Jobs at Flagship Pioneering

Positions 43,513

Flagship Pioneering is a venture capital firm that builds companies from the ground up in biotech, health tech, and data‑driven science. Founded in 2014, the firm invests in early‑stage startups that translate scientific breakthroughs into market‑able products. With offices in Boston and San Francisco, Flagship partners with founders to provide capital, strategic guidance, and operational expertise.

Hiring at Flagship spans technical, scientific, and business disciplines. Current openings include Software Engineer – AI, Data Scientist – Genomics, Product Manager – Digital Health, Bioinformatics Analyst, Regulatory Affairs Specialist, and Sales & Marketing roles for emerging therapeutics. Candidates can expect rigorous interview processes that test domain knowledge, problem‑solving, and cultural fit within a fast‑moving, collaborative environment.

Job Transparency’s Flagship listings give applicants the edge by revealing exact salary ranges, bonus structures, and employee sentiment scores. Access to real‑time market data lets you benchmark offers against industry averages and negotiate confidently. The platform also aggregates interview feedback, helping you tailor your preparation and highlight the skills most valued by Flagship’s hiring teams.

Research Associate II/Senior Research Associate, LNP Production

Company: Flagship Pioneering

Location: Cambridge

Posted Mar 20, 2024

FL85 is a biotechnology company seeking a highly talented individual to develop and optimize lipid nanoparticle (LNP) formulations. The company is committed to transforming the approach to information molecule therapeutics and has a strong track record of creating successful companies.

Bioinformatics Engineer

Company: Flagship Pioneering

Location: Cambridge

Posted Mar 17, 2024

Quotient Therapeutics is a biotech company that develops novel genomics platform and therapeutics for diseases with a large unmet need. They are seeking a Bioinformatics Engineer to join their team and work on designing, implementing, and operating robust genomic data processing pipelines.

Bioinformatics Data Engineer

Company: Flagship Pioneering

Location: Cambridge

Posted Mar 19, 2024

Apriori Bio, an early-stage biotechnology company, is seeking an Informatics & Data Engineering professional to join their team. The role involves exploring and analyzing data from high-throughput assays, creating data visualizations, and automating workflows. The ideal candidate should have a graduate degree in life sciences or a quantitative field, experience with statistical modeling, and proficiency in Python, SQL, and cloud platforms like AWS. The company offers comprehensive benefits, a dynamic work environment, and opportunities for professional growth.

(Senior) Machine Learning Scientist, Materials Characterization

Company: Flagship Pioneering

Location: Cambridge

Posted Mar 20, 2024

FL96, Inc., a privately held, early-stage company, is developing an AI and data-driven approach to materials discovery and development. Founded by Flagship Pioneering, it aims to accelerate the transition to a sustainable economy. The company is seeking a machine learning expert to design, build, and scale models for processing large-scale materials characterization data. The ideal candidate should have experience in chemical and materials characterization techniques, strong ML framework knowledge, and a PhD in a relevant field. Excellent communication and presentation skills are required.

Senior Scientist, Machine Learning

Company: Flagship Pioneering

Location: Cambridge

Posted Mar 21, 2024

FL85, a Flagship Pioneering backed biotech company, is seeking a Senior Machine Learning Scientist to join their team. The role involves developing innovative methods for molecular generation and optimization, large self-supervised pre-training, and active learning strategies. The ideal candidate will have a Ph.D. in a related field, 2+ years of experience in applying computational methods to scientific problems, and proficiency in Python and machine learning frameworks. The position offers the opportunity to develop domain expertise in nucleic acid medicines, deep relationship with a world-class lab team, and MLOps best practices.

(Senior) Machine Learning Scientist, Active Learning & Bayesian Optimization

Company: Flagship Pioneering

Location: Cambridge

Posted Mar 20, 2024

FL96, Inc. is a privately held company developing AI and data-driven approach to materials discovery and development. The company is founded by Flagship Pioneering, which has created over 100 groundbreaking companies. The job posting is for a machine learning engineer to work on materials discovery and development.

