CTMS Operations Manager

This position is posted by Jobgether on behalf of a partner company. We are currently looking for a CTMS Operations Manager in United States.

In this role, you will own the governance, performance, and operational integrity of a critical clinical trial management system that supports large-scale research operations across global health initiatives. You will act as both a technical leader and people manager, ensuring CTMS configurations, study builds, and platform changes are accurate, compliant, and aligned with regulatory and operational standards. This position plays a key role in maintaining system reliability, enabling high-quality clinical operations, and supporting data-driven decision-making across study teams. You will collaborate closely with study start-up, clinical operations, QA, vendors, and analytics teams to ensure seamless system integration and execution. Operating in a remote-first environment, you will lead a team responsible for CTMS operations while continuously improving processes, reporting capabilities, and system governance. This is a highly impactful role at the intersection of clinical systems, operational excellence, and regulatory compliance.

• Own CTMS platform governance, including final approval of system builds, configurations, and release readiness
• Define, maintain, and enforce configuration standards, naming conventions, and system build quality controls
• Lead CTMS change control processes, validation activities, upgrade testing, and audit readiness preparation
• Manage CTMS Operations team, including hiring, training, performance management, workload allocation, and career development
• Oversee CTMS-sourced reporting, define KPIs, and drive continuous improvement of operational dashboards and insights
• Serve as primary liaison between CTMS vendors and internal stakeholders including SSU, Study Ops, QA, and Analytics teams
• Coordinate system integrations, issue resolution, and cross-functional operational alignment
• Maintain CTMS SOPs, runbooks, and training documentation to ensure consistency and compliance
• Represent CTMS operations in governance forums, study readiness reviews, and escalation processes

Requirements:

• Bachelor’s degree or equivalent practical experience in clinical operations, life sciences, or related field
• 5+ years of experience working with CTMS or clinical systems, with at least 2+ years in a leadership or team management role
• Strong expertise in CTMS configuration, study build processes, and system governance (experience with platforms such as Veeva, Florence, Conductor, or similar preferred)
• Solid understanding of clinical operations workflows, including SSU, study execution, and QA processes
• Familiarity with ICH-GCP guidelines, SOPs, and regulatory audit requirements
• Proven people management experience, including coaching, performance management, and team development
• Strong cross-functional stakeholder management skills across technical, operational, and vendor teams
• Technical fluency to support system testing, integrations, and structured troubleshooting
• Excellent communication, documentation, and attention to detail skills
• Ability to operate effectively in a remote, fast-paced, and highly collaborative environment

Benefits:

• Competitive salary range of $90,000 to $120,000 USD annually
• 100% employer-paid medical, dental, and vision insurance options
• Paid time off and company-paid holidays
• Health Savings Account (HSA) and Flexible Spending Accounts (FSA)
• Bi-weekly employer HSA contributions
• Company-paid short-term and long-term disability coverage
• 401(k) retirement plan with company match
• Fully remote work within the United States
• Opportunity to lead critical clinical systems supporting global research initiatives
• Inclusive and mission-driven work environment focused on improving global health access