or a similar field, with extensive experience in qPCR, protein extraction, and detection. Experience with plant material and liquid handling automation is a plus. Flagship Pioneering is a biotech company that invents and builds platform companies, resulting in over $90 billion in aggregate value.

(Senior) ML Research Scientist (Generative Modeling)

Company: Flagship Pioneering

Location: Cambridge

Posted Nov 09, 2023

Flagship Pioneering is a biotechnology company that invents and builds platform companies that change the world. They bring together the greatest scientific minds with entrepreneurial company builders and assemble the capital to allow them to take courageous leaps. The company has been recognized for its positive social and environmental impact and has founded companies that have addressed humanity's most urgent challenges.

Associate Director/Director, Computational Chemistry

Company: Flagship Pioneering

Location: Cambridge

Posted Nov 09, 2023

FL94 Inc., a biotechnology company backed by Flagship Pioneering, is seeking a director of computational chemistry. The role involves triaging and advancing multiple program opportunities, integrating chemistry, biology, DMPK, and machine learning. The ideal candidate should have expertise in docking algorithms, molecular dynamics, reactivity modeling, deep-learning/ML, and Python coding. A PhD in a relevant life science domain and at least 10 years of pharmaceutical small molecule experience are required. The company aims to transform healthcare and sustainability through protein editing.

Translational Co-op

Company: Flagship Pioneering

Location: Cambridge

Posted Nov 06, 2023

Ring Therapeutics Inc., a privately held biotechnology company, is seeking a Co-op to join their Translation team. The Co-op will work on validating a new gene therapy in vivo from January 10 to June 28. The successful candidate will gain hands-on experience in developing and conducting analytical assays, working with a scientific mentor. Key responsibilities include studying molecular biology of viruses, participating in immunological assays, culturing and maintaining cell lines, and developing IHC/IF staining. The ideal candidate should be enrolled in a master's degree program in Biotechnology or Bioengineering, have experience with aseptic techniques and mammalian cell culture, and be comfortable working independently and collaboratively.

Project Manager II

Company: Flagship Biosciences, Inc.

Location: Greater Denver Area

Posted Oct 23, 2023

Flagship Biosciences is a company that develops advanced computational tissue image analysis, clinical support, and diagnostics services to improve patient health. They are looking for a Project Manager II to manage projects and develop client relationships.

Research Associate, Delivery and Transformation

Company: Flagship Pioneering

Location: Cambridge

Posted Nov 06, 2023

Arana Biosciences, a company founded by Flagship Pioneering, is seeking a Research Associate with expertise in plant science, plant pathology, molecular biology, and microbiology. The role involves innovating, optimizing, and executing plant delivery and transformation methods, supporting various transformation workflows, and troubleshooting experimental problems. The ideal candidate should have experience with common plant transformation methods, expertise in handling plant tissues and molecular biology techniques, and strong communication and organizational skills.

QA Specialist II

Company: Flagship Biosciences, Inc.

Location: Greater Denver Area

Posted Oct 23, 2023

Flagship Biosciences is seeking a Quality Specialist II to ensure their laboratory and image analysis programs meet high-quality standards. The role involves designing and building components of the quality management system, managing day-to-day activities, writing and reviewing SOPs, and assisting during client audits. The candidate should have a science-related degree, 3-6 years of QA experience, and knowledge of FDA, CLIA, and GCP/GCLP regulations. Strong organization skills, attention to detail, and the ability to work independently in a fast-paced environment are essential. The company offers comprehensive benefits including health, dental, vision, and retirement plans.

Frequently Asked Questions

What is it like to work at Flagship Pioneering?
<strong>Mission‑driven culture</strong> – employees tackle long‑term scientific challenges and enjoy ownership in the companies they help build. Teams cross‑function between biology, engineering, and business, fostering rapid iteration. Flagship offers flexible schedules, generous equity packages, and a focus on continuous learning through internal workshops and external conferences.
What types of positions are available at Flagship Pioneering?
Flagship hires across four main tracks: <em>Biotech & Life Sciences</em> (e.g., Bioinformatics Analyst, Regulatory Affairs Specialist), <em>Data & AI</em> (Software Engineer, Data Scientist), <em>Product & Operations</em> (Product Manager, Program Manager), and <em>Commercial & Strategy</em> (Sales, Marketing, Corporate Development). Each role emphasizes domain expertise, analytical rigor, and the ability to thrive in a startup environment.
How can I stand out as an applicant for Flagship Pioneering?
Align your portfolio with Flagship’s mission by highlighting projects that translate science into marketable solutions. Showcase quantitative impact (e.g., algorithm performance metrics, assay validation data). Build a concise résumé that maps your experience to the job description, and prepare for case interviews by practicing problem‑solving under time constraints. Leverage alumni networks, attend virtual company events, and submit a tailored cover letter that cites specific Flagship initiatives.

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