Machine Learning Scientist

Company: Flagship Pioneering

Location: Cambridge

Posted Mar 17, 2024

<div datablock=true dataeditor=c12n7 dataoffsetkey=dhkj500> <p><strong>Who We Are<strong><p> <p>Flagship Pioneering is a biotechnology company that invents and builds platform companies that change the world We bring together the greatest scientific minds with entrepreneurial company builders and assemble the capital to allow them to take courageous leaps Those big leaps in human health and sustainability exponentially accelerate scientific progress in areas ranging from cancer detection and treatment to naturepositive agriculture <p> <p> What sets Flagship apart is our ability to advance biotechnology by uniting life science innovation company creation and capital investment under one roof in a way that is largely without precedent Our scientific founders entrepreneurial leaders and professional capital managers are each aligned around an institutionalized process that enables us to innovate and transform for the benefit of people and planet <p> <p>Many of the companies Flagship has founded have addressed humanitys most urgent challenges vaccinating billions of people against COVID19 curing intractable diseases improving human health preempting illness and feeding the world by improving the resiliency and sustainability of agriculture <p> <p>Flagship has been recognized twice on FORTUNEs Change the World list an annual ranking of companies that have made a positive social and environmental impact through activities that are part of their core business strategies and has been twice named to Fast Companys annual list of the Worlds Most Innovative Companies <p> <p><strong>Position Summary<strong><p> <p>We believe deep integration of datadriven machine learning with experimental approaches is a core driver of the next generation of defining companies in health We imagine this will be driven by individuals from diverse scientific and machine learning backgrounds Thus we are open to all profiles with computational excellence<p> <p>We are seeking the most innovative and entrepreneurial Machine Learning Scientists You will join organizations at the early stages of our company creation process to develop innovative algorithmic methods leveraging both inhouse and external data to train and evaluate models while also deploying new algorithms into production and integrating deeply into experimental platforms to close feedback loops The successful candidate will work closely with experimental scientists to rapidly advance various scientific programs<p> <p><strong>Key responsibilities<strong><p> <ul><li>Develop or finetune deep learning architectures and hone them through deployment on experimental platforms<li> <li>Work with experimental groups to integrate modeling efforts into highimpact applications<li> <li>Develop productionquality code in a team setting and plan for deploying and training models at scale<li> <li>Present progress from scientific work in regular research meetings and prepare reports and slide decks for broader internal and external communication<li> <ul><p><strong>Qualifications<strong><p> <ul><li>PhD in computer science with a desire to collaborate with leading experimentalists or a PhD in scientific field plus demonstrated experience applying deep learning Exceptional candidates without PhDs will be considered<li> <li>Experience developing debugging and applying models using modern deep learning frameworks on GPUs in cloud environments<li> <li>Proficiency in Python and machine learning frameworks such as TensorFlow Pytorch andor JAX<li> <li>Desire to work across the entire data stack from data ingest to model deployment<li> <li>Curiosity and humility to work with scientific domain experts to identify and frame problems worth solving beyond existing benchmarks<li> <li>Energetic selfstarter with the ability to work effectively in a startup environment<li> <li>Excellent analytical skills and ability to synthesize amp communicate complex information rapidly and effectively<li> <ul><p><strong>Location <strong>Cambridge MA <p> <p>Flagship Pioneering and our ecosystem companies are <strong>committed to equal employment opportunity<strong> regardless of race color ancestry religion sex national origin sexual orientation age citizenship marital status disability gender identity or Veteran status<p> <p><strong>At Flagship we recognize there is no perfect candidate If you have some of the experience listed above but not all please apply anyway Experience comes in many forms skills are transferable and passion goes a long way We are dedicated to building diverse and inclusive teams and look forward to learning more about your unique background<strong><p> <div datablock=true dataeditor=c12n7 dataoffsetkey=cpe7800> <p><em><strong>Recruitment amp Staffing Agencies<strong> Flagship Pioneering and its affiliated Flagship Lab companies collectively FSP do not accept unsolicited resumes from any source other than candidates The submission of unsolicited resumes by recruitment or staffing agencies to FSP or its employees is strictly prohibited unless contacted directly by Flagship Pioneerings internal Talent Acquisition team Any resume submitted by an agency in the absence of a signed agreement will automatically become the property of FSP and FSP will not owe any referral or other fees with respect thereto<em><p> <div> <div>

Senior Dev Ops Engineer

Company: Flagship Pioneering

Location: Cambridge

Posted Mar 21, 2024

Flagship Labs 97 Inc. (FL97) is a privately held biotechnology company seeking a Senior DevOps Engineer. The role involves designing and deploying serverless architectures, implementing cloud-based solutions, developing infrastructure as code, orchestrating workflows, containerizing applications, and managing system configurations. FL97 is part of Flagship Pioneering, a company that invents and builds platform companies with the potential to transform human health or sustainability. The company is committed to equal employment opportunity and has been recognized for its positive social and environmental impact.

