Job Description
Passionate about precision medicine and advancing the healthcare industry?
Recent advancements in underlying technology have finally made it possible for AI to impact clinical care in a meaningful way. Tempus' proprietary platform connects an entire ecosystem of real-world evidence to deliver real-time actionable insights to physicians providing critical information about the right treatments for the right patients at the right time.
We are looking for a highly analytical self-motivated and solution-oriented scientist with a strong background in analyzing large-scale multi-omic molecular and real-world clinical datasets to join our Discover Data Science team supporting Medical Affairs. In this role you will work directly with the Tempus Medical Sciences Team and oncology research leaders to understand their goals and translate their scientific questions into insight generation. Your work will directly enhance Tempus’ research capabilities and empower our teams and partners to generate actionable insights for patient care.
Responsibilities:
Lead and contribute to research projects in support of research initiatives within R&D and Medical Affairs leveraging large-scale real-world clinical and multi-omic molecular data.
Present insights from research studies to external research partners through formal presentations and communicate research findings effectively.
Stay updated on methodological advancements in real-world studies next generation sequencing (DNA/RNA) and oncology guidelines.
Communicate analytical results and scientific findings clearly to audiences with varying levels of technical and genomics expertise.
Participate in publications and podium activities.
Required Experience:
3+ years experience in industry or academia following completion of PhD degree in quantitative NGS-related disciplines (e.g. Computational Biology Genetics or similar). Alternatively a PhD in computational biology with a strong record of multi-omic high-throughput sequencing data analysis
Computational skills using R and SQL especially relevant statistical tools and packages.
Experience deriving oncology-specific clinical insights using genomic data and deriving real-world endpoints using time-to-event methodologies within a retrospective database.
Excellent project management skills with proven ability to collaborate with teams of multi-disciplinary scientists to define and execute analysis plans to address scientific questions using omics datasets (genomics transcriptomics).
Thrive in a fast-paced environment and willing to shift priorities seamlessly
A collaborative mindset coupled with a genuine eagerness to learn and a steadfast dedication to maintaining integrity in all endeavors.
Nice to have:
Experience integrating molecular data with real-world evidence and longitudinal clinical outcomes.
Experience with AWS and/or Bigquery and/or Google Cloud Platform (GCP)
Proficiency in machine learning techniques with a nuanced understanding of the strengths and limitations of various approaches particularly regarding predictive and prognostic algorithms in medical research.
CHI: $100000-$160000 USD
NYC: $115000-$175000 USD
The expected salary range above is applicable if the role is performed from Illinois and may vary for other locations (California Colorado New York). Actual salary may vary based on qualifications and experience. Tempus offers a full range of benefits which may include incentive compensation restricted stock units medical and other benefits depending on the position.
We are an equal opportunity employer. We do not discriminate on the basis of race religion color national origin gender sexual orientation age marital status veteran status or disability status.
Top Skills
What the Team is Saying










What We Do
We bring together one of the world’s largest libraries of multimodal clinical and molecular data with a robust suite of AI tools to help physicians personalize care in real time connect patients with therapies and clinical trials and enable partners to accelerate discovery and development of new treatments. With ~8 million de-identified research records and 350+ petabytes of data Tempus partners with more than half of U.S. oncologists and the majority of the top 20 global pharma companies. Our teams are pioneering work across oncology neurology psychiatry cardiology and beyond—transforming how care is delivered and therapies are developed. At Tempus every role contributes to our mission: to help each patient benefit from the experiences of those who came before. For more information visit tempus.com.
Why Work With Us
We’re looking for people who can change the world. People who question the status quo and refuse to shy away from tough problems. For builders who are never done building and the learners who are never done learning. Passionate individuals with undying curiosity who want to take on one of the greatest challenges humanity has ever faced—head on.
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Tempus AI Offices
Hybrid Workspace
Employees engage in a combination of remote and on-site work.
Most of the team follows a hybrid policy with some roles allowing for a fully remote arrangement and some roles being onsite only.











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Date Posted
04/23/2026
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