Clinical Operations Manager

This position is listed on behalf of a partner company, who manages all applications and next steps. Our partner is looking for a Clinical Operations Manager based in the United States.

This is a leadership opportunity for an experienced clinical research professional to oversee and develop a team of Clinical Research Associates while supporting the successful delivery of clinical trials. The role combines people management, operational strategy, and quality oversight within a collaborative clinical research environment. You will play a key part in optimizing resources, improving processes, and ensuring operational excellence across multiple studies. This position is ideal for a motivated leader who enjoys coaching teams, solving complex challenges, and driving continuous improvement. You will partner with cross-functional stakeholders to support efficient study execution and maintain high standards of quality and compliance. This is a home-based role offering the opportunity to make a meaningful impact in global clinical research operations.

The Clinical Operations Manager will be responsible for leading clinical operations activities, developing team capabilities, and ensuring effective trial delivery through strong operational oversight.

• Lead, coach, mentor, and develop Clinical Research Associates across different levels of experience.
• Manage recruitment, onboarding, performance reviews, and ongoing professional development initiatives.
• Oversee resource allocation, workload planning, and team utilization across clinical studies.
• Partner with Project Managers and cross-functional teams to support successful study execution and resolve operational challenges.
• Monitor team performance using established operational metrics and implement actions to improve efficiency.
• Support the implementation of quality controls and contribute to the continuous improvement of clinical processes and systems.
• Prepare for and participate in audits, sponsor reviews, and regulatory inspections.
• Support feasibility activities for current and upcoming studies.
• Facilitate communication between project teams and investigational sites to ensure smooth trial operations.
• Contribute to business development activities through client discussions, networking opportunities, and operational input when needed.

Requirements:

The ideal candidate will bring strong clinical research expertise combined with proven leadership abilities and a passion for developing high-performing teams.

• Advanced degree in Medicine, Pharmacy, Life Sciences, or a related field, or an equivalent combination of education, training, and experience.
• Minimum of 5 years of experience in the clinical research industry, including demonstrated people management or team leadership experience.
• Previous independent experience as an onsite Clinical Research Associate (CRA) is required.
• Experience managing, coaching, or mentoring clinical research professionals within a CRO, sponsor, or similar environment.
• Strong leadership, communication, coaching, and employee development skills.
• Experience with resource planning, workload management, and performance management processes.
• Solid knowledge of ICH-GCP guidelines, regulatory requirements, and clinical trial operations.
• Experience supporting audits, inspections, and quality improvement initiatives is preferred.
• Excellent organizational, analytical, and problem-solving capabilities.
• Proficiency with Microsoft Office tools and clinical research systems.
• Advanced English proficiency, both written and spoken.
• Ability to build trust, encourage collaboration, and create a positive team environment.

Benefits:

• Home-based position offering flexibility within the United States.
• Opportunity to lead and influence clinical operations teams within a global research environment.
• Competitive compensation package aligned with experience and qualifications.
• Professional growth opportunities through leadership development and continuous learning.
• Collaborative culture focused on quality, innovation, and operational excellence.
• Access to employee benefits and programs designed to support professional and personal well-being.