(Sr.) Scientist, GNN's

Company: Flagship Pioneering

Location: Cambridge

Posted Mar 17, 2024

FL96, Inc., a privately held, early-stage company backed by Flagship Pioneering, is seeking a Senior Machine Learning Scientist. The role involves developing and applying cutting-edge machine learning approaches to fuel and optimize FL96's proprietary material synthesis and assay platform. The ideal candidate should have a PhD in machine learning, computer science, or a related field, with a strong focus on deep learning applied to materials. They should have 3+ years of hands-on experience in implementing, evaluating, and tuning large deep learning models. Strong expertise in multiple programming paradigms and software libraries is required. Experience with graph neural networks, E3 invariant architectures, multi-fidelity machine learning, and AWS services is preferred. Flagship Pioneering is a biotechnology company that invents and builds platform companies, each with the potential for multiple products that transform human health or sustainability.

Senior Director, Strategy and Operations

Company: Flagship Pioneering

Location: Cambridge

Posted Mar 21, 2024

FL89, Inc., a privately held early-stage company, is seeking a Director of Strategy & Operations. The role involves developing corporate strategy, leading program updates, managing lab operations, and collaborating with the leadership team. The ideal candidate should have a PhD in Life Sciences, extensive experience in strategy and operations within the biotech or pharmaceutical industry, and a strong scientific background. They should also have experience in portfolio management, project management, and external alliances. Excellent communication and presentation skills are required, along with the ability to manage multiple projects and priorities.

Strategic Finance Analyst/Senior Analyst

Company: Flagship Pioneering

Location: Cambridge

Posted Mar 20, 2024

FL96, Inc. is an early-stage company developing an AI-driven approach to materials discovery and sustainability, founded by Flagship Pioneering. The company is seeking an experienced investment banker or private equity professional to build scenario analysis tools, create strategic presentations, and interface with related companies in the Flagship ecosystem. The ideal candidate will have at least 2 years of experience, strong communication skills, and the ability to work in a fast-paced, entrepreneurial setting.

VP, Machine Learning

Company: Flagship Pioneering

Location: Cambridge

Posted Mar 17, 2024

FL94 Inc., a biotechnology company specializing in Protein Editing, is seeking a Machine Learning Lead. The role involves setting the strategy for a team of data infrastructure and machine learning scientists, developing cutting-edge machine learning paradigms, and applying them to proprietary chemoproteomics and small molecule chemistry data sets. The ideal candidate should have deep expertise in machine learning, deep learning, and computational chemistry, with a proven track record in data science and machine learning. The role offers a unique opportunity to drive the strategy of an early-stage biotech and requires excellent leadership, project management, and communication skills.

Frequently Asked Questions

What is it like to work at Flagship Pioneering?
<strong>Mission‑driven culture</strong> – employees tackle long‑term scientific challenges and enjoy ownership in the companies they help build. Teams cross‑function between biology, engineering, and business, fostering rapid iteration. Flagship offers flexible schedules, generous equity packages, and a focus on continuous learning through internal workshops and external conferences.
What types of positions are available at Flagship Pioneering?
Flagship hires across four main tracks: <em>Biotech & Life Sciences</em> (e.g., Bioinformatics Analyst, Regulatory Affairs Specialist), <em>Data & AI</em> (Software Engineer, Data Scientist), <em>Product & Operations</em> (Product Manager, Program Manager), and <em>Commercial & Strategy</em> (Sales, Marketing, Corporate Development). Each role emphasizes domain expertise, analytical rigor, and the ability to thrive in a startup environment.
How can I stand out as an applicant for Flagship Pioneering?
Align your portfolio with Flagship’s mission by highlighting projects that translate science into marketable solutions. Showcase quantitative impact (e.g., algorithm performance metrics, assay validation data). Build a concise résumé that maps your experience to the job description, and prepare for case interviews by practicing problem‑solving under time constraints. Leverage alumni networks, attend virtual company events, and submit a tailored cover letter that cites specific Flagship initiatives.